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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.



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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,849,579...39,899,455
Ensembl chr 3:39,849,609...39,899,455
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932
JBrowse link
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:49,804,112...49,807,730
Ensembl chr 3:49,806,161...49,807,666
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:46,701,276...46,723,548
Ensembl chr 4:46,701,045...46,725,197
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:49,804,112...49,807,730
Ensembl chr 3:49,806,161...49,807,666
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:46,701,276...46,723,548
Ensembl chr 4:46,701,045...46,725,197
JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,849,579...39,899,455
Ensembl chr 3:39,849,609...39,899,455
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:9693135) UniProt PMID:9693135 Ensembl chr 5:8,986,462...9,007,435 JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:49,804,112...49,807,730
Ensembl chr 3:49,806,161...49,807,666
JBrowse link
G WNT7B Wnt family member 7B acts_upstream_of_or_within ISO (PMID:19060336) MGI PMID:19060336 NCBI chr 5:3,521,412...3,572,322
Ensembl chr 5:3,521,288...3,572,314
JBrowse link
metanephric macula densa development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:49,804,112...49,807,730
Ensembl chr 3:49,806,161...49,807,666
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:118,368,471...118,765,107
Ensembl chr 3:118,757,920...118,765,102
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969
JBrowse link
G SOX8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21212101) Ensembl
MGI
PMID:21212101 GO_REF:0000107 NCBI chr 3:40,825,151...40,830,085
Ensembl chr 3:40,825,157...40,830,736
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
(PMID:21212101) Ensembl
MGI
UniProt
PMID:21212101 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,725...131,138,237
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:64,409,110...64,410,541
Ensembl chr 6:64,408,956...64,410,881
JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:32,871,837...32,979,150
Ensembl chr 2:32,871,871...32,979,148
JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16886065) Ensembl
MGI
PMID:16886065 GO_REF:0000107 NCBI chr13:31,738,282...31,750,623
Ensembl chr13:31,738,286...31,750,833
JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:121,217,734...121,236,214
Ensembl chr 9:121,218,369...121,236,430
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:7733320 RGD:2326090 NCBI chr 9:36,525,266...36,545,634
Ensembl chr 9:36,525,261...36,545,633
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chr 7:55,351,081...55,373,856
Ensembl chr 7:55,351,087...55,373,881
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:30645697 RGD:155631307 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746
JBrowse link
G LRP2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,849,579...39,899,455
Ensembl chr 3:39,849,609...39,899,455
JBrowse link
G SLC15A1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr13:138,595,942...138,634,473
Ensembl chr13:138,595,973...138,632,675
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 1:7,340,442...7,365,543
Ensembl chr 1:7,340,126...7,365,520
JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 2:8,809,547...8,817,124
Ensembl chr 2:8,802,349...8,817,337
JBrowse link
G SLC2A5 solute carrier family 2 member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 6:69,507,829...69,535,794
Ensembl chr 6:69,507,830...69,535,371
JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 8:67,768,955...68,177,213
Ensembl chr 8:67,706,874...68,177,212
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:49,804,112...49,807,730
Ensembl chr 3:49,806,161...49,807,666
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969
JBrowse link
negative regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STAT1 signal transducer and activator of transcription 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969
JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS UniProt GO_REF:0000024 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAT4 FAT atypical cadherin 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr 8:99,141,967...99,312,131
Ensembl chr 8:99,148,496...99,310,519
JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,221,540...47,239,513
Ensembl chr14:47,221,560...47,238,749
JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr13:89,742,980...89,889,547
Ensembl chr13:89,742,886...89,889,187
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,226...32,925,606
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18932
    developmental process 6758
      anatomical structure development 6342
        nephron development 187
          nephron epithelium development 141
            metanephric nephron epithelium development 32
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 1
              metanephric nephron tubule development + 28
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 18932
    developmental process 6758
      anatomical structure development 6342
        multicellular organism development 5123
          system development 4469
            renal system development 406
              kidney development 393
                kidney epithelium development 177
                  nephron epithelium development 141
                    metanephric nephron epithelium development 32
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 1
                      metanephric nephron tubule development + 28
                      metanephric short descending thin limb development 0
paths to the root