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ONTOLOGY REPORT - ANNOTATIONS

Term:distal convoluted tubule development
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Accession:GO:0072025 term browser browse the term
Definition:The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


show annotations for term's descendants           Sort by:
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:12925600) 		Ensembl
UniProt
RGD		 PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998
Ensembl chr 9:44,945,872...44,948,992 		JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO
IEA 		(PMID:18618131)
GO_REF:0000107 		RGD
Ensembl		 PMID:18618131 GO_REF:0000107 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17314325) 		UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax8 paired box 8 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17314325) 		UniProt
Ensembl
RGD		 PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Umod uromodulin involved_in ISO
IEA 		(PMID:18618131)
GO_REF:0000107 		RGD
Ensembl		 PMID:18618131 GO_REF:0000107 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17314325) 		UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:17314325)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    multicellular organismal process 9031
      multicellular organism development 5362
        tube development 1358
          renal tubule development 128
            nephron tubule development 121
              distal convoluted tubule development 5
                DCT cell differentiation + 3
                early distal convoluted tubule development + 0
                late distal convoluted tubule development + 0
                metanephric distal convoluted tubule development + 5
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            renal system development 423
              kidney development 409
                nephron development 193
                  nephron epithelium development 143
                    nephron tubule development 121
                      distal tubule development 12
                        distal convoluted tubule development 5
                          DCT cell differentiation + 3
                          early distal convoluted tubule development + 0
                          late distal convoluted tubule development + 0
                          metanephric distal convoluted tubule development + 5
paths to the root