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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of protein serine/threonine kinase activity
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Accession:GO:0071902 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.


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positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cab39 calcium binding protein 39 involved_in ISO (PMID:19892943), (PMID:24393035) ParkinsonsUK-UCL PMID:19892943 PMID:24393035 NCBI chrNW_004955453:4,582,530...4,670,978
Ensembl chrNW_004955453:4,582,530...4,671,157
JBrowse link
G Camk1 calcium/calmodulin dependent protein kinase I involved_in ISO (PMID:17442826) UniProt PMID:17442826 NCBI chrNW_004955561:1,282,970...1,292,710
Ensembl chrNW_004955561:1,282,970...1,294,972
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO (PMID:17975111) UniProt PMID:17975111 NCBI chrNW_004955416:15,102,632...15,106,372
Ensembl chrNW_004955416:15,102,632...15,106,372
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:19903888), (PMID:20080667)
(PMID:20080667)
BHF-UCL PMID:19903888 PMID:20080667 NCBI chrNW_004955419:6,229,437...6,416,619
Ensembl chrNW_004955419:6,228,591...6,416,402
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) UniProt PMID:27723717 PMID:27723720 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) UniProt PMID:20154697 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family member 1A acts_upstream_of_or_within ISO (PMID:25683712) MGI PMID:25683712 NCBI chrNW_004955420:28,040,320...28,050,723
Ensembl chrNW_004955420:28,045,410...28,049,758
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:19549901) UniProt PMID:19549901 NCBI chrNW_004955458:12,493,790...12,624,805 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO Akt1 RGD PMID:18443201 RGD:4108490 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:22504299) CAFA PMID:22504299 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:28389568) UniProt PMID:28389568 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO (PMID:8388392) UniProt PMID:8388392 NCBI chrNW_004955450:9,181,851...9,205,277
Ensembl chrNW_004955450:9,181,851...9,239,648
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 involved_in ISO (PMID:8388392) UniProt PMID:8388392 NCBI chrNW_004955495:4,695,239...4,718,380
Ensembl chrNW_004955495:4,695,768...4,722,098
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:20332113) UniProt PMID:20332113 NCBI chrNW_004955448:16,866,577...16,887,215
Ensembl chrNW_004955448:16,864,031...16,887,626
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:24036451) UniProt PMID:24036451 NCBI chrNW_004955559:1,390,823...1,395,550
Ensembl chrNW_004955559:1,391,314...1,396,329
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:16186805) UniProt PMID:16186805 NCBI chrNW_004955437:5,940,825...5,945,367
Ensembl chrNW_004955437:5,942,106...5,945,431
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:20080667) BHF-UCL PMID:20080667 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361
JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO (PMID:24056301) UniProt PMID:24056301 NCBI chrNW_004955459:9,533,081...9,574,464
Ensembl chrNW_004955459:9,531,538...9,574,766
JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:8617235) UniProt PMID:8617235 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451
JBrowse link
G Slc8a2 solute carrier family 8 member A2 acts_upstream_of_or_within ISO (PMID:29274751) ARUK-UCL PMID:29274751 NCBI chrNW_004955574:1,290,907...1,315,399
Ensembl chrNW_004955574:1,288,952...1,315,401
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19059439) UniProt PMID:19059439 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO (PMID:23300339) UniProt PMID:23300339 NCBI chrNW_004955519:1,556,376...1,575,144
Ensembl chrNW_004955519:1,553,463...1,575,198
JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO (PMID:18978355) MGI PMID:18978355 NCBI chrNW_004955414:28,166,562...28,341,275
Ensembl chrNW_004955414:28,175,543...28,333,856
JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chrNW_004955462:9,196,984...9,278,850
Ensembl chrNW_004955462:9,207,314...9,278,621
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:18431508)
(PMID:18431508), (PMID:19524870)
UniProt PMID:18431508 PMID:19524870 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:16272156) UniProt PMID:16272156 NCBI chrNW_004955471:12,670,837...12,838,910
Ensembl chrNW_004955471:12,670,764...12,815,430
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18687677) UniProt PMID:18687677 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link
G Spatc1l spermatogenesis and centriole associated 1 like acts_upstream_of_or_within ISO (PMID:30026308) MGI PMID:30026308 NCBI chrNW_004955407:42,621,167...42,629,350
Ensembl chrNW_004955407:42,620,679...42,629,350
JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccny cyclin Y involved_in ISO (PMID:19524571), (PMID:20059949) UniProt PMID:19524571 PMID:20059949 NCBI chrNW_004955462:5,937,292...6,088,310
Ensembl chrNW_004955462:5,937,292...6,088,310
JBrowse link
G Cdc6 cell division cycle 6 ISO RGD PMID:22223646 RGD:10045360 NCBI chrNW_004955451:14,857,174...14,871,324
Ensembl chrNW_004955451:14,860,309...14,871,494
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 ISO RGD PMID:10721722 RGD:632478 NCBI chrNW_004955422:27,878,048...27,907,157
Ensembl chrNW_004955422:27,879,389...27,906,861
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO RGD PMID:22223646 RGD:10045360 NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542
JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) AgBase PMID:24313324 NCBI chrNW_004955408:4,234,208...4,239,795 JBrowse link
G Mapre3 microtubule associated protein RP/EB family member 3 involved_in ISO (PMID:17310996) BHF-UCL PMID:17310996 NCBI chrNW_004955469:8,947,324...9,005,401
Ensembl chrNW_004955469:9,000,940...9,005,454
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:18593906) UniProt PMID:18593906 NCBI chrNW_004955437:5,940,825...5,945,367
Ensembl chrNW_004955437:5,942,106...5,945,431
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:19210544) BHF-UCL PMID:19210544 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO (PMID:11900540) UniProt PMID:11900540 NCBI chrNW_004955490:7,825,202...7,832,347
Ensembl chrNW_004955490:7,825,251...7,833,772
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in ISO (PMID:17310996) BHF-UCL PMID:17310996 NCBI chrNW_004955435:12,697,179...12,702,021
Ensembl chrNW_004955435:12,697,733...12,700,628
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:11687586)
(PMID:19162005)
BHF-UCL PMID:11687586 PMID:19162005 NCBI chrNW_004955518:4,788,857...4,800,273
Ensembl chrNW_004955518:4,788,656...4,801,204
JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A involved_in ISO (PMID:17151349)
(PMID:15611625)
AgBase
UniProt
PMID:15611625 PMID:17151349 NCBI chrNW_004955469:10,687,519...10,744,808
Ensembl chrNW_004955469:10,687,519...10,744,808
JBrowse link
G Stil STIL centriolar assembly protein acts_upstream_of_or_within ISO (PMID:16024801) MGI PMID:16024801 NCBI chrNW_004955464:11,213,265...11,288,648
Ensembl chrNW_004955464:11,228,667...11,289,648
JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor acts_upstream_of_or_within ISO (PMID:18323529) MGI PMID:18323529 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 involved_in ISO (PMID:15601624) UniProt PMID:15601624 NCBI chrNW_004955491:539,040...561,494
Ensembl chrNW_004955491:545,342...563,543
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO (PMID:12878610)
(PMID:12878610), (PMID:15579909)
MGI PMID:12878610 PMID:15579909 NCBI chrNW_004955442:16,845,728...16,898,301
Ensembl chrNW_004955442:16,843,152...16,898,430
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 acts_upstream_of ISO (PMID:16027136) BHF-UCL PMID:16027136 NCBI chrNW_004955472:1,444,598...1,446,488
Ensembl chrNW_004955472:1,444,316...1,446,490
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:12813029), (PMID:15310755)
(PMID:18281285)
BHF-UCL PMID:12813029 PMID:15310755 PMID:18281285 NCBI chrNW_004955419:6,229,437...6,416,619
Ensembl chrNW_004955419:6,228,591...6,416,402
JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) BHF-UCL PMID:11959862 NCBI chrNW_004955403:14,421,057...14,439,829
Ensembl chrNW_004955403:14,420,243...14,440,210
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (PMID:10829020)
(PMID:17593335)
BHF-UCL PMID:10829020 PMID:17593335 NCBI chrNW_004955467:9,675,912...9,683,996
Ensembl chrNW_004955467:9,675,912...9,683,996
JBrowse link
G Epha4 EPH receptor A4 involved_in ISO (PMID:10523642) BHF-UCL PMID:10523642 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:10650002) ParkinsonsUK-UCL PMID:10650002 NCBI chrNW_004955478:7,720,664...7,803,662
Ensembl chrNW_004955478:7,751,830...7,799,460
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (PMID:10650002) ParkinsonsUK-UCL PMID:10650002 NCBI chrNW_004955493:2,217,187...2,233,920
Ensembl chrNW_004955493:2,217,384...2,233,920
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173
JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 acts_upstream_of_or_within ISO (PMID:18838382) MGI PMID:18838382 NCBI chrNW_004955437:6,026,087...6,038,740
Ensembl chrNW_004955437:6,024,301...6,038,349
JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 acts_upstream_of_or_within ISO PMID:9668039 MGI PMID:9668039 RGD:1299389 NCBI chrNW_004955505:3,108,131...3,314,040
Ensembl chrNW_004955505:3,099,672...3,239,950
JBrowse link
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within ISO (PMID:15195140) MGI PMID:15195140 NCBI chrNW_004955414:6,094,585...6,103,910
Ensembl chrNW_004955414:6,094,585...6,098,865
JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within ISO (PMID:15195140) MGI PMID:15195140 NCBI chrNW_004955457:7,282,403...7,288,918
Ensembl chrNW_004955457:7,282,403...7,288,918
JBrowse link
G Fzd8 frizzled class receptor 8 acts_upstream_of_or_within ISO (PMID:15195140) MGI PMID:15195140 NCBI chrNW_004955462:5,870,410...5,873,714 JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 involved_in ISO (PMID:17379480) BHF-UCL PMID:17379480 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622
JBrowse link
G Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 acts_upstream_of_or_within ISO (PMID:15195140) MGI PMID:15195140 NCBI chrNW_004955435:16,735,598...16,974,005
Ensembl chrNW_004955435:16,735,598...16,972,204
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:11959862) BHF-UCL PMID:11959862 NCBI chrNW_004955563:1,352,638...1,361,598
Ensembl chrNW_004955563:1,352,638...1,361,598
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 involved_in ISO (PMID:10523642) RGD
BHF-UCL
PMID:9110999 PMID:10523642 RGD:2293488 NCBI chrNW_004955446:11,022,091...11,090,136
Ensembl chrNW_004955446:11,021,971...11,090,136
JBrowse link
G Map3k10 mitogen-activated protein kinase kinase kinase 10 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chrNW_004955578:1,018,280...1,037,553
Ensembl chrNW_004955578:1,018,560...1,036,901
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chrNW_004955422:19,651,371...19,666,468
Ensembl chrNW_004955422:19,651,372...19,667,924
JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 involved_in ISO (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chrNW_004955458:774,478...793,654
Ensembl chrNW_004955458:774,478...785,226
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chrNW_004955420:22,064,384...22,190,662
Ensembl chrNW_004955420:22,064,384...22,224,789
JBrowse link
G Map3k4 mitogen-activated protein kinase kinase kinase 4 involved_in
acts_upstream_of_or_within
ISO (PMID:16157600)
(PMID:12878610)
(PMID:9305639)
UniProt
MGI
PMID:9305639 PMID:12878610 PMID:16157600 NCBI chrNW_004955439:20,144,059...20,263,885
Ensembl chrNW_004955439:20,144,059...20,263,879
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:23000344) RGD
ParkinsonsUK-UCL
PMID:20716917 PMID:23000344 RGD:10412640 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:11460167) UniProt PMID:11460167 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957
JBrowse link
G Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chrNW_004955422:20,363,778...20,375,699
Ensembl chrNW_004955422:20,363,778...20,379,527
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 involved_in
acts_upstream_of_or_within
ISO (PMID:10523642)
(PMID:15767678)
BHF-UCL
MGI
PMID:10523642 PMID:15767678 NCBI chrNW_004955442:15,498,909...15,545,298
Ensembl chrNW_004955442:15,498,909...15,545,298
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISO (PMID:8805275) UniProt PMID:8805275 NCBI chrNW_004955414:14,365,325...14,447,470
Ensembl chrNW_004955414:14,365,157...14,450,611
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225
JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 acts_upstream_of ISO (PMID:15465829) ParkinsonsUK-UCL PMID:15465829 NCBI chrNW_004955445:7,754,313...7,819,229
Ensembl chrNW_004955445:7,754,319...7,819,275
JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774
JBrowse link
G Sash1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) MGI PMID:23776175 NCBI chrNW_004955439:12,551,361...12,729,500
Ensembl chrNW_004955439:12,550,273...12,839,896
JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link
G Taok3 TAO kinase 3 involved_in ISO (PMID:11278723) UniProt PMID:11278723 NCBI chrNW_004955455:13,020,618...13,207,539
Ensembl chrNW_004955455:13,103,357...13,211,315
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chrNW_004955407:30,804,769...31,178,420
Ensembl chrNW_004955407:30,803,653...30,942,854
JBrowse link
G Tlr6 toll like receptor 6 acts_upstream_of_or_within ISO (PMID:10231569) MGI PMID:10231569 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:17389591) UniProt PMID:17389591 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11a involved_in ISO (PMID:12296995) BHF-UCL PMID:12296995 NCBI chrNW_004955402:46,242,329...46,298,157
Ensembl chrNW_004955402:46,264,164...46,296,368
JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:11907583) UniProt PMID:11907583 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:11751921) BHF-UCL PMID:11751921 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:15195140) MGI PMID:15195140 NCBI chrNW_004955468:12,162,084...12,189,322
Ensembl chrNW_004955468:12,161,843...12,189,547
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (PMID:19300477)
(PMID:20034610)
MGI
BHF-UCL
PMID:19300477 PMID:20034610 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO (PMID:17644613) MGI PMID:17644613 NCBI chrNW_004955440:10,755,658...10,881,044
Ensembl chrNW_004955440:10,756,014...10,795,491
JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 acts_upstream_of ISO (PMID:17704059) BHF-UCL PMID:17704059 NCBI chrNW_004955463:14,545,425...14,646,498
Ensembl chrNW_004955463:14,545,589...14,645,419
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:19477270) BHF-UCL PMID:19477270 NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO (PMID:10330178) MGI PMID:10330178 NCBI chrNW_004955409:37,318,597...37,329,068
Ensembl chrNW_004955409:37,318,597...37,329,155
JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in ISO PMID:23716597 UniProt PMID:23716597 RGD:11059588 NCBI chrNW_004955416:19,006,206...19,327,523
Ensembl chrNW_004955416:19,009,485...19,247,626
JBrowse link
G Cd24 CD24 molecule involved_in ISO (PMID:12496407) UniProt PMID:12496407 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO PMID:11994468 MGI PMID:11994468 RGD:625644 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Cripto cripto, EGF-CFC family member acts_upstream_of_or_within ISO (PMID:9013573) MGI PMID:9013573 NCBI chrNW_004955420:25,476,975...25,479,969
Ensembl chrNW_004955420:25,477,122...25,479,969
JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550
JBrowse link
G Diras1 DIRAS family GTPase 1 NOT|involved_in ISO (PMID:12194967) UniProt PMID:12194967 NCBI chrNW_004955495:5,002,803...5,005,203
Ensembl chrNW_004955495:5,004,548...5,005,144
JBrowse link
G Diras2 DIRAS family GTPase 2 NOT|involved_in ISO (PMID:12194967) UniProt PMID:12194967 NCBI chrNW_004955515:1,526,436...1,551,811
Ensembl chrNW_004955515:1,526,333...1,551,811
JBrowse link
G Drd4 dopamine receptor D4 acts_upstream_of ISO (PMID:9843378) BHF-UCL PMID:9843378 NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:10770212) BHF-UCL PMID:10770212 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
JBrowse link
G Edn3 endothelin 3 involved_in ISO (PMID:10770212) BHF-UCL PMID:10770212 NCBI chrNW_004955445:215,910...238,153
Ensembl chrNW_004955445:215,859...237,760
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in ISO (PMID:10572067) UniProt PMID:10572067 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) UniProt PMID:20154697 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO (PMID:16756958) UniProt PMID:16756958 NCBI chrNW_004955415:11,151,330...11,245,554
Ensembl chrNW_004955415:11,151,266...11,247,344
JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in ISO (PMID:16756958) UniProt PMID:16756958 NCBI chrNW_004955408:24,225,459...24,260,057
Ensembl chrNW_004955408:24,225,459...24,260,092
JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:16756958) UniProt PMID:16756958 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 involved_in ISO (PMID:8622701) UniProt PMID:8622701 NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 involved_in ISO (PMID:9299537) UniProt PMID:9299537 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Gab1 GRB2 associated binding protein 1 acts_upstream_of_or_within ISO (PMID:12808090) MGI PMID:12808090 NCBI chrNW_004955471:61,580...191,175
Ensembl chrNW_004955471:61,120...191,175
JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) AgBase PMID:24313324 NCBI chrNW_004955408:4,234,208...4,239,795 JBrowse link
G Ghr growth hormone receptor acts_upstream_of ISO PMID:8063815 BHF-UCL PMID:8063815 RGD:8553732 NCBI chrNW_004955426:26,553,509...26,873,619
Ensembl chrNW_004955426:26,689,581...26,871,684
JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:26375174) MGI PMID:26375174 NCBI chrNW_004955440:46,648...235,644
Ensembl chrNW_004955440:47,652...239,206
JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) BHF-UCL PMID:23027131 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345
JBrowse link
G Il34 interleukin 34 acts_upstream_of_or_within ISO (PMID:26754294) ARUK-UCL PMID:26754294 NCBI chrNW_004955484:3,362,240...3,429,031
Ensembl chrNW_004955484:3,416,965...3,428,574
JBrowse link
G Ilk integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chrNW_004955414:22,316,243...22,322,979
Ensembl chrNW_004955414:22,316,047...22,322,979
JBrowse link
G Insr insulin receptor acts_upstream_of ISO (PMID:17001305) BHF-UCL PMID:17001305 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:23987506 RGD:11049533 NCBI chrNW_004955416:14,558,628...14,652,031
Ensembl chrNW_004955416:14,560,292...14,650,036
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 involved_in ISO (PMID:17379480) BHF-UCL PMID:17379480 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622
JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:10620616) MGI PMID:10620616 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (PMID:10620616) MGI PMID:10620616 NCBI chrNW_004955405:25,816,137...25,969,006
Ensembl chrNW_004955405:25,886,447...25,969,395
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:10969813 RGD:1600497 NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:21857923) ParkinsonsUK-UCL PMID:21857923 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Maged1 MAGE family member D1 involved_in ISO (PMID:19268530) UniProt PMID:19268530 NCBI chrNW_004955543:2,939,960...3,052,442
Ensembl chrNW_004955543:2,975,259...3,052,504
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 acts_upstream_of_or_within ISO (PMID:14744933) MGI PMID:14744933 NCBI chrNW_004955478:3,331,607...3,448,840
Ensembl chrNW_004955478:3,331,607...3,448,842
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chrNW_004955446:11,022,091...11,090,136
Ensembl chrNW_004955446:11,021,971...11,090,136
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:10364264) BHF-UCL PMID:10364264 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Mst1r macrophage stimulating 1 receptor involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chrNW_004955532:1,774,726...1,789,662
Ensembl chrNW_004955532:1,775,033...1,787,990
JBrowse link
G Nek10 NIMA related kinase 10 involved_in ISO (PMID:20956560) UniProt PMID:20956560 NCBI chrNW_004955430:18,754,292...18,988,716
Ensembl chrNW_004955430:18,754,292...18,988,771
JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (PMID:17942966) UniProt PMID:17942966 NCBI chrNW_004955414:4,062,337...4,220,032
Ensembl chrNW_004955414:4,062,081...4,212,746
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:17306762) MGI PMID:17306762 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:17360971) UniProt PMID:17360971 NCBI chrNW_004955448:16,866,577...16,887,215
Ensembl chrNW_004955448:16,864,031...16,887,626
JBrowse link
G Pde5a phosphodiesterase 5A involved_in ISO (PMID:19127022) BHF-UCL PMID:19127022 NCBI chrNW_004955428:20,785,497...20,904,717
Ensembl chrNW_004955428:20,785,423...20,904,717
JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO (PMID:11788434) UniProt PMID:11788434 NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO PMID:19460854
(PMID:11788434), (PMID:17942966), (PMID:9685360)
UniProt PMID:9685360 PMID:11788434 PMID:17942966 PMID:19460854 RGD:8554838 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:17942966) UniProt PMID:17942966 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma involved_in ISO (PMID:12507995) UniProt PMID:12507995 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422
JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 involved_in ISO (PMID:12507995) UniProt PMID:12507995 NCBI chrNW_004955467:8,025,231...8,091,406
Ensembl chrNW_004955467:8,065,857...8,091,486
JBrowse link
G Pik3r6 phosphoinositide-3-kinase regulatory subunit 6 involved_in ISO (PMID:19906996) UniProt PMID:19906996 NCBI chrNW_004955467:8,104,242...8,157,637
Ensembl chrNW_004955467:8,104,906...8,157,144
JBrowse link
G Pla2g1b phospholipase A2 group IB acts_upstream_of ISO (PMID:16005851) BHF-UCL PMID:16005851 NCBI chrNW_004955455:11,308,848...11,316,245
Ensembl chrNW_004955455:11,308,643...11,316,254
JBrowse link
G Prkcd protein kinase C delta ISO RGD PMID:16935468 RGD:1642549 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:15896720) MGI PMID:15896720 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:15899849) CACAO PMID:15899849 NCBI chrNW_004955416:5,494,030...5,561,608
Ensembl chrNW_004955416:5,494,030...5,561,614
JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:21385766) BHF-UCL PMID:21385766 NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:11941412 RGD:150523765 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chrNW_004955413:25,290,733...25,315,267
Ensembl chrNW_004955413:25,290,828...25,313,969
JBrowse link
G Tenm1 teneurin transmembrane protein 1 involved_in ISO (PMID:22698694) UniProt PMID:22698694 NCBI chrNW_004955473:9,557,822...10,342,007
Ensembl chrNW_004955473:9,770,364...10,337,379
JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of ISO (PMID:17413041) BHF-UCL PMID:17413041 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of ISO (PMID:20051628) BHF-UCL PMID:20051628 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:12813029), (PMID:17389591) UniProt PMID:12813029 PMID:17389591 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (PMID:15304486) BHF-UCL PMID:15304486 NCBI chrNW_004955518:431,401...462,063
Ensembl chrNW_004955518:430,642...462,705
JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO (PMID:14761963) UniProt PMID:14761963 NCBI chrNW_004955436:6,648,140...6,672,474
Ensembl chrNW_004955436:6,602,051...6,671,978
JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (PMID:23775122) MGI PMID:23775122 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISO (PMID:23990668) UniProt PMID:23990668 NCBI chrNW_004955416:11,562,047...11,699,925
Ensembl chrNW_004955416:11,613,316...11,699,925
JBrowse link
G Dipk2a divergent protein kinase domain 2A involved_in ISO (PMID:24269490) GO_Central PMID:24269490 NCBI chrNW_004955508:1,954,600...1,975,842
Ensembl chrNW_004955508:1,953,923...1,975,842
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774
JBrowse link
G Tcim transcriptional and immune response regulator involved_in ISO (PMID:15087392) CAFA PMID:15087392 NCBI chrNW_004955536:2,786,384...2,786,988
Ensembl chrNW_004955536:2,786,482...2,786,799
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:12086864) CACAO PMID:12086864 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12563
    biological regulation 9078
      regulation of molecular function 1486
        regulation of catalytic activity 954
          regulation of transferase activity 539
            regulation of kinase activity 480
              regulation of protein kinase activity 447
                positive regulation of protein kinase activity 269
                  positive regulation of protein serine/threonine kinase activity 150
                    positive regulation of MAP kinase activity + 109
                    positive regulation of cAMP-dependent protein kinase activity 5
                    positive regulation of cyclin-dependent protein serine/threonine kinase activity 13
                    positive regulation of protein kinase C activity 7
Path 2
Term Annotations click to browse term
  biological_process 12563
    biological regulation 9078
      regulation of biological process 8773
        regulation of cellular process 8486
          regulation of metabolic process 5016
            regulation of macromolecule metabolic process 4537
              regulation of protein metabolic process 1705
                regulation of protein modification process 1053
                  regulation of protein phosphorylation 809
                    positive regulation of protein phosphorylation 513
                      positive regulation of protein kinase activity 269
                        positive regulation of protein serine/threonine kinase activity 150
                          positive regulation of MAP kinase activity + 109
                          positive regulation of cAMP-dependent protein kinase activity 5
                          positive regulation of cyclin-dependent protein serine/threonine kinase activity 13
                          positive regulation of protein kinase C activity 7
paths to the root