Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
go back to main search page
Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO (PMID:32276428) UniProt PMID:32276428 NCBI chrNW_004955565:2,006,154...2,029,921 JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004955459:25,649...30,215
Ensembl chrNW_004955459:25,649...30,215 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955404:30,229,632...30,235,677
Ensembl chrNW_004955404:30,229,632...30,235,679 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955450:7,876,572...7,885,305
Ensembl chrNW_004955450:7,876,522...7,886,581 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004955462:9,440,019...9,451,875
Ensembl chrNW_004955462:9,439,987...9,455,268 		JBrowse link
G Grn granulin precursor involved_in ISO (PMID:28073925) UniProt PMID:28073925 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004955404:557,090...573,532
Ensembl chrNW_004955404:557,862...573,379 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004955572:1,423,048...1,464,443
Ensembl chrNW_004955572:1,422,981...1,462,622 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955452:17,518,345...17,549,112
Ensembl chrNW_004955452:17,529,115...17,549,664 		JBrowse link
G Snapin SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chrNW_004955545:306,546...308,229
Ensembl chrNW_004955545:306,546...308,229 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004955432:18,619,418...18,644,876
Ensembl chrNW_004955432:18,619,413...18,639,151 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004955481:4,772,394...4,776,524
Ensembl chrNW_004955481:4,772,401...4,776,524 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chrNW_004955406:37,279,885...37,299,196
Ensembl chrNW_004955406:37,279,694...37,314,251 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chrNW_004955533:1,522,878...1,796,673
Ensembl chrNW_004955533:1,522,795...1,797,116 		JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in ISO (PMID:32966160)
(MGI:7338895|PMID:35469906)		 UniProt PMID:32966160 PMID:35469906 MGI:7338895 NCBI chrNW_004955426:19,498,942...19,530,628
Ensembl chrNW_004955426:19,498,942...19,530,628 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chrNW_004955514:434,283...453,239
Ensembl chrNW_004955514:434,285...453,239 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chrNW_004955581:319,942...335,112
Ensembl chrNW_004955581:319,942...335,112 		JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) involved_in ISO (PMID:32172343) UniProt PMID:32172343 NCBI chrNW_004955408:14,495,165...14,815,648
Ensembl chrNW_004955408:14,492,752...14,595,122 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:15163665) BHF-UCL PMID:15163665 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619 		JBrowse link
G Acp2 acid phosphatase 2, lysosomal acts_upstream_of_or_within ISO (PMID:9228031)
(PMID:15604265)		 MGI PMID:9228031 PMID:15604265 NCBI chrNW_004955422:954,108...961,522
Ensembl chrNW_004955422:954,089...961,522 		JBrowse link
G Aktip AKT interacting protein involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955433:11,237,717...11,248,638
Ensembl chrNW_004955433:11,237,717...11,248,249 		JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:30786955), (PMID:9931340) MGI PMID:9931340 PMID:30786955 NCBI chrNW_004955425:22,792,616...23,051,509
Ensembl chrNW_004955425:22,792,616...23,051,737 		JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within ISO (PMID:37871017) MGI PMID:37871017 NCBI chrNW_004955460:10,997,554...11,009,435
Ensembl chrNW_004955460:10,996,796...11,009,525 		JBrowse link
G Arsg arylsulfatase G acts_upstream_of_or_within ISO (PMID:26975023) MGI PMID:26975023 NCBI chrNW_004955478:4,326,669...4,475,559
Ensembl chrNW_004955478:4,341,826...4,434,542 		JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO (PMID:18497889) MGI PMID:18497889 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO (PMID:10440905)
(PMID:10191119), (PMID:10527801)
(PMID:15588329)		 MGI PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein acts_upstream_of_or_within ISO (PMID:15459177) MGI PMID:15459177 NCBI chrNW_004955404:30,229,632...30,235,677
Ensembl chrNW_004955404:30,229,632...30,235,679 		JBrowse link
G Cln6 CLN6 transmembrane ER protein acts_upstream_of_or_within ISO (PMID:26681805), (PMID:9600738) MGI PMID:9600738 PMID:26681805 NCBI chrNW_004955450:7,876,572...7,885,305
Ensembl chrNW_004955450:7,876,522...7,886,581 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) MGI PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 NCBI chrNW_004955403:57,926,711...57,938,698
Ensembl chrNW_004955403:57,924,873...57,938,690 		JBrowse link
G Clvs1 clavesin 1 involved_in ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chrNW_004955444:17,319,905...17,515,397
Ensembl chrNW_004955444:17,319,905...17,515,421 		JBrowse link
G Clvs2 clavesin 2 involved_in ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chrNW_004955436:4,758,749...4,823,383
Ensembl chrNW_004955436:4,758,743...4,823,383 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004955462:9,440,019...9,451,875
Ensembl chrNW_004955462:9,439,987...9,455,268 		JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955414:21,954,103...21,977,877
Ensembl chrNW_004955414:21,954,103...21,977,875 		JBrowse link
G Gaa alpha glucosidase involved_in
acts_upstream_of_or_within		 ISO (PMID:7717400)
(PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)
(PMID:15169761), (PMID:9668092)		 BHF-UCL
MGI		 PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 More... NCBI chrNW_004955506:2,764,959...2,783,231
Ensembl chrNW_004955506:2,764,959...2,783,231 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:27378698)
(MGI:5817293|PMID:27378698)		 UniProt PMID:27378698 MGI:5817293 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO (PMID:21719679) UniProt PMID:21719679 NCBI chrNW_004955405:37,107,902...37,136,993
Ensembl chrNW_004955405:37,107,542...37,136,993 		JBrowse link
G Grn granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377 		JBrowse link
G Hexa hexosaminidase subunit alpha acts_upstream_of_or_within ISO (PMID:7937929), (PMID:9103204)
(PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)
(PMID:8747922)
(PMID:8896570), (PMID:9184660)		 MGI PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... NCBI chrNW_004955450:4,790,342...4,806,862
Ensembl chrNW_004955450:4,790,268...4,806,734 		JBrowse link
G Hexb hexosaminidase subunit beta acts_upstream_of_or_within ISO (PMID:8896570), (PMID:9184660)
(PMID:8789434), (PMID:9645704)		 MGI PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 NCBI chrNW_004955425:25,942,341...25,961,312
Ensembl chrNW_004955425:25,942,278...25,961,312 		JBrowse link
G Hook1 hook microtubule tethering protein 1 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955464:47,895...129,414
Ensembl chrNW_004955464:47,732...129,414 		JBrowse link
G Hook2 hook microtubule tethering protein 2 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955415:31,855,183...31,865,413
Ensembl chrNW_004955415:31,853,091...31,865,450 		JBrowse link
G Hook3 hook microtubule tethering protein 3 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955457:13,149,013...13,249,524
Ensembl chrNW_004955457:13,149,013...13,249,321 		JBrowse link
G Hps1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chrNW_004955507:4,408,428...4,433,219
Ensembl chrNW_004955507:4,409,035...4,429,348 		JBrowse link
G Hps4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:12663659) UniProt PMID:12663659 NCBI chrNW_004955455:1,048,946...1,076,097
Ensembl chrNW_004955455:1,049,992...1,073,950 		JBrowse link
G Hsd17b1 hydroxysteroid 17-beta dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:29180785) MGI PMID:29180785 NCBI chrNW_004955451:16,449,333...16,452,036
Ensembl chrNW_004955451:16,449,683...16,451,945 		JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19751987)
(PMID:9097952)		 MGI PMID:9097952 PMID:19751987 NCBI chrNW_004955514:474,830...488,007
Ensembl chrNW_004955514:475,731...488,007 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO (MGI:4887551|PMID:19177150) UniProt PMID:19177150 MGI:4887551 NCBI chrNW_004955414:19,228,615...19,235,523
Ensembl chrNW_004955414:19,228,615...19,247,765 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:25807535)
(PMID:29374543)		 MGI PMID:25807535 PMID:29374543 NCBI chrNW_004955425:3,718,291...3,755,942
Ensembl chrNW_004955425:3,718,206...3,756,142 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Lyset lysosomal enzyme trafficking factor involved_in ISO (PMID:36096887) UniProt PMID:36096887 NCBI chrNW_004955438:15,305,699...15,309,851 JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:9368050)
(PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chrNW_004955492:4,161,976...4,371,637
Ensembl chrNW_004955492:4,209,749...4,369,762 		JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in ISO (PMID:21719679) UniProt PMID:21719679 NCBI chrNW_004955564:176,230...226,555
Ensembl chrNW_004955564:176,230...228,587 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:26681805)
(PMID:35025759)
(PMID:24423645), (PMID:35025759)		 MGI PMID:24423645 PMID:26681805 PMID:35025759 NCBI chrNW_004955428:13,519,285...13,548,007
Ensembl chrNW_004955428:13,519,277...13,544,695 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:22692423) UniProt PMID:22692423 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694 		JBrowse link
G Myo7a myosin VIIA involved_in ISO (PMID:16001398) UniProt PMID:16001398 NCBI chrNW_004955414:14,576,356...14,647,500
Ensembl chrNW_004955414:14,576,356...14,647,500 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) MGI PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 NCBI chrNW_004955451:16,445,338...16,449,243
Ensembl chrNW_004955451:16,445,338...16,450,062 		JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta acts_upstream_of_or_within ISO (PMID:25365221) MGI PMID:25365221 NCBI chrNW_004955588:648,180...679,374
Ensembl chrNW_004955588:648,180...679,374 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within ISO (PMID:16368712)
(PMID:16542649)		 MGI PMID:16368712 PMID:16542649 NCBI chrNW_004955452:17,518,345...17,549,112
Ensembl chrNW_004955452:17,529,115...17,549,664 		JBrowse link
G Snapin SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chrNW_004955545:306,546...308,229
Ensembl chrNW_004955545:306,546...308,229 		JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:25365221)
(PMID:37871017)
(PMID:28237315), (PMID:31637311)
(PMID:26284655)		 MGI PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 PMID:37871017 NCBI chrNW_004955416:11,084,448...11,168,478
Ensembl chrNW_004955416:11,086,176...11,168,332 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in ISO (PMID:24448649) UniProt PMID:24448649 NCBI chrNW_004955543:547,037...561,073
Ensembl chrNW_004955543:547,037...561,073 		JBrowse link
G Tfeb transcription factor EB involved_in
acts_upstream_of_or_within		 ISO (PMID:23434374)
(PMID:31637311)
(PMID:22692423), (PMID:32612235), (PMID:32753672), (PMID:35662396)		 UniProt
MGI		 PMID:22692423 PMID:23434374 PMID:31637311 PMID:32612235 PMID:32753672 More... NCBI chrNW_004955437:8,102,241...8,141,001
Ensembl chrNW_004955437:8,098,976...8,141,001 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:25066864) MGI PMID:25066864 NCBI chrNW_004955432:18,619,418...18,644,876
Ensembl chrNW_004955432:18,619,413...18,639,151 		JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chrNW_004955422:16,899,730...16,923,962
Ensembl chrNW_004955422:16,900,239...16,923,978 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 acts_upstream_of_or_within ISO (PMID:15483130) MGI PMID:15483130 NCBI chrNW_004955414:22,324,847...22,330,912
Ensembl chrNW_004955414:22,324,856...22,330,912 		JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chrNW_004955416:7,772,653...7,780,408
Ensembl chrNW_004955416:7,772,653...7,782,542 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chrNW_004955448:207,582...240,264
Ensembl chrNW_004955448:204,991...240,160 		JBrowse link
G Washc5 WASH complex subunit 5 acts_upstream_of_or_within ISO (PMID:30061306) MGI PMID:30061306 NCBI chrNW_004955461:145,993...199,274
Ensembl chrNW_004955461:145,993...199,903 		JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within ISO (PMID:25365221)
(PMID:37871017)		 MGI PMID:25365221 PMID:37871017 NCBI chrNW_004955466:2,389,893...2,453,487
Ensembl chrNW_004955466:2,390,527...2,451,664 		JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730 		JBrowse link
G Flcn folliculin involved_in ISO (PMID:37079666) UniProt PMID:37079666 NCBI chrNW_004955577:672,774...694,140
Ensembl chrNW_004955577:672,410...694,140 		JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO (PMID:37079666) UniProt PMID:37079666 NCBI chrNW_004955408:3,117,258...3,238,223
Ensembl chrNW_004955408:3,117,277...3,238,223 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:24448649), (PMID:32612235) UniProt PMID:24448649 PMID:32612235 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:12132654) UniProt PMID:12132654 NCBI chrNW_004955493:6,815,148...6,820,295
Ensembl chrNW_004955493:6,811,430...6,826,485 		JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO (PMID:12743369) MGI PMID:12743369 NCBI chrNW_004955414:14,576,356...14,647,500
Ensembl chrNW_004955414:14,576,356...14,647,500 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:11544318) MGI PMID:11544318 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Srpx sushi repeat containing protein X-linked acts_upstream_of_or_within ISO (PMID:19368996) MGI PMID:19368996 NCBI chrNW_004955601:286,092...364,235
Ensembl chrNW_004955601:286,069...364,235 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP ribosylation factor like GTPase 8B involved_in ISO (PMID:21802320) UniProt PMID:21802320 NCBI chrNW_004955421:8,231,337...8,276,907
Ensembl chrNW_004955421:8,231,582...8,276,907 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO (PMID:28779020)
(MGI:6103777|PMID:28779020)		 UniProt PMID:28779020 MGI:6103777 NCBI chrNW_004955457:6,749,226...6,841,855
Ensembl chrNW_004955457:6,748,534...6,842,489 		JBrowse link
G Pla2g5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chrNW_004955452:662,281...721,507
Ensembl chrNW_004955452:710,271...723,142 		JBrowse link
G Rab20 RAB20, member RAS oncogene family involved_in ISO (PMID:21255211) UniProt PMID:21255211 NCBI chrNW_004955404:2,087,580...2,088,545 JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISO (PMID:21255211)
(MGI:5467668|PMID:23197834)		 UniProt
ParkinsonsUK-UCL		 PMID:21255211 PMID:23197834 MGI:5467668 NCBI chrNW_004955481:4,441,290...4,445,969
Ensembl chrNW_004955481:4,441,407...4,445,969 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family involved_in ISO (PMID:21255211) UniProt PMID:21255211 NCBI chrNW_004955412:10,224,074...10,240,270
Ensembl chrNW_004955412:10,224,074...10,240,270 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:21255211) UniProt PMID:21255211 NCBI chrNW_004955429:15,103,792...15,167,498 JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (MGI:5693670|PMID:26317472) UniProt PMID:26317472 MGI:5693670 NCBI chrNW_004955514:434,283...453,239
Ensembl chrNW_004955514:434,285...453,239 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO (PMID:26284655) MGI PMID:26284655 NCBI chrNW_004955416:11,084,448...11,168,478
Ensembl chrNW_004955416:11,086,176...11,168,332 		JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) ARUK-UCL PMID:19787053 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISO (PMID:28073925)
(MGI:5905514|PMID:28073925)		 UniProt PMID:28073925 MGI:5905514 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:32753672) UniProt PMID:32753672 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:25720963) UniProt PMID:25720963 NCBI chrNW_004955563:1,703,408...1,712,908
Ensembl chrNW_004955563:1,703,416...1,745,996 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in ISO (PMID:25720963), (PMID:32753672) UniProt PMID:25720963 PMID:32753672 NCBI chrNW_004955437:18,323,852...18,377,815
Ensembl chrNW_004955437:18,323,857...18,377,815 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (PMID:36161949) MGI PMID:36161949 NCBI chrNW_004955493:6,506,449...6,514,308
Ensembl chrNW_004955493:6,505,230...6,514,307 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO (PMID:23569283) UniProt PMID:23569283 NCBI chrNW_004955447:15,538,958...15,543,885
Ensembl chrNW_004955447:15,538,958...15,543,892 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (MGI:5693670|PMID:26317472)
(PMID:35750034)		 UniProt PMID:26317472 PMID:35750034 MGI:5693670 NCBI chrNW_004955514:434,283...453,239
Ensembl chrNW_004955514:434,285...453,239 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO (PMID:28013294) UniProt PMID:28013294 NCBI chrNW_004955482:6,333,282...6,352,369
Ensembl chrNW_004955482:6,332,366...6,353,834 		JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chrNW_004955417:13,574,493...13,625,669
Ensembl chrNW_004955417:13,574,721...13,625,313 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377 		JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chrNW_004955417:13,574,493...13,625,669
Ensembl chrNW_004955417:13,574,721...13,625,313 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004955432:18,619,418...18,644,876
Ensembl chrNW_004955432:18,619,413...18,639,151 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:23160154) MGI PMID:23160154 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12482
    cellular process 11573
      cellular component organization or biogenesis 5382
        cellular component organization 5258
          organelle organization 2910
            vacuole organization 188
              lytic vacuole organization 86
                lysosome organization + 86
paths to the root