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ONTOLOGY REPORT - ANNOTATIONS

Term:reactive oxygen species metabolic process
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Accession:GO:0072593 term browser browse the term
Definition:The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Synonyms:exact_synonym: ROS metabolic process;   reactive oxygen species metabolism


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reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chr 2:72,188,562...72,191,344
Ensembl chr 2:72,188,266...72,191,326 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12855558)
(PMID:10726970), (PMID:9681465)		 Ensembl
MGI		 PMID:9681465 PMID:10726970 PMID:12855558 GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G CCN1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) MGI PMID:19364818 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G CCN2 cellular communication network factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19364818) Ensembl
MGI		 PMID:19364818 GO_REF:0000107 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20716577) Ensembl
MGI		 PMID:20716577 GO_REF:0000107 NCBI chr31:39,301,718...39,319,895
Ensembl chr31:39,301,748...39,448,062 		JBrowse link
G CYB5R4 cytochrome b5 reductase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,170,571...44,247,494
Ensembl chr12:44,141,582...44,247,493 		JBrowse link
G CYBA cytochrome b-245 alpha chain acts_upstream_of_or_within ISO (PMID:24185898) MGI PMID:24185898 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chr 4:22,916,718...22,918,893
Ensembl chr 4:22,916,096...22,964,035 		JBrowse link
G DRD5 dopamine receptor D5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,621,187...69,623,522
Ensembl chr 3:69,621,734...69,623,893 		JBrowse link
G DUOX1 dual oxidase 1 acts_upstream_of_or_within ISO (PMID:20233719) MGI PMID:20233719 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G GLS2 glutaminase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20351271) MGI
Ensembl		 PMID:20351271 GO_REF:0000107 NCBI chr10:722,105...737,857
Ensembl chr10:722,202...737,753 		JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in ISO (PMID:29899394) UniProt PMID:29899394 NCBI chr 2:72,638,657...72,642,648
Ensembl chr 2:72,638,705...72,642,648 		JBrowse link
G IL19 interleukin 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370360) Ensembl
MGI		 PMID:12370360 GO_REF:0000107 NCBI chr 7:6,000,994...6,006,959
Ensembl chr 7:6,000,907...6,006,870 		JBrowse link
G LOC119869900 small nucleolar RNA Z195/SNORD33/SNORD32 family acts_upstream_of_or_within ISO (PMID:27820699) MGI PMID:27820699
G LOC119869903 small nucleolar RNA SNORD34 acts_upstream_of_or_within ISO (PMID:27820699) MGI PMID:27820699
G LOC119869908 small nucleolar RNA SNORD35 acts_upstream_of_or_within ISO (PMID:27820699) MGI PMID:27820699
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23994610) MGI PMID:23994610 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MPV17 mitochondrial inner membrane protein MPV17 acts_upstream_of_or_within ISO (PMID:7957077) MGI PMID:7957077 NCBI chr17:21,280,523...21,290,967
Ensembl chr17:21,281,361...21,290,339 		JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:16631601) UniProt PMID:16631601 NCBI chr 6:28,385,199...28,393,560 JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 acts_upstream_of_or_within ISO (PMID:17189252) MGI PMID:17189252 NCBI chr MT:3,914...4,955
Ensembl chr MT:3,914...4,957 		JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:43,721,568...43,730,607
Ensembl chr20:43,721,640...43,730,295 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:14,680,908...14,713,838
Ensembl chr37:14,683,083...14,713,754 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,069,402...42,075,843
Ensembl chr18:42,069,398...42,076,921 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 involved_in
acts_upstream_of_or_within		 ISO (PMID:16870178)
(PMID:29501746)		 UniProt
MGI		 PMID:16870178 PMID:29501746 NCBI chr 4:61,613,580...61,727,219
Ensembl chr 4:61,613,589...61,727,205 		JBrowse link
G NNT nicotinamide nucleotide transhydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,348,222...66,437,889
Ensembl chr 4:66,349,318...66,442,841 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) UniProt PMID:17942966 MGI:5009390 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17448897) Ensembl
MGI		 PMID:17448897 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:5009394|PMID:17538188) UniProt PMID:17538188 MGI:5009394 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256 		JBrowse link
G PLA2R1 phospholipase A2 receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:5,696,733...5,793,599
Ensembl chr36:5,698,429...5,794,204 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081) UniProt PMID:14699081 NCBI chr 1:16,469,793...16,472,910
Ensembl chr 1:16,469,793...16,472,910 		JBrowse link
G PRDX4 peroxiredoxin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11229364) Ensembl
MGI		 PMID:11229364 GO_REF:0000107 NCBI chr  X:19,361,658...19,383,718
Ensembl chr  X:19,361,731...19,383,719 		JBrowse link
G PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21179475) Ensembl
MGI		 PMID:21179475 GO_REF:0000107 NCBI chr24:35,403,078...35,503,428
Ensembl chr24:35,404,564...35,582,041 		JBrowse link
G RFK riboflavin kinase acts_upstream_of_or_within ISO (PMID:19641494) MGI PMID:19641494 NCBI chr 1:82,062,290...82,071,033
Ensembl chr 1:82,059,631...82,069,257 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 acts_upstream_of ISO (PMID:19498109) MGI PMID:19498109 NCBI chr 8:4,304,167...4,309,514
Ensembl chr 8:4,305,250...4,309,325 		JBrowse link
G SESN1 sestrin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,958,995...66,057,369
Ensembl chr12:65,960,066...66,057,035 		JBrowse link
G SESN2 sestrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492 		JBrowse link
G SH3PXD2A SH3 and PX domains 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:15,936,927...16,165,537
Ensembl chr28:15,943,097...16,117,710 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G UCP2 uncoupling protein 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21178006) Ensembl
MGI		 PMID:21178006 GO_REF:0000107 NCBI chr20:53,482,239...53,532,399
Ensembl chr20:53,482,498...53,531,296 		JBrowse link
cellular detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase involved_in ISO (PMID:18379038) ComplexPortal PMID:18379038 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447 		JBrowse link
G LOC100687127 thioredoxin-like involved_in ISO (PMID:22492997) ParkinsonsUK-UCL PMID:22492997 NCBI chr  X:82,986,288...82,986,753 JBrowse link
detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:14749723) UniProt PMID:14749723 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,658,692...4,682,667
Ensembl chr 9:4,658,090...4,679,096 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISO PMID:8798532 BHF-UCL PMID:8798532 RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G CYBB cytochrome b-245 beta chain acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14980704) Ensembl
MGI		 PMID:14980704 GO_REF:0000107 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14980704) Ensembl
MGI		 PMID:14980704 GO_REF:0000107 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G DUOX1 dual oxidase 1 involved_in ISO (PMID:19339556), (PMID:22814254) UniProt PMID:19339556 PMID:22814254 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G DUOX2 dual oxidase 2 involved_in ISO (PMID:16651268), (PMID:19339556), (PMID:22814254), (PMID:25761904) UniProt PMID:16651268 PMID:19339556 PMID:22814254 PMID:25761904 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
G SOD1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:14679182)
(PMID:15544046)		 RGD
MGI
UniProt		 PMID:10640619 PMID:12514262 PMID:14679182 PMID:15544046 PMID:15880490 RGD:1581090 RGD:1601266 RGD:634854 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15642720 RGD:2291946 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G CAT catalase acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:642030)
(PMID:10617683), (PMID:17275685), (PMID:9600348)
(PMID:15178682)		 RGD
MGI
TreeGrafter
GO_Central
InterPro
UniProt		 PMID:642030 PMID:9600348 PMID:10617683 PMID:14713308 PMID:15178682 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 RGD:1358492 RGD:2292202 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447 		JBrowse link
G DUOX1 dual oxidase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10754271)
(PMID:15827346)
(PMID:10915565), (PMID:11545230), (PMID:15182862), (PMID:9788901)		 Ensembl
MGI
TreeGrafter		 PMID:9788901 PMID:10754271 PMID:10915565 PMID:11545230 PMID:15182862 More... GO_REF:0000107 GO_REF:0000118 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G GPX3 glutathione peroxidase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10617683) TreeGrafter
MGI		 PMID:10617683 GO_REF:0000118 NCBI chr 4:58,200,671...58,209,010
Ensembl chr 4:58,200,672...58,209,010 		JBrowse link
G HBE1 hemoglobin subunit epsilon 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:28,203,274...28,204,888 JBrowse link
G HBM hemoglobin subunit mu involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:40,330,773...40,331,500
Ensembl chr 6:40,330,773...40,332,207 		JBrowse link
G HBQ1 hemoglobin subunit theta 1 involved_in IEA TreeGrafter GO_REF:0000118
G LOC100855540 hemoglobin subunit alpha-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:40,324,378...40,325,427 JBrowse link
G LOC100855558 hemoglobin subunit alpha-like involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:40,328,053...40,329,002 JBrowse link
G LOC100855600 hemoglobin subunit zeta-like involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:40,331,717...40,332,764 JBrowse link
G LOC100855634 hemoglobin subunit zeta-like involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:40,342,517...40,343,540 JBrowse link
G LOC475156 peroxiredoxin 1 pseudogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:50,791,386...50,792,228 JBrowse link
G LOC476825 hemoglobin subunit beta-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:28,178,987...28,180,346 JBrowse link
G LOC480784 hemoglobin subunit beta-like involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr21:28,181,419...28,182,907 JBrowse link
G LOC485255 hemoglobin subunit epsilon-2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:28,193,163...28,194,746 JBrowse link
G LOC609402 hemoglobin subunit beta-like involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr21:28,187,535...28,188,991 JBrowse link
G LOC611135 peroxiredoxin 3 pseudogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:16,841,537...16,842,685 JBrowse link
G MPO myeloperoxidase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11907569)
(PMID:10085024)		 MGI
Ensembl		 PMID:10085024 PMID:11907569 GO_REF:0000107 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G PRDX1 peroxiredoxin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11986303) MGI
TreeGrafter		 PMID:11986303 GO_REF:0000118 NCBI chr15:14,834,009...14,855,665
Ensembl chr15:14,838,652...14,862,971 		JBrowse link
G PRDX2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15902258) Ensembl
MGI
TreeGrafter		 PMID:15902258 GO_REF:0000107 GO_REF:0000118 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682 		JBrowse link
G PRDX3 peroxiredoxin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7733872) MGI
TreeGrafter		 PMID:7733872 GO_REF:0000118 NCBI chr28:29,395,593...29,403,745
Ensembl chr28:29,395,581...29,403,745 		JBrowse link
G PRDX4 peroxiredoxin 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:19,361,658...19,383,718
Ensembl chr  X:19,361,731...19,383,719 		JBrowse link
G PRDX5 peroxiredoxin 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:52,750,977...52,754,432 JBrowse link
G PRDX6 peroxiredoxin 6 ISO RGD PMID:8641418 RGD:729495 NCBI chr 7:25,663,238...25,675,855
Ensembl chr 7:25,663,579...25,675,754 		JBrowse link
G PXDN peroxidasin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:834,625...891,551
Ensembl chr17:836,434...875,117 		JBrowse link
G TPO thyroid peroxidase involved_in IEA UniProt GO_REF:0000043 NCBI chr17:773,790...810,044
Ensembl chr17:773,790...810,043 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO RGD PMID:10849437 RGD:634378 NCBI chr10:33,904,065...34,021,549
Ensembl chr10:33,886,343...34,021,696 		JBrowse link
hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYCS cytochrome c, somatic acts_upstream_of_or_within ISO (PMID:16757556) MGI PMID:16757556 NCBI chr14:38,579,446...38,581,983
Ensembl chr14:38,579,446...38,581,983 		JBrowse link
G DUOXA1 dual oxidase maturation factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23770197) Ensembl
MGI		 PMID:23770197 GO_REF:0000107 NCBI chr30:11,546,285...11,555,715
Ensembl chr30:11,547,014...11,555,110 		JBrowse link
G DUOXA2 dual oxidase maturation factor 2 acts_upstream_of_or_within ISO (PMID:23770197) MGI PMID:23770197 NCBI chr30:11,541,849...11,546,019
Ensembl chr30:11,542,078...11,545,811 		JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:21258655 RGD:5131481 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G NOX1 NADPH oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within		 ISO (PMID:24567322)
(PMID:17766438)		 ParkinsonsUK-UCL
MGI		 PMID:17766438 PMID:24567322 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PRDX2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15259009), (PMID:17325201) Ensembl
MGI		 PMID:15259009 PMID:17325201 GO_REF:0000107 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:16716903 RGD:1580833 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
hypochlorous acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPO myeloperoxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10085024) Ensembl
MGI		 PMID:10085024 GO_REF:0000107 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter ISO RGD PMID:26482480 RGD:12910938 NCBI chr 9:47,474,488...47,490,951
Ensembl chr 9:47,473,901...47,490,252 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:21410437 RGD:7349317 NCBI chr14:38,579,446...38,581,983
Ensembl chr14:38,579,446...38,581,983 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr 6:28,385,199...28,393,560 JBrowse link
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MT-III transcription initiation factor TFIID subunit 4 ISO RGD PMID:12058024 RGD:625483 NCBI chr 2:59,624,845...59,630,386 JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11991626 RGD:10003093 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358 		JBrowse link
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in ISO PMID:31511561 UniProt PMID:31511561 RGD:126781736 NCBI chr  X:58,305,804...58,470,827
Ensembl chr  X:58,306,776...58,471,417 		JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,545,690...121,564,117
Ensembl chr  X:121,545,586...121,563,186 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:14,015,093...14,084,362
Ensembl chr27:14,015,091...14,163,312 		JBrowse link
G ADCY10 adenylate cyclase 10 ISO RGD PMID:32664470 RGD:329347825 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 ISO RGD PMID:22209705 RGD:13800744 NCBI chr 9:25,123,194...25,125,959
Ensembl chr 9:25,123,241...25,127,909 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:18292530 RGD:11341712 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095 		JBrowse link
G COA8 cytochrome c oxidase assembly factor 8 involved_in ISO (PMID:25175347) UniProt PMID:25175347 NCBI chr 8:71,324,271...71,357,468
Ensembl chr 8:71,318,244...71,357,466 		JBrowse link
G CTNS cystinosin, lysosomal cystine transporter ISO RGD PMID:26482480 RGD:12910938 NCBI chr 9:47,474,488...47,490,951
Ensembl chr 9:47,473,901...47,490,252 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:23041468 RGD:10401126 NCBI chr12:35,576,576...35,581,339
Ensembl chr12:35,576,576...35,581,230 		JBrowse link
G HBP1 HMG-box transcription factor 1 involved_in ISO (MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:5754467 NCBI chr18:13,339,359...13,368,105
Ensembl chr18:13,340,287...13,367,915 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:22547655 RGD:10402548 NCBI chr37:7,010,421...7,025,912 JBrowse link
G INS insulin involved_in ISO (PMID:19188609) ARUK-UCL PMID:19188609 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28483668 RGD:12910717 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G MIR140 microRNA mir-140 ISO RGD PMID:32519270 RGD:329347827 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR181A-1 microRNA mir-181a-1 involved_in ISO (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 7:4,055,465...4,055,526
Ensembl chr 7:4,055,465...4,055,526 		JBrowse link
G MIR181A-2 microRNA mir-181a-2 involved_in ISO (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 9:58,302,547...58,302,606
Ensembl chr 9:58,302,547...58,302,606 		JBrowse link
G MIR590 microRNA mir-590 involved_in ISO (PMID:26648441) BHF-UCL PMID:26648441 NCBI chr 6:6,186,538...6,186,598
Ensembl chr 6:6,186,538...6,186,598 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr21:20,748,452...20,758,236 JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (MGI:5908331|PMID:22611253) UniProt PMID:22611253 MGI:5908331 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G PTGR1 prostaglandin reductase 1 ISO RGD PMID:9667737 RGD:401959219 NCBI chr11:66,191,155...66,212,075
Ensembl chr11:66,191,165...66,209,219 		JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:23422569 RGD:9585767 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
negative regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATF apoptosis antagonizing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:36,773,313...36,878,752
Ensembl chr 9:36,773,312...36,878,745 		JBrowse link
G ATG5 autophagy related 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7889565) Ensembl
MGI		 PMID:7889565 GO_REF:0000107 NCBI chr26:27,856,280...27,980,923
Ensembl chr26:27,856,082...27,978,318 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr 5:29,324,893...29,343,322
Ensembl chr 5:29,325,331...29,337,240 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494 		JBrowse link
G CRYAB crystallin alpha B ISO RGD PMID:15358243 RGD:1598485 NCBI chr 5:21,181,836...21,185,164
Ensembl chr 5:21,179,936...21,360,132 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:23608653 RGD:7364951 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24190878 RGD:10449133 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,287,367...48,329,470
Ensembl chr17:48,289,272...48,348,663 		JBrowse link
G LOC119877912 beclin-1 involved_in IEA Ensembl GO_REF:0000107
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,949,631...28,957,915
Ensembl chr 5:28,949,631...28,958,222 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5050076|PMID:17357786) UniProt PMID:17357786 MGI:5050076 NCBI chr17:11,720,857...11,724,308 JBrowse link
G NOL7 nucleolar protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:13,058,894...13,063,367
Ensembl chr35:13,017,397...13,063,022 		JBrowse link
G PAX2 paired box 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G PLIN5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,181,171...55,189,369
Ensembl chr20:55,181,198...55,189,366 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
G SIRT3 sirtuin 3 ISO RGD PMID:23397292 RGD:9586042 NCBI chr18:25,369,183...25,388,126
Ensembl chr18:25,369,382...25,388,118 		JBrowse link
G SIRT5 sirtuin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:13,017,397...13,055,655
Ensembl chr35:13,017,397...13,063,022 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:20066163) UniProt PMID:20066163 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (MGI:4868339|PMID:21048113) UniProt PMID:21048113 MGI:4868339 NCBI chr21:28,677,196...28,696,413
Ensembl chr21:28,682,973...28,695,185 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924 		JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATF apoptosis antagonizing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:36,773,313...36,878,752
Ensembl chr 9:36,773,312...36,878,745 		JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO (PMID:11168643) MGI PMID:11168643 NCBI chr20:49,812,444...49,816,262
Ensembl chr20:49,814,032...49,816,260 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G CRP C-reactive protein ISO RGD PMID:9767445 RGD:9586000 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166 		JBrowse link
G PON3 paraoxonase 3 involved_in ISO (MGI:5543365|PMID:22441669) CACAO PMID:22441669 MGI:5543365 NCBI chr14:20,615,180...20,642,807
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:11,546,285...11,555,715
Ensembl chr30:11,547,014...11,555,110 		JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in ISO (PMID:16651268)
(PMID:22814254)		 UniProt PMID:16651268 PMID:22814254 NCBI chr30:11,541,849...11,546,019
Ensembl chr30:11,542,078...11,545,811 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:27279484 RGD:151347625 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G ZNF205 zinc finger protein 205 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,085,069...38,095,012
Ensembl chr 6:38,085,231...38,097,678 		JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:24722990 RGD:13513981 NCBI chr 4:66,348,222...66,437,889
Ensembl chr 4:66,349,318...66,442,841 		JBrowse link
G SNCA synuclein alpha involved_in ISO (PMID:23507046) ParkinsonsUK-UCL PMID:23507046 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:28386847 RGD:329337357 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:36,627,791...36,649,013
Ensembl chr13:36,614,498...36,690,936 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15450084 RGD:2313867 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16522634) Ensembl
MGI		 PMID:16522634 GO_REF:0000107 NCBI chr25:20,528,708...20,616,687
Ensembl chr25:20,528,699...20,615,070 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:24278276 RGD:10402204 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17308309 ARUK-UCL PMID:17308309 RGD:12910994 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:24073824 RGD:10402792 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G MIR24-1 microRNA mir-24-1 involved_in ISO (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr 1:71,677,608...71,677,669
Ensembl chr 1:71,677,608...71,677,669 		JBrowse link
G MIR24-2 microRNA mir-24-2 involved_in ISO (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr20:48,620,684...48,620,745
Ensembl chr20:48,620,674...48,620,745 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO RGD PMID:21712532 RGD:9590189 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) MGI PMID:22555455 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5300086|PMID:22041900) ARUK-UCL
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G RAB27A RAB27A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 acts_upstream_of_or_within ISO (MGI:6414721|PMID:28128227) ARUK-UCL PMID:28128227 MGI:6414721 NCBI chr31:28,610,332...28,635,233
Ensembl chr31:28,610,332...28,635,233 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
positive regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chr22:30,545,991...30,557,199
Ensembl chr22:30,547,271...30,555,510 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:19885844 RGD:7244243 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129 		JBrowse link
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) involved_in ISO (PMID:19442656) UniProt PMID:19442656 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281 		JBrowse link
G CPNE6 copine 6 involved_in ISO (PMID:19442656) UniProt PMID:19442656 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:20439821 RGD:7829726 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:289,864...291,518
Ensembl chr 9:289,889...291,480 		JBrowse link
G DUOXA1 dual oxidase maturation factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20233719) Ensembl
MGI		 PMID:20233719 GO_REF:0000107 NCBI chr30:11,546,285...11,555,715
Ensembl chr30:11,547,014...11,555,110 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A ISO RGD PMID:20930373 RGD:10395362 NCBI chr 5:32,268,103...32,272,970 JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:30574656 RGD:126781752 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G LEP leptin ISO RGD PMID:20738325 RGD:8693628 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LOC119867057 carbonyl reductase [NADPH] 1-like involved_in IEA Ensembl GO_REF:0000107
G LOC119867058 carbonyl reductase [NADPH] 1-like involved_in IEA Ensembl GO_REF:0000107
G LOC610164 carbonyl reductase [NADPH] 1 involved_in ISO (PMID:19442656) UniProt PMID:19442656 NCBI chr31:31,316,573...31,321,413 JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:16254042 RGD:1581408 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:15848200 RGD:2324674 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G NOX5 NADPH oxidase 5 involved_in ISO (PMID:17275676) UniProt PMID:17275676 NCBI chr30:32,929,287...32,985,944
Ensembl chr30:32,951,501...32,986,559 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 ISO RGD PMID:23554738 RGD:11073697 NCBI chr35:3,294,776...3,315,438
Ensembl chr35:3,294,850...3,312,836 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:20969476) ParkinsonsUK-UCL PMID:20969476 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISO (MGI:5284758|PMID:19019919) UniProt PMID:19019919 MGI:5284758 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672 		JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:16456094 RGD:6484217 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15158121 RGD:1642626 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:5315337|PMID:21052097)
(PMID:19498109)		 UniProt
MGI		 PMID:19498109 PMID:21052097 MGI:5315337 NCBI chr 8:4,304,167...4,309,514
Ensembl chr 8:4,305,250...4,309,325 		JBrowse link
G RNF41 ring finger protein 41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:512,650...521,293
Ensembl chr10:514,635...542,395 		JBrowse link
G ROMO1 reactive oxygen species modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,614,920...24,616,586
Ensembl chr24:24,615,197...24,616,582
Ensembl chr25:24,615,197...24,616,582 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TSPO translocator protein involved_in ISO
IEA		 RGD
Ensembl		 PMID:12437594 GO_REF:0000107 RGD:2317161 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371 		JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:21376054 RGD:5129173 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:21076237 RGD:5129195 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:11316806) ARUK-UCL PMID:11316806 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G B9D2 B9 domain containing 2 involved_in ISO (PMID:22073128) BHF-UCL PMID:22073128 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G CD177 CD177 molecule involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chr 1:111,693,234...111,698,879
Ensembl chr 1:111,693,005...111,698,742 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:35,896,421...35,920,649
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G CRP C-reactive protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:15036821 RGD:8693734 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:22966991 RGD:7204494 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G ELAVL1 ELAV like RNA binding protein 1 ISO RGD PMID:26682942 RGD:329961560 NCBI chr20:52,648,878...52,677,578 JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G FPR formyl peptide receptor involved_in ISO (MGI:5905278|PMID:11316806) ARUK-UCL PMID:11316806 MGI:5905278 NCBI chr 1:105,343,096...105,353,563
Ensembl chr 1:105,344,463...105,372,070 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 6:42,275,060...42,315,545
Ensembl chr 6:42,276,998...42,315,533 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009187|PMID:11408560) BHF-UCL PMID:11408560 MGI:5009187 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 ISO RGD PMID:24935944 RGD:14985214 NCBI chr26:8,437,032...8,474,831
Ensembl chr26:8,419,269...8,466,523 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:19497959 RGD:4889403 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G ITGAM integrin subunit alpha M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286 		JBrowse link
G ITGB2 integrin subunit beta 2 involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018 		JBrowse link
G MAPT microtubule associated protein tau involved_in ISO (PMID:22920254) ParkinsonsUK-UCL PMID:22920254 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:24294978 PMID:26682942 RGD:329955573 RGD:329961560 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 involved_in ISO (PMID:24141169) AgBase PMID:24141169 NCBI chr27:35,828,852...35,838,748
Ensembl chr27:35,828,029...35,838,754 		JBrowse link
G PRKCD protein kinase C delta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in ISO (PMID:18219391) UniProt PMID:18219391 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within ISO (PMID:20935152) MGI PMID:20935152 NCBI chr27:25,199,580...25,352,637
Ensembl chr27:25,200,418...25,388,477 		JBrowse link
G AHR aryl hydrocarbon receptor ISO RGD PMID:35788946 RGD:401793705 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444 		JBrowse link
G DMD dystrophin acts_upstream_of_or_within ISO (PMID:20716577) MGI PMID:20716577 NCBI chr  X:26,290,903...28,444,635
Ensembl chr  X:26,290,910...28,333,576 		JBrowse link
G GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 involved_in ISO (PMID:22573891) UniProt PMID:22573891 NCBI chr28:14,775,431...14,896,121
Ensembl chr28:14,788,369...14,895,978 		JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,264,120...2,284,196 JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:24287405) MGI PMID:24287405 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO RGD PMID:21275845 RGD:41404729 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSR insulin receptor ISO in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046 		JBrowse link
G NOXA1 NADPH oxidase activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,306,652...48,316,196
Ensembl chr 9:48,313,723...48,316,201 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G PRDX2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17325201) Ensembl
MGI		 PMID:17325201 GO_REF:0000107 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682 		JBrowse link
regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:41,588,051...41,619,406
Ensembl chr 8:41,588,150...41,619,402 		JBrowse link
G CCN6 cellular communication network factor 6 involved_in ISO (PMID:27252383) UniProt PMID:27252383 NCBI chr12:68,488,846...68,499,104
Ensembl chr12:68,478,905...68,498,049 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:8,437,032...8,474,831
Ensembl chr26:8,419,269...8,466,523 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO RGD PMID:27279484 RGD:151347625 NCBI chr 7:16,914,629...16,946,370
Ensembl chr 7:16,904,031...16,945,372 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr37:16,537,095...16,620,427
Ensembl chr37:16,541,562...16,619,554 		JBrowse link
G SLC25A33 solute carrier family 25 member 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:62,790,116...62,825,644
Ensembl chr 5:62,790,157...62,825,388 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707 		JBrowse link
G UCP1 uncoupling protein 1 involved_in IEA
ISS		 UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr19:2,254,881...2,289,902 JBrowse link
regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member ISO protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr26:9,319,109...9,361,021 JBrowse link
G ARF4 ADP ribosylation factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:32,849,725...32,871,127
Ensembl chr20:32,849,757...32,870,721 		JBrowse link
G ATG5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
G BCO2 beta-carotene oxygenase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:20,914,658...20,969,847
Ensembl chr 5:20,915,647...20,964,177 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chr 5:29,294,080...29,314,837
Ensembl chr 5:29,294,692...29,312,771 		JBrowse link
G COQ7 coenzyme Q7, hydroxylase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:25,912,936...25,922,123
Ensembl chr 6:25,912,954...25,929,655 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G EIF6 eukaryotic translation initiation factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,259,623...24,266,453
Ensembl chr24:24,259,620...24,266,255 		JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:41,894,605...41,905,656
Ensembl chr27:41,894,672...41,905,663 		JBrowse link
G FOXO1 forkhead box O1 acts_upstream_of_or_within ISO (PMID:19896444) MGI PMID:19896444 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G FOXO3 forkhead box O3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19896444) Ensembl
MGI		 PMID:19896444 GO_REF:0000107 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chr12:529,002...530,328
Ensembl chr12:529,339...530,232 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:22836756) BHF-UCL PMID:22836756 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MPV17 mitochondrial inner membrane protein MPV17 involved_in ISO (MGI:3776221|PMID:16041630) UniProt PMID:16041630 MGI:3776221 NCBI chr17:21,280,523...21,290,967
Ensembl chr17:21,281,361...21,290,339 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:19457114 RGD:5508731 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:16,790,049...16,837,557
Ensembl chr34:16,781,139...16,837,545 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:19,994,383...20,058,979
Ensembl chr  X:19,994,393...20,058,485 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G PRCP prolylcarboxypeptidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21297000) Ensembl
MGI		 PMID:21297000 GO_REF:0000107 NCBI chr21:16,219,688...16,285,186
Ensembl chr21:16,219,831...16,285,188 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:20,883,128...20,912,318
Ensembl chr 5:20,896,236...20,912,297 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chr 8:4,304,167...4,309,514
Ensembl chr 8:4,305,250...4,309,325 		JBrowse link
G RNF41 ring finger protein 41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:512,650...521,293
Ensembl chr10:514,635...542,395 		JBrowse link
G SNCA synuclein alpha involved_in ISO (MGI:5585658|PMID:25043722) ParkinsonsUK-UCL PMID:25043722 MGI:5585658 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
G STK17A serine/threonine kinase 17a involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,588,821...6,626,236
Ensembl chr18:6,590,105...6,626,245 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TUSC2 tumor suppressor 2, mitochondrial calcium regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513871) Ensembl
MGI		 PMID:22513871 GO_REF:0000107 NCBI chr20:39,024,814...39,026,209 JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G DHFR dihydrofolate reductase involved_in ISO (MGI:5645206|PMID:19666465) BHF-UCL PMID:19666465 MGI:5645206 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G FBLN5 fibulin 5 involved_in ISO (MGI:3610795|PMID:15528465) BHF-UCL PMID:15528465 MGI:3610795 NCBI chr 8:1,162,203...1,231,809
Ensembl chr 8:1,162,923...1,231,719 		JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR27B microRNA mir-27b involved_in ISO (PMID:24177325) BHF-UCL PMID:24177325 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191 		JBrowse link
G SHC1 SHC adaptor protein 1 involved_in ISO (PMID:24177325) BHF-UCL PMID:24177325 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (PMID:16371425) MGI PMID:16371425 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G CYGB cytoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,191,114...4,201,438
Ensembl chr 9:4,184,959...4,200,164 		JBrowse link
G FANCC FA complementation group C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11493445) Ensembl
MGI		 PMID:11493445 GO_REF:0000107 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506 		JBrowse link
G LOC475156 peroxiredoxin 1 pseudogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:50,791,386...50,792,228 JBrowse link
G MB myoglobin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:28,573,819...28,583,526
Ensembl chr10:28,552,749...28,583,522 		JBrowse link
G MPO myeloperoxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10085024) Ensembl
MGI		 PMID:10085024 GO_REF:0000107 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT3 metallothionein 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G NOS3 nitric oxide synthase 3 involved_in ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G PRDX1 peroxiredoxin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16170382)
(PMID:16880205)		 TreeGrafter
MGI		 PMID:16170382 PMID:16880205 GO_REF:0000118 NCBI chr15:14,834,009...14,855,665
Ensembl chr15:14,838,652...14,862,971 		JBrowse link
G PRDX2 peroxiredoxin 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
ISS		 (PMID:10679476)
(PMID:10436316), (PMID:10471451), (PMID:11493445), (PMID:8673102)
(PMID:11493445)
(PMID:9516486), (PMID:9788901)
(PMID:12433839), (PMID:17448893)		 RGD
GO_Central
MGI
GOC
UniProt		 PMID:8673102 PMID:9516486 PMID:9788901 PMID:10436316 PMID:10471451 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000108 RGD:1601266 RGD:634854 RGD:8655968 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16873728) RGD
MGI
Ensembl
GOC		 PMID:12107766 PMID:15642720 PMID:16873728 PMID:19439219 GO_REF:0000107 GO_REF:0000108 RGD:2291939 RGD:2291946 RGD:2317387 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SOD3 superoxide dismutase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455 		JBrowse link
superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP5 acid phosphatase 5, tartrate resistant acts_upstream_of ISO (PMID:11168643) MGI PMID:11168643 NCBI chr20:49,812,444...49,816,262
Ensembl chr20:49,814,032...49,816,260 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISO PMID:8798532
(PMID:2243141)		 BHF-UCL PMID:2243141 PMID:8798532 RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G CYBB cytochrome b-245 beta chain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G DUOX1 dual oxidase 1 involved_in NAS
IEA
IBA		 (PMID:10806195) UniProt
TreeGrafter
GO_Central		 PMID:10806195 GO_REF:0000033 GO_REF:0000118 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G DUOX2 dual oxidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:16788136 RGD:4892602 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within_positive_effect
involved_in		 ISO
IEA		 (PMID:2547247)
(PMID:10725280), (PMID:11156938)		 GO_Central
MGI
TreeGrafter
Ensembl		 PMID:2547247 PMID:10725280 PMID:11156938 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490028) Ensembl
MGI
TreeGrafter		 PMID:9490028 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:16,914,629...16,946,370
Ensembl chr 7:16,904,031...16,945,372 		JBrowse link
G NCF4 neutrophil cytosolic factor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:27,597,296...27,672,199
Ensembl chr10:27,597,486...27,615,261 		JBrowse link
G NOX1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18397177) Ensembl
MGI
TreeGrafter		 PMID:18397177 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G NOX3 NADPH oxidase 3 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:45,129,112...45,186,510
Ensembl chr 1:45,128,958...45,186,510 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G NOX5 NADPH oxidase 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:32,929,287...32,985,944
Ensembl chr30:32,951,501...32,986,559 		JBrowse link
G NOXA1 NADPH oxidase activator 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:48,306,652...48,316,196
Ensembl chr 9:48,313,723...48,316,201 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,951,926...38,956,134
Ensembl chr 6:38,953,741...38,956,115 		JBrowse link
G PRG3 proteoglycan 3, pro eosinophil major basic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:38,765,682...38,769,711
Ensembl chr18:38,766,095...38,769,711 		JBrowse link
G SH3PXD2A SH3 and PX domains 2A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:15,936,927...16,165,537
Ensembl chr28:15,943,097...16,117,710 		JBrowse link
G SH3PXD2B SH3 and PX domains 2B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:39,854,213...39,950,704
Ensembl chr 4:39,854,211...39,949,958 		JBrowse link
G SOD1 superoxide dismutase 1 acts_upstream_of_or_within ISO (PMID:15317809) MGI PMID:15317809 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (PMID:15781740)
(PMID:10212301)
(PMID:16677818)		 MGI PMID:10212301 PMID:15781740 PMID:16677818 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SPESP1 sperm equatorial segment protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:32,900,322...32,904,206
Ensembl chr30:32,900,750...32,902,581 		JBrowse link
G TAFA4 TAFA chemokine like family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:22,843,151...22,963,722
Ensembl chr20:22,837,094...22,962,831 		JBrowse link
superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10953023) Ensembl
MGI		 PMID:10953023 GO_REF:0000107 NCBI chr31:37,230,900...37,247,170 JBrowse link
G CCS copper chaperone for superoxide dismutase involved_in IEA InterPro GO_REF:0000002 NCBI chr18:50,748,039...50,759,270
Ensembl chr18:50,748,041...50,759,191 		JBrowse link
G CYB5R4 cytochrome b5 reductase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:44,170,571...44,247,494
Ensembl chr12:44,141,582...44,247,493 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISO (PMID:1763037), (PMID:2243141)
PMID:8798532		 RGD
BHF-UCL		 PMID:1763037 PMID:2243141 PMID:8798532 PMID:15322091 RGD:1580287 RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G CYBB cytochrome b-245 beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO (PMID:21824519) MGI PMID:21824519 NCBI chr14:50,487,679...51,336,906 JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19409882) Ensembl
MGI		 PMID:19409882 GO_REF:0000107 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:12933833) UniProt
MGI
Ensembl		 PMID:12933833 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15322091 GO_REF:0000107 RGD:1580287 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G NOXA1 NADPH oxidase activator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12473664) Ensembl
MGI		 PMID:12473664 GO_REF:0000107 NCBI chr 9:48,306,652...48,316,196
Ensembl chr 9:48,313,723...48,316,201 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 acts_upstream_of_or_within ISO (PMID:12473664) MGI PMID:12473664 NCBI chr 6:38,951,926...38,956,134
Ensembl chr 6:38,953,741...38,956,115 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:17901563 RGD:5133248 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G NRROS negative regulator of reactive oxygen species NOT|involved_in ISO
IEA		 (MGI:6192878|PMID:29909984) UniProt
Ensembl		 PMID:29909984 GO_REF:0000107 MGI:6192878 NCBI chr33:29,682,182...29,699,469
Ensembl chr33:29,692,371...29,767,771 		JBrowse link
G SH3PXD2A SH3 and PX domains 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:15,936,927...16,165,537
Ensembl chr28:15,943,097...16,117,710 		JBrowse link
G SH3PXD2B SH3 and PX domains 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:39,854,213...39,950,704
Ensembl chr 4:39,854,211...39,949,958 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,898,274...92,978,260
Ensembl chr 1:92,898,274...92,978,260 		JBrowse link
G SOD1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11404260) RGD
MGI
InterPro		 PMID:10640619 PMID:11404260 PMID:12514262 GO_REF:0000002 RGD:1601266 RGD:634854 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15637112)
(PMID:12176043)
(PMID:10049502)		 InterPro
MGI
Ensembl		 PMID:10049502 PMID:12176043 PMID:15637112 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SOD3 superoxide dismutase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular metabolic process 9218
        reactive oxygen species metabolic process 277
          hydrogen peroxide metabolic process + 59
          hypochlorous acid metabolic process + 1
          negative regulation of reactive oxygen species metabolic process + 64
          positive regulation of reactive oxygen species metabolic process + 88
          reactive oxygen species biosynthetic process + 77
          regulation of reactive oxygen species metabolic process + 184
          superoxide metabolic process + 79
paths to the root