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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of protein serine/threonine kinase activity
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Accession:GO:0071900 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.


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negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO RGD PMID:10721722 RGD:632478 NCBI chr 1:260,465,809...260,648,070
Ensembl chr 1:260,466,942...260,648,161 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO RGD PMID:10721722 RGD:632478 NCBI chr12:24,224,262...24,234,468
Ensembl chr12:24,224,263...24,234,467 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:22584582 RGD:10045364 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 ISO RGD PMID:12064607 RGD:1299562 NCBI chr 2:16,562,687...16,584,763
Ensembl chr 2:16,564,257...16,584,768 		JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17182785 RGD:2301767 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 RGD:10044039 NCBI chr 2:40,458,865...40,521,470
Ensembl chr 2:40,459,049...40,521,461 		JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:14612383 RGD:1580517 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,925...39,937,371 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC6 cell division cycle 6 ISO RGD PMID:22223646 RGD:10045360 NCBI chr12:22,101,281...22,118,441
Ensembl chr12:22,101,282...22,118,593 		JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:36,877,570...36,911,344
Ensembl chr17:36,877,650...36,908,019 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:22223646 RGD:10045360 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684
G LOC110258578 interleukin-1 beta-like ISO RGD PMID:12667655 RGD:1626684
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,493 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr14:2,803,840...3,035,384
Ensembl chr14:2,804,061...3,035,296 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089 		JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chr 7:58,736,473...58,755,034
Ensembl chr 7:58,736,531...58,755,260 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,963...20,619,625 		JBrowse link
G ILK integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:10969813 RGD:1600497 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987 		JBrowse link
G PRKCD protein kinase C delta ISO RGD PMID:16935468 RGD:1642549 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:11941412 RGD:150523765 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chr 5:8,827,363...8,852,814
Ensembl chr 5:8,826,840...8,852,776 		JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:16341931 RGD:9685306 NCBI chr 1:79,789,796...79,795,895
Ensembl chr 1:79,789,815...79,795,760 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr14:2,803,840...3,035,384
Ensembl chr14:2,804,061...3,035,296 		JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481 		JBrowse link
regulation of Rho-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2 DAB adaptor protein 2 ISO RGD PMID:9681506 RGD:728288 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of molecular function 303
        regulation of catalytic activity 186
          regulation of transferase activity 66
            regulation of kinase activity 64
              regulation of protein kinase activity 57
                regulation of protein serine/threonine kinase activity 28
                  negative regulation of protein serine/threonine kinase activity + 8
                  positive regulation of protein serine/threonine kinase activity + 20
                  regulation of MAP kinase activity + 19
                  regulation of Rho-dependent protein serine/threonine kinase activity + 1
                  regulation of cAMP-dependent protein kinase activity + 1
                  regulation of cyclin-dependent protein serine/threonine kinase activity + 5
                  regulation of myosin light chain kinase activity + 0
                  regulation of protein kinase C activity + 2
Path 2
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of biological process 12533
        regulation of metabolic process 6217
          regulation of cellular metabolic process 5603
            regulation of phosphorus metabolic process 914
              regulation of phosphate metabolic process 911
                regulation of phosphorylation 747
                  regulation of kinase activity 64
                    regulation of protein kinase activity 57
                      regulation of protein serine/threonine kinase activity 28
                        negative regulation of protein serine/threonine kinase activity + 8
                        positive regulation of protein serine/threonine kinase activity + 20
                        regulation of MAP kinase activity + 19
                        regulation of Rho-dependent protein serine/threonine kinase activity + 1
                        regulation of cAMP-dependent protein kinase activity + 1
                        regulation of cyclin-dependent protein serine/threonine kinase activity + 5
                        regulation of myosin light chain kinase activity + 0
                        regulation of protein kinase C activity + 2
paths to the root