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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter-gated ion channel clustering
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Accession:GO:0072578 term browser browse the term
Definition:The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.

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neurotransmitter-gated ion channel clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRTM4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chr14:29,751,187...30,505,542 JBrowse link
G NLGN2 neuroligin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:6,781,510...6,796,304
Ensembl chr16:6,784,642...6,794,419 		JBrowse link
G SLITRK3 SLIT and NTRK like family member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:24,361,523...24,374,865
Ensembl chr15:24,367,287...24,370,226 		JBrowse link
AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within_positive_effect IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G CHRDL1 chordin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:98,490,291...98,611,811
Ensembl chr  X:98,489,874...98,611,951 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:6,562,953...6,592,247
Ensembl chr16:6,562,691...6,590,867 		JBrowse link
G LRRTM4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chr14:29,751,187...30,505,542 JBrowse link
G NLGN1 neuroligin 1 involved_in ISO PMID:21940442
(PMID:21940442)
(PMID:12796785)		 BHF-UCL
CACAO		 PMID:12796785 PMID:21940442 RGD:8553843 NCBI chr15:15,129,976...16,017,107 JBrowse link
G NLGN1 neuroligin 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:15,131,866...15,141,276 JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:33,155,695...33,209,679
Ensembl chr19:33,155,770...33,208,224 		JBrowse link
gamma-aminobutyric acid receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRB glycine receptor beta acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:103,669,663...103,760,005
Ensembl chr 7:103,669,616...103,760,531 		JBrowse link
G GPHN gephyrin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19723286) MGI
Ensembl
TreeGrafter		 PMID:19723286 GO_REF:0000107 GO_REF:0000118 NCBI chr24:43,702,384...44,421,890
Ensembl chr24:43,880,344...44,422,276 		JBrowse link
G LHFPL4 LHFPL tetraspan subfamily member 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:45,502,763...45,556,828 JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:15620359) BHF-UCL PMID:15620359 NCBI chr14:56,051,849...57,202,334 JBrowse link
G SHISA7 shisa family member 7 involved_in ISO (PMID:31601770) UniProt PMID:31601770 NCBI chr 6:48,028,539...48,049,478 JBrowse link
glycine receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPHN gephyrin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9812897) MGI
TreeGrafter		 PMID:9812897 GO_REF:0000118 NCBI chr24:43,702,384...44,421,890
Ensembl chr24:43,880,344...44,422,276 		JBrowse link
NMDA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within_positive_effect IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO RGD PMID:18442977 RGD:7241017 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G NLGN1 neuroligin 1 involved_in ISO PMID:19450252
(PMID:23143522)		 BHF-UCL PMID:19450252 PMID:23143522 RGD:8553605 NCBI chr15:15,129,976...16,017,107 JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:15620359) BHF-UCL PMID:15620359 NCBI chr14:56,051,849...57,202,334 JBrowse link
G RELN reelin involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:72,440,988...72,951,173
Ensembl chr21:72,440,160...72,950,747 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:33,155,695...33,209,679
Ensembl chr19:33,155,770...33,208,224 		JBrowse link
positive regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLG4 discs large MAGUK scaffold protein 4 involved_in ISO PMID:19596852 UniProt PMID:19596852 RGD:21201259 NCBI chr16:6,562,953...6,592,247
Ensembl chr16:6,562,691...6,590,867 		JBrowse link
G GRIP2 glutamate receptor interacting protein 2 involved_in ISO PMID:20083202 UniProt PMID:20083202 RGD:4107359 NCBI chr22:50,429,351...50,546,403
Ensembl chr22:50,433,405...50,468,769 		JBrowse link
G SNX27 sorting nexin 27 ISO RGD PMID:25071192 RGD:13508620 NCBI chr20:11,997,768...12,083,929
Ensembl chr20:11,998,527...12,083,528 		JBrowse link
G SSH1 slingshot protein phosphatase 1 ISO RGD PMID:20442266 RGD:11535133 NCBI chr11:103,982,889...104,059,673 JBrowse link
G ZDHHC2 zDHHC palmitoyltransferase 2 involved_in ISO PMID:19596852 UniProt PMID:19596852 RGD:21201259 NCBI chr 8:15,241,100...15,311,431
Ensembl chr 8:15,270,598...15,303,323 		JBrowse link
regulation of AMPA glutamate receptor clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FRRS1L ferric chelate reductase 1 like acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:30,385,877...30,416,302
Ensembl chr12:30,385,878...30,416,088 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:33,155,695...33,209,679
Ensembl chr19:33,155,770...33,208,224 		JBrowse link
G SHISA6 shisa family member 6 involved_in ISO (PMID:26931375) UniProt PMID:26931375 NCBI chr16:10,584,375...10,913,012 JBrowse link
G SHISA7 shisa family member 7 NOT|involved_in ISO (PMID:31601770)
(PMID:29199957)		 UniProt PMID:29199957 PMID:31601770 NCBI chr 6:48,028,539...48,049,478 JBrowse link
G SLC7A11 solute carrier family 7 member 11 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:85,149,810...85,225,061
Ensembl chr 7:85,154,068...85,225,144 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    localization 5964
      cellular localization 4121
        localization within membrane 1312
          protein localization to membrane 1218
            receptor clustering 87
              neurotransmitter-gated ion channel clustering 23
                NMDA glutamate receptor clustering 6
                gamma-aminobutyric acid receptor clustering 5
                glutamate receptor clustering + 15
                glycine receptor clustering 1
Path 2
Term Annotations click to browse term
  biological_process 19829
    localization 5964
      macromolecule localization 3559
        cellular macromolecule localization 3151
          protein localization 3139
            protein localization to membrane 1218
              receptor clustering 87
                neurotransmitter-gated ion channel clustering 23
                  NMDA glutamate receptor clustering 6
                  gamma-aminobutyric acid receptor clustering 5
                  glutamate receptor clustering + 15
                  glycine receptor clustering 1
paths to the root