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ONTOLOGY REPORT - ANNOTATIONS

Term:distal tubule development
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Accession:GO:0072017 term browser browse the term
Definition:The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.


show annotations for term's descendants           Sort by:
distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15821257) 		Ensembl
RGD		 PMID:15821257 GO_REF:0000107 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA 		(PMID:15821257)
GO_REF:0000107 		RGD
Ensembl		 PMID:15821257 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12695560) 		UniProt
Ensembl
RGD		 PMID:12695560 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:29,282,703...29,312,568
Ensembl chr 9:21,786,258...21,814,520 		JBrowse link
distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klhl3 kelch-like family member 3 involved_in ISO
IEA
ISS 		(PMID:22406640), (PMID:23453970), (PMID:23576762)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:22406640 PMID:23453970 PMID:23576762 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO
IEA
ISS 		(PMID:23453970), (PMID:23576762)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:23453970 PMID:23576762 GO_REF:0000024 GO_REF:0000107 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:12925600)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998
Ensembl chr 9:44,945,872...44,948,992 		JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 involved_in ISO
IEA 		(PMID:18618131)
GO_REF:0000107 		RGD
Ensembl		 PMID:18618131 GO_REF:0000107 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17314325) 		UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax8 paired box 8 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17314325) 		UniProt
Ensembl
RGD		 PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Umod uromodulin involved_in ISO
IEA 		(PMID:18618131)
GO_REF:0000107 		RGD
Ensembl		 PMID:18618131 GO_REF:0000107 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO
IEA 		(PMID:11891195)
GO_REF:0000107 		RGD
Ensembl		 PMID:11891195 GO_REF:0000107 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128 		JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:12925600)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:12925600 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:44,945,872...44,948,998
Ensembl chr 9:44,945,872...44,948,992 		JBrowse link
G Umod uromodulin involved_in ISO
IEA 		(PMID:18618131)
GO_REF:0000107 		RGD
Ensembl		 PMID:18618131 GO_REF:0000107 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17314325) 		UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:17314325)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:17314325 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        tube development 1358
          renal tubule development 128
            nephron tubule development 121
              distal tubule development 12
                distal convoluted tubule development + 5
                distal tubule morphogenesis + 3
                mesonephric distal tubule development + 0
                metanephric distal tubule development + 7
                pronephric distal tubule development + 0
                thick ascending limb development + 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            renal system development 423
              kidney development 409
                kidney epithelium development 178
                  nephron epithelium development 143
                    nephron tubule development 121
                      distal tubule development 12
                        distal convoluted tubule development + 5
                        distal tubule morphogenesis + 3
                        mesonephric distal tubule development + 0
                        metanephric distal tubule development + 7
                        pronephric distal tubule development + 0
                        thick ascending limb development + 2
paths to the root