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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal stem cell differentiation
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Accession:GO:0072497 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.



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mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO (PMID:24023731)
MGI:2148567|MGI:3841145 (PMID:30478225)
RGD PMID:24023731 PMID:30478225 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Krt18 keratin 18 IEP RGD PMID:18484094 RGD:27226811 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Mir346 microRNA 346 involved_in ISO (PMID:24023731) RGD PMID:24023731 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 acts_upstream_of_or_within ISO (PMID:33323934) RGD PMID:33323934 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467
JBrowse link
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
MGI:2148567|MGI:3841145 (PMID:30478225)
Ensembl
RGD
PMID:30478225 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rest RE1-silencing transcription factor involved_in ISO
ISS
IEA
(PMID:20942606)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20942606 GO_REF:0000024 GO_REF:0000107 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO
IEA
(PMID:24023731)
GO_REF:0000107
RGD
Ensembl
PMID:24023731 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Mir154 microRNA 154 acts_upstream_of_or_within ISO (PMID:25959411) RGD PMID:25959411 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO (PMID:18570921) RGD PMID:18570921 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
positive regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ltbp3 latent transforming growth factor beta binding protein 3 involved_in ISO (PMID:18672106) RGD PMID:18672106 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852
JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IEA
(PMID:21401405)
GO_REF:0000107
RGD
Ensembl
PMID:21401405 GO_REF:0000107 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
ISS
(PMID:21401405)
GO_REF:0000024
RGD
UniProt
PMID:21401405 GO_REF:0000024 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd1 frizzled class receptor 1 involved_in ISO (PMID:20039315) RGD PMID:20039315 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:27798620 RGD:41404703 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21596750)
Ensembl
UniProt
RGD
PMID:21596750 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Slc4a11 solute carrier family 4 member 11 involved_in ISO (PMID:33247189) RGD PMID:33247189 NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674
JBrowse link
G Wnt3 Wnt family member 3 involved_in ISO (PMID:20039315) RGD PMID:20039315 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    developmental process 7036
      cellular developmental process 4763
        cell differentiation 4762
          stem cell differentiation 280
            mesenchymal stem cell differentiation 16
              amniotic stem cell differentiation + 1
              canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation 1
              mesenchymal stem cell differentiation involved in nephron morphogenesis + 0
              negative regulation of mesenchymal stem cell differentiation + 3
              positive regulation of mesenchymal stem cell differentiation + 4
              regulation of mesenchymal stem cell differentiation + 12
paths to the root