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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.



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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438
JBrowse link
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:35,551,836...35,572,985
Ensembl chr29:35,552,436...35,572,925
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:35,551,836...35,572,985
Ensembl chr29:35,552,436...35,572,925
JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:9693135) UniProt PMID:9693135 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684
JBrowse link
G WNT7B Wnt family member 7B acts_upstream_of_or_within ISO (PMID:19060336) MGI PMID:19060336 NCBI chr10:20,160,916...20,208,786
Ensembl chr10:20,160,206...20,243,160
JBrowse link
metanephric macula densa development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
G SOX8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21212101) Ensembl
MGI
PMID:21212101 GO_REF:0000107 NCBI chr 6:39,667,941...39,672,716
Ensembl chr 6:39,668,232...39,672,638
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:21212101) UniProt
MGI
Ensembl
PMID:21212101 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388
JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:47,952,019...47,995,530
Ensembl chr21:47,952,890...47,996,288
JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16886065) Ensembl
MGI
PMID:16886065 GO_REF:0000107 NCBI chr20:40,036,967...40,062,628
Ensembl chr20:40,050,157...40,062,523
JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,347,526...20,375,975
Ensembl chr 7:20,354,134...20,374,020
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:7733320 RGD:2326090 NCBI chr 5:24,361,301...24,379,807
Ensembl chr 5:24,361,301...24,379,812
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chr 3:52,764,418...52,779,516
Ensembl chr 3:52,764,418...52,779,746
JBrowse link
G AQP1 aquaporin 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
G LOC489640 solute carrier family 2, facilitated glucose transporter member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 5:62,417,234...62,444,903
Ensembl chr 5:62,417,591...62,442,922
JBrowse link
G LRP2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr36:13,910,450...14,107,081
Ensembl chr36:13,911,865...14,107,546
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503
JBrowse link
G SLC15A1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr22:48,777,627...48,827,533
Ensembl chr22:48,777,630...48,827,533
JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr33:25,154,415...25,190,715
Ensembl chr33:25,154,448...25,189,929
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 1:49,268,978...49,296,522 JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO RGD PMID:30645697 RGD:155631307 NCBI chr18:53,736,669...53,745,001
Ensembl chr18:53,736,959...53,744,396
JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chr13:60,375,215...60,670,664
Ensembl chr13:60,328,136...60,666,728
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684
JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS UniProt GO_REF:0000024 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAT4 FAT atypical cadherin 4 acts_upstream_of_or_within ISO (PMID:23974041) MGI PMID:23974041 NCBI chr19:15,157,595...15,332,821
Ensembl chr19:15,158,922...15,332,045
JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851
JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr23:44,277,707...44,409,911
Ensembl chr23:44,278,557...44,410,007
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23974041) Ensembl
MGI
PMID:23974041 GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22100
    developmental process 6892
      anatomical structure development 6454
        nephron development 190
          nephron epithelium development 143
            metanephric nephron epithelium development 32
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 1
              metanephric nephron tubule development + 28
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 22100
    developmental process 6892
      anatomical structure development 6454
        multicellular organism development 5226
          system development 4549
            renal system development 415
              kidney development 401
                kidney epithelium development 180
                  nephron epithelium development 143
                    metanephric nephron epithelium development 32
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 1
                      metanephric nephron tubule development + 28
                      metanephric short descending thin limb development 0
paths to the root