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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter-gated ion channel clustering
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Accession:GO:0072578 term browser browse the term
Definition:The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.


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neurotransmitter-gated ion channel clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRTM4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chr 2:76,747,685...77,522,376
Ensembl chr 2:76,747,685...77,593,319 		JBrowse link
G NLGN2 neuroligin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29107521) Ensembl
MGI		 PMID:29107521 GO_REF:0000107 NCBI chr17:7,404,653...7,419,860
Ensembl chr17:7,404,874...7,419,860 		JBrowse link
G SLITRK3 SLIT and NTRK like family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29107521) Ensembl
MGI		 PMID:29107521 GO_REF:0000107 NCBI chr 3:165,186,720...165,197,109
Ensembl chr 3:165,186,720...165,197,109 		JBrowse link
AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within_positive_effect IDA (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CHRDL1 chordin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:110,673,856...110,795,817
Ensembl chr  X:110,673,856...110,795,819 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 involved_in TAS
IBA
ISS		 (PMID:19914352) BHF-UCL
GO_Central		 PMID:19914352 GO_REF:0000024 GO_REF:0000033 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,836 		JBrowse link
G LRRTM4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chr 2:76,747,685...77,522,376
Ensembl chr 2:76,747,685...77,593,319 		JBrowse link
G NLGN1 neuroligin 1 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:173,395,952...174,294,372
Ensembl chr 3:173,396,284...174,294,372 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,408...50,733,212 		JBrowse link
gamma-aminobutyric acid receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRB glycine receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19723286) Ensembl
MGI		 PMID:19723286 GO_REF:0000107 NCBI chr 4:157,076,150...157,172,090
Ensembl chr 4:157,076,125...157,172,090 		JBrowse link
G GPHN gephyrin involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA
IDA		 (PMID:25025157)
(PMID:19723286)
(PMID:26613940)		 UniProt
MGI
GO_Central		 PMID:19723286 PMID:25025157 PMID:26613940 GO_REF:0000033 NCBI chr14:66,508,147...67,735,355
Ensembl chr14:66,507,407...67,181,803 		JBrowse link
G LHFPL4 LHFPL tetraspan subfamily member 4 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:9,498,361...9,553,822
Ensembl chr 3:9,498,361...9,553,822 		JBrowse link
G NRXN1 neurexin 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575 		JBrowse link
G SHISA7 shisa family member 7 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:55,428,740...55,443,300
Ensembl chr19:55,428,740...55,443,300 		JBrowse link
glycine receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPHN gephyrin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:9812897) MGI
GO_Central		 PMID:9812897 GO_REF:0000033 NCBI chr14:66,508,147...67,735,355
Ensembl chr14:66,507,407...67,181,803 		JBrowse link
NMDA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within_positive_effect IDA (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO RGD PMID:18442977 RGD:7241017 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G NLGN1 neuroligin 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 3:173,395,952...174,294,372
Ensembl chr 3:173,396,284...174,294,372 		JBrowse link
G NRXN1 neurexin 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575 		JBrowse link
G RELN reelin involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,408...50,733,212 		JBrowse link
positive regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLG4 discs large MAGUK scaffold protein 4 involved_in ISO PMID:19596852 UniProt PMID:19596852 RGD:21201259 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,836 		JBrowse link
G GRIP2 glutamate receptor interacting protein 2 involved_in ISO PMID:20083202 UniProt PMID:20083202 RGD:4107359 NCBI chr 3:14,489,107...14,603,017
Ensembl chr 3:14,489,107...14,556,075 		JBrowse link
G SNX27 sorting nexin 27 ISO RGD PMID:25071192 RGD:13508620 NCBI chr 1:151,612,050...151,699,080
Ensembl chr 1:151,612,006...151,699,091 		JBrowse link
G SSH1 slingshot protein phosphatase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20442266 GO_REF:0000107 RGD:11535133 NCBI chr12:108,778,191...108,857,583
Ensembl chr12:108,778,191...108,857,590 		JBrowse link
G ZDHHC2 zinc finger DHHC-type palmitoyltransferase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:17,156,482...17,224,799
Ensembl chr 8:17,156,482...17,224,799 		JBrowse link
regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FRRS1L ferric chelate reductase 1 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29276473) Ensembl
MGI		 PMID:29276473 GO_REF:0000107 NCBI chr 9:109,130,293...109,167,249
Ensembl chr 9:109,130,293...109,167,249 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21558424) Ensembl
MGI		 PMID:21558424 GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,408...50,733,212 		JBrowse link
G SHISA6 shisa family member 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:11,241,213...11,564,063
Ensembl chr17:11,241,213...11,564,063 		JBrowse link
G SHISA7 shisa family member 7 NOT|involved_in ISS
ISO		 (PMID:29199957) UniProt
UniProt		 PMID:29199957 GO_REF:0000024 NCBI chr19:55,428,740...55,443,300
Ensembl chr19:55,428,740...55,443,300 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25429150) Ensembl
MGI		 PMID:25429150 GO_REF:0000107 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27213
    localization 5980
      cellular localization 3945
        localization within membrane 894
          protein localization to membrane 789
            receptor clustering 81
              neurotransmitter-gated ion channel clustering 22
                NMDA glutamate receptor clustering 6
                gamma-aminobutyric acid receptor clustering 5
                glutamate receptor clustering + 14
                glycine receptor clustering 1
Path 2
Term Annotations click to browse term
  biological_process 27213
    localization 5980
      macromolecule localization 3454
        cellular macromolecule localization 2960
          protein localization 2947
            protein localization to membrane 789
              receptor clustering 81
                neurotransmitter-gated ion channel clustering 22
                  NMDA glutamate receptor clustering 6
                  gamma-aminobutyric acid receptor clustering 5
                  glutamate receptor clustering + 14
                  glycine receptor clustering 1
paths to the root