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ONTOLOGY REPORT - ANNOTATIONS

Term:metanephric glomerulus development
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Accession:GO:0072224 term browser browse the term
Definition:The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
Synonyms:exact_synonym: metanephric glomerular development


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metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LHX1 LIM homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:36,936,785...36,944,612
Ensembl chr17:36,936,785...36,944,612 		JBrowse link
metanephric glomerular basement membrane development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16886065), (PMID:7670489) Ensembl
MGI		 PMID:7670489 PMID:16886065 GO_REF:0000107 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
metanephric glomerular capillary formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G TCF21 transcription factor 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:133,889,113...133,895,537
Ensembl chr 6:133,889,113...133,895,553 		JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (MGI:1289803|PMID:9693135) UniProt PMID:9693135 MGI:1289803 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISS UniProt GO_REF:0000024 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD34 CD34 molecule involved_in IEP (PMID:1868864) UniProt PMID:1868864 NCBI chr 1:207,880,972...207,911,125
Ensembl chr 1:207,880,972...207,911,402 		JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISO (MGI:1289803|PMID:9693135) UniProt PMID:9693135 MGI:1289803 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
metanephric glomerular mesangium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRB platelet derived growth factor receptor beta involved_in ISO (MGI:1289803|PMID:9693135) UniProt PMID:9693135 MGI:1289803 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
metanephric glomerulus morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRB platelet derived growth factor receptor beta involved_in ISO PMID:10734101 UniProt PMID:10734101 RGD:8554631 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
metanephric glomerulus vasculature development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:19,344,874...19,358,623
Ensembl chr 2:19,351,485...19,358,623 		JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16886065) Ensembl
MGI		 PMID:16886065 GO_REF:0000107 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEP (PMID:11786407) UniProt PMID:11786407 NCBI chr 1:179,550,539...179,575,948
Ensembl chr 1:179,550,539...179,575,952 		JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WT1 WT1 transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR1 early growth response 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944 		JBrowse link
G RET ret proto-oncogene involved_in IEA
ISS		 (PMID:17047028) Ensembl
UniProt		 PMID:17047028 GO_REF:0000107 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure development 7020
        glomerulus development 82
          metanephric glomerulus development 17
            metanephric glomerular basement membrane development 1
            metanephric glomerular epithelium development + 4
            metanephric glomerulus morphogenesis + 3
            metanephric glomerulus vasculature development + 9
            negative regulation of metanephric glomerulus development 0
            positive regulation of metanephric glomerulus development 3
            regulation of metanephric glomerulus development + 3
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure development 7020
        multicellular organism development 5632
          system development 4908
            renal system development 413
              kidney development 401
                metanephros development 109
                  metanephric nephron development 43
                    metanephric glomerulus development 17
                      metanephric glomerular basement membrane development 1
                      metanephric glomerular epithelium development + 4
                      metanephric glomerulus morphogenesis + 3
                      metanephric glomerulus vasculature development + 9
                      negative regulation of metanephric glomerulus development 0
                      positive regulation of metanephric glomerulus development 3
                      regulation of metanephric glomerulus development + 3
paths to the root