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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine-containing compound biosynthetic process
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Accession:GO:0072525 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
Synonyms:exact_synonym: pyridine and derivative biosynthetic process;   pyridine-containing compound anabolism;   pyridine-containing compound biosynthesis;   pyridine-containing compound formation;   pyridine-containing compound synthesis


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Aspdh aspartate dehydrogenase domain containing IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:100,471,066...100,473,327
Ensembl chr 1:100,470,722...100,473,459
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kynu kynureninase ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Nadsyn1 NAD synthetase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO
IEA
(MGI:MGI:3522067|PMID:15381699)
GO_REF:0000041
RGD
UniProt
PMID:15381699 GO_REF:0000041, MGI:MGI:3522067 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Naprt nicotinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IEA
ISO
IBA
GO_REF:0000041
(MGI:MGI:3522067|PMID:15381699), (MGI:MGI:3654729|PMID:16914673), (MGI:MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699, PMID:16914673, PMID:27735788, PMID:21873635 GO_REF:0000041, MGI:MGI:3522067, MGI:MGI:3654729, MGI:MGI:6206974, RGD:13792537 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 IMP
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:22449973, PMID:21873635 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:70,379,346...70,559,311
Ensembl chr13:70,379,346...70,559,458
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 ISO
IBA
IEA
(MGI:MGI:3654729|PMID:16914673)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:16914673, PMID:21873635 GO_REF:0000041, MGI:MGI:3654729, RGD:13792537 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
NAD salvage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:MGI:2182739 (MGI:MGI:1097071|PMID:9330624), (MGI:MGI:1202104|PMID:9539108), (MGI:MGI:1261671|PMID:9627357), (MGI:MGI:1349468|PMID:3377761), (MGI:MGI:2387959|PMID:10627286), (MGI:MGI:3522057|PMID:15271799), (MGI:MGI:3607389|PMID:14757696), (MGI:MGI:3694178|PMID:15998684), (MGI:MGI:49164|PMID:1953691), (MGI:MGI:54902|PMID:7439685), (MGI:MGI:85983|PMID:9067418), (MGI:MGI:87492|PMID:9169132) RGD PMID:1953691, PMID:3377761, PMID:7439685, PMID:9067418, PMID:9169132, PMID:9330624, PMID:9539108, PMID:9627357, PMID:10627286, PMID:14757696, PMID:15271799, PMID:15998684 MGI:MGI:1097071, MGI:MGI:1202104, MGI:MGI:1261671, MGI:MGI:1349468, MGI:MGI:2387959, MGI:MGI:3522057, MGI:MGI:3607389, MGI:MGI:3694178, MGI:MGI:49164, MGI:MGI:54902, MGI:MGI:85983, MGI:MGI:87492 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Nadk NAD kinase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069, PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 2:58,462,588...58,504,735
Ensembl chr 2:58,462,588...58,504,728
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO
ISS
IEA
(PMID:12140278)
GO_REF:0000024
GO_REF:0000104
RGD
UniProt
PMID:12140278 GO_REF:0000024, GO_REF:0000104 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:10,883,952...10,912,870
Ensembl chr20:10,889,573...10,912,769
JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IDA RGD PMID:2988502 RGD:2303018 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase ISO
IBA
(PMID:12824491)
PMID:21873635
RGD PMID:12824491, PMID:21873635 RGD:13792537 NCBI chr10:84,874,926...84,881,190
Ensembl chr10:84,874,927...84,881,190
JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:84,874,926...84,881,190
Ensembl chr10:84,874,927...84,881,190
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA
ISO
GO_REF:0000104
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Htt huntingtin ISO MGI:MGI:1861934|MGI:MGI:1861935 (MGI:MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:MGI:3653320 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      biosynthetic process 6225
        cellular biosynthetic process 6060
          heterocycle biosynthetic process 3959
            pyridine-containing compound biosynthetic process 24
              aspyridone A biosynthetic process 0
              aspyridone B biosynthetic process 0
              nicotinate biosynthetic process 0
              picolinic acid biosynthetic process 0
              pyridine biosynthetic process 0
              pyridine nucleoside biosynthetic process + 0
              pyridine nucleotide biosynthetic process + 19
              quinolinate biosynthetic process + 5
              vitamin B6 biosynthetic process + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.