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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004955442:15,132,555...15,178,377
Ensembl chrNW_004955442:15,145,640...15,178,377
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004955474:1,831,221...1,868,170
Ensembl chrNW_004955474:1,833,701...1,868,817
JBrowse link
G Umod uromodulin involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955442:3,986,936...4,001,155
Ensembl chrNW_004955442:3,985,308...3,999,598
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955417:6,944,300...6,969,341
Ensembl chrNW_004955417:6,942,900...6,969,502
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955417:6,944,300...6,969,341
Ensembl chrNW_004955417:6,942,900...6,969,502
JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796
JBrowse link
G Umod uromodulin involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955442:3,986,936...4,001,155
Ensembl chrNW_004955442:3,985,308...3,999,598
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004955474:1,831,221...1,868,170
Ensembl chrNW_004955474:1,833,701...1,868,817
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004955442:15,132,555...15,178,377
Ensembl chrNW_004955442:15,145,640...15,178,377
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:9693135) UniProt PMID:9693135 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:19060336) MGI PMID:19060336 NCBI chrNW_004955413:30,146,185...30,185,693
Ensembl chrNW_004955413:30,144,869...30,181,791
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (PMID:18835385) UniProt PMID:18835385 NCBI chrNW_004955469:1,954,470...1,961,344
Ensembl chrNW_004955469:1,953,370...1,961,390
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796
JBrowse link
G Sox8 SRY-box transcription factor 8 acts_upstream_of_or_within ISO (PMID:21212101) MGI PMID:21212101 NCBI chrNW_004955442:16,236,286...16,241,093
Ensembl chrNW_004955442:16,236,232...16,241,152
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:21212101) MGI PMID:21212101 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in ISO (PMID:15465493) UniProt PMID:15465493 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (PMID:15465493) UniProt PMID:15465493 NCBI chrNW_004955486:8,700,212...8,701,581
Ensembl chrNW_004955486:8,700,162...8,701,748
JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (PMID:21523854) UniProt PMID:21523854 NCBI chrNW_004955476:6,611,102...6,629,294
Ensembl chrNW_004955476:6,610,103...6,629,264
JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 acts_upstream_of_or_within ISO (PMID:16886065) MGI PMID:16886065 NCBI chrNW_004955532:1,115,412...1,127,264
Ensembl chrNW_004955532:1,115,087...1,127,455
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin involved_in ISO (PMID:11786407) UniProt PMID:11786407 NCBI chrNW_004955406:18,862,054...18,885,214
Ensembl chrNW_004955406:18,863,446...18,885,279
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:7733320 RGD:2326090 NCBI chrNW_004955412:10,350,088...10,369,806
Ensembl chrNW_004955412:10,349,593...10,369,806
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955416:15,415,981...15,442,032
Ensembl chrNW_004955416:15,424,932...15,444,075
JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955449:5,155,109...5,314,886
Ensembl chrNW_004955449:5,160,946...5,314,948
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chrNW_004955442:15,132,555...15,178,377
Ensembl chrNW_004955442:15,145,640...15,178,377
JBrowse link
G Slc15a1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955404:11,799,370...11,856,854
Ensembl chrNW_004955404:11,798,927...11,857,982
JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955427:21,221,778...21,255,725
Ensembl chrNW_004955427:21,221,750...21,255,725
JBrowse link
G Slc22a6 solute carrier family 22 member 6 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955599:302,026...307,503
Ensembl chrNW_004955599:301,981...311,447
JBrowse link
G Slc2a5 solute carrier family 2 member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955486:4,194,568...4,208,568
Ensembl chrNW_004955486:4,194,833...4,211,377
JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chrNW_004955447:1,599,986...1,900,791
Ensembl chrNW_004955447:1,599,929...1,900,791
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Umod uromodulin involved_in ISO (PMID:18618131) UniProt PMID:18618131 NCBI chrNW_004955442:3,986,936...4,001,155
Ensembl chrNW_004955442:3,985,308...3,999,598
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796
JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:18431508) UniProt PMID:18431508 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat4 FAT atypical cadherin 4 acts_upstream_of_or_within ISO (PMID:23974041) MGI PMID:23974041 NCBI chrNW_004955428:15,621,333...15,812,167
Ensembl chrNW_004955428:15,622,498...15,810,896
JBrowse link
G Lif LIF interleukin 6 family cytokine involved_in ISO (PMID:20624457) BHF-UCL PMID:20624457 NCBI chrNW_004955455:4,489,515...4,505,439
Ensembl chrNW_004955455:4,489,421...4,497,940
JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:17314325) UniProt PMID:17314325 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 acts_upstream_of_or_within ISO (PMID:23974041) MGI PMID:23974041 NCBI chrNW_004955448:745,419...868,313
Ensembl chrNW_004955448:745,419...868,602
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO (PMID:23974041) MGI PMID:23974041 NCBI chrNW_004955412:5,423,866...5,533,728
Ensembl chrNW_004955412:5,423,855...5,534,408
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    developmental process 5955
      anatomical structure development 5632
        nephron development 173
          nephron epithelium development 130
            metanephric nephron epithelium development 30
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 0
              metanephric nephron tubule development + 26
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 12561
    developmental process 5955
      anatomical structure development 5632
        multicellular organism development 4608
          system development 4011
            renal system development 381
              kidney development 367
                kidney epithelium development 163
                  nephron epithelium development 130
                    metanephric nephron epithelium development 30
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 0
                      metanephric nephron tubule development + 26
                      metanephric short descending thin limb development 0
paths to the root