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ONTOLOGY REPORT - ANNOTATIONS

Term:cell differentiation involved in metanephros development
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Accession:GO:0072202 term browser browse the term
Definition:The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.


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mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMO smoothened, frizzled class receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033 		JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:70,966,694...70,991,860
Ensembl chr 4:70,971,432...70,989,714 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:1335967|PMID:10322633) UniProt PMID:10322633 MGI:1335967 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PAX8 paired box 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:24550112) Ensembl
MGI		 PMID:24550112 GO_REF:0000107 NCBI chr 2:64,242,742...64,260,021
Ensembl chr 2:64,243,987...64,259,521 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,399,152...47,403,503
Ensembl chr10:47,400,034...47,403,509 		JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU3F3 POU class 3 homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,513,872...38,517,692
Ensembl chr10:38,513,013...38,514,684 		JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFB platelet derived growth factor subunit B involved_in ISS UniProt GO_REF:0000024 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD34 CD34 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,734,363...6,747,991
Ensembl chr 7:6,734,363...6,748,581 		JBrowse link
metanephric interstitial fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228 		JBrowse link
metanephric mesenchymal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3663200|PMID:16368682) UniProt PMID:16368682 MGI:3663200 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G TCF21 transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,856,281...26,859,654
Ensembl chr 1:26,856,587...26,859,647 		JBrowse link
metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMB2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16886065) Ensembl
MGI		 PMID:16886065 GO_REF:0000107 NCBI chr20:40,036,967...40,062,628
Ensembl chr20:40,050,157...40,062,523 		JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,347,526...20,375,975
Ensembl chr 7:20,354,134...20,374,020 		JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in ISO PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:56,327,104...56,332,608
Ensembl chr  X:56,327,182...56,332,047 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17537789) Ensembl
MGI		 PMID:17537789 GO_REF:0000107 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G SALL1 spalt like transcription factor 1 acts_upstream_of_or_within ISO (PMID:24550112) MGI PMID:24550112 NCBI chr 2:64,242,742...64,260,021
Ensembl chr 2:64,243,987...64,259,521 		JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:70,966,694...70,991,860
Ensembl chr 4:70,971,432...70,989,714 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:2445273|PMID:12435636) UniProt PMID:12435636 MGI:2445273 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178 		JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178 		JBrowse link
positive regulation of metanephric podocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844 		JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT9B Wnt family member 9B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16054034) Ensembl
MGI		 PMID:16054034 GO_REF:0000107 NCBI chr 9:10,157,607...10,172,664
Ensembl chr 9:10,149,842...10,172,654 		JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAT4 FAT atypical cadherin 4 acts_upstream_of_or_within ISO (PMID:23974041) MGI PMID:23974041 NCBI chr19:15,157,595...15,332,821
Ensembl chr19:15,158,922...15,332,045 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3704067|PMID:17314325) UniProt PMID:17314325 MGI:3704067 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23974041) Ensembl
MGI		 PMID:23974041 GO_REF:0000107 NCBI chr23:44,277,707...44,409,911
Ensembl chr23:44,278,557...44,410,007 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23974041) Ensembl
MGI		 PMID:23974041 GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      cellular developmental process 4594
        cell differentiation 4593
          cell differentiation involved in kidney development 61
            cell differentiation involved in metanephros development 22
              mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
              metanephric DCT cell differentiation + 3
              metanephric glomerular epithelial cell differentiation + 3
              metanephric interstitial fibroblast differentiation + 1
              metanephric juxtaglomerulus cell differentiation + 0
              metanephric mesangial cell differentiation + 2
              metanephric mesenchymal cell differentiation 3
              metanephric nephron tubule epithelial cell differentiation + 6
Path 2
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      anatomical structure development 6414
        multicellular organism development 5174
          system development 4502
            renal system development 414
              kidney development 401
                cell differentiation involved in kidney development 61
                  cell differentiation involved in metanephros development 22
                    mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis 0
                    mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
                    metanephric DCT cell differentiation + 3
                    metanephric glomerular epithelial cell differentiation + 3
                    metanephric interstitial fibroblast differentiation + 1
                    metanephric juxtaglomerulus cell differentiation + 0
                    metanephric mesangial cell differentiation + 2
                    metanephric mesenchymal cell differentiation 3
                    metanephric nephron tubule epithelial cell differentiation + 6
paths to the root