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ONTOLOGY REPORT - ANNOTATIONS

Term:signal transduction by p53 class mediator
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Accession:GO:0072331 term browser browse the term
Definition:An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.


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signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO UniProtKB:P04637 (MGI:5318033|PMID:12135612) RGD PMID:12135612 MGI:5318033 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:28294157), (PMID:29229990) RGD PMID:28294157 PMID:29229990 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Atrx ATRX, chromatin remodeler involved_in ISS
ISO		 GO_REF:0000024
(MGI:5568153|PMID:24651726)		 UniProt
RGD		 PMID:24651726 GO_REF:0000024 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448499|PMID:22385964)		 UniProt
RGD		 PMID:22385964 GO_REF:0000024 MGI:5448499 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G E2f7 E2F transcription factor 7 involved_in ISO
IEA
ISS		 (PMID:22802528)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22802528 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO (MGI:3057054|PMID:15383658) RGD PMID:15383658 MGI:3057054 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:14660608) RGD PMID:14660608 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mif macrophage migration inhibitory factor acts_upstream_of_or_within ISO MGI:2673280 (MGI:2670239|PMID:12878730) RGD PMID:12878730 MGI:2670239 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:16507995) RGD PMID:16507995 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO
IEA		 (PMID:9766676)
GO_REF:0000107		 RGD
Ensembl		 PMID:9766676 GO_REF:0000107 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:15456759), (PMID:17690115) RGD PMID:15456759 PMID:17690115 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D acts_upstream_of_or_within ISO (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:18692468)
(MGI:3808916|PMID:18692468)		 RGD PMID:18692468 MGI:3808916 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:15149599), (PMID:20160708)
MGI:106184|MGI:109337 (MGI:2156961|PMID:11790307), (MGI:3032953|PMID:11884608), (MGI:3603875|PMID:16199867), (MGI:3714678|PMID:17476307)		 RGD PMID:11790307 PMID:11884608 PMID:15149599 PMID:16199867 PMID:17476307 More... MGI:2156961 MGI:3032953 MGI:3603875 MGI:3714678 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:20096447)		 UniProt
RGD		 PMID:20096447 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in IBA
ISO		 PMID:21873635
(PMID:21726810)		 RGD PMID:21726810 PMID:21873635 RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23235459)		 UniProt
RGD		 PMID:23235459 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO
IEA		 (PMID:16213212)
GO_REF:0000107
(MGI:5882892|PMID:16213212)		 RGD
Ensembl		 PMID:16213212 GO_REF:0000107 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)		 RGD PMID:16107883 PMID:16213212 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1930616 (MGI:84760|PMID:8738145)		 Ensembl
RGD		 PMID:8738145 GO_REF:0000107 MGI:84760 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)		 RGD
Ensembl		 PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:16387653) RGD PMID:16387653 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14966270)		 UniProt
RGD		 PMID:14966270 GO_REF:0000024 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in IBA
ISO		 PMID:21873635
(PMID:15042092)		 RGD PMID:15042092 PMID:21873635 RGD:13792537 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:16213212), (PMID:16479015), (PMID:7958916)
(MGI:1354114|PMID:10710310)		 RGD PMID:7958916 PMID:10710310 PMID:16213212 PMID:16479015 MGI:1354114 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:1344924|PMID:10479688) RGD PMID:10479688 MGI:1344924 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (PMID:15102863) RGD PMID:15102863 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp6 caspase 6 involved_in ISO
ISS		 (PMID:22858542)
GO_REF:0000024		 RGD
UniProt		 PMID:22858542 GO_REF:0000024 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of ISO MGI:98834 (MGI:5662131|PMID:26158450) RGD PMID:26158450 MGI:5662131 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within ISO (MGI:1927703|PMID:11095619) RGD PMID:11095619 MGI:1927703 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 acts_upstream_of_or_within ISO (MGI:1927703|PMID:11095619) RGD PMID:11095619 MGI:1927703 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G Eda2r ectodysplasin A2 receptor acts_upstream_of_or_within ISO MGI:98834 (MGI:4454200|PMID:20434500) RGD PMID:20434500 MGI:4454200 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:15313915)
GO_REF:0000024		 RGD
UniProt		 PMID:15313915 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 involved_in ISO
ISS		 (PMID:16835243)
GO_REF:0000024		 RGD
UniProt		 PMID:16835243 GO_REF:0000024 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1891484|PMID:10518217)		 RGD PMID:10518217 PMID:21873635 MGI:1891484, RGD:13792537 NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006 		JBrowse link
G Mybbp1a MYB binding protein 1a involved_in ISO (PMID:21471221) RGD PMID:21471221 NCBI chr10:57,056,913...57,067,263
Ensembl chr10:57,056,874...57,067,255 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO (PMID:22123926) RGD PMID:22123926 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO (MGI:1929912|PMID:10733530) RGD PMID:10733530 MGI:1929912 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)		 RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO (MGI:3034149|PMID:14992722) RGD PMID:14992722 MGI:3034149 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5825431|PMID:17145718)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17145718 GO_REF:0000024 GO_REF:0000107 MGI:5825431 NCBI chr15:81,255,566...81,260,057
Ensembl chr15:81,257,781...81,259,728 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5825431|PMID:17145718)		 UniProt
RGD		 PMID:17145718 GO_REF:0000024 MGI:5825431 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Ppp1r13b protein phosphatase 1, regulatory subunit 13B involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr 6:130,890,679...130,963,845
Ensembl chr 6:130,890,679...130,963,330 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of ISO MGI:3584037 (MGI:3583493|PMID:15989966) RGD PMID:15989966 MGI:3583493 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISO (PMID:21471221) RGD PMID:21471221 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331 		JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (MGI:2183272|PMID:12135983) RGD PMID:12135983 MGI:2183272 NCBI chr 8:109,691,476...109,706,409
Ensembl chr 8:109,691,522...109,706,408 		JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO
ISS		 (PMID:11430832)
GO_REF:0000024		 RGD
UniProt		 PMID:11430832 GO_REF:0000024 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:12172011), (PMID:16322561), (PMID:17310983)
MGI:2442860 (MGI:2183272|PMID:12135983), (MGI:3589512|PMID:16107883), (MGI:4454200|PMID:20434500)
(MGI:5883206|PMID:22262176)		 RGD PMID:12135983 PMID:12172011 PMID:16107883 PMID:16322561 PMID:17310983 More... MGI:2183272 MGI:3589512 MGI:4454200 MGI:5883206 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO MGI:98834 (MGI:1930321|PMID:11058590) RGD PMID:11058590 MGI:1930321 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
G Zfp385b zinc finger protein 385B involved_in ISO (PMID:22945289) RGD PMID:22945289 NCBI chr 3:62,355,182...62,640,417
Ensembl chr 3:62,355,196...62,640,510 		JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:18264133)
PMID:21873635		 UniProt
RGD		 PMID:18264133 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:1336991|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17403783)		 UniProt
Ensembl
RGD		 PMID:17403783 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bbc3 Bcl-2 binding component 3 acts_upstream_of_or_within ISO MGI:2681654 (MGI:3603103|PMID:16151013) RGD PMID:16151013 MGI:3603103 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2429691|MGI:3052655|MGI:98834 (MGI:3579926|PMID:15735671), (MGI:3714678|PMID:17476307)		 Ensembl
RGD		 PMID:15735671 PMID:17476307 GO_REF:0000107 MGI:3579926 MGI:3714678 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdip1 cell death-inducing p53 target 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:17599062)
PMID:21873635		 RGD PMID:17599062 PMID:21873635 RGD:13792537 NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:1933751 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5298149|PMID:21896779)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21896779 GO_REF:0000024 GO_REF:0000107 MGI:5298149 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in ISO (PMID:17349958) RGD PMID:17349958 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:17403783) RGD PMID:17403783 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
MGI:1314872|MGI:98834 (MGI:3619785|PMID:16537918)
GO_REF:0000107		 RGD
Ensembl		 PMID:16537918 PMID:21873635 GO_REF:0000107 MGI:3619785, RGD:13792537 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:1314872|MGI:98834 (MGI:3619785|PMID:16537918) RGD PMID:16537918 MGI:3619785 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98834 (MGI:1334080|PMID:10097137)		 Ensembl
RGD		 PMID:10097137 GO_REF:0000107 MGI:1334080 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator acts_upstream_of_or_within ISO MGI:3784016 (MGI:3784021|PMID:11896600) RGD PMID:11896600 MGI:3784021 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 involved_in ISO
ISS
IBA		 (PMID:19203586)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:19203586 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (MGI:1858284|PMID:10807576) RGD PMID:10807576 MGI:1858284 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:17057733), (PMID:18056458) RGD PMID:17057733 PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (MGI:2183272|PMID:12135983) RGD PMID:12135983 MGI:2183272 NCBI chr 8:109,691,476...109,706,409
Ensembl chr 8:109,691,522...109,706,408 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20100829) RGD PMID:20100829 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:21460037) RGD PMID:21460037 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Tmem109 transmembrane protein 109 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:4453832 (MGI:4437179|PMID:20060811)		 RGD PMID:20060811 PMID:21873635 MGI:4437179, RGD:13792537 NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215 		JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase acts_upstream_of_or_within ISO (MGI:3578084|PMID:15735665) RGD PMID:15735665 MGI:3578084 NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (MGI:4944151|PMID:20818388), (MGI:5882892|PMID:16213212)
(PMID:14654789), (PMID:14744935)
(PMID:16213212), (PMID:17403783)
MGI:109337|MGI:1096393|MGI:1336991|MGI:1857263|MGI:1926340|MGI:2442925 (MGI:2183272|PMID:12135983), (MGI:2675761|PMID:12952892), (MGI:3584078|PMID:15983387), (MGI:3652689|PMID:16777961), (MGI:3690827|PMID:16286009), (MGI:3714678|PMID:17476307)		 RGD PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... MGI:2183272 MGI:2675761 MGI:3584078 MGI:3652689 MGI:3690827 MGI:3714678 MGI:4944151 MGI:5882892 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934269 (MGI:3693137|PMID:17122775) RGD PMID:17122775 MGI:3693137 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 involved_in
acts_upstream_of		 ISO (PMID:18174154), (PMID:19490146)
MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387)		 RGD PMID:15983387 PMID:18174154 PMID:19490146 MGI:3584078 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO
ISS		 (PMID:16901786)
GO_REF:0000024		 RGD
UniProt		 PMID:16901786 GO_REF:0000024 NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229 		JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:98834|MGI:99702 (MGI:3654719|PMID:16571598)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:3690285|PMID:17045821)
(PMID:17045821)
PMID:21873635		 BHF-UCL
RGD		 PMID:17045821 PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4838949|PMID:20167603)		 Ensembl
RGD		 PMID:20167603 GO_REF:0000107 MGI:4838949 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISO
ISS		 (PMID:29295817)
GO_REF:0000024		 RGD
UniProt		 PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:10360174), (PMID:9529249) RGD PMID:9529249 PMID:10360174 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16023600)		 UniProt
RGD		 PMID:16023600 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:5433829|PMID:21183956) RGD PMID:21183956 MGI:5433829 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:11672523) RGD PMID:11672523 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (MGI:5050389|PMID:20817677) RGD PMID:20817677 MGI:5050389 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in IBA
ISO		 PMID:21873635
(PMID:17904127)		 RGD PMID:17904127 PMID:21873635 RGD:13792537 NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (MGI:5662131|PMID:26158450) RGD PMID:26158450 MGI:5662131 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (MGI:2182884|PMID:12101245) RGD PMID:12101245 MGI:2182884 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18829576) RGD PMID:18829576 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:23985028) RGD PMID:23985028 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within ISO MGI:2672883 (MGI:2670318|PMID:12858174) RGD PMID:12858174 MGI:2670318 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO MGI:3584037 (MGI:3583493|PMID:15989966) RGD PMID:15989966 MGI:3583493 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bcl2l12 Bcl2 like 12 acts_upstream_of_or_within ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
ISS
IBA		 (PMID:17045821)
GO_REF:0000024
(MGI:3690285|PMID:17045821)
PMID:21873635		 RGD
BHF-UCL		 PMID:17045821 PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29295817)		 UniProt
RGD		 PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:2152474|PMID:11672522) RGD PMID:11672522 MGI:2152474 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:98834|MGI:99702 (MGI:3654719|PMID:16571598)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571598 GO_REF:0000107 MGI:3654719 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
negative regulation of signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within ISO (MGI:5438719|PMID:22768269) RGD PMID:22768269 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:16173922) RGD PMID:16173922 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (MGI:5897550|PMID:21804542) RGD PMID:21804542 MGI:5897550 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:17121812)
GO_REF:0000024		 RGD
UniProt		 PMID:17121812 GO_REF:0000024 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G RGD1309748 similar to CG4768-PA involved_in ISO (PMID:33660365) RGD PMID:33660365 NCBI chr10:6,746,037...6,774,992
Ensembl chr10:6,746,048...6,774,992 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISO
ISS		 (PMID:17121812)
GO_REF:0000024		 RGD
UniProt		 PMID:17121812 GO_REF:0000024 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:5433829|PMID:21183956) RGD PMID:21183956 MGI:5433829 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:20599664) RGD PMID:20599664 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) RGD PMID:9925639 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335) RGD PMID:16269335 MGI:5297787 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19197340)		 UniProt
RGD		 PMID:19197340 GO_REF:0000024 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)		 RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:15251430) RGD PMID:15251430 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO
IEA		 (PMID:16213212)
GO_REF:0000107		 RGD
Ensembl		 PMID:16213212 GO_REF:0000107 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (PMID:17700068) RGD PMID:17700068 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (MGI:5883206|PMID:22262176) RGD PMID:22262176 MGI:5883206 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) RGD PMID:24523556 MGI:5553386 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) RGD PMID:17571083 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO
IEA		 (PMID:16213212)
GO_REF:0000107
(MGI:5882892|PMID:16213212)		 RGD
Ensembl		 PMID:16213212 GO_REF:0000107 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
positive regulation of signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16173922)		 UniProt
RGD		 PMID:16173922 GO_REF:0000024 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:16173922) RGD PMID:16173922 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3711389|PMID:17289567)		 UniProt
RGD		 PMID:17289567 GO_REF:0000024 MGI:3711389 NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:22948151) RGD PMID:22948151 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3717518|PMID:10910364) RGD PMID:10910364 MGI:3717518 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897550|PMID:21804542)		 UniProt
RGD		 PMID:21804542 GO_REF:0000024 MGI:5897550 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpl23 ribosomal protein L23 involved_in ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl37 ribosomal protein L37 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr 2:54,215,352...54,217,429
Ensembl chr 2:54,215,469...54,217,442 		JBrowse link
G Rpl37l1 ribosomal protein L37-like1 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr10:61,033,799...61,034,157
Ensembl chr10:61,033,797...61,034,168 		JBrowse link
G Rps15 ribosomal protein S15 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450 		JBrowse link
G Rps20 ribosomal protein S20 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr 5:16,819,313...16,820,475
Ensembl chr 5:16,819,304...16,820,475 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G Kmt5a lysine methyltransferase 5A involved_in ISO
IBA		 (PMID:17707234)
PMID:21873635		 RGD PMID:17707234 PMID:21873635 RGD:13792537 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO MGI:98834 (MGI:3603875|PMID:16199867) RGD PMID:16199867 MGI:3603875 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G RGD1561318 similar to SET domain-containing protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Smyd2 SET and MYND domain containing 2 involved_in ISO
ISS		 (PMID:17108971)
GO_REF:0000024		 RGD
UniProt		 PMID:17108971 GO_REF:0000024 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:3789238|PMID:16079796), (MGI:5013521|PMID:21522133) RGD PMID:16079796 PMID:21522133 MGI:3789238 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops3 COP9 signalosome subunit 3 involved_in ISO (PMID:15861129) RGD PMID:15861129 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (MGI:3796961|PMID:18302940) RGD PMID:18302940 MGI:3796961 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3818156|PMID:17571083) RGD PMID:17571083 MGI:3818156 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of_or_within ISO (MGI:4881379|PMID:20673990) RGD PMID:20673990 MGI:4881379 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
regulation of signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bop1 BOP1 ribosomal biogenesis factor involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931 		JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 acts_upstream_of_or_within ISO (MGI:3764736|PMID:18022393) RGD PMID:18022393 MGI:3764736 NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077 		JBrowse link
G Mlf1 myeloid leukemia factor 1 acts_upstream_of_positive_effect ISO UniProtKB:Q9UNS2 (PMID:15861129) RGD PMID:15861129 NCBI chr 2:151,648,492...151,681,654
Ensembl chr 2:151,648,511...151,681,652 		JBrowse link
G Nop2 NOP2 nucleolar protein involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597), (PMID:24120868), (PMID:24556985), (PMID:27829214) RGD PMID:22522597 PMID:24120868 PMID:24556985 PMID:27829214 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Pak1ip1 PAK1 interacting protein 1 involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr17:23,742,217...23,753,325
Ensembl chr17:23,741,414...23,753,324 		JBrowse link
G Prmt6 protein arginine methyltransferase 6 acts_upstream_of_or_within ISO (MGI:5504576|PMID:22904064) RGD PMID:22904064 MGI:5504576 NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648 		JBrowse link
G Rpf2 ribosome production factor 2 homolog involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpl5 ribosomal protein L5 involved_in ISO (PMID:24120868) RGD PMID:24120868 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog involved_in ISS
ISO		 GO_REF:0000024
(PMID:24120868)		 UniProt
RGD		 PMID:24120868 GO_REF:0000024 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140 		JBrowse link
G Trim24 tripartite motif-containing 24 acts_upstream_of_or_within ISO MGI:98834 (MGI:3851860|PMID:19556538) RGD PMID:19556538 MGI:3851860 NCBI chr 4:66,664,864...66,717,244
Ensembl chr 4:66,566,686...66,717,241 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    signaling 7399
      signal transduction 6838
        intracellular signal transduction 2675
          signal transduction by p53 class mediator 156
            DNA damage response, signal transduction by p53 class mediator + 73
            intrinsic apoptotic signaling pathway by p53 class mediator + 84
            negative regulation of signal transduction by p53 class mediator + 35
            positive regulation of signal transduction by p53 class mediator + 34
            regulation of signal transduction by p53 class mediator + 89
Path 2
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of biological process 12644
        regulation of cellular process 11961
          signal transduction 6838
            intracellular signal transduction 2675
              signal transduction by p53 class mediator 156
                DNA damage response, signal transduction by p53 class mediator + 73
                intrinsic apoptotic signaling pathway by p53 class mediator + 84
                negative regulation of signal transduction by p53 class mediator + 35
                positive regulation of signal transduction by p53 class mediator + 34
                regulation of signal transduction by p53 class mediator + 89
paths to the root