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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:cell proliferation involved in kidney development
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Accession:GO:0072111 term browser browse the term
Definition:The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.



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cell proliferation involved in kidney development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin acts_upstream_of ISO MGI:3774414|MGI:3774416|MGI:3829641|MGI:3842151 (MGI:3772618|PMID:18182616), (MGI:3829339|PMID:18974783), (MGI:4397718|PMID:19850877), (MGI:4461845|PMID:19843504) RGD PMID:18182616 PMID:18974783 PMID:19843504 PMID:19850877 MGI:3772618 MGI:3829339 MGI:4397718 MGI:4461845 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2159356 (MGI:1931343|PMID:11180950)
UniProt
RGD
PMID:11180950 GO_REF:0000024 MGI:1931343 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3697513|PMID:16790474)
UniProt
RGD
PMID:16790474 GO_REF:0000024 MGI:3697513 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817
JBrowse link
cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159356 (MGI:2156986|PMID:10402475)
Ensembl
RGD
PMID:10402475 GO_REF:0000107 MGI:2156986 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:4367286|PMID:19809516) RGD PMID:19809516 MGI:4367286 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IMP PMID:18723570 UniProt PMID:18723570 RGD:8553351 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
mesenchymal cell proliferation involved in ureteric bud development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:3583399|PMID:15925496)
Ensembl
RGD
PMID:15925496 GO_REF:0000107 MGI:3583399 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Gpc3 glypican 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3583399|PMID:15925496)
Ensembl
RGD
PMID:15925496 GO_REF:0000107 MGI:3583399 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
metanephric cap mesenchymal cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3826342|PMID:18835385)
UniProt
RGD
PMID:18835385 GO_REF:0000024 MGI:3826342 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817
JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (MGI:1289803|PMID:9693135) RGD PMID:9693135 MGI:1289803 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO
GO_REF:0000024
(MGI:1289803|PMID:9693135)
UniProt
RGD
PMID:9693135 GO_REF:0000024 MGI:1289803 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
metanephric mesenchymal cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P97471 (MGI:3623046|PMID:15342483) RGD PMID:15342483 MGI:3623046 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:2388350|PMID:12399320)
Ensembl
UniProt
RGD
PMID:12399320 GO_REF:0000024 GO_REF:0000107 MGI:2388350 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
negative regulation of cell proliferation involved in kidney development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:3774414|MGI:3774416|MGI:3829641|MGI:3842151 (MGI:3772618|PMID:18182616), (MGI:3829339|PMID:18974783), (MGI:4397718|PMID:19850877), (MGI:4461845|PMID:19843504)
UniProt
RGD
PMID:18182616 PMID:18974783 PMID:19843504 PMID:19850877 GO_REF:0000024 MGI:3772618 MGI:3829339 MGI:4397718 MGI:4461845 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
negative regulation of cell proliferation involved in mesonephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (MGI:3611949|PMID:16319112) RGD PMID:16319112 MGI:3611949 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17244894)
UniProt
Ensembl
RGD
PMID:17244894 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) RGD PMID:17244894 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Ifng interferon gamma IMP RGD PMID:1906384 RGD:10755757 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Mir125a microRNA 125a involved_in ISO (PMID:26563755) RGD PMID:26563755 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:1332959|PMID:10077614)
UniProt
RGD
PMID:10077614 GO_REF:0000024 MGI:1332959 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
positive regulation of cell proliferation involved in kidney development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lin28a lin-28 homolog A involved_in ISO (MGI:5574232|PMID:24732380) RGD PMID:24732380 MGI:5574232 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:24691542 RGD:11341715 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA
(PMID:26563755)
GO_REF:0000107
RGD
Ensembl
PMID:26563755 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:20135641 RGD:4892623 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:11788434), (PMID:16014047)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:11788434 PMID:16014047 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfd platelet derived growth factor D IMP RGD PMID:12937299 RGD:9854637 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:23,369,830...23,442,205
Ensembl chr13:23,395,671...23,442,205
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
positive regulation of metanephric cap mesenchymal cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:3830398|PMID:19161241)
UniProt
RGD
PMID:19161241 GO_REF:0000024 MGI:3830398 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A NOT|involved_in ISS
ISO
GO_REF:0000024
(PMID:11788434)
UniProt
RGD
PMID:11788434 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cell population proliferation 2280
        cell proliferation involved in kidney development 24
          cell proliferation involved in mesonephros development + 3
          cell proliferation involved in metanephros development + 10
          cell proliferation involved in pronephros development 0
          extraglomerular mesangial cell proliferation + 0
          glomerular mesangial cell proliferation + 15
          kidney mesenchymal cell proliferation + 2
          negative regulation of cell proliferation involved in kidney development + 7
          positive regulation of cell proliferation involved in kidney development + 10
          regulation of cell proliferation involved in kidney development + 18
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            renal system development 420
              kidney development 406
                cell proliferation involved in kidney development 24
                  cell proliferation involved in mesonephros development + 3
                  cell proliferation involved in metanephros development + 10
                  cell proliferation involved in pronephros development 0
                  extraglomerular mesangial cell proliferation + 0
                  glomerular mesangial cell proliferation + 15
                  kidney mesenchymal cell proliferation + 2
                  negative regulation of cell proliferation involved in kidney development + 7
                  positive regulation of cell proliferation involved in kidney development + 10
                  regulation of cell proliferation involved in kidney development + 18
paths to the root