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ONTOLOGY REPORT - ANNOTATIONS

Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr16:604,366...605,560 JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775 		JBrowse link
G POU3F3 POU class 3 homeobox 3 involved_in ISO (MGI:2669573|PMID:12925600) UniProt PMID:12925600 MGI:2669573 NCBI chr2A:96,967,943...96,972,378 JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121 		JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814 		JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISO (MGI:2669573|PMID:12925600) UniProt PMID:12925600 MGI:2669573 NCBI chr2A:96,967,943...96,972,378 JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in ISO (MGI:3806730|PMID:18618131) UniProt PMID:18618131 MGI:3806730 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121 		JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775 		JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr16:604,366...605,560 JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (MGI:1289803|PMID:9693135) UniProt PMID:9693135 MGI:1289803 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISO (MGI:2669573|PMID:12925600) UniProt PMID:12925600 MGI:2669573 NCBI chr2A:96,967,943...96,972,378 JBrowse link
G WNT7B Wnt family member 7B acts_upstream_of_or_within ISO (PMID:19060336) MGI PMID:19060336 Ensembl chr22:44,988,647...45,044,841 JBrowse link
metanephric macula densa development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISO (MGI:2669573|PMID:12925600) UniProt PMID:12925600 MGI:2669573 NCBI chr2A:96,967,943...96,972,378 JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:19,333,101...19,340,267
Ensembl chr2A:19,451,067...19,458,229 		JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
G SOX8 SRY-box transcription factor 8 acts_upstream_of_or_within ISO (PMID:21212101) MGI PMID:21212101
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:21212101) MGI PMID:21212101 NCBI chr17:66,028,737...66,034,122 JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in ISO (MGI:3056024|PMID:15465493) UniProt PMID:15465493 MGI:3056024 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:27,330,279...27,437,201
Ensembl chr11:27,229,963...27,291,571 		JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16886065) Ensembl
MGI		 PMID:16886065 GO_REF:0000107 NCBI chr 3:49,045,419...49,057,340
Ensembl chr 3:50,125,460...50,137,074 		JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:155,038,753...155,064,332 JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:7733320 RGD:2326090 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787 		JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in ISO (MGI:3806730|PMID:18618131) UniProt PMID:18618131 MGI:3806730 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in ISO (MGI:3806730|PMID:18618131) UniProt PMID:18618131 MGI:3806730 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:30645697 RGD:155631307 NCBI chr15:68,479,349...68,509,238
Ensembl chr15:87,681,826...87,703,713 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:30645697 RGD:155631307 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
G LRP2 LDL receptor related protein 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr2B:56,407,871...56,640,471
Ensembl chr2B:173,873,767...174,103,697 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) UniProt PMID:11891195 NCBI chr16:604,366...605,560 JBrowse link
G SLC15A1 solute carrier family 15 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr13:79,855,805...79,902,215
Ensembl chr13:98,998,894...99,065,008 		JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 3:118,996,023...119,044,423
Ensembl chr 3:125,902,978...125,951,963 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 6:158,004,545...158,046,428
Ensembl chr 6:163,014,663...163,054,681 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO RGD PMID:30645697 RGD:155631307 NCBI chr11:58,328,476...58,336,887
Ensembl chr11:61,680,016...61,688,223 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 1:7,792,361...7,840,634
Ensembl chr 1:9,028,790...9,078,509 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO RGD PMID:30645697 RGD:155631307 NCBI chr 4:52,659,221...52,994,053
Ensembl chr 4:59,002,200...59,385,608 		JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in ISO (MGI:2669573|PMID:12925600) UniProt PMID:12925600 MGI:2669573 NCBI chr2A:96,967,943...96,972,378 JBrowse link
G UMOD uromodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121 		JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAT4 FAT atypical cadherin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23974041) Ensembl
MGI		 PMID:23974041 GO_REF:0000107 NCBI chr 4:117,494,842...117,674,382
Ensembl chr 4:128,637,516...128,814,407 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:11,276,576...11,282,972
Ensembl chr22:29,078,862...29,095,608 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23974041) Ensembl
MGI		 PMID:23974041 GO_REF:0000107 NCBI chr 3:146,536,564...146,678,847
Ensembl chr 3:154,114,034...154,254,490 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23974041) Ensembl
MGI		 PMID:23974041 GO_REF:0000107 NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    developmental process 6551
      anatomical structure development 6160
        nephron development 185
          nephron epithelium development 139
            metanephric nephron epithelium development 32
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 1
              metanephric nephron tubule development + 28
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 16313
    developmental process 6551
      anatomical structure development 6160
        multicellular organism development 4965
          system development 4315
            renal system development 404
              kidney development 391
                kidney epithelium development 174
                  nephron epithelium development 139
                    metanephric nephron epithelium development 32
                      metanephric early distal convoluted tubule development 0
                      metanephric glomerular epithelium development + 4
                      metanephric late distal convoluted tubule development 0
                      metanephric long descending thin limb development + 0
                      metanephric macula densa development 1
                      metanephric nephron tubule development + 28
                      metanephric short descending thin limb development 0
paths to the root