Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:protein localization to vacuole
go back to main search page
Accession:GO:0072665 term browser browse the term
Definition:A process in which a protein is transported to, or maintained at, a location in a vacuole.
Synonyms:exact_synonym: protein localisation to vacuole


show annotations for term's descendants           Sort by:
protein localization to vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:21081491) MGI PMID:21081491 NCBI chr 2:82,188,814...82,202,019 JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO (PMID:19938078), (PMID:25505245) UniProt PMID:19938078 PMID:25505245 NCBI chr 1:167,457,067...167,524,163 JBrowse link
negative regulation of protein localization to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:24529379) UniProt PMID:24529379 NCBI chr 7:130,247,175...130,267,462 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:24305806) ARUK-UCL PMID:24305806 NCBI chr 7:36,704,377...36,798,321 JBrowse link
neurotransmitter receptor transport, postsynaptic endosome to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in ISO (PMID:24217640) SynGO PMID:24217640 NCBI chr 1:154,141,521...154,176,648 JBrowse link
positive regulation of protein localization to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO (PMID:28935770), (PMID:31001086) UniProt PMID:28935770 PMID:31001086 NCBI chr 2:100,200,259...100,205,961 JBrowse link
G Meak7 MTOR associated protein, eak-7 homolog involved_in ISO (PMID:29750193) UniProt PMID:29750193 NCBI chr17:39,405,486...39,427,647 JBrowse link
protein localization to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO (PMID:30538141) UniProt PMID:30538141 NCBI chr 1:17,139,547...17,159,056 JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:25635054) BHF-UCL PMID:25635054 NCBI chr 2:6,635,177...6,651,199 JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 acts_upstream_of_or_within ISO (PMID:25592972) MGI PMID:25592972 NCBI chr 9:68,496,532...68,514,818 JBrowse link
G Glmp glycosylated lysosomal membrane protein involved_in ISO (PMID:32959924) UniProt PMID:32959924 NCBI chr 3:65,223,151...65,226,641 JBrowse link
G Kics2 KICSTOR subunit 2 involved_in ISO (PMID:28199306) UniProt PMID:28199306 NCBI chr 1:200,172,224...200,185,703 JBrowse link
G Kptn kaptin, actin binding protein involved_in ISO (PMID:28199306) UniProt PMID:28199306 NCBI chr 2:172,950,842...172,958,781 JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 involved_in ISO (PMID:22980980) UniProt PMID:22980980 NCBI chr16:16,044,336...16,050,818 JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:22980980) UniProt PMID:22980980 NCBI chr 3:50,966,809...50,971,900 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22949502) ARUK-UCL PMID:22949502 NCBI chr 1:27,387,558...27,409,795 JBrowse link
G Lmbrd1 LMBR1 domain containing 1 involved_in ISO (PMID:27456980) UniProt PMID:27456980 NCBI chr 4:102,030,333...102,113,048 JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 involved_in ISO (PMID:32959924) UniProt PMID:32959924 NCBI chr 3:87,652,328...87,670,058 JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:38538795) UniProt PMID:38538795 NCBI chr 6:58,276,096...58,320,896 JBrowse link
G Rraga Ras related GTP binding A involved_in ISO (PMID:31601708) UniProt PMID:31601708 NCBI chr 1:67,412,997...67,414,612 JBrowse link
G Rragc Ras related GTP binding C involved_in ISO (PMID:31601708) UniProt PMID:31601708 NCBI chr 1:34,373,682...34,392,655 JBrowse link
G Rtn4 reticulon 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chr11:97,309,946...97,356,749 JBrowse link
G Sh3bp4 SH3 domain binding protein 4 involved_in ISO (PMID:22575674) UniProt PMID:22575674 NCBI chr 4:161,091,879...161,171,481 JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex involved_in ISO (PMID:28199306) UniProt PMID:28199306 NCBI chr 1:38,617,662...38,663,765 JBrowse link
protein localization to vacuolar membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (PMID:21068542) UniProt PMID:21068542 NCBI chr 3:16,006,364...16,040,244 JBrowse link
protein targeting to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:14557411) MGI PMID:14557411 NCBI chr 3:201,782,994...201,982,976 JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 involved_in ISO (PMID:11139587) UniProt PMID:11139587 NCBI chr16:15,544,477...15,552,688 JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 involved_in ISO (PMID:16885419) UniProt PMID:16885419 NCBI chr18:24,390,342...24,441,103 JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO (PMID:17116753) ARUK-UCL PMID:17116753 NCBI chr 9:68,496,532...68,514,818 JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO (PMID:18767904) UniProt PMID:18767904 NCBI chr 9:63,540,680...63,558,463 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) ARUK-UCL PMID:18619870 NCBI chr 1:27,387,558...27,409,795 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO chorionic gonadotropin after receptor internalization RGD PMID:10847593 RGD:2292601 NCBI chr 7:4,077,790...4,137,727 JBrowse link
G Lyset lysosomal enzyme trafficking factor acts_upstream_of_or_within ISO (PMID:36074821) MGI PMID:36074821 NCBI chr 7:114,017,372...114,019,170 JBrowse link
G Ncoa4 nuclear receptor coactivator 4 acts_upstream_of_or_within ISO (PMID:25327288) MGI PMID:25327288 NCBI chr13:7,845,633...7,865,914 JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:28675177) MGI PMID:28675177 NCBI chr  X:5,226,608...5,251,034 JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO (PMID:17116753) ARUK-UCL PMID:17116753 NCBI chr 8:66,997,698...67,082,612 JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:22115783) BHF-UCL PMID:22115783 NCBI chr 6:58,276,096...58,320,896 JBrowse link
G Scarb2 scavenger receptor class B member 2 involved_in ISO (PMID:18022370)
(PMID:18022370), (PMID:25316793) 		BHF-UCL
ParkinsonsUK-UCL		 PMID:18022370 PMID:25316793 NCBI chr11:5,290,883...5,345,758 JBrowse link
G Snx16 sorting nexin 16 involved_in ISO (PMID:12813048) UniProt PMID:12813048 NCBI chr 3:144,478,891...144,498,732 JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:24523320) Alzheimers_University_of_Toronto PMID:24523320 NCBI chr 8:36,555,463...36,715,316 JBrowse link
G Sort1 sortilin 1 acts_upstream_of_or_within ISO (PMID:19732768) MGI PMID:19732768 NCBI chr 3:49,898,522...49,971,954 JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:26,756,167...26,770,097 JBrowse link
G Vps53 VPS53 subunit of GARP complex involved_in ISO (PMID:28658628) MGI PMID:28658628 NCBI chr 9:94,770,190...94,892,496 JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO (PMID:28658628), (PMID:32345721) MGI PMID:28658628 PMID:32345721 NCBI chr11:89,428,683...89,504,206 JBrowse link
G Washc1 WASH complex subunit 1 involved_in ISO (PMID:20175130) UniProt PMID:20175130 NCBI chr 4:154,688,397...154,691,430 JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 involved_in ISO (PMID:11546807) UniProt PMID:11546807 NCBI chr 3:203,771,877...203,816,427 JBrowse link
protein targeting to lysosome involved in chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO (PMID:9228033) ARUK-UCL PMID:9228033 NCBI chr12:58,463,019...58,475,194 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:11559757), (PMID:36586411)
(PMID:26212789) 		UniProt
ParkinsonsUK-UCL		 PMID:11559757 PMID:26212789 PMID:36586411 NCBI chr 8:35,401,907...35,405,851 JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in
acts_upstream_of_or_within 		ISO (PMID:27628032)
PMID:18644871 		UniProt
MGI		 PMID:18644871 PMID:27628032 RGD:10412301 NCBI chr  X:101,913,626...101,950,698 JBrowse link
protein targeting to vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps54 VPS54 subunit of GARP complex involved_in ISO (PMID:23708095) MGI PMID:23708095 NCBI chr11:89,428,683...89,504,206 JBrowse link
protein targeting to vacuole involved in autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:22020285) ParkinsonsUK-UCL PMID:22020285 NCBI chr16:8,230,555...8,321,137 JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:27498865), (PMID:30612879), (PMID:32715615), (PMID:34893540), (PMID:36221902), (PMID:37802024) UniProt PMID:27498865 PMID:30612879 PMID:32715615 PMID:34893540 PMID:36221902 More... NCBI chr 9:32,865,939...32,877,232 JBrowse link
regulation of protein targeting to vacuolar membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vamp7 vesicle associated membrane protein 7 acts_upstream_of_or_within ISO (PMID:18227281) MGI PMID:18227281 NCBI chr16:15,277,986...15,303,416 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12423
    localization 4251
      macromolecule localization 2295
        intracellular protein localization 1969
          protein localization to organelle 787
            protein localization to vacuole 49
              maintenance of protein location in vacuole 0
              protein localization to lysosome + 44
              protein localization to vacuolar membrane + 2
              protein targeting to vacuole + 28
              protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 0
paths to the root