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ONTOLOGY REPORT - ANNOTATIONS

Term:metanephric mesenchyme development
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Accession:GO:0072075 term browser browse the term
Definition:The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.

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metanephric mesenchyme development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103216393 paired box protein Pax-2 involved_in ISO (PMID:20171952) UniProt PMID:20171952 NCBI chr 9:93,763,975...93,847,180 JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISO PMID:10734101 UniProt PMID:10734101 RGD:8554631 NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:36,369,226...36,445,713
Ensembl chr 7:36,369,524...36,443,612 		JBrowse link
G SIX1 SIX homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:37,840,399...37,855,801
Ensembl chr24:37,840,309...37,845,192 		JBrowse link
G SIX4 SIX homeobox 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:37,899,463...37,911,875
Ensembl chr24:37,900,909...37,911,612 		JBrowse link
G WT1 WT1 transcription factor involved_in ISO (PMID:8395349) UniProt PMID:8395349 NCBI chr 1:32,750,300...32,801,832 JBrowse link
metanephric cap mesenchymal cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263 		JBrowse link
metanephric mesenchymal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103216393 paired box protein Pax-2 involved_in ISO (PMID:16368682) UniProt PMID:16368682 NCBI chr 9:93,763,975...93,847,180 JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263 		JBrowse link
G TCF21 transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:39,607,179...39,610,336
Ensembl chr13:39,607,182...39,610,388 		JBrowse link
metanephric mesenchymal cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
metanephric mesenchyme morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944 		JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
positive regulation of metanephric cap mesenchymal cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19161241) UniProt PMID:19161241 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      anatomical structure development 6401
        animal organ development 3574
          kidney development 404
            metanephros development 111
              metanephric mesenchyme development 12
                metanephric cap development + 2
                metanephric mesenchymal cell differentiation 3
                metanephric mesenchymal cell proliferation involved in metanephros development 2
                metanephric mesenchyme morphogenesis + 4
Path 2
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      anatomical structure development 6401
        multicellular organism development 5150
          system development 4461
            renal system development 418
              kidney development 404
                metanephros development 111
                  metanephric mesenchyme development 12
                    metanephric cap development + 2
                    metanephric mesenchymal cell differentiation 3
                    metanephric mesenchymal cell proliferation involved in metanephros development 2
                    metanephric mesenchyme morphogenesis + 4
paths to the root