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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric distal convoluted tubule development
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Accession:GO:0072221 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.



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metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO
IEA
(PMID:18618131)
GO_REF:0000107
RGD
Ensembl
PMID:18618131 GO_REF:0000107 NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:253,555,447...253,646,623
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17314325)
UniProt
Ensembl
RGD
PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Umod uromodulin involved_in ISO
IEA
(PMID:18618131)
GO_REF:0000107
RGD
Ensembl
PMID:18618131 GO_REF:0000107 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:12925600)
Ensembl
UniProt
RGD
PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:52,438,026...52,441,152
Ensembl chr 9:44,945,872...44,948,992
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 NCBI chr 1:253,555,447...253,646,623
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17314325)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        tube development 1353
          metanephric tubule development 32
            metanephric nephron tubule development 28
              metanephric distal convoluted tubule development 5
                metanephric DCT cell differentiation + 3
                metanephric early distal convoluted tubule development 0
                metanephric late distal convoluted tubule development 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        multicellular organism development 5353
          system development 4635
            renal system development 422
              kidney development 408
                nephron development 192
                  nephron epithelium development 142
                    nephron tubule development 120
                      distal tubule development 12
                        distal convoluted tubule development 5
                          metanephric distal convoluted tubule development 5
                            metanephric DCT cell differentiation + 3
                            metanephric early distal convoluted tubule development 0
                            metanephric late distal convoluted tubule development 0
paths to the root