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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,923,383...1,958,160
Ensembl chrNW_004936694:1,930,621...1,957,179
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004936905:76,781...128,995 JBrowse link
G Umod uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:5,833,391...5,846,021
Ensembl chrNW_004936501:5,833,391...5,846,164
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:3,858,344...3,881,985
Ensembl chrNW_004936544:3,858,344...3,882,106
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:7,146,997...7,160,369
Ensembl chrNW_004936478:7,147,027...7,160,401
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:3,858,344...3,881,985
Ensembl chrNW_004936544:3,858,344...3,882,106
JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214
JBrowse link
G Pax8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
G Umod uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:5,833,391...5,846,021
Ensembl chrNW_004936501:5,833,391...5,846,164
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004936905:76,781...128,995 JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,923,383...1,958,160
Ensembl chrNW_004936694:1,930,621...1,957,179
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:9693135) UniProt PMID:9693135 NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:19060336) MGI PMID:19060336 NCBI chrNW_004936629:3,869,976...3,907,932
Ensembl chrNW_004936629:3,869,523...3,909,808
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:11,888,024...11,895,058
Ensembl chrNW_004936493:11,888,024...11,895,058
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214
JBrowse link
G Pax8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21212101) Ensembl
MGI
PMID:21212101 GO_REF:0000107 NCBI chrNW_004936501:128,386...132,648
Ensembl chrNW_004936501:127,703...132,704
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21212101) Ensembl
MGI
PMID:21212101 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936711:640,002...642,580
Ensembl chrNW_004936711:639,905...642,622
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:1,045,496...1,047,865
Ensembl chrNW_004936737:1,046,613...1,047,950
JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936540:5,752,319...5,846,074
Ensembl chrNW_004936540:5,752,197...5,845,159
JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16886065) Ensembl
MGI
PMID:16886065 GO_REF:0000107 NCBI chrNW_004936529:826,178...841,304
Ensembl chrNW_004936529:826,142...841,337
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:9,496,083...9,516,086
Ensembl chrNW_004936481:9,496,127...9,515,534
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:7733320 RGD:2326090 NCBI chrNW_004936551:594,647...626,016
Ensembl chrNW_004936551:591,695...626,056
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:7,146,997...7,160,369
Ensembl chrNW_004936478:7,147,027...7,160,401
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:7,146,997...7,160,369
Ensembl chrNW_004936478:7,147,027...7,160,401
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936483:15,563,540...15,582,521
Ensembl chrNW_004936483:15,563,528...15,589,601
JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936478:7,146,997...7,160,369
Ensembl chrNW_004936478:7,147,027...7,160,401
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936469:10,245,001...10,438,933
Ensembl chrNW_004936469:10,244,881...10,438,935
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,923,383...1,958,160
Ensembl chrNW_004936694:1,930,621...1,957,179
JBrowse link
G Slc15a1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936472:11,669,206...11,716,303
Ensembl chrNW_004936472:11,669,206...11,716,303
JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936536:8,280,537...8,316,011
Ensembl chrNW_004936536:8,280,448...8,316,064
JBrowse link
G Slc22a1 solute carrier family 22 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745
JBrowse link
G Slc22a6 solute carrier family 22 member 6 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936581:348,719...356,246
Ensembl chrNW_004936581:349,057...356,059
JBrowse link
G Slc2a5 solute carrier family 2 member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936623:3,226,533...3,249,909
Ensembl chrNW_004936623:3,226,515...3,249,914
JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004936598:3,391,587...3,713,629
Ensembl chrNW_004936598:3,391,575...3,713,635
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umod uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:5,833,391...5,846,021
Ensembl chrNW_004936501:5,833,391...5,846,164
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214
JBrowse link
G Pax8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214
JBrowse link
G Pax8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat4 FAT atypical cadherin 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23974041) MGI
Ensembl
PMID:23974041 GO_REF:0000107 NCBI chrNW_004936662:3,537,917...3,704,012
Ensembl chrNW_004936662:3,537,925...3,690,877
JBrowse link
G Lif LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936904:410,043...413,256
Ensembl chrNW_004936904:410,043...413,257
JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214
JBrowse link
G Pax8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23974041) MGI
Ensembl
PMID:23974041 GO_REF:0000107 NCBI chrNW_004936758:101,629...225,496
Ensembl chrNW_004936758:101,620...225,525
JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chrNW_004936551:5,638,383...5,740,523
Ensembl chrNW_004936551:5,634,751...5,740,567
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17411
    developmental process 6424
      anatomical structure development 6039
        nephron development 179
          nephron epithelium development 134
            metanephric nephron epithelium development 31
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 0
              metanephric nephron tubule development + 27
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 17411
    developmental process 6424
      anatomical structure development 6039
        multicellular organism development 4888
          system development 4254
            renal system development 397
              kidney development 383
                kidney epithelium development 168
                  nephron epithelium development 134
                    metanephric nephron epithelium development 31
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 0
                      metanephric nephron tubule development + 27
                      metanephric short descending thin limb development 0
paths to the root