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ONTOLOGY REPORT - ANNOTATIONS

Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis


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lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr2B:28,624,800...28,629,543 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:11722572) UniProt PMID:11722572
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 1:142,974,260...142,987,071
Ensembl chr 1:146,758,325...146,770,978 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,442,507...94,464,061
Ensembl chr13:113,507,401...113,530,457 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:109,700,185...109,743,579
Ensembl chr  X:119,886,982...119,929,896 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
MGI		 PMID:20920792 GO_REF:0000107 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,412,229...28,416,840
Ensembl chr17:28,914,604...28,919,194 		JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,734,640...176,771,476
Ensembl chr 1:181,037,050...181,056,841 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,811,728...2,192,018
Ensembl chr15:25,181,386...25,523,774 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,357,549...76,398,571
Ensembl chr 5:81,743,254...81,784,565 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030 		JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105 		JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:155,952,876...156,234,942
Ensembl chr 5:162,646,009...162,862,268 		JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188 		JBrowse link
G ACP2 acid phosphatase 2, lysosomal acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9228031)
(PMID:15604265)		 MGI
TreeGrafter		 PMID:9228031 PMID:15604265 GO_REF:0000118 NCBI chr11:47,185,611...47,195,174
Ensembl chr11:47,738,845...47,748,450 		JBrowse link
G ACP3 acid phosphatase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:129,392,396...129,465,962
Ensembl chr 3:136,713,816...136,764,655 		JBrowse link
G ACP4 acid phosphatase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909 		JBrowse link
G AKTIP AKT interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,731,652...33,743,571
Ensembl chr16:52,815,559...52,827,750 		JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30786955), (PMID:9931340) Ensembl
MGI		 PMID:9931340 PMID:30786955 GO_REF:0000107 NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205 		JBrowse link
G AP5Z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:37871017) MGI
Ensembl		 PMID:37871017 GO_REF:0000107 NCBI chr 7:5,027,987...5,044,215
Ensembl chr 7:5,068,846...5,085,087 		JBrowse link
G ARSG arylsulfatase G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26975023) MGI
Ensembl		 PMID:26975023 GO_REF:0000107 NCBI chr17:62,195,977...62,379,362
Ensembl chr17:67,588,347...67,768,454 		JBrowse link
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18497889) Ensembl
MGI		 PMID:18497889 GO_REF:0000107 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G CHMP5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO (PMID:16567502) MGI PMID:16567502 NCBI chr 9:33,043,148...33,059,564
Ensembl chr 9:33,851,377...33,867,942 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15459177) Ensembl
TreeGrafter
MGI		 PMID:15459177 GO_REF:0000107 GO_REF:0000118 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26681805), (PMID:9600738) Ensembl
TreeGrafter
MGI		 PMID:9600738 PMID:26681805 GO_REF:0000107 GO_REF:0000118 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10087069), (PMID:7613514), (PMID:8144516), (PMID:8160780) Ensembl
MGI		 PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 NCBI chr 8:5,587,875...5,606,883
Ensembl chr 8:1,658,694...1,700,754 		JBrowse link
G CLVS1 clavesin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:57,703,459...57,921,997
Ensembl chr 8:59,252,291...59,630,784 		JBrowse link
G CLVS2 clavesin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:120,784,849...120,858,655
Ensembl chr 6:124,907,667...124,975,839 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 1:142,974,260...142,987,071
Ensembl chr 1:146,758,325...146,770,978 		JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:6,345,227...6,368,675
Ensembl chr11:6,027,300...6,050,850 		JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15169761), (PMID:9668092)
(PMID:10547605), (PMID:11328962), (PMID:12115977), (PMID:9384603)		 Ensembl
TreeGrafter
MGI		 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... GO_REF:0000107 GO_REF:0000118 NCBI chr17:74,188,296...74,206,593
Ensembl chr17:79,723,699...79,741,839 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:99,328,026...99,418,151
Ensembl chr12:102,729,615...102,816,560 		JBrowse link
G GRN granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10591619), (PMID:14972652), (PMID:9302266), (PMID:9645704)
(PMID:8896570), (PMID:9184660)
(PMID:8747922)
(PMID:7937929), (PMID:9103204)		 Ensembl
MGI		 PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 NCBI chr15:51,235,123...51,326,832
Ensembl chr15:70,057,943...70,090,688
Ensembl chr15:70,057,943...70,090,688 		JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8896570), (PMID:9184660)
(PMID:8789434), (PMID:9645704)		 Ensembl
MGI		 PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693 		JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:59,072,565...59,134,191
Ensembl chr 1:60,777,769...60,839,384 		JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,325,578...12,340,754
Ensembl chr19:13,070,289...13,082,612 		JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,145,427...42,278,727
Ensembl chr 8:39,595,762...39,711,043 		JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chr10:95,030,626...95,061,415
Ensembl chr10:98,526,113...98,552,922 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:7,513,397...7,545,782
Ensembl chr22:25,236,360...25,268,699 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:29180785) MGI PMID:29180785 NCBI chr17:14,760,856...14,763,584
Ensembl chr17:14,986,814...14,988,820 		JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19751987)
(PMID:9097952)		 MGI PMID:9097952 PMID:19751987 NCBI chr 4:1,102,288...1,120,973
Ensembl chr 4:1,020,582...1,037,877 		JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29374543)
(PMID:25807535)		 Ensembl
MGI		 PMID:25807535 PMID:29374543 GO_REF:0000107 NCBI chr10:85,938,240...85,976,610
Ensembl chr10:89,477,082...89,516,874 		JBrowse link
G LOC117978823 battenin acts_upstream_of_or_within ISO (PMID:10191119), (PMID:10527801)
(PMID:10440905)
(PMID:15588329)		 MGI PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G LYSET lysosomal enzyme trafficking factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,817,605...73,819,747
Ensembl chr14:93,154,232...93,156,065 		JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:9368050)
(PMID:1113502), (PMID:4031470), (PMID:4697831), (PMID:6170520)		 MGI PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 NCBI chr 1:211,229,800...211,451,947
Ensembl chr 1:216,231,824...216,436,293 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000 		JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24423645), (PMID:35025759)
(PMID:35025759)
(PMID:26681805)		 Ensembl
MGI		 PMID:24423645 PMID:26681805 PMID:35025759 GO_REF:0000107 NCBI chr 4:120,087,477...120,137,550
Ensembl chr 4:131,391,361...131,439,590 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G MYO7A myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17712420), (PMID:19632871), (PMID:25524704), (PMID:26607664) Ensembl
MGI		 PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 GO_REF:0000107 NCBI chr17:14,772,054...14,780,398
Ensembl chr17:14,996,420...15,004,242 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221) MGI
Ensembl		 PMID:25365221 GO_REF:0000107 NCBI chr 1:126,653,794...126,689,690
Ensembl chr 1:130,300,844...130,336,311 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16542649)
(PMID:16368712)		 Ensembl
MGI		 PMID:16368712 PMID:16542649 GO_REF:0000107 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
TreeGrafter
MGI		 PMID:20920792 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095 		JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221)
(PMID:37871017)
(PMID:26284655)
(PMID:28237315), (PMID:31637311)		 MGI
Ensembl		 PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 PMID:37871017 GO_REF:0000107 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616 		JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,326,802...41,341,574
Ensembl chr  X:49,182,795...49,197,194 		JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31637311) Ensembl
MGI		 PMID:31637311 GO_REF:0000107 NCBI chr 6:41,268,169...41,320,822
Ensembl chr 6:42,574,416...42,627,031 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25066864) Ensembl
TreeGrafter
MGI		 PMID:25066864 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693 		JBrowse link
G TPCN2 two pore segment channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,139,512...64,227,913
Ensembl chr11:67,438,635...67,478,106 		JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15483130) Ensembl
MGI		 PMID:15483130 GO_REF:0000107 NCBI chr11:6,744,815...6,751,556
Ensembl chr11:6,427,522...6,434,222 		JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:19,836,707...19,846,231
Ensembl chr15:38,086,518...38,095,835 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531 		JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30061306) Ensembl
MGI		 PMID:30061306 GO_REF:0000107 NCBI chr 8:121,710,118...121,777,977
Ensembl chr 8:124,461,424...124,529,262 		JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25365221)
(PMID:37871017)		 MGI
Ensembl		 PMID:25365221 PMID:37871017 GO_REF:0000107 NCBI chr14:48,326,517...48,396,486
Ensembl chr14:67,206,236...67,273,580 		JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,157,736...28,174,906
Ensembl chr 6:28,828,298...28,847,596 		JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP3 charged multivesicular body protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:86,559,695...86,619,615
Ensembl chr2A:88,106,242...88,165,104 		JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G FNIP1 folliculin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:127,070,906...127,219,548
Ensembl chr 5:133,235,501...133,384,218 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G MYO7A myosin VIIA involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743369) Ensembl
MGI		 PMID:12743369 GO_REF:0000107 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752 		JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:11544318) MGI PMID:11544318 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068 		JBrowse link
G SRPX sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19368996) Ensembl
TreeGrafter
MGI		 PMID:19368996 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:30,598,574...30,670,464
Ensembl chr  X:38,303,313...38,378,770 		JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC117978823 battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,069,592...5,127,301
Ensembl chr 3:5,169,950...5,225,543 		JBrowse link
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:24,937,091...24,965,423
Ensembl chr2A:25,032,836...25,061,149 		JBrowse link
G LOC117978823 battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:95,505,376...95,597,792
Ensembl chr2B:213,628,997...213,721,299 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840 		JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:91,660,142...91,698,215
Ensembl chr13:110,778,119...110,815,408 		JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:181,377,018...181,384,496
Ensembl chr 1:185,661,317...185,668,066 		JBrowse link
G RAB32 RAB32, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 6:149,053,138...149,069,059 JBrowse link
G RAB32 RAB32, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:144,339,323...144,354,885 JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:28,057,077...28,061,234
Ensembl chr17:28,562,118...28,566,242 		JBrowse link
G RAB38 RAB38, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:83,121,858...83,183,698
Ensembl chr11:86,710,358...86,773,142 		JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:102,814,825...102,851,700
Ensembl chr11:106,291,348...106,326,587 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISO (PMID:21255211) UniProt PMID:21255211 NCBI chr 3:125,784,604...125,873,051 JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:181,584,814...181,611,831
Ensembl chr 1:185,867,145...185,894,691 		JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030 		JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26284655) Ensembl
MGI		 PMID:26284655 GO_REF:0000107 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616 		JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385 		JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609 		JBrowse link
G IRGM immunity related GTPase M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:146,274,097...146,329,979
Ensembl chr 5:152,278,581...152,308,182 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:6,813,498...6,825,153
Ensembl chr19:7,671,704...7,683,093 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752 		JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (PMID:36161949) MGI PMID:36161949
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:23,159,321...23,178,192
Ensembl chr  X:30,716,617...30,717,522 		JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,484,896...68,541,808
Ensembl chr 4:75,075,427...75,104,629 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030 		JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:119,831,693...119,868,132
Ensembl chr12:123,201,663...123,236,019 		JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:94,414,275...94,491,483
Ensembl chr 8:96,600,799...96,677,927 		JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609 		JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:94,414,275...94,491,483
Ensembl chr 8:96,600,799...96,677,927 		JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160154) Ensembl
MGI		 PMID:23160154 GO_REF:0000107 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16768
    cellular process 15761
      cellular component organization or biogenesis 6694
        cellular component organization 6485
          organelle organization 3626
            vacuole organization 222
              lytic vacuole organization 98
                lysosome organization + 98
paths to the root