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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine-containing compound biosynthetic process
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Accession:GO:0072525 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
Synonyms:exact_synonym: pyridine and derivative biosynthetic process;   pyridine-containing compound anabolism;   pyridine-containing compound biosynthesis;   pyridine-containing compound formation;   pyridine-containing compound synthesis



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'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
IEA
ISS
(PMID:31883644)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,981,559...199,009,853 JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718 JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr 6:16,598,325...16,617,590 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:74,133,259...74,145,328 JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:67,459,158...67,498,052 JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:90,089,340...90,121,108 JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:48,188,286...48,338,996 JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:94,956,327...94,960,722 JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:16,598,325...16,617,590 JBrowse link
G Kynu kynureninase involved_in ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:48,188,286...48,338,996 JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr 1:198,981,559...199,009,853 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000041
(PMID:15381699)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:15381699 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:55,152,756...55,189,547 JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:107,576,645...107,580,102 JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000041
GO_REF:0000033
(PMID:27735788)
(PMID:15381699), (PMID:16914673)
UniProt
GO_Central
RGD
PMID:15381699 PMID:16914673 PMID:27735788 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:159,910,242...159,928,201 JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IBA
IEA
GO_REF:0000033
GO_REF:0000041
GO_Central
UniProt
RGD
PMID:22449973 GO_REF:0000033 GO_REF:0000041, RGD:13782043 NCBI chr13:65,105,950...65,277,350 JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000041
GO_REF:0000033
(PMID:16914673)
UniProt
GO_Central
RGD
PMID:16914673 GO_REF:0000033 GO_REF:0000041 NCBI chr 8:107,771,124...107,888,528 JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:225,475,975...225,503,414 JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA
GO_REF:0000033
GO_REF:0000041
GO_Central
UniProt
RGD
PMID:8694849 GO_REF:0000033 GO_REF:0000041, RGD:2289495 NCBI chr 1:181,718,189...181,733,486 JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA
ISO
GO_REF:0000033
(PMID:17604275)
GO_Central
RGD
PMID:17604275 GO_REF:0000033 NCBI chr 7:107,576,645...107,580,102 JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (PMID:10627286), (PMID:14757696), (PMID:15271799), (PMID:15998684), (PMID:1953691), (PMID:3377761), (PMID:7439685), (PMID:9067418), (PMID:9169132), (PMID:9330624), (PMID:9539108), (PMID:9627357) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... NCBI chr  X:157,352,364...157,372,144 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:143,447,925...143,467,248 JBrowse link
G Nadk NAD kinase involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:22550069 GO_REF:0000033, RGD:13703105 NCBI chr 5:171,427,973...171,458,586 JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:59,844,854...59,886,989 JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12140278)
GO_REF:0000104
UniProt
RGD
PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:39,200,412...39,245,954 JBrowse link
pyridine nucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:16,598,325...16,617,590 JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase involved_in IEA
IBA
GO_REF:0000002
GO_REF:0000033
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr20:10,209,975...10,232,012 JBrowse link
G Pdxkl1 pyridoxal kinase like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,162,634...10,192,271 JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IDA RGD PMID:2988502 RGD:2303018 NCBI chr20:10,209,975...10,232,012 JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in ISO
IBA
(PMID:12824491)
GO_REF:0000033
RGD
GO_Central
PMID:12824491 GO_REF:0000033 NCBI chr10:81,924,584...81,930,844 JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:81,924,584...81,930,844 JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IEA
(PMID:28792876)
GO_REF:0000104
RGD
UniProt
PMID:28792876 GO_REF:0000104 NCBI chr 6:16,598,325...16,617,590 JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1861934|MGI:1861935 (PMID:16697652) RGD PMID:16697652 NCBI chr14:75,845,836...75,996,094 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in ISO
IEA
(PMID:2419335)
GO_REF:0000107
RGD
Ensembl
PMID:2419335 GO_REF:0000107 NCBI chr16:74,133,259...74,145,328 JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:90,089,340...90,121,108 JBrowse link
G Kynu kynureninase involved_in ISO
IEA
(PMID:9291104)
GO_REF:0000104
RGD
UniProt
PMID:9291104 GO_REF:0000104 NCBI chr 3:48,188,286...48,338,996 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      metabolic process 12157
        pyridine-containing compound metabolic process 248
          pyridine-containing compound biosynthetic process 24
            aspyridone A biosynthetic process 0
            aspyridone B biosynthetic process 0
            ilicicolin H biosynthetic process 0
            nicotinate biosynthetic process 0
            picolinic acid biosynthetic process 0
            pyridine biosynthetic process 0
            pyridine nucleoside biosynthetic process + 0
            pyridine nucleotide biosynthetic process + 19
            quinolinate biosynthetic process + 6
            vitamin B6 biosynthetic process + 3
paths to the root