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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.



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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEP (PMID:11891195) UniProt PMID:11891195 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEP (PMID:11891195) UniProt PMID:11891195 NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
JBrowse link
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PAX8 paired box 8 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEP (PMID:11891195) UniProt PMID:11891195 NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEP (PMID:11891195) UniProt PMID:11891195 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:9693135) UniProt PMID:9693135 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
G WNT7B Wnt family member 7B involved_in
acts_upstream_of_or_within
ISS
ISO
(PMID:19060336) UniProt
MGI
PMID:19060336 GO_REF:0000024 NCBI chr22:45,920,366...45,977,162
Ensembl chr22:45,920,366...45,977,162
JBrowse link
metanephric macula densa development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:19,344,874...19,358,623
Ensembl chr 2:19,351,485...19,358,623
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G SOX8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:21212101) UniProt
MGI
Ensembl
PMID:21212101 GO_REF:0000024 GO_REF:0000107 NCBI chr16:981,770...986,979
Ensembl chr16:981,444...986,979
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
(PMID:21212101) Ensembl
MGI
UniProt
PMID:21212101 GO_REF:0000024 GO_REF:0000107 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,528,745...2,530,263
Ensembl chr 1:2,528,745...2,530,263
JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790
JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16886065) Ensembl
MGI
PMID:16886065 GO_REF:0000107 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118
JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEP (PMID:11786407) UniProt PMID:11786407 NCBI chr 1:179,550,539...179,575,948
Ensembl chr 1:179,550,539...179,575,952
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in ISO
IEA
RGD
Ensembl
PMID:7733320 GO_REF:0000107 RGD:2326090 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:30645697 RGD:155631307 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G LRP2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEP (PMID:11891195) UniProt PMID:11891195 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G SLC15A1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr13:98,683,801...98,752,672
Ensembl chr13:98,683,801...98,752,672
JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188
JBrowse link
G SLC22A1 solute carrier family 22 member 1 involved_in ISO
IEA
RGD
Ensembl
PMID:30645697 GO_REF:0000107 RGD:155631307 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
JBrowse link
G SLC22A6 solute carrier family 22 member 6 involved_in ISO
IEA
RGD
Ensembl
PMID:30645697 GO_REF:0000107 RGD:155631307 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967
JBrowse link
G SLC2A5 solute carrier family 2 member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478
JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
negative regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STAT1 signal transducer and activator of transcription 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAT4 FAT atypical cadherin 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932
JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IDA (PMID:20624457) BHF-UCL PMID:20624457 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PAX8 paired box 8 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20482
    developmental process 7685
      anatomical structure development 7068
        nephron development 190
          nephron epithelium development 144
            metanephric nephron epithelium development 33
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 1
              metanephric nephron tubule development + 29
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 20482
    developmental process 7685
      anatomical structure development 7068
        multicellular organism development 5681
          system development 4955
            renal system development 417
              kidney development 404
                kidney epithelium development 180
                  nephron epithelium development 144
                    metanephric nephron epithelium development 33
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 1
                      metanephric nephron tubule development + 29
                      metanephric short descending thin limb development 0
paths to the root