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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine-containing compound biosynthetic process
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Accession:GO:0072525 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
Synonyms:exact_synonym: pyridine and derivative biosynthetic process;   pyridine-containing compound anabolism;   pyridine-containing compound biosynthesis;   pyridine-containing compound formation;   pyridine-containing compound synthesis



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'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
IEA
ISS
(PMID:31883644)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Kynu kynureninase involved_in ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000041
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 GO_REF:0000041 MGI:3522067 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000041
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)
(MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699 PMID:16914673 PMID:27735788 PMID:21873635 GO_REF:0000041 MGI:3522067 MGI:3654729 MGI:6206974, RGD:13792537 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IEA
IBA
GO_REF:0000002
GO_REF:0000041
PMID:21873635
InterPro
UniProt
RGD
PMID:22449973 PMID:21873635 GO_REF:0000002 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3654729|PMID:16914673)
GO_REF:0000041
RGD
UniProt
PMID:16914673 PMID:21873635 GO_REF:0000041 MGI:3654729, RGD:13792537 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:8694849 PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3522057|PMID:15271799), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:54902|PMID:7439685), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Nadk NAD kinase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069 PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:58,117,674...58,159,815
Ensembl chr 2:58,117,674...58,159,808
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12140278)
GO_REF:0000104
UniProt
RGD
PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase involved_in IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr20:10,210,393...10,231,937
Ensembl chr20:10,210,289...10,232,110
JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:10,162,934...10,192,610 JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IDA RGD PMID:2988502 RGD:2303018 NCBI chr20:10,210,393...10,231,937
Ensembl chr20:10,210,289...10,232,110
JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in IBA
ISO
PMID:21873635
(PMID:12824491)
RGD PMID:12824491 PMID:21873635 RGD:13792537 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871
JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IEA
(PMID:28792876)
GO_REF:0000104
RGD
UniProt
PMID:28792876 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1861934|MGI:1861935 (MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:3653320 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    metabolic process 11735
      biosynthetic process 6020
        cellular biosynthetic process 5862
          heterocycle biosynthetic process 3792
            pyridine-containing compound biosynthetic process 24
              aspyridone A biosynthetic process 0
              aspyridone B biosynthetic process 0
              nicotinate biosynthetic process 0
              picolinic acid biosynthetic process 0
              pyridine biosynthetic process 0
              pyridine nucleoside biosynthetic process + 0
              pyridine nucleotide biosynthetic process + 19
              quinolinate biosynthetic process + 5
              vitamin B6 biosynthetic process + 3
paths to the root