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ONTOLOGY REPORT - ANNOTATIONS

Term:pyrimidine-containing compound biosynthetic process
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Accession:GO:0072528 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
Synonyms:exact_synonym: pyrimidine and derivative biosynthetic process;   pyrimidine-containing compound anabolism;   pyrimidine-containing compound biosynthesis;   pyrimidine-containing compound formation;   pyrimidine-containing compound synthesis


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'de novo' CTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctps1 CTP synthase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
'de novo' pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IDA
IBA
ISO		 PMID:21873635
(PMID:24332717)		 RGD PMID:24332717 PMID:1476792 PMID:21873635 RGD:5132591, RGD:13792537 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:1476792 PMID:21873635 RGD:5132591, RGD:13792537 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (MGI:5469988|PMID:23429704) RGD PMID:23429704 MGI:5469988 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
'de novo' UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IEA
ISO		 GO_REF:0000041
(PMID:25678555)
(MGI:6719158|PMID:33771897)		 UniProt
RGD		 PMID:25678555 PMID:33771897 GO_REF:0000041 MGI:6719158 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) involved_in IEA
ISO		 GO_REF:0000041
(MGI:6282496|PMID:30449682), (MGI:6720231|PMID:6249586)		 UniProt
RGD		 PMID:6249586 PMID:30449682 GO_REF:0000041 MGI:6282496 MGI:6720231 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IEA
ISO		 GO_REF:0000041
(MGI:1289111|PMID:2419341), (MGI:6720230|PMID:6154574)		 UniProt
RGD		 PMID:2419341 PMID:6154574 GO_REF:0000041 MGI:1289111 MGI:6720230 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
CDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:3010881 PMID:21873635 RGD:5133253, RGD:13792537 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
CTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctps1 CTP synthase 1 involved_in IBA
ISO		 PMID:21873635
(PMID:16179339), (PMID:24870241)		 RGD PMID:16179339 PMID:24870241 PMID:21873635 RGD:13792537 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:15,104,907...15,113,281 JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IDA RGD PMID:1316151 RGD:729254 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:15,114,624...15,118,479 JBrowse link
G Nme5 NME/NM23 family member 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301 		JBrowse link
G Nme7 NME/NM23 family member 7 involved_in IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr13:76,657,303...76,786,768
Ensembl chr13:76,657,367...76,786,765 		JBrowse link
CTP salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uck1 uridine-cytidine kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:15,538,580...15,544,465
Ensembl chr 3:15,538,591...15,544,465 		JBrowse link
G Uck2 uridine-cytidine kinase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:168,674,849...168,687,513
Ensembl chr 3:168,674,849...168,698,091 		JBrowse link
dCDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IDA RGD PMID:192455 RGD:5133256 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
dTDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk2 cytidine/uridine monophosphate kinase 2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:192455 PMID:21873635 RGD:5133256, RGD:13792537 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Dtymk deoxythymidylate kinase acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 (MGI:77260|PMID:8845311)
PMID:21873635		 RGD PMID:8845311 PMID:220041 PMID:21873635 MGI:77260, RGD:5133687, RGD:13792537 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
dTMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dctd dCMP deaminase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446 		JBrowse link
G Dut deoxyuridine triphosphatase involved_in ISO (PMID:10952785), (PMID:15322254) RGD PMID:10952785 PMID:15322254 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (MGI:3849912|PMID:19513116) RGD PMID:19513116 MGI:3849912 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Tyms thymidylate synthetase involved_in IDA
ISO
IBA		 (MGI:5300404|PMID:22057276)
PMID:21873635
(PMID:11278511), (PMID:15093541), (PMID:8845352)		 RGD PMID:8845352 PMID:11278511 PMID:15093541 PMID:22057276 PMID:9894005 More... MGI:5300404, RGD:1545055, RGD:13792537 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
dTTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk2 cytidine/uridine monophosphate kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Dtymk deoxythymidylate kinase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:220041 PMID:21873635 RGD:5133687, RGD:13792537 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
G Tbpl1 TATA-box binding protein like 1 acts_upstream_of_or_within ISO MGI:2182539 (MGI:2159505|PMID:11861477) RGD PMID:11861477 MGI:2159505 NCBI chr 1:22,777,892...22,803,305
Ensembl chr 1:22,778,459...22,803,122
Ensembl chr 1:22,778,459...22,803,122 		JBrowse link
G Tyms thymidylate synthetase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
dUDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IDA RGD PMID:3010881 RGD:5133253 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:192455 PMID:21873635 RGD:5133256, RGD:13792537 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Dtymk deoxythymidylate kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
dUMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001512.1 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 Ensembl chr 1:48,369,044...48,369,595 JBrowse link
G Dctd dCMP deaminase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446 		JBrowse link
G Dut deoxyuridine triphosphatase involved_in IDA
IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt
RGD		 PMID:3032103 PMID:21873635 PMID:1315924 GO_REF:0000041, RGD:2300191, RGD:13792537, RGD:2301218 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctps1 CTP synthase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
pyrimidine nucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
pyrimidine ribonucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhodh dihydroorotate dehydrogenase (quinone) involved_in IBA PMID:21873635 GO_Central PMID:21873635 PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
thiamine diphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpk1 thiamin pyrophosphokinase 1 involved_in IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 4:72,170,134...72,557,707
Ensembl chr 4:72,170,134...72,557,694 		JBrowse link
UDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in ISO (PMID:25678555) RGD PMID:25678555 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 involved_in IDA
IEA
ISO
IBA		 GO_REF:0000107
(PMID:11912132)
PMID:21873635		 Ensembl
RGD		 PMID:11912132 PMID:3010881 PMID:21873635 GO_REF:0000107, RGD:5133253, RGD:13792537 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) involved_in ISO (MGI:6282496|PMID:30449682), (MGI:6720231|PMID:6249586) RGD PMID:6249586 PMID:30449682 MGI:6282496 MGI:6720231 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Umps uridine monophosphate synthetase involved_in ISO (MGI:1289111|PMID:2419341), (MGI:6720230|PMID:6154574) RGD PMID:2419341 PMID:6154574 MGI:1289111 MGI:6720230 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umps uridine monophosphate synthetase involved_in IDA
ISO
IBA		 (PMID:11730338), (PMID:6893554)
PMID:21873635		 RGD PMID:6893554 PMID:11730338 PMID:6134725 PMID:21873635 RGD:5132277, RGD:13792537 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
G Uprt uracil phosphoribosyltransferase homolog IDA RGD PMID:1476792 RGD:5132591 NCBI chr  X:69,516,573...69,546,811
Ensembl chr  X:69,516,738...69,546,797 		JBrowse link
UMP salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase involved_in ISO (MGI:6720232|PMID:6498945) RGD PMID:6498945 MGI:6720232 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Uck1 uridine-cytidine kinase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:84399|PMID:8951040)		 UniProt
RGD		 PMID:8951040 GO_REF:0000041 MGI:84399 NCBI chr 3:15,538,580...15,544,465
Ensembl chr 3:15,538,591...15,544,465 		JBrowse link
G Uck2 uridine-cytidine kinase 2 involved_in IEA
ISO		 GO_REF:0000041
(PMID:27239701)		 UniProt
RGD		 PMID:27239701 GO_REF:0000041 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:168,674,849...168,687,513
Ensembl chr 3:168,674,849...168,698,091 		JBrowse link
G Upp1 uridine phosphorylase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:3586453|PMID:11956089)		 UniProt
RGD		 PMID:11956089 GO_REF:0000041 MGI:3586453 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462 		JBrowse link
G Upp2 uridine phosphorylase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417 		JBrowse link
UTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:10659854 PMID:21873635 RGD:2303528, RGD:13792537 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:15,104,907...15,113,281 JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IDA RGD PMID:1316151 RGD:729254 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:15,114,624...15,118,479 JBrowse link
G Nme5 NME/NM23 family member 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301 		JBrowse link
G Nme7 NME/NM23 family member 7 involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr13:76,657,303...76,786,768
Ensembl chr13:76,657,367...76,786,765 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      biosynthetic process 6089
        cellular biosynthetic process 5932
          heterocycle biosynthetic process 3844
            pyrimidine-containing compound biosynthetic process 32
              5-methylcytosine biosynthetic process 0
              pyrimidine nucleobase biosynthetic process + 8
              pyrimidine nucleoside biosynthetic process + 0
              pyrimidine nucleotide biosynthetic process + 29
              thiamine-containing compound biosynthetic process + 1
paths to the root