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ONTOLOGY REPORT - ANNOTATIONS

Term:proximal tubule development
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Accession:GO:0072014 term browser browse the term
Definition:The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.


show annotations for term's descendants           Sort by:
proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:27582095)
MGI:1889609 (PMID:18701606)		 UniProt
RGD		 PMID:18701606 PMID:27582095 GO_REF:0000024 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15821257)		 Ensembl
RGD		 PMID:15821257 GO_REF:0000107 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15821257)		 Ensembl
RGD		 PMID:15821257 GO_REF:0000107 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
metanephric proximal convoluted tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 IEP RGD PMID:7733320 RGD:2326090 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
metanephric proximal convoluted tubule segment 2 development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
metanephric proximal straight tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
metanephric proximal tubule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Aqp1 aquaporin 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Lrp2 LDL receptor related protein 2 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:14,077,733...14,125,682
Ensembl chr10:13,573,021...13,621,128 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 IEP RGD PMID:30645697 RGD:155631307 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 IEP RGD PMID:30645697 RGD:155631307 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 IEP RGD PMID:30645697 RGD:155631307 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
proximal tubule morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd5 COMM domain containing 5 involved_in IDA PMID:24515317 UniProt PMID:24515317 RGD:10047245 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      anatomical structure development 6638
        tube development 1355
          renal tubule development 127
            nephron tubule development 120
              proximal tubule development 17
                mesonephric proximal tubule development + 0
                metanephric proximal tubule development + 11
                pronephric proximal tubule development + 0
                proximal convoluted tubule development + 2
                proximal straight tubule development + 1
                proximal tubule morphogenesis + 2
Path 2
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      anatomical structure development 6638
        multicellular organism development 5350
          system development 4630
            renal system development 423
              kidney development 409
                kidney epithelium development 179
                  nephron epithelium development 143
                    nephron tubule development 120
                      proximal tubule development 17
                        mesonephric proximal tubule development + 0
                        metanephric proximal tubule development + 11
                        pronephric proximal tubule development + 0
                        proximal convoluted tubule development + 2
                        proximal straight tubule development + 1
                        proximal tubule morphogenesis + 2
paths to the root