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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerular mesangium development
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Accession:GO:0072109 term browser browse the term
Definition:The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.



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glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin, alpha 1, skeletal muscle involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:68,781,168...68,784,194
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acta2 actin alpha 2, smooth muscle involved_in ISO
IEA
(PMID:17464107)
GO_REF:0000107
RGD
Ensembl
PMID:17464107 GO_REF:0000107 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:100,811,987...100,817,523
JBrowse link
G Actg2 actin gamma 2, smooth muscle involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857740 (PMID:16498405) RGD PMID:16498405 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Gpr4 G protein-coupled receptor 4 acts_upstream_of_or_within ISO MGI:3700206 (PMID:17145776) RGD PMID:17145776 NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA
(PMID:15821257)
GO_REF:0000107
RGD
Ensembl
PMID:15821257 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IMP PMID:18723570 UniProt PMID:18723570 RGD:8553351 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISS
ISO
GO_REF:0000024
(PMID:15084468)
UniProt
RGD
PMID:15084468 GO_REF:0000024 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO (PMID:1868864) RGD PMID:1868864 NCBI chr13:109,008,786...109,029,317
Ensembl chr13:106,480,043...106,499,832
JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO
GO_REF:0000024
(PMID:9693135)
UniProt
RGD
PMID:9693135 GO_REF:0000024 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843
JBrowse link
metanephric glomerular mesangium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:9693135) RGD PMID:9693135 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843
JBrowse link
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17244894)
UniProt
Ensembl
RGD
PMID:17244894 GO_REF:0000024 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO
IEA
(PMID:17244894)
GO_REF:0000107
RGD
Ensembl
PMID:17244894 GO_REF:0000107 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Ifng interferon gamma IMP RGD PMID:1906384 RGD:10755757 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Mir125a microRNA 125a involved_in ISO (PMID:26563755) RGD PMID:26563755 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor involved_in ISS
ISO
GO_REF:0000024
(PMID:10077614)
UniProt
RGD
PMID:10077614 GO_REF:0000024 NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:24691542 RGD:11341715 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (PMID:26563755) RGD PMID:26563755 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:20135641 RGD:4892623 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:11788434), (PMID:16014047)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:11788434 PMID:16014047 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfd platelet derived growth factor D IMP RGD PMID:12937299 RGD:9854637 NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:23,369,830...23,442,205
Ensembl chr13:23,395,671...23,442,205
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A NOT|involved_in ISS
ISO
GO_REF:0000024
(PMID:11788434)
UniProt
RGD
PMID:11788434 GO_REF:0000024 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        blood vessel development 863
          glomerulus vasculature development 36
            glomerular mesangium development 23
              glomerular mesangial cell differentiation + 9
              glomerular mesangial cell proliferation + 15
              mesonephric glomerular mesangium development + 0
              metanephric glomerular mesangium development + 5
Path 2
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            circulatory system development 1387
              vasculature development 905
                renal system vasculature development 38
                  kidney vasculature development 38
                    glomerulus vasculature development 36
                      glomerular mesangium development 23
                        glomerular mesangial cell differentiation + 9
                        glomerular mesangial cell proliferation + 15
                        mesonephric glomerular mesangium development + 0
                        metanephric glomerular mesangium development + 5
paths to the root