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ONTOLOGY REPORT - ANNOTATIONS


Term:fibroblast activation
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Accession:GO:0072537 term browser browse the term
Definition:A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.



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fibroblast activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO
IEA
(PMID:21145111)
GO_REF:0000107
RGD
Ensembl
PMID:21145111 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17ra interleukin 17 receptor A involved_in ISO (PMID:21145111) RGD PMID:21145111 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP TGFb1 RGD PMID:28100501 RGD:152995503 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Rgcc regulator of cell cycle involved_in ISS
ISO
GO_REF:0000024
(MGI:5317995|PMID:21990365)
UniProt
RGD
PMID:21990365 GO_REF:0000024 MGI:5317995 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO (PMID:28877478) RGD PMID:28877478 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IDA RGD PMID:30336567 RGD:155882532 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
hepatic stellate cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap12 A-kinase anchoring protein 12 IEP RGD PMID:23925424 RGD:14348971 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit IEP RGD PMID:22942279 RGD:11049542 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:28061416 RGD:13792735 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP RGD PMID:16936262 RGD:9743846 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Myocd myocardin IMP RGD PMID:19793196 RGD:5132876 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
negative regulation of hepatic stellate cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cygb cytoglobin IDA RGD PMID:16581302 RGD:9685176 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit IMP RGD PMID:22942279 RGD:11049542 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Mir30a microRNA 30a IDA RGD PMID:29587268 RGD:35673290 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
positive regulation of hepatic stellate cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle IMP RGD PMID:24204762 RGD:12879446 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:23409069 RGD:150517731 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18000880 RGD:10400849 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IMP RGD PMID:30250515 RGD:25330356 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Lep leptin IDA RGD PMID:19299451 RGD:5128574 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Myb MYB proto-oncogene, transcription factor IMP RGD PMID:10666057 RGD:11532677 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Pdgfb platelet derived growth factor subunit B IMP RGD PMID:15358192 RGD:10449487 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IMP RGD PMID:18466260 RGD:10449503 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:10679322)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10679322 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
JBrowse link
G Smo smoothened, frizzled class receptor IMP RGD PMID:22994359 RGD:150521663 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
regulation of hepatic stellate cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 IDA RGD PMID:24497272 RGD:10448995 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    multicellular organismal process 9322
      cell activation 1199
        fibroblast activation 25
          hepatic stellate cell activation + 19
paths to the root