Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:pyrimidine-containing compound metabolic process
go back to main search page
Accession:GO:0072527 term browser browse the term
Definition:The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
Synonyms:exact_synonym: pyrimidine and derivative metabolic process;   pyrimidine-containing compound metabolism


show annotations for term's descendants           Sort by:
 
'de novo' pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO (PMID:24332717) UniProtKB
RGD
PMID:1476792, PMID:24332717 RGD:5132591 NCBI chrNW_004936493:5,308,268...5,332,934 JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) ISO RGD PMID:1476792 RGD:5132591 NCBI chrNW_004936475:21,863,627...21,877,660 JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO (MGI:5469988|PMID:23429704) CACAO PMID:23429704 MGI:5469988 NCBI chrNW_004936474:158,376...282,310 JBrowse link
5-methylcytosine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tet2 tet methylcytosine dioxygenase 2 ISO (PMID:24315485) UniProtKB PMID:24315485 NCBI chrNW_004936752:440,137...577,339 JBrowse link
5-methylcytosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tet2 tet methylcytosine dioxygenase 2 ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chrNW_004936752:440,137...577,339 JBrowse link
CDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:3010881 RGD:5133253 NCBI chrNW_004936474:28,147,459...28,180,779 JBrowse link
CTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctps1 CTP synthase 1 ISO (PMID:16179339)
(PMID:24870241)
UniProtKB PMID:16179339, PMID:24870241 NCBI chrNW_004936474:22,611,037...22,633,208 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO RGD PMID:1316151 RGD:729254 NCBI chrNW_004936490:10,634,788...10,640,182 JBrowse link
cytidine deamination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase ISO (MGI:2656023|PMID:12692563) UniProt PMID:12692563 MGI:2656023 NCBI chrNW_004936870:25,039...34,601 JBrowse link
G Cda cytidine deaminase ISO (PMID:9596658) RGD
UniProtKB
PMID:675715, PMID:9596658 RGD:2316616 NCBI chrNW_004936474:6,543,295...6,564,575 JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 ISO (PMID:26945630) UniProtKB PMID:26945630 NCBI chrNW_004936565:2,336,613...2,395,816 JBrowse link
cytosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen-activated protein kinase 1 ISO (MGI:3510481|PMID:15284227) MGI PMID:15284227 MGI:3510481 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chrNW_004936752:440,137...577,339 JBrowse link
dCDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:192455 RGD:5133256 NCBI chrNW_004936474:28,147,459...28,180,779 JBrowse link
dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dctpp1 dCTP pyrophosphatase 1 ISO (PMID:24467396) UniProtKB PMID:24467396 NCBI chrNW_004936501:12,880,745...12,884,240 JBrowse link
deoxycytidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase ISO RGD PMID:7686601, PMID:8305745 RGD:2300395, RGD:2300398 NCBI chrNW_004936598:3,819,239...3,846,692 JBrowse link
G Tk2 thymidine kinase 2 ISO RGD PMID:21444706 RGD:5134349 NCBI chrNW_004936475:16,851,380...16,875,195 JBrowse link
dTDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk2 cytidine/uridine monophosphate kinase 2 ISO RGD PMID:192455 RGD:5133256 NCBI chrNW_004936532:3,896,654...3,908,184 JBrowse link
G Dtymk deoxythymidylate kinase ISO (MGI:77260|PMID:8845311) RGD
MGI
PMID:220041, PMID:8845311 MGI:77260, RGD:5133687 NCBI chrNW_004936745:282,199...289,273 JBrowse link
dTMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 ISO (MGI:3849912|PMID:19513116) BHF-UCL PMID:19513116 MGI:3849912 NCBI chrNW_004936741:1,849,239...1,877,724 JBrowse link
G Tyms thymidylate synthetase ISO (PMID:11278511), (PMID:15093541), (PMID:8845352) CAFA
RGD
PMID:8845352, PMID:9894005, PMID:11278511, PMID:15093541 RGD:1545055 NCBI chrNW_004936550:33,797...42,233 JBrowse link
dTTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtymk deoxythymidylate kinase ISO RGD PMID:220041 RGD:5133687 NCBI chrNW_004936745:282,199...289,273 JBrowse link
G Tbpl1 TATA-box binding protein like 1 ISO (MGI:2159505|PMID:11861477) MGI PMID:11861477 MGI:2159505 NCBI chrNW_004936560:1,797,791...1,830,199 JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dctpp1 dCTP pyrophosphatase 1 NOT ISO (PMID:24467396) UniProtKB PMID:24467396 NCBI chrNW_004936501:12,880,745...12,884,240 JBrowse link
dUDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:3010881 RGD:5133253 NCBI chrNW_004936474:28,147,459...28,180,779 JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 ISO RGD PMID:192455 RGD:5133256 NCBI chrNW_004936532:3,896,654...3,908,184 JBrowse link
dUMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dut deoxyuridine triphosphatase ISO RGD PMID:1315924, PMID:3032103 RGD:2300191, RGD:2301218 NCBI chrNW_004936471:10,670,604...10,681,356 JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5m 5',3'-nucleotidase, mitochondrial ISO (MGI:2388903|PMID:12234672) MGI PMID:12234672 MGI:2388903 NCBI chrNW_004936741:950,681...999,290 JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dut deoxyuridine triphosphatase ISO RGD PMID:1315924, PMID:3032103 RGD:2300191, RGD:2301218 NCBI chrNW_004936471:10,670,604...10,681,356 JBrowse link
pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5c 5', 3'-nucleotidase, cytosolic ISO (PMID:10681516) UniProtKB PMID:10681516 NCBI chrNW_004936594:430,274...432,027 JBrowse link
pyrimidine nucleobase catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase ISO (PMID:11988088)
(MGI:2657070|PMID:12651209)
UniProtKB
MGI
RGD
PMID:1629785, PMID:11988088, PMID:12651209 MGI:2657070, RGD:1599794 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
G Dpys dihydropyrimidinase ISO (PMID:9718352) UniProtKB PMID:9718352 NCBI chrNW_004936470:39,564,431...39,637,394 JBrowse link
pyrimidine nucleobase metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO orotic acid RGD PMID:10204803 RGD:5133695 NCBI chrNW_004936498:815,401...848,749 JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO orotic acid RGD PMID:10204803 RGD:5133695 NCBI chrNW_004936532:6,348,041...6,390,144 JBrowse link
G Tyms thymidylate synthetase ISO 5-fluorocytosine RGD PMID:9524100 RGD:5133447 NCBI chrNW_004936550:33,797...42,233 JBrowse link
pyrimidine nucleoside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upb1 beta-ureidopropionase 1 ISO (PMID:22525402) UniProt PMID:22525402 NCBI chrNW_004936619:668,380...713,720 JBrowse link
pyrimidine nucleoside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase ISO (PMID:1590793)
(PMID:9924029)
CAFA PMID:1590793, PMID:9924029 NCBI chrNW_004936629:315,609...320,356 JBrowse link
pyrimidine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase ISO (PMID:12808445) UniProtKB PMID:12808445 NCBI chrNW_004936598:3,819,239...3,846,692 JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 ISO (PMID:11342463) UniProtKB PMID:11342463 NCBI chrNW_004937067:41,573...129,386 JBrowse link
G Upp1 uridine phosphorylase 1 ISO (MGI:3584214|PMID:15772079) MGI PMID:15772079 MGI:3584214 NCBI chrNW_004936478:22,508,602...22,531,604 JBrowse link
thiamine diphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thtpa thiamine triphosphatase ISO (MGI:3796446|PMID:18276586) UniProt PMID:18276586 MGI:3796446 NCBI chrNW_004936722:858,119...904,630 JBrowse link
thiamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 ISO (MGI:3849266|PMID:18940592) UniProt PMID:18940592 MGI:3849266 NCBI chrNW_004936529:5,661,772...5,723,108 JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 ISO (MGI:1350425|PMID:10567383) MGI PMID:10567383 MGI:1350425 NCBI chrNW_004936527:1,450,918...1,786,431 JBrowse link
thymidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase ISO (PMID:1512248) UniProtKB PMID:1512248 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
thymidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tk1 thymidine kinase 1 ISO phosphorylation RGD PMID:6642140 RGD:2317232 NCBI chrNW_004936594:2,784,891...2,794,693 JBrowse link
G Tk2 thymidine kinase 2 ISO RGD PMID:21444706 RGD:5134349 NCBI chrNW_004936475:16,851,380...16,875,195 JBrowse link
thymine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh6a1 aldehyde dehydrogenase 6 family member A1 ISO (PMID:23835272) BHF-UCL
RGD
PMID:2768248, PMID:23835272 RGD:1599052 NCBI chrNW_004936488:3,320,357...3,340,463 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO (PMID:10410956) UniProtKB PMID:10410956 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
G Dpys dihydropyrimidinase ISO PMID:8307005 UniProt PMID:8307005 RGD:1624990 NCBI chrNW_004936470:39,564,431...39,637,394 JBrowse link
thymine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh6a1 aldehyde dehydrogenase 6 family member A1 ISO PMID:2768248 UniProt PMID:2768248 RGD:1599052 NCBI chrNW_004936488:3,320,357...3,340,463 JBrowse link
UDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:3010881 RGD:5133253 NCBI chrNW_004936474:28,147,459...28,180,779 JBrowse link
UDP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 ISO (PMID:9556635) UniProtKB PMID:9556635 NCBI chrNW_004936555:6,896,661...6,920,333 JBrowse link
UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umps uridine monophosphate synthetase ISO (PMID:11730338), (PMID:6893554) UniProtKB
RGD
PMID:6134725, PMID:6893554, PMID:11730338 RGD:5132277 NCBI chrNW_004936725:553,278...564,846 JBrowse link
G Uprt uracil phosphoribosyltransferase homolog ISO RGD PMID:1476792 RGD:5132591 NCBI chrNW_004936683:1,432,004...1,454,004 JBrowse link
uracil catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase ISO (PMID:1512248), (PMID:18075467) UniProtKB PMID:1512248, PMID:18075467 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
G Dpys dihydropyrimidinase ISO (PMID:18075467)
PMID:8307005
(PMID:10410956)
UniProtKB
UniProt
PMID:8307005, PMID:10410956, PMID:18075467 RGD:1624990 NCBI chrNW_004936470:39,564,431...39,637,394 JBrowse link
uracil metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase ISO RGD PMID:7626590 RGD:1624989 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
G Dpys dihydropyrimidinase ISO RGD PMID:7626590, PMID:8307005 RGD:1624989, RGD:1624990 NCBI chrNW_004936470:39,564,431...39,637,394 JBrowse link
G Tyms thymidylate synthetase ISO RGD PMID:2043679 RGD:5133426 NCBI chrNW_004936550:33,797...42,233 JBrowse link
uridine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upp1 uridine phosphorylase 1 ISO (PMID:7488099)
(MGI:5476603|PMID:23355744), (MGI:73237|PMID:7744869)
UniProt
CACAO
PMID:7488099, PMID:7744869, PMID:23355744 MGI:5476603, MGI:73237 NCBI chrNW_004936478:22,508,602...22,531,604 JBrowse link
G Upp2 uridine phosphorylase 2 ISO (PMID:12849978), (PMID:21855639)
(MGI:2683856|PMID:14715930)
UniProt PMID:12849978, PMID:14715930, PMID:21855639 MGI:2683856 NCBI chrNW_004936469:20,465,767...20,513,084 JBrowse link
uridine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upp1 uridine phosphorylase 1 ISO (MGI:3584214|PMID:15772079) MGI PMID:15772079 MGI:3584214 NCBI chrNW_004936478:22,508,602...22,531,604 JBrowse link
UTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chrNW_004936493:5,308,268...5,332,934 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO RGD PMID:1316151 RGD:729254 NCBI chrNW_004936490:10,634,788...10,640,182 JBrowse link
UTP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak3 adenylate kinase 3 ISO (PMID:11485571) BHF-UCL PMID:11485571 NCBI chrNW_004936503:497,391...517,011 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      nitrogen compound metabolic process 6467
        cellular nitrogen compound metabolic process 4089
          pyrimidine-containing compound metabolic process 40
            5-methylcytosine metabolic process + 1
            orotic acid metabolic process 0
            pyrimidine nucleobase metabolic process + 11
            pyrimidine nucleoside metabolic process + 11
            pyrimidine nucleotide metabolic process + 20
            pyrimidine-containing compound biosynthetic process + 14
            pyrimidine-containing compound catabolic process + 15
            thiamine diphosphate metabolic process + 1
            thiamine-containing compound metabolic process + 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.