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ONTOLOGY REPORT - ANNOTATIONS


Term:blood coagulation, fibrin clot formation
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Accession:GO:0072378 term browser browse the term
Definition:A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
Comment:See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.



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blood coagulation, fibrin clot formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F13a1 coagulation factor XIII A1 chain involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
MGI:5645817 (MGI:5645809|PMID:18224415)
GO_REF:0000107
(PMID:27363989)
PMID:21873635
UniProt
RGD
Ensembl
PMID:18224415 PMID:27363989 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5645809, RGD:13792537 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G F13b coagulation factor XIII B chain involved_in ISO
IEA
(PMID:27363989)
GO_REF:0000107
RGD
Ensembl
PMID:27363989 GO_REF:0000107 NCBI chr13:51,130,851...51,156,383
Ensembl chr13:51,130,920...51,156,381
JBrowse link
G Fbln1 fibulin 1 involved_in ISO (PMID:7642629) RGD PMID:7642629 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IBA
(PMID:16846481)
PMID:21873635
RGD PMID:16846481 PMID:21873635 RGD:13792537 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in IBA
ISO
PMID:21873635
(PMID:16846481)
(PMID:11001902)
(PMID:11001902), (PMID:16846481)
RGD PMID:11001902 PMID:16846481 PMID:21873635 RGD:13792537 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fn1 fibronectin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
blood coagulation, common pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II involved_in ISO (PMID:22457833) RGD PMID:22457833 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
(PMID:12706644)
PMID:21873635
(PMID:10891444)
RGD PMID:10891444 PMID:12706644 PMID:21873635 RGD:13792537 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
blood coagulation, extrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F5 coagulation factor V TAS RGD PMID:15172885 RGD:1601118 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
blood coagulation, intrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:4052628)
GO_REF:0000107
RGD
Ensembl
PMID:4052628 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G F11 coagulation factor XI involved_in ISO (PMID:10823824) RGD PMID:10823824 NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F8 coagulation factor VIII involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:2513867 PMID:21873635 RGD:1582368, RGD:13792537 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
JBrowse link
G F9 coagulation factor IX involved_in ISO (PMID:8632006) RGD PMID:8632006 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO
IEA
(PMID:10501658)
GO_REF:0000107
RGD
Ensembl
PMID:10501658 GO_REF:0000107 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO
IEA
(PMID:10501658)
GO_REF:0000107
RGD
Ensembl
PMID:10501658 GO_REF:0000107 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO
IEA
(PMID:10501658)
GO_REF:0000107
RGD
Ensembl
PMID:10501658 GO_REF:0000107 NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110
JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:874082) RGD PMID:874082 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
JBrowse link
regulation of blood coagulation, intrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinc1 serpin family C member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    response to stimulus 10556
      protein activation cascade 25
        blood coagulation, fibrin clot formation 19
          blood coagulation, common pathway + 2
          blood coagulation, extrinsic pathway + 1
          blood coagulation, intrinsic pathway + 10
Path 2
Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological quality 4234
        regulation of body fluid levels 430
          hemostasis 197
            blood coagulation 194
              blood coagulation, fibrin clot formation 19
                blood coagulation, common pathway + 2
                blood coagulation, extrinsic pathway + 1
                blood coagulation, intrinsic pathway + 10
paths to the root