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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of stem cell proliferation
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Accession:GO:0072091 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.


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regulation of stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07015743.1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024
G Ago3 argonaute RISC catalytic component 3 involved_in ISO (PMID:23064648) RGD PMID:23064648 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit acts_upstream_of_or_within ISO MGI:3819698 (MGI:5013871|PMID:21609717) RGD PMID:21609717 MGI:5013871 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IMP RGD PMID:18690792 RGD:2325179 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5568800|PMID:24391977)
AgBase
RGD
PMID:24391977 GO_REF:0000024 MGI:5568800 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgb2l1 high mobility group box 2-like 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr11:47,252,583...47,253,646
Ensembl chr11:47,252,569...47,253,669
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor acts_upstream_of_or_within ISO MGI:2686901 (MGI:5502303|PMID:20711984) RGD PMID:20711984 MGI:5502303 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (MGI:5467164|PMID:22977234) RGD PMID:22977234 MGI:5467164 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Nf2 neurofibromin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103262|MGI:1926955 (MGI:5618041|PMID:25433207)
Ensembl
RGD
PMID:25433207 GO_REF:0000107 MGI:5618041 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G RGD1559962 similar to High mobility group protein 2 (HMG-2) involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 1:19,409,285...19,410,183
Ensembl chr 1:19,409,539...19,410,168
JBrowse link
G RGD1561694 similar to High mobility group protein 2 (HMG-2) involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr14:69,045,590...69,046,623
Ensembl chr14:69,045,641...69,046,640
JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:97307 (MGI:4398748|PMID:19952108), (MGI:4398802|PMID:19853564), (MGI:5618041|PMID:25433207)
(PMID:25433207)
RGD PMID:19853564 PMID:19952108 PMID:25433207 MGI:4398748 MGI:4398802 MGI:5618041 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5784967|PMID:24733888)
UniProt
RGD
PMID:24733888 GO_REF:0000024 MGI:5784967 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
negative regulation of stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbln1 fibulin 1 involved_in ISO (PMID:11238726) RGD PMID:11238726 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fermt1 FERM domain containing kindlin 1 involved_in ISO (MGI:5571208|PMID:24681597) RGD PMID:24681597 MGI:5571208 NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555
JBrowse link
G Kdf1 keratinocyte differentiation factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5529391|PMID:24075906)
UniProt
RGD
PMID:24075906 GO_REF:0000024 MGI:5529391 NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:5581807|PMID:18243104) RGD PMID:18243104 MGI:5581807 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 acts_upstream_of_or_within ISO MGI:1338039 (MGI:5584327|PMID:24735878) RGD PMID:24735878 MGI:5584327 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831
JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO MGI:1330290 (MGI:5584327|PMID:24735878) RGD PMID:24735878 MGI:5584327 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO MGI:2447174 (MGI:4436954|PMID:20032500) RGD PMID:20032500 MGI:4436954 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
positive regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1l ataxin 1-like acts_upstream_of_or_within ISO MGI:5301616 (MGI:5477838|PMID:23555280) RGD PMID:23555280 MGI:5477838
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5586806|PMID:10725737)
Ensembl
RGD
PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6392952|PMID:31827282)
GO_REF:0000107
(PMID:31827282)
UniProt
RGD
Ensembl
PMID:31827282 GO_REF:0000024 GO_REF:0000107 MGI:6392952 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (MGI:5433809|PMID:21540074) RGD PMID:21540074 MGI:5433809 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 involved_in ISO (PMID:19506020) RGD PMID:19506020 NCBI chr12:137,342...200,294
Ensembl chr12:103,590...197,784
JBrowse link
G Pdcd2 programmed cell death 2 involved_in ISO (PMID:22922207) RGD PMID:22922207 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Thpo thrombopoietin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:21540074)
RGD PMID:21540074 PMID:21873635 RGD:13792537 Ensembl chr11:80,182,820...80,188,167 JBrowse link
positive regulation of mesenchymal stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IMP RGD PMID:19723531 RGD:9068401 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Ccne1 cyclin E1 involved_in ISO
IEA
(PMID:23083510)
GO_REF:0000107
RGD
Ensembl
PMID:23083510 GO_REF:0000107 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:29496737) RGD PMID:29496737 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 involved_in ISO (PMID:18672106) RGD PMID:18672106 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Vegfc vascular endothelial growth factor C involved_in ISO (MGI:6378108|PMID:26934950) RGD PMID:26934950 MGI:6378108 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
positive regulation of stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epcam epithelial cell adhesion molecule involved_in ISO (PMID:19785009) RGD PMID:19785009 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO (PMID:30599359) RGD PMID:30599359 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Hdac5 histone deacetylase 5 involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:17624332), (PMID:21484705)
MGI:2386412 (MGI:3829847|PMID:18957199)
GO_REF:0000024
RGD
UniProt
PMID:17624332 PMID:18957199 PMID:21484705 GO_REF:0000024 MGI:3829847 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (MGI:4831049|PMID:20833368) RGD PMID:20833368 MGI:4831049 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Mir205 microRNA 205 acts_upstream_of_or_within ISO (MGI:5514438|PMID:23974039) RGD PMID:23974039 MGI:5514438 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir320a microRNA 320a acts_upstream_of_or_within ISO (MGI:5447874|PMID:22925886) RGD PMID:22925886 MGI:5447874 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Nanog Nanog homeobox involved_in ISO (PMID:16501172) RGD PMID:16501172 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha acts_upstream_of_or_within ISO (MGI:5474438|PMID:22969033) RGD PMID:22969033 MGI:5474438 NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898
JBrowse link
G Ngf nerve growth factor IDA RGD PMID:18846328 RGD:2303808 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr20:46,050,134...46,070,569
Ensembl chr20:46,050,414...46,073,949
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO (PMID:21911094) RGD PMID:21911094 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Setd1a SET domain containing 1A, histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:5568941 (MGI:5563281|PMID:24550110) RGD PMID:24550110 MGI:5563281 NCBI chr 1:182,386,197...182,411,695
Ensembl chr 1:182,388,060...182,411,090
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:3663736|PMID:16439206) RGD PMID:16439206 MGI:3663736 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(PMID:20626275)
UniProt
RGD
PMID:20626275 GO_REF:0000024 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Taf4b TATA-box binding protein associated factor 4b involved_in ISO (MGI:5619438|PMID:23350932) RGD PMID:23350932 MGI:5619438 NCBI chr18:5,952,737...6,086,408
Ensembl chr18:5,952,769...6,068,307
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3769504 (MGI:3788969|PMID:18356246) RGD PMID:18356246 MGI:3788969 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (MGI:3588604|PMID:16037417), (MGI:3589051|PMID:16107853) RGD PMID:16037417 PMID:16107853 MGI:3588604 MGI:3589051 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in IEA
ISO
GO_REF:0000107
(MGI:5613472|PMID:20116413)
Ensembl
RGD
PMID:20116413 GO_REF:0000107 MGI:5613472 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5487705|PMID:23403623)
UniProt
RGD
PMID:23403623 GO_REF:0000024 MGI:5487705 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (MGI:5490148|PMID:23495171) RGD PMID:23495171 MGI:5490148 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell population proliferation 2153
        regulation of cell population proliferation 1803
          regulation of stem cell proliferation 56
            negative regulation of stem cell proliferation + 7
            positive regulation of stem cell proliferation + 31
            regulation of hematopoietic stem cell proliferation + 10
            regulation of mesenchymal stem cell proliferation + 5
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          regulation of cell population proliferation 1803
            regulation of stem cell proliferation 56
              negative regulation of stem cell proliferation + 7
              positive regulation of stem cell proliferation + 31
              regulation of hematopoietic stem cell proliferation + 10
              regulation of mesenchymal stem cell proliferation + 5
paths to the root