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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron tubule development
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Accession:GO:0072234 term browser browse the term
Definition:The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.



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metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18835385)
UniProt
RGD
PMID:18835385 GO_REF:0000024 NCBI chr 6:32,369,561...32,380,822 JBrowse link
metanephric ascending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,573,779...13,621,138 JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:5,237,135...5,280,455 JBrowse link
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998 JBrowse link
G Umod uromodulin involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 1:173,816,341...173,829,681 JBrowse link
metanephric connecting tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,375,624...29,402,532 JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:12925600)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998 JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,812,784...85,824,964 JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,375,624...29,402,532 JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454 JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363 JBrowse link
G Umod uromodulin involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 1:173,816,341...173,829,681 JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:5,237,135...5,280,455 JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,573,779...13,621,138 JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:12925600)
UniProt
RGD
PMID:12925600 GO_REF:0000024 NCBI chr 9:44,945,872...44,948,998 JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO MGI:3793280 (PMID:19060336) RGD PMID:19060336 NCBI chr 7:116,634,817...116,679,459 JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454 JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363 JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:98371 (PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 NCBI chr10:15,089,357...15,094,345 JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:98370 (PMID:21212101)
UniProt
RGD
PMID:21212101 GO_REF:0000024 NCBI chr10:98,305,744...98,311,250 JBrowse link
metanephric nephron tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:15465493)
Ensembl
RGD
PMID:15465493 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045 JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (PMID:15465493) RGD PMID:15465493 NCBI chr 5:165,522,138...165,523,684 JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISO (PMID:21523854) RGD PMID:21523854 NCBI chr 3:96,447,385...96,550,006 JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 IEP RGD PMID:7733320 RGD:2326090 NCBI chr 8:53,979,813...54,008,861 JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,812,784...85,824,964 JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,812,784...85,824,964 JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:133,767,332...133,810,137 JBrowse link
G Aqp1 aquaporin 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 4:85,812,784...85,824,964 JBrowse link
G Lrp2 LDL receptor related protein 2 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 3:54,189,305...54,346,769 JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,573,779...13,621,138 JBrowse link
G Slc15a1 solute carrier family 15 member 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr15:98,537,641...98,582,544 JBrowse link
G Slc15a2 solute carrier family 15 member 2 IEP RGD PMID:30645697 RGD:155631307 NCBI chr11:64,014,182...64,043,228 JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:48,076,657...48,103,679 JBrowse link
G Slc22a6 solute carrier family 22 member 6 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:214,951,493...214,960,317 JBrowse link
G Slc2a5 solute carrier family 2 member 5 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 5:160,583,055...160,609,994 JBrowse link
G Slc4a4 solute carrier family 4 member 4 IEP RGD PMID:30645697 RGD:155631307 NCBI chr14:18,841,289...19,293,297 JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:12925600)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998 JBrowse link
G Umod uromodulin involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 1:173,816,341...173,829,681 JBrowse link
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454 JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363 JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454 JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363 JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat4 FAT atypical cadherin 4 acts_upstream_of_or_within ISO (PMID:23974041) RGD PMID:23974041 NCBI chr 2:121,927,266...122,056,700 JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:79,131,049...79,140,486 JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454 JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363 JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 acts_upstream_of_or_within ISO MGI:103262 (PMID:23974041) RGD PMID:23974041 NCBI chr 2:141,651,159...141,766,919 JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1917649 (PMID:23974041)
Ensembl
RGD
PMID:23974041 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    multicellular organismal process 8969
      multicellular organism development 5330
        tube development 1346
          metanephric tubule development 32
            metanephric nephron tubule development 28
              apoptotic process involved in metanephric nephron tubule development + 2
              metanephric ascending thin limb development 4
              metanephric connecting tubule development + 1
              metanephric distal convoluted tubule development + 5
              metanephric distal tubule development + 7
              metanephric loop of Henle development + 6
              metanephric nephron tubule epithelial cell differentiation + 6
              metanephric nephron tubule morphogenesis + 8
              metanephric proximal convoluted tubule development + 2
              metanephric proximal straight tubule development 1
              metanephric proximal tubule development + 11
              metanephric thick ascending limb development 2
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            renal system development 423
              kidney development 409
                kidney epithelium development 179
                  metanephric epithelium development 37
                    metanephric nephron epithelium development 32
                      metanephric nephron tubule development 28
                        apoptotic process involved in metanephric nephron tubule development + 2
                        metanephric ascending thin limb development 4
                        metanephric connecting tubule development + 1
                        metanephric distal convoluted tubule development + 5
                        metanephric distal tubule development + 7
                        metanephric loop of Henle development + 6
                        metanephric nephron tubule epithelial cell differentiation + 6
                        metanephric nephron tubule morphogenesis + 8
                        metanephric proximal convoluted tubule development + 2
                        metanephric proximal straight tubule development 1
                        metanephric proximal tubule development + 11
                        metanephric thick ascending limb development 2
paths to the root