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ONTOLOGY REPORT - ANNOTATIONS

Term:intrinsic apoptotic signaling pathway by p53 class mediator
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Accession:GO:0072332 term browser browse the term
Definition:The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
Synonyms:exact_synonym: intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
 related_synonym: signal transduction by p53 class mediator resulting in induction of apoptosis


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intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10479688) Ensembl
MGI		 PMID:10479688 GO_REF:0000107 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238 		JBrowse link
G CASP6 caspase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836 		JBrowse link
G CEP63 centrosomal protein 63 acts_upstream_of ISO (PMID:26158450) MGI PMID:26158450 NCBI chr 3:131,532,450...131,609,240
Ensembl chr 3:139,003,898...139,092,680 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142 		JBrowse link
G E2F1 E2F transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11095619) Ensembl
MGI		 PMID:11095619 GO_REF:0000107 NCBI chr20:29,963,083...29,973,860
Ensembl chr20:31,103,764...31,110,604 		JBrowse link
G E2F2 E2F transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11095619) Ensembl
MGI		 PMID:11095619 GO_REF:0000107 NCBI chr 1:22,696,695...22,722,840
Ensembl chr 1:23,683,293...23,707,951 		JBrowse link
G EDA2R ectodysplasin A2 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20434500) Ensembl
MGI		 PMID:20434500 GO_REF:0000107 NCBI chr  X:55,786,361...55,830,798
Ensembl chr  X:65,850,306...65,894,975 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18545656) Ensembl
MGI		 PMID:18545656 GO_REF:0000107 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in ISO (PMID:15313915) UniProt PMID:15313915 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G HINT1 histidine triad nucleotide binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:126,587,934...126,594,032
Ensembl chr 5:132,755,766...132,761,823 		JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424 		JBrowse link
G JMY junction mediating and regulatory protein, p53 cofactor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10518217) TreeGrafter
MGI		 PMID:10518217 GO_REF:0000118 NCBI chr 5:35,981,666...36,076,428
Ensembl chr 5:36,261,971...36,567,349 		JBrowse link
G LOC100979315 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)		 UniProt PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449 		JBrowse link
G MYBBP1A MYB binding protein 1a involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,593,741...4,610,203
Ensembl chr17:4,586,431...4,603,097 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,185,463...44,202,221
Ensembl chr17:49,060,030...49,076,115 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO (PMID:10733530) MGI PMID:10733530 NCBI chr 6:135,845,845...135,863,603
Ensembl chr 6:139,931,031...139,947,792 		JBrowse link
G PML PML nuclear body scaffold acts_upstream_of_or_within ISO (PMID:14992722) MGI PMID:14992722 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr13:59,821,614...59,829,671 JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr 4:138,969,157...138,972,730
Ensembl chr 4:150,626,392...150,629,961 		JBrowse link
G PPP1R13B protein phosphatase 1 regulatory subunit 13B involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:84,359,917...84,474,892
Ensembl chr14:104,168,873...104,232,974 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RRN3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of ISO (PMID:15989966) MGI PMID:15989966 NCBI chr16:13,664,478...13,700,942 JBrowse link
G RRP8 ribosomal RNA processing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,630,695...6,735,711
Ensembl chr11:6,415,003...6,418,414 		JBrowse link
G SHISA5 shisa family member 5 acts_upstream_of_or_within ISO (PMID:12135983) MGI PMID:12135983 NCBI chr 3:48,389,924...48,426,064
Ensembl chr 3:49,471,604...49,508,840 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12135983), (PMID:16107883)
(PMID:20434500)		 Ensembl
MGI		 PMID:12135983 PMID:16107883 PMID:20434500 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
G TP53BP2 tumor protein p53 binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:199,403,194...199,469,079
Ensembl chr 1:204,414,218...204,457,739 		JBrowse link
G WWOX WW domain containing oxidoreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11058590) Ensembl
MGI		 PMID:11058590 GO_REF:0000107 NCBI chr16:58,689,609...59,800,333
Ensembl chr16:78,125,302...79,231,546 		JBrowse link
G ZNF385B zinc finger protein 385B involved_in ISO (PMID:22945289) UniProt PMID:22945289 NCBI chr2B:66,696,635...67,115,011
Ensembl chr2B:184,400,205...184,726,522 		JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AEN apoptosis enhancing nuclease involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:67,237,871...67,321,808
Ensembl chr15:86,518,204...86,529,579 		JBrowse link
G ATAD5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15983387) Ensembl
MGI		 PMID:15983387 GO_REF:0000107 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G BBC3 BCL2 binding component 3 acts_upstream_of_or_within ISO (PMID:16151013) MGI PMID:16151013 NCBI chr19:44,203,517...44,215,860 JBrowse link
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16384933) MGI
Ensembl		 PMID:16384933 GO_REF:0000107 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005 		JBrowse link
G BRCA2 BRCA2 DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15735671)
(PMID:17476307)		 Ensembl
MGI		 PMID:15735671 PMID:17476307 GO_REF:0000107 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332 		JBrowse link
G CDIP1 cell death inducing p53 target 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17599062) MGI
TreeGrafter
Ensembl		 PMID:17599062 GO_REF:0000107 GO_REF:0000118 NCBI chr16:3,437,414...3,464,989
Ensembl chr16:4,604,954...4,632,724 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12952892) Ensembl
MGI		 PMID:12952892 GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CHEK2 checkpoint kinase 2 acts_upstream_of_or_within ISO (PMID:10710310) MGI PMID:10710310 NCBI chr22:9,757,038...9,811,171 JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149 		JBrowse link
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:21,241,325...21,260,321
Ensembl chr12:21,757,436...21,767,505 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22768269) Ensembl
MGI		 PMID:22768269 GO_REF:0000107 NCBI chr15:22,732,742...22,737,522
Ensembl chr15:40,821,759...40,827,070 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16537918) Ensembl
MGI
TreeGrafter		 PMID:16537918 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:88,579,603...88,627,988
Ensembl chr 1:123,633,134...123,677,714 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16537918) Ensembl
MGI
TreeGrafter		 PMID:16537918 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G IFI16 interferon gamma inducible protein 16 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14654789) MGI
Ensembl		 PMID:14654789 GO_REF:0000107 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424 		JBrowse link
G LOC100979315 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (PMID:10807576) MGI PMID:10807576 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449 		JBrowse link
G MSH2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10097137) Ensembl
MGI		 PMID:10097137 GO_REF:0000107 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator acts_upstream_of_or_within ISO (PMID:11896600) MGI PMID:11896600 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:177,063,775...177,067,714
Ensembl chr 1:181,367,976...181,368,359 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chr14:82,383,086...82,549,822
Ensembl chr14:102,206,396...102,372,978 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:17057733), (PMID:18056458) UniProt PMID:17057733 PMID:18056458 NCBI chr15:42,101,137...42,105,019
Ensembl chr15:60,397,131...60,400,643 		JBrowse link
G SHISA5 shisa family member 5 acts_upstream_of_or_within ISO (PMID:12135983) MGI PMID:12135983 NCBI chr 3:48,389,924...48,426,064
Ensembl chr 3:49,471,604...49,508,840 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SNW1 SNW domain containing 1 involved_in ISO (PMID:21460037) UniProt PMID:21460037 NCBI chr14:58,271,830...58,315,773
Ensembl chr14:77,472,387...77,517,315 		JBrowse link
G TMEM109 transmembrane protein 109 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20060811) Ensembl
MGI
TreeGrafter		 PMID:20060811 GO_REF:0000107 GO_REF:0000118 NCBI chr11:56,177,335...56,186,645
Ensembl chr11:59,617,802...59,627,349 		JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15735665) Ensembl
MGI		 PMID:15735665 GO_REF:0000107 NCBI chr 9:32,314,850...32,327,067
Ensembl chr 9:33,124,730...33,135,129 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14654789), (PMID:14744935)
(PMID:15983387)
(PMID:12135983)
(PMID:16286009)
(PMID:17476307)
(PMID:16777961)
(PMID:12952892)		 MGI
Ensembl		 PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17122775) Ensembl
MGI		 PMID:17122775 GO_REF:0000107 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104 		JBrowse link
G TP73 tumor protein p73 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15983387) Ensembl
MGI		 PMID:15983387 GO_REF:0000107 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206 		JBrowse link
G USP28 ubiquitin specific peptidase 28 involved_in ISO (PMID:16901786) UniProt PMID:16901786 NCBI chr11:108,676,566...108,754,372
Ensembl chr11:112,517,693...112,595,585 		JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16571598) Ensembl
MGI		 PMID:16571598 GO_REF:0000107 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC10 armadillo repeat containing 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:95,049,105...95,073,466
Ensembl chr 7:107,899,776...107,922,685 		JBrowse link
G CEP63 centrosomal protein 63 acts_upstream_of_or_within ISO (PMID:26158450) MGI PMID:26158450 NCBI chr 3:131,532,450...131,609,240
Ensembl chr 3:139,003,898...139,092,680 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) CAFA PMID:17310983 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G MDM4 MDM4 regulator of p53 involved_in ISO (MGI:2182884|PMID:12101245) UniProt PMID:12101245 MGI:2182884 NCBI chr 1:180,117,364...180,151,144
Ensembl chr 1:184,406,124...184,439,344 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PTTG1IP PTTG1 interacting protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24506068) MGI
Ensembl		 PMID:24506068 GO_REF:0000107 NCBI chr21:31,143,600...31,169,231
Ensembl chr21:44,438,136...44,459,586 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12858174) Ensembl
MGI		 PMID:12858174 GO_REF:0000107 NCBI chr 8:98,854,101...98,890,365
Ensembl chr 8:101,019,699...101,052,056 		JBrowse link
G RRN3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO (PMID:15989966) MGI PMID:15989966 NCBI chr16:13,664,478...13,700,942 JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) UniProt PMID:24523556 MGI:5553386 NCBI chr 1:119,224,304...119,267,986
Ensembl chr 1:88,077,420...88,121,056 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242 		JBrowse link
G BCL2L12 BCL2 like 12 acts_upstream_of_or_within ISO (PMID:20837658) MGI PMID:20837658 NCBI chr19:46,679,749...46,688,539 JBrowse link
G CD44 CD44 molecule (IN blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009 		JBrowse link
G CD74 CD74 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22768269) Ensembl
MGI		 PMID:22768269 GO_REF:0000107 NCBI chr15:22,732,742...22,737,522
Ensembl chr15:40,821,759...40,827,070 		JBrowse link
G KDM1A lysine demethylase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907 		JBrowse link
G MIF macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009 		JBrowse link
G MUC1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:118,025,599...118,028,045
Ensembl chr12:121,400,063...121,402,506 		JBrowse link
G ZNF385A zinc finger protein 385A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,353,975...34,376,172
Ensembl chr12:35,080,820...35,102,248 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16571598) Ensembl
MGI		 PMID:16571598 GO_REF:0000107 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF5A eukaryotic translation initiation factor 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,341,076...7,346,570
Ensembl chr17:7,327,363...7,333,270 		JBrowse link
G LOC134730372 small ribosomal subunit protein eS7 involved_in IEA Ensembl GO_REF:0000107
G MSX1 msh homeobox 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:4,935,600...4,939,079 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:3,593,350...3,599,106
Ensembl chr2A:3,512,079...3,517,785 		JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) UniProt PMID:24523556 MGI:5553386 NCBI chr 1:119,224,304...119,267,986
Ensembl chr 1:88,077,420...88,121,056 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) MGI PMID:17571083 NCBI chr17:35,286,699...35,288,429 JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100977427 large ribosomal subunit protein uL24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:56,616,749...56,617,299
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G STEAP3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:18617898) MGI PMID:18617898 NCBI chr2B:6,166,296...6,208,338
Ensembl chr2B:119,752,363...119,787,051 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:15983387) MGI PMID:15983387 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206 		JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940) MGI PMID:18302940 NCBI chr10:94,192,920...94,204,400
Ensembl chr10:97,686,121...97,697,238 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17571083) Ensembl
MGI		 PMID:17571083 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPK heterogeneous nuclear ribonucleoprotein K involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20673990) Ensembl
MGI		 PMID:20673990 GO_REF:0000107 NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIFAB TIFA inhibitor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32101751) Ensembl
MGI		 PMID:32101751 GO_REF:0000107 NCBI chr 5:130,836,697...130,846,050
Ensembl chr 5:136,983,040...136,983,525 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32101751) Ensembl
MGI		 PMID:32101751 GO_REF:0000107 NCBI chr12:26,533,441...26,682,964
Ensembl chr12:26,808,337...26,954,099 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      signal transduction 5440
        intracellular signal transduction 2609
          intrinsic apoptotic signaling pathway 327
            intrinsic apoptotic signaling pathway by p53 class mediator 87
              intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator + 46
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
              negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 22
              positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 11
              regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 37
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        signaling 5935
          signal transduction 5440
            intracellular signal transduction 2609
              intrinsic apoptotic signaling pathway 327
                intrinsic apoptotic signaling pathway by p53 class mediator 87
                  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator + 46
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
                  negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 22
                  positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 11
                  regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 37
paths to the root