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ONTOLOGY REPORT - ANNOTATIONS

Term:renal vesicle development
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Accession:GO:0072087 term browser browse the term
Definition:The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.

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renal vesicle development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696 		JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:3611729|PMID:16396903)		 Ensembl
UniProt
RGD		 PMID:16396903 GO_REF:0000024 GO_REF:0000107 MGI:3611729 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770 		JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:10706139)		 Ensembl
UniProt
RGD		 PMID:10706139 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IDA
ISO
IEA		 PMID:17522159
(PMID:10322633)
GO_REF:0000107		 RGD
Ensembl		 PMID:10322633, PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (MGI:3714585|PMID:17522159) RGD PMID:17522159 MGI:3714585 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989 		JBrowse link
G Pax2 paired box 2 ISO
ISS		 (PMID:10322633)
GO_REF:0000024		 RGD
UniProt		 PMID:10322633 GO_REF:0000024 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329 		JBrowse link
G Pax8 paired box 8 ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946 		JBrowse link
G Sall1 spalt-like transcription factor 1 ISO (PMID:11511981)
(MGI:2149437|PMID:11688560)		 RGD PMID:11511981 PMID:11688560 MGI:2149437 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039 		JBrowse link
G Six2 SIX homeobox 2 ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276 		JBrowse link
metanephric renal vesicle morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx1 LIM homeobox 1 ISO (PMID:7909549) RGD PMID:7909549 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293 		JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692 		JBrowse link
G Ctnnb1 catenin beta 1 IEA
ISO		 GO_REF:0000107
(MGI:3714576|PMID:17537789)		 Ensembl
RGD		 PMID:17537789 GO_REF:0000107 MGI:3714576 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Sall1 spalt-like transcription factor 1 ISO MGI:3603818 (MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:5563280 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039 		JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor IEA
ISO		 GO_REF:0000107
(MGI:81286|PMID:8657306)		 Ensembl
RGD		 PMID:8657306 GO_REF:0000107 MGI:81286 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238 		JBrowse link
G Lif LIF, interleukin 6 family cytokine ISO
IEA		 (PMID:20624457)
GO_REF:0000107		 RGD
Ensembl		 PMID:20624457 GO_REF:0000107 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642 		JBrowse link
G Pax2 paired box 2 ISS
ISO		 GO_REF:0000024
UniProtKB:Q00288 (MGI:2445273|PMID:12435636)		 UniProt
RGD		 PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329 		JBrowse link
G Pax8 paired box 8 ISS
ISO		 GO_REF:0000024
(MGI:2445273|PMID:12435636)		 UniProt
RGD		 PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946 		JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B ISO MGI:3526437 (MGI:3588895|PMID:16054034) RGD PMID:16054034 MGI:3588895 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937 		JBrowse link
renal vesicle formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 IEA
ISO		 GO_REF:0000107
MGI:1858008 (MGI:3714576|PMID:17537789)		 Ensembl
RGD		 PMID:17537789 GO_REF:0000107 MGI:3714576 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Wnt4 Wnt family member 4 IEA
ISO		 GO_REF:0000107
(MGI:3588895|PMID:16054034)		 Ensembl
RGD		 PMID:16054034 GO_REF:0000107 MGI:3588895 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579 		JBrowse link
renal vesicle induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox8 SRY-box transcription factor 8 ISS
ISO		 GO_REF:0000024
(MGI:4939090|PMID:21212101)		 UniProt
RGD		 PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:14,932,348...14,937,336
Ensembl chr10:14,932,348...14,937,336 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISS
ISO		 GO_REF:0000024
(MGI:4939090|PMID:21212101)		 UniProt
RGD		 PMID:21212101 GO_REF:0000024 MGI:4939090 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Wnt4 Wnt family member 4 IEA
ISO		 GO_REF:0000107
(MGI:2150217|PMID:11507767)		 Ensembl
RGD		 PMID:11507767 GO_REF:0000107 MGI:2150217 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579 		JBrowse link
renal vesicle morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx1 LIM homeobox 1 ISS
ISO		 GO_REF:0000024
(MGI:5009392|PMID:17610272)		 UniProt
RGD		 PMID:17610272 GO_REF:0000024 MGI:5009392 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293 		JBrowse link
renal vesicle progenitor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 ISS
ISO		 GO_REF:0000024
(MGI:3826342|PMID:18835385)		 UniProt
RGD		 PMID:18835385 GO_REF:0000024 MGI:3826342 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667 		JBrowse link
ureteric bud invasion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmn1 formin 1 ISO (MGI:65439|PMID:7517224) RGD PMID:7517224 MGI:65439 NCBI chr 3:104,783,093...105,170,761
Ensembl chr 3:104,816,987...105,086,436 		JBrowse link
G Kif26b kinesin family member 26B ISO MGI:4459557 (MGI:4454194|PMID:20439720) RGD PMID:20439720 MGI:4454194 NCBI chr13:96,775,356...97,173,469
Ensembl chr13:96,775,357...97,173,469 		JBrowse link
G Sall1 spalt-like transcription factor 1 ISO MGI:2388379 (MGI:2149437|PMID:11688560), (MGI:3665498|PMID:16839447) RGD PMID:11688560 PMID:16839447 MGI:2149437 MGI:3665498 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        nephron development 166
          nephron epithelium development 124
            renal vesicle development 20
              renal vesicle morphogenesis + 18
              renal vesicle progenitor cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        multicellular organism development 5766
          system development 5298
            urogenital system development 434
              renal system development 384
                kidney development 370
                  kidney epithelium development 160
                    nephron epithelium development 124
                      renal vesicle development 20
                        renal vesicle morphogenesis + 18
                        renal vesicle progenitor cell differentiation 1
paths to the root