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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrimidine-containing compound catabolic process
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Accession:GO:0072529 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
Synonyms:exact_synonym: pyrimidine and derivative catabolic process;   pyrimidine-containing compound breakdown;   pyrimidine-containing compound catabolism;   pyrimidine-containing compound degradation


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5-methylcytosine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TET1 tet methylcytosine dioxygenase 1 IEA InterPro GO_REF:0000002 NCBI chr10:68,560,337...68,700,794
Ensembl chr10:68,560,337...68,694,487
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 IDA
IEA
(PMID:24315485) UniProtKB
UniProt
PMID:24315485 GO_REF:0000104 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 IEA InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 2:73,982,036...74,135,394
Ensembl chr 2:73,986,404...74,108,176
JBrowse link
cytidine deamination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase IEA Ensembl GO_REF:0000107 NCBI chr12:8,602,170...8,612,970
Ensembl chr12:8,602,170...8,612,867
JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 IEA GOC GO_REF:0000108 NCBI chr12:7,649,400...7,670,599
Ensembl chr12:7,649,400...7,665,908
JBrowse link
G APOBEC2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 IEA GOC GO_REF:0000108 NCBI chr 6:41,053,202...41,064,891
Ensembl chr 6:41,053,304...41,064,511
JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A IEA GOC GO_REF:0000108 NCBI chr22:38,957,609...38,963,184
Ensembl chr22:38,952,741...38,992,778
JBrowse link
G APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid IEA GOC GO_REF:0000108 Ensembl chr22:38,952,741...38,992,778 JBrowse link
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B IEA GOC GO_REF:0000108 NCBI chr22:38,982,347...38,992,779
Ensembl chr22:38,982,347...38,992,804
JBrowse link
G APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C IDA (PMID:21632763) UniProtKB PMID:21632763 NCBI chr22:39,014,236...39,020,352
Ensembl chr22:39,014,257...39,020,352
JBrowse link
G APOBEC3D apolipoprotein B mRNA editing enzyme catalytic subunit 3D IEA GOC GO_REF:0000108 NCBI chr22:39,021,127...39,033,277
Ensembl chr22:39,021,113...39,033,277
JBrowse link
G APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F IEA GOC GO_REF:0000108 NCBI chr22:39,019,081...39,055,972
Ensembl chr22:39,040,604...39,055,972
JBrowse link
G APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G IDA (PMID:16378963) UniProtKB PMID:16378963 NCBI chr22:39,077,005...39,087,743
Ensembl chr22:39,077,067...39,087,743
JBrowse link
G APOBEC3H apolipoprotein B mRNA editing enzyme catalytic subunit 3H IEA GOC GO_REF:0000108 NCBI chr22:39,097,203...39,104,067
Ensembl chr22:39,097,224...39,104,067
JBrowse link
G CDA cytidine deaminase IDA
IBA
(PMID:9596658)
(PMID:21873635)
UniProtKB
GO_Central
PMID:9596658, PMID:21873635 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903
JBrowse link
G CDADC1 cytidine and dCMP deaminase domain containing 1 IDA (PMID:26945630) UniProtKB PMID:26945630 NCBI chr13:49,247,875...49,293,486
Ensembl chr13:49,247,925...49,293,485
JBrowse link
dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 IMP
IBA
(PMID:24467396)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
depyrimidination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBD4 methyl-CpG binding domain 4, DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:129,430,947...129,440,029
Ensembl chr 3:129,430,944...129,440,179
JBrowse link
G NEIL1 nei like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr15:75,346,638...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G NEIL2 nei like DNA glycosylase 2 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 8:11,769,710...11,787,345
Ensembl chr 8:11,769,639...11,787,345
JBrowse link
G NTHL1 nth like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr16:2,039,820...2,047,834
Ensembl chr16:2,039,815...2,047,866
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:54,121,274...54,188,985
Ensembl chr12:54,121,277...54,189,008
JBrowse link
G TDG thymine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:103,965,842...103,988,874
Ensembl chr12:103,965,822...103,988,874
JBrowse link
G UNG uracil DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,574...109,110,992
Ensembl chr12:109,097,574...109,110,992
JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 NOT IMP (PMID:24467396) UniProtKB PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5M 5',3'-nucleotidase, mitochondrial IEA Ensembl GO_REF:0000107 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL353753.1 putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:26,066,675...26,126,108
Ensembl chr 9:26,066,675...26,118,408
JBrowse link
G DUT deoxyuridine triphosphatase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr15:48,329,991...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic IDA
IBA
(PMID:10681516)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10681516, PMID:21873635 NCBI chr17:75,130,228...75,131,965
Ensembl chr17:75,130,225...75,131,757
JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
pyrimidine nucleobase catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRMP1 collapsin response mediator protein 1 NOT IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:5,820,764...5,893,086
Ensembl chr 4:5,748,084...5,893,086
JBrowse link
G DPYD dihydropyrimidine dehydrogenase IMP
ISS
(PMID:11988088) UniProtKB PMID:11988088 GO_REF:0000024 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DPYS dihydropyrimidinase IDA
IBA
(PMID:9718352)
(PMID:21873635)
UniProtKB
GO_Central
PMID:9718352, PMID:21873635 NCBI chr 8:104,379,429...104,467,074
Ensembl chr 8:104,330,324...104,467,055
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 NOT IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DPYSL3 dihydropyrimidinase like 3 NOT IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
JBrowse link
G DPYSL4 dihydropyrimidinase like 4 NOT IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:132,184,983...132,205,759
Ensembl chr10:132,186,948...132,205,759
JBrowse link
G DPYSL5 dihydropyrimidinase like 5 NOT IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351
JBrowse link
pyrimidine nucleoside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase TAS Reactome Reactome:R-HSA-73621 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DPYS dihydropyrimidinase TAS Reactome Reactome:R-HSA-73621 NCBI chr 8:104,379,429...104,467,074
Ensembl chr 8:104,330,324...104,467,055
JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic TAS Reactome Reactome:R-HSA-73621 NCBI chr17:75,130,228...75,131,965
Ensembl chr17:75,130,225...75,131,757
JBrowse link
G NT5C1A 5'-nucleotidase, cytosolic IA TAS Reactome Reactome:R-HSA-73621 NCBI chr 1:39,659,121...39,672,038
Ensembl chr 1:39,659,121...39,672,038
JBrowse link
G NT5C3A 5'-nucleotidase, cytosolic IIIA TAS Reactome Reactome:R-HSA-73621 NCBI chr 7:33,014,113...33,062,776
Ensembl chr 7:33,014,114...33,062,797
JBrowse link
G NT5E 5'-nucleotidase ecto TAS Reactome Reactome:R-HSA-73621 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791
JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial TAS Reactome Reactome:R-HSA-73621 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
G TYMP thymidine phosphorylase TAS Reactome Reactome:R-HSA-73621 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G UPB1 beta-ureidopropionase 1 TAS
IMP
(PMID:22525402) Reactome
UniProt
PMID:22525402 Reactome:R-HSA-73621 NCBI chr22:24,495,060...24,528,681
Ensembl chr22:24,494,107...24,528,390
JBrowse link
G UPP1 uridine phosphorylase 1 TAS Reactome Reactome:R-HSA-73621 NCBI chr 7:48,088,308...48,108,736
Ensembl chr 7:48,088,628...48,108,736
JBrowse link
G UPP2 uridine phosphorylase 2 TAS Reactome Reactome:R-HSA-73621 NCBI chr 2:157,995,179...158,136,154
Ensembl chr 2:157,876,702...158,136,154
JBrowse link
thymidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase IDA (PMID:1512248) UniProtKB PMID:1512248 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
thymine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 IMP
IBA
(PMID:23835272)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635, PMID:23835272 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
JBrowse link
G DPYD dihydropyrimidine dehydrogenase IDA
IBA
(PMID:10410956)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10410956, PMID:21873635 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DPYS dihydropyrimidinase ISS UniProtKB GO_REF:0000024 NCBI chr 8:104,379,429...104,467,074
Ensembl chr 8:104,330,324...104,467,055
JBrowse link
UDP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 IDA (PMID:9556635) UniProtKB PMID:9556635 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695
JBrowse link
uracil catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase IDA
IBA
(PMID:1512248), (PMID:18075467)
(PMID:21873635)
UniProtKB
GO_Central
PMID:1512248, PMID:18075467, PMID:21873635 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DPYS dihydropyrimidinase IMP
IDA
(PMID:18075467)
(PMID:10410956)
UniProtKB PMID:10410956, PMID:18075467 NCBI chr 8:104,379,429...104,467,074
Ensembl chr 8:104,330,324...104,467,055
JBrowse link
uridine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UPP1 uridine phosphorylase 1 IDA (PMID:7488099) UniProt PMID:7488099 NCBI chr 7:48,088,308...48,108,736
Ensembl chr 7:48,088,628...48,108,736
JBrowse link
G UPP2 uridine phosphorylase 2 IDA (PMID:12849978), (PMID:21855639) UniProt PMID:12849978, PMID:21855639 NCBI chr 2:157,995,179...158,136,154
Ensembl chr 2:157,876,702...158,136,154
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      nitrogen compound metabolic process 10481
        cellular nitrogen compound metabolic process 6772
          cellular nitrogen compound catabolic process 631
            pyrimidine-containing compound catabolic process 45
              5-methylcytosine catabolic process 3
              pyrimidine nucleobase catabolic process + 8
              pyrimidine nucleoside catabolic process + 24
              pyrimidine nucleotide catabolic process + 14
              thiamine diphosphate catabolic process 0
              thiamine-containing compound catabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.