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ONTOLOGY REPORT - ANNOTATIONS


Term:odontoblast differentiation
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Accession:GO:0071895 term browser browse the term
Definition:The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.



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odontoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLX3 distal-less homeobox 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22351765) Ensembl
MGI
PMID:22351765 GO_REF:0000107 NCBI chr17:44,076,437...44,081,690
Ensembl chr17:48,950,474...48,955,848
JBrowse link
G DSPP dentin sialophosphoprotein acts_upstream_of_or_within ISO (PMID:25027178) RGD
MGI
PMID:15763925 PMID:25027178 RGD:12911014 NCBI chr 4:79,903,923...79,909,836 JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251) RGD
MGI
PMID:17369251 RGD:11560522 NCBI chr 7:311,468...394,623 JBrowse link
G IFT80 intraflagellar transport 80 acts_upstream_of_or_within ISO (PMID:30683845) MGI PMID:30683845 NCBI chr 3:157,279,076...157,421,478
Ensembl chr 3:165,329,056...165,454,905
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO RGD PMID:20425127 RGD:4110819 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G MAP1B microtubule associated protein 1B acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:19567321) GO_Central
Ensembl
PMID:19567321 GO_REF:0000107 NCBI chr 5:43,102,739...43,204,978
Ensembl chr 5:43,701,530...43,803,393
JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TUBB tubulin beta class I acts_upstream_of_or_within ISO (PMID:19567321) GO_Central PMID:19567321 NCBI chr 6:30,465,367...30,470,451 JBrowse link
negative regulation of odontoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSX1 msh homeobox 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:4,935,600...4,939,079 JBrowse link
positive regulation of odontoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G CTNNB1 catenin beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G IPO7 importin 7 involved_in ISO (MGI:7510301|PMID:35922041) UniProt PMID:35922041 MGI:7510301 NCBI chr11:9,521,055...9,583,638
Ensembl chr11:9,256,060...9,318,333
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 involved_in ISO (MGI:6313943|PMID:30984011) UniProt PMID:30984011 MGI:6313943 NCBI chr17:74,973,420...75,389,339
Ensembl chr17:80,705,544...81,118,708
JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
regulation of odontoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISO PMID:15308669 UniProt PMID:15308669 RGD:1599801 NCBI chr20:46,533,163...46,535,282 JBrowse link
G DSPP dentin sialophosphoprotein involved_in ISO PMID:15308669 UniProt PMID:15308669 RGD:1599801 NCBI chr 4:79,903,923...79,909,836 JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 involved_in ISO (PMID:15308669) UniProt PMID:15308669 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cellular developmental process 4393
        cell differentiation 4392
          epithelial cell differentiation 800
            columnar/cuboidal epithelial cell differentiation 145
              neuroepithelial cell differentiation 50
                odontoblast differentiation 18
                  negative regulation of odontoblast differentiation 1
                  positive regulation of odontoblast differentiation 7
                  regulation of odontoblast differentiation + 11
Path 2
Term Annotations click to browse term
  biological_process 16313
    developmental process 6551
      anatomical structure development 6160
        tissue development 2183
          epithelium development 1376
            epithelial cell differentiation 800
              columnar/cuboidal epithelial cell differentiation 145
                neuroepithelial cell differentiation 50
                  odontoblast differentiation 18
                    negative regulation of odontoblast differentiation 1
                    positive regulation of odontoblast differentiation 7
                    regulation of odontoblast differentiation + 11
paths to the root