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ONTOLOGY REPORT - ANNOTATIONS

Term:IPAF inflammasome complex
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Accession:GO:0072557 term browser browse the term
Definition:An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.


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IPAF inflammasome complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 part_of IEA
ISS
ISO
IBA		 GO_REF:0000107
GO_REF:0000024
(MGI:5289703|PMID:21874021)
GO_REF:0000118
GO_REF:0000033		 Ensembl
UniProt
RGD
TreeGrafter
GO_Central		 PMID:21874021 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5289703 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp4 caspase 4 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Naip5 NLR family, apoptosis inhibitory protein 5 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 2:31,557,706...31,608,722
Ensembl chr 2:31,557,817...31,608,634 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 part_of ISO
IBA		 (MGI:5289703|PMID:21874021)
GO_REF:0000033		 RGD
GO_Central		 PMID:21874021 GO_REF:0000033 MGI:5289703 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 part_of ISS
ISO		 GO_REF:0000024
(MGI:5289703|PMID:21874021), (MGI:5444805|PMID:22885697)		 UniProt
RGD		 PMID:21874021 PMID:22885697 GO_REF:0000024 MGI:5289703 MGI:5444805 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      canonical inflammasome complex 29
        IPAF inflammasome complex 6
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      intracellular anatomical structure 15673
        cytoplasm 12359
          cytosol 4577
            canonical inflammasome complex 29
              IPAF inflammasome complex 6
paths to the root