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ONTOLOGY REPORT - ANNOTATIONS


Term:distal tubule development
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Accession:GO:0072017 term browser browse the term
Definition:The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.



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distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15821257)
Ensembl
RGD
PMID:15821257 GO_REF:0000107 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:2656435|PMID:12695560)
UniProt
RGD
PMID:12695560 GO_REF:0000024 MGI:2656435 NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520
JBrowse link
distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klhl3 kelch-like family member 3 involved_in ISO
ISS
(PMID:22406640), (PMID:23453970), (PMID:23576762)
GO_REF:0000024
RGD
UniProt
PMID:22406640 PMID:23453970 PMID:23576762 GO_REF:0000024 NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO
ISS
(PMID:23453970), (PMID:23576762)
GO_REF:0000024
RGD
UniProt
PMID:23453970 PMID:23576762 GO_REF:0000024 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:44,945,872...44,948,986
Ensembl chr 9:44,945,872...44,948,992
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024 GO_REF:0000107 MGI:2669573 NCBI chr 9:44,945,872...44,948,986
Ensembl chr 9:44,945,872...44,948,992
JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024 MGI:3704067 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        nephron development 171
          nephron epithelium development 129
            nephron tubule development 108
              distal tubule development 12
                distal convoluted tubule development + 5
                distal tubule morphogenesis + 3
                mesonephric distal tubule development + 0
                metanephric distal tubule development + 7
                pronephric distal tubule development + 0
                thick ascending limb development + 2
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            urogenital system development 443
              renal system development 395
                kidney development 381
                  nephron development 171
                    nephron epithelium development 129
                      nephron tubule development 108
                        distal tubule development 12
                          distal convoluted tubule development + 5
                          distal tubule morphogenesis + 3
                          mesonephric distal tubule development + 0
                          metanephric distal tubule development + 7
                          pronephric distal tubule development + 0
                          thick ascending limb development + 2
paths to the root