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ONTOLOGY REPORT - ANNOTATIONS

Term:metanephric glomerulus development
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Accession:GO:0072224 term browser browse the term
Definition:The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
Synonyms:exact_synonym: metanephric glomerular development


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metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISO (MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:5006869 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in IEP PMID:9496787 UniProt PMID:9496787 RGD:8553921 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
metanephric glomerular basement membrane development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2138070 (MGI:3664526|PMID:16886065), (MGI:75217|PMID:7670489)		 Ensembl
RGD		 PMID:7670489 PMID:16886065 GO_REF:0000107 MGI:3664526 MGI:75217 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
metanephric glomerular capillary formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:P05622 (MGI:1931346|PMID:11239463)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:11239463 GO_REF:0000024 GO_REF:0000107 MGI:1931346 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:P26618 (MGI:1931346|PMID:11239463)		 UniProt
RGD		 PMID:11239463 GO_REF:0000024 MGI:1931346 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Tcf21 transcription factor 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2651771|PMID:12619136)		 UniProt
RGD		 PMID:12619136 GO_REF:0000024 MGI:2651771 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISS
ISO		 GO_REF:0000024
(MGI:3039044|PMID:15084468)		 UniProt
RGD		 PMID:15084468 GO_REF:0000024 MGI:3039044 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO (PMID:1868864) RGD PMID:1868864 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (MGI:1289803|PMID:9693135) RGD PMID:9693135 MGI:1289803 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:1289803|PMID:9693135)		 UniProt
RGD		 PMID:9693135 GO_REF:0000024 MGI:1289803 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
metanephric glomerular mesangium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta acts_upstream_of_or_within ISO (PMID:9693135) RGD PMID:9693135 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2138070 (MGI:3664526|PMID:16886065)		 Ensembl
RGD		 PMID:16886065 GO_REF:0000107 MGI:3664526 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin involved_in ISO (PMID:11786407) RGD PMID:11786407 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313 		JBrowse link
metanephric glomerulus morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta involved_in IEP PMID:10734101 UniProt PMID:10734101 RGD:8554631 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
metanephric glomerulus vasculature development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3826342|PMID:18835385)		 UniProt
RGD		 PMID:18835385 GO_REF:0000024 MGI:3826342 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:1332959|PMID:10077614)		 UniProt
RGD		 PMID:10077614 GO_REF:0000024 MGI:1332959 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(MGI:3795840|PMID:18431508)		 UniProt
RGD		 PMID:18431508 GO_REF:0000024 MGI:3795840 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (MGI:3808848|PMID:18607644) RGD PMID:18607644 MGI:3808848 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3697544|PMID:17047028)		 UniProt
RGD		 PMID:17047028 GO_REF:0000024 MGI:3697544 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (MGI:3697544|PMID:17047028) RGD PMID:17047028 MGI:3697544 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        glomerulus development 75
          metanephric glomerulus development 17
            metanephric glomerular basement membrane development 1
            metanephric glomerular epithelium development + 4
            metanephric glomerulus morphogenesis + 3
            metanephric glomerulus vasculature development + 9
            negative regulation of metanephric glomerulus development 0
            positive regulation of metanephric glomerulus development 3
            regulation of metanephric glomerulus development + 3
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            urogenital system development 439
              renal system development 391
                kidney development 377
                  nephron development 168
                    metanephric nephron development 42
                      metanephric glomerulus development 17
                        metanephric glomerular basement membrane development 1
                        metanephric glomerular epithelium development + 4
                        metanephric glomerulus morphogenesis + 3
                        metanephric glomerulus vasculature development + 9
                        negative regulation of metanephric glomerulus development 0
                        positive regulation of metanephric glomerulus development 3
                        regulation of metanephric glomerulus development + 3
paths to the root