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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron epithelium development
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Accession:GO:0072243 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


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metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2138070 (MGI:3664526|PMID:16886065)
Ensembl
RGD
PMID:16886065 GO_REF:0000107 MGI:3664526 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin involved_in ISO (PMID:11786407) RGD PMID:11786407 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:2669573|PMID:12925600)
UniProt
RGD
PMID:12925600 GO_REF:0000024 MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO MGI:3793280 (MGI:3821953|PMID:19060336) RGD PMID:19060336 MGI:3821953 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
metanephric macula densa development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2669573|PMID:12925600)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3826342|PMID:18835385)
UniProt
RGD
PMID:18835385 GO_REF:0000024 MGI:3826342 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:98371 (MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:14,932,348...14,937,336
Ensembl chr10:14,932,348...14,937,336
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:98370 (MGI:4939090|PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15465493)
Ensembl
RGD
PMID:15465493 GO_REF:0000107 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 acts_upstream_of_or_within ISO (PMID:15465493) RGD PMID:15465493 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISO (MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:5006869 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 IEP RGD PMID:7733320 RGD:2326090 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(MGI:3795840|PMID:18431508)
UniProt
RGD
PMID:18431508 GO_REF:0000024 MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat4 FAT atypical cadherin 4 acts_upstream_of_or_within ISO (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
Ensembl chr 2:125,752,130...125,879,387
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in IEA
ISO
GO_REF:0000107
(PMID:20624457)
Ensembl
RGD
PMID:20624457 GO_REF:0000107 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 acts_upstream_of_or_within ISO MGI:103262 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:1917649 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        nephron development 166
          nephron epithelium development 124
            metanephric nephron epithelium development 24
              metanephric early distal convoluted tubule development 0
              metanephric glomerular epithelium development + 4
              metanephric late distal convoluted tubule development 0
              metanephric long descending thin limb development + 0
              metanephric macula densa development 1
              metanephric nephron tubule development + 20
              metanephric short descending thin limb development 0
Path 2
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        multicellular organism development 5617
          system development 5288
            urogenital system development 435
              renal system development 387
                kidney development 373
                  kidney epithelium development 160
                    metanephric epithelium development 29
                      metanephric nephron epithelium development 24
                        metanephric early distal convoluted tubule development 0
                        metanephric glomerular epithelium development + 4
                        metanephric late distal convoluted tubule development 0
                        metanephric long descending thin limb development + 0
                        metanephric macula densa development 1
                        metanephric nephron tubule development + 20
                        metanephric short descending thin limb development 0
paths to the root