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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric distal convoluted tubule development
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Accession:GO:0072221 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.



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metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:44,945,872...44,948,986
Ensembl chr 9:44,945,872...44,948,992
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        tube development 1245
          metanephric tubule development 24
            metanephric nephron tubule development 20
              metanephric distal convoluted tubule development 5
                metanephric DCT cell differentiation + 3
                metanephric early distal convoluted tubule development 0
                metanephric late distal convoluted tubule development 0
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        multicellular organism development 5800
          system development 5439
            urogenital system development 445
              renal system development 397
                kidney development 383
                  nephron development 172
                    nephron epithelium development 129
                      nephron tubule development 108
                        distal tubule development 12
                          distal convoluted tubule development 5
                            metanephric distal convoluted tubule development 5
                              metanephric DCT cell differentiation + 3
                              metanephric early distal convoluted tubule development 0
                              metanephric late distal convoluted tubule development 0
paths to the root