Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:clathrin-dependent endocytosis
go back to main search page
Accession:GO:0072583 term browser browse the term
Definition:An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
Synonyms:exact_synonym: CME;   clathrin coated pit-dependent endocytosis;   clathrin-mediated endocytosis



show annotations for term's descendants           Sort by:
 
clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 involved_in ISO
IBA
(PMID:22262466), (PMID:23676497)
(MGI:5514106|PMID:23676497)
PMID:21873635
RGD PMID:22262466 PMID:23676497 PMID:21873635 MGI:5514106, RGD:13792537 NCBI chr 1:95,384,303...95,414,249
Ensembl chr 1:95,384,309...95,414,147
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000107
(MGI:5514106|PMID:23676497)
GO_REF:0000002
(PMID:22262466), (PMID:23676497)
PMID:21873635
UniProt
Ensembl
RGD
InterPro
PMID:22262466 PMID:23676497 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:5514106, RGD:13792537 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 involved_in ISO (PMID:23676497)
(MGI:5514106|PMID:23676497)
RGD PMID:23676497 MGI:5514106 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 involved_in IBA
ISO
PMID:21873635
(MGI:5514106|PMID:23676497)
(PMID:23676497), (PMID:31104773)
RGD PMID:23676497 PMID:31104773 PMID:21873635 MGI:5514106, RGD:13792537 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
JBrowse link
G Canx calnexin involved_in ISS
ISO
GO_REF:0000024
(MGI:5288282|PMID:21747946)
UniProt
RGD
PMID:21747946 GO_REF:0000024 MGI:5288282 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Clta clathrin, light chain A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
JBrowse link
G Cltb clathrin, light chain B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Cltc clathrin heavy chain involved_in ISO
IEA
(PMID:26005850)
GO_REF:0000107
RGD
Ensembl
PMID:26005850 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IDA PMID:22658936 UniProt PMID:22658936 RGD:10402035 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in IBA
ISO
PMID:21873635
(PMID:20448150), (PMID:32098969)
RGD PMID:20448150 PMID:32098969 PMID:21873635 RGD:13792537 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
JBrowse link
G Fcho2 FCH and mu domain containing endocytic adaptor 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20448150), (PMID:21762413)
UniProt
RGD
PMID:20448150 PMID:21762413 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:30,079,143...30,181,639
Ensembl chr 2:30,080,962...30,181,241
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 involved_in ISO (PMID:29887380) RGD PMID:29887380 NCBI chr 1:155,444,471...155,685,539
Ensembl chr 1:155,444,460...155,685,539
JBrowse link
G Fnbp1l formin binding protein 1-like involved_in ISO (PMID:20730103) RGD PMID:20730103 NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455
JBrowse link
G Gak cyclin G associated kinase involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:16155256)
MGI:5305733 (MGI:4439191|PMID:20160091), (MGI:5305417|PMID:18434600)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:16155256 PMID:18434600 PMID:20160091 PMID:21873635 GO_REF:0000107 MGI:4439191 MGI:5305417, RGD:13792537 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
JBrowse link
G Gpr107 G protein-coupled receptor 107 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5604949|PMID:24849652)
RGD PMID:24849652 PMID:21873635 MGI:5604949, RGD:13792537 NCBI chr 3:14,431,704...14,497,623
Ensembl chr 3:14,434,723...14,495,958
JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO (MGI:5763358|PMID:25869668) RGD PMID:25869668 MGI:5763358 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
JBrowse link
G Lmbrd1 LMBR1 domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5543853|PMID:24078630)
UniProt
RGD
PMID:24078630 GO_REF:0000024 MGI:5543853 NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090
JBrowse link
G P2rx4 purinergic receptor P2X 4 enables IMP RGD PMID:16282518 RGD:1642691 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISS
IBA
ISO
IEA
GO_REF:0000024
PMID:21873635
(MGI:5432454|PMID:22539346)
GO_REF:0000107
(PMID:22952941), (PMID:24577224), (PMID:26005850)
Alzheimers_University_of_Toronto
RGD
Ensembl
PMID:22539346 PMID:22952941 PMID:24577224 PMID:26005850 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5432454, RGD:13792537 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 5:117,536,752...117,734,593
Ensembl chr 5:117,537,746...117,734,575
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 involved_in ISO (PMID:21359217) RGD PMID:21359217 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
G Slc9b2 solute carrier family 9 member B2 involved_in ISO (MGI:5492253|PMID:23720317) RGD PMID:23720317 MGI:5492253 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Snap91 synaptosome associated protein 91 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367
JBrowse link
clathrin-dependent endocytosis of virus by host cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Siglec1 sialic acid binding Ig like lectin 1 involved_in IBA
ISO
PMID:21873635
(PMID:12857889)
RGD PMID:12857889 PMID:21873635 RGD:13792537 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
clathrin-dependent extracellular exosome endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga4 integrin subunit alpha 4 IMP RGD PMID:20124479 RGD:9698434 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
JBrowse link
clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd8 BTB domain containing 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6104538|PMID:29262337)
GO_REF:0000002
UniProt
RGD
InterPro
PMID:29262337 GO_REF:0000002 GO_REF:0000024 MGI:6104538 NCBI chr14:2,265,189...2,338,426
Ensembl chr14:2,266,454...2,334,393
JBrowse link
G Itsn1 intersectin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
JBrowse link
G Itsn2 intersectin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neu3 neuraminidase 3 involved_in ISO (PMID:26251452) RGD PMID:26251452 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 IMP RGD PMID:15066995 RGD:13504745 NCBI chr 1:136,124,502...136,255,669
Ensembl chr 1:136,124,499...136,255,584
JBrowse link
G Syt11 synaptotagmin 11 involved_in IMP PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505
JBrowse link
G Unc119 unc-119 lipid binding chaperone involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5559669|PMID:19781630)
PMID:21873635
UniProt
RGD
PMID:19781630 PMID:21873635 GO_REF:0000024 MGI:5559669, RGD:13792537 NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339
JBrowse link
positive regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5442508|PMID:16984970)
Ensembl
RGD
PMID:16984970 GO_REF:0000107 MGI:5442508 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dgkd diacylglycerol kinase, delta involved_in ISO (PMID:17880279) RGD PMID:17880279 NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:11925437 RGD:728683 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305
JBrowse link
G Wasl WASP like actin nucleation promoting factor involved_in IDA PMID:20730103 BHF-UCL PMID:20730103 RGD:8554834 NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022
JBrowse link
regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aak1 AP2 associated kinase 1 involved_in IBA
IEA
IDA
ISO
PMID:21873635
GO_REF:0000107
PMID:11877461
(PMID:17494869), (PMID:18657069)
Ensembl
RGD
PMID:17494869 PMID:18657069 PMID:21873635 PMID:11877461 GO_REF:0000107, RGD:13792537, RGD:8553925 NCBI chr 4:119,300,128...119,451,834
Ensembl chr 4:119,295,257...119,450,969
JBrowse link
G Bmp2k BMP-2 inducible kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 acts_upstream_of_or_within ISO MGI:4440489 (MGI:4439191|PMID:20160091) RGD PMID:20160091 MGI:4439191 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Prom2 prominin 2 NOT|involved_in ISO (PMID:23583380) RGD PMID:23583380 NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787
JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 IMP RGD PMID:15066995 RGD:13504745 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 IMP RGD PMID:15066995 RGD:13504745 NCBI chr 1:136,124,502...136,255,669
Ensembl chr 1:136,124,499...136,255,584
JBrowse link
G Smap1 small ArfGAP 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3581491|PMID:15659652)
RGD PMID:15659652 PMID:21873635 MGI:3581491, RGD:13792537 NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:26,249,978...26,342,170
JBrowse link
G Snap91 synaptosome associated protein 91 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16254249)
GO_REF:0000107
RGD
Ensembl
PMID:16254249 GO_REF:0000107 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367
JBrowse link
G Tnk2 tyrosine kinase, non-receptor, 2 involved_in ISO (PMID:18262180) RGD PMID:18262180 NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      vesicle-mediated transport 1677
        endocytosis 691
          receptor-mediated endocytosis 260
            clathrin-dependent endocytosis 47
              cargo loading involved in clathrin-dependent endocytosis 0
              clathrin coat assembly involved in endocytosis 0
              clathrin-dependent endocytosis involved in vitellogenesis 0
              clathrin-dependent endocytosis of virus by host cell 1
              clathrin-dependent extracellular exosome endocytosis 1
              clathrin-dependent synaptic vesicle endocytosis 3
              negative regulation of clathrin-dependent endocytosis 5
              nucleation of clathrin-coated pit 0
              positive regulation of clathrin-dependent endocytosis 5
              regulation of clathrin-dependent endocytosis + 19
              vesicle scission involved in clathrin-mediated endocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      establishment of localization 4887
        transport 4725
          vesicle-mediated transport 1677
            endocytosis 691
              receptor-mediated endocytosis 260
                clathrin-dependent endocytosis 47
                  cargo loading involved in clathrin-dependent endocytosis 0
                  clathrin coat assembly involved in endocytosis 0
                  clathrin-dependent endocytosis involved in vitellogenesis 0
                  clathrin-dependent endocytosis of virus by host cell 1
                  clathrin-dependent extracellular exosome endocytosis 1
                  clathrin-dependent synaptic vesicle endocytosis 3
                  negative regulation of clathrin-dependent endocytosis 5
                  nucleation of clathrin-coated pit 0
                  positive regulation of clathrin-dependent endocytosis 5
                  regulation of clathrin-dependent endocytosis + 19
                  vesicle scission involved in clathrin-mediated endocytosis 0
paths to the root