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ONTOLOGY REPORT - ANNOTATIONS

Term:podosome assembly
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Accession:GO:0071800 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.


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podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASB2 ankyrin repeat and SOCS box containing 2 involved_in ISO (MGI:5510317|PMID:23632887) UniProt PMID:23632887 MGI:5510317 NCBI chr14:74,566,607...74,608,905
Ensembl chr14:93,900,914...93,930,527 		JBrowse link
G BIN2 bridging integrator 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:37,430,061...37,473,182
Ensembl chr12:38,314,126...38,357,264 		JBrowse link
G DBNL drebrin like involved_in ISO (MGI:5487508|PMID:22303001) UniProt PMID:22303001 MGI:5487508 NCBI chr 7:44,753,062...44,775,717
Ensembl chr 7:44,824,608...44,845,891 		JBrowse link
G DIAPH3 diaphanous related formin 3 acts_upstream_of_or_within ISO (PMID:15976449) MGI PMID:15976449 NCBI chr13:40,846,270...41,335,920
Ensembl chr13:59,676,307...60,056,672 		JBrowse link
G DOCK5 dedicator of cytokinesis 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27505886) Ensembl
MGI		 PMID:27505886 GO_REF:0000107 NCBI chr 8:24,463,582...24,696,736
Ensembl chr 8:21,372,756...21,605,877 		JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,627,208...128,766,233
Ensembl chr2B:247,438,265...247,559,735 		JBrowse link
G RHO rhodopsin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15976449) Ensembl
MGI		 PMID:15976449 GO_REF:0000107 NCBI chr 3:126,586,510...126,593,028
Ensembl chr 3:133,938,419...133,944,928 		JBrowse link
G SH3PXD2B SH3 and PX domains 2B involved_in ISO (MGI:4943661|PMID:19144821) UniProt PMID:19144821 MGI:4943661 NCBI chr 5:167,678,633...167,807,960
Ensembl chr 5:174,591,759...174,719,957 		JBrowse link
G TNS3 tensin 3 acts_upstream_of_or_within ISO (PMID:27505886) MGI PMID:27505886 NCBI chr 7:47,915,668...48,223,267
Ensembl chr 7:48,025,720...48,221,437 		JBrowse link
negative regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO (PMID:21352810) MGI PMID:21352810 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
positive regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF5 Rho guanine nucleotide exchange factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21525037) Ensembl
MGI		 PMID:21525037 GO_REF:0000107 NCBI chr 7:136,069,598...136,094,866
Ensembl chr 7:148,558,803...148,584,078 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:17224451 RGD:2306207 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643 		JBrowse link
G CAPG capping actin protein, gelsolin like NOT|involved_in ISO (PMID:24236012) UniProt PMID:24236012 NCBI chr2A:85,447,296...85,466,677
Ensembl chr2A:86,997,891...87,016,263 		JBrowse link
G CSF2 colony stimulating factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in ISO (PMID:20137952) UniProt PMID:20137952 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G IL5 interleukin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,820,846...26,906,916 JBrowse link
G MAPK8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO (PMID:24127566) MGI PMID:24127566 NCBI chr10:45,806,748...45,936,362 JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24127566) Ensembl
MGI		 PMID:24127566 GO_REF:0000107 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G MSN moesin acts_upstream_of_or_within ISO (PMID:24127566) MGI PMID:24127566 NCBI chr  X:54,785,309...54,859,364
Ensembl chr  X:64,781,550...64,933,292 		JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO RGD PMID:16868024 RGD:2325783 NCBI chr 4:160,718,475...161,140,436 JBrowse link
G RHOA ras homolog family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21525037) Ensembl
MGI		 PMID:21525037 GO_REF:0000107 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21525037), (PMID:24127566) Ensembl
MGI		 PMID:21525037 PMID:24127566 GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:28,346,244...28,395,370
Ensembl chr20:29,474,737...29,523,399 		JBrowse link
G KIF9 kinesin family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,130,047...47,183,636
Ensembl chr 3:48,229,703...48,283,002 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          cellular component assembly 3007
            protein-containing complex assembly 1519
              podosome assembly 27
                negative regulation of podosome assembly 1
                positive regulation of podosome assembly 14
                regulation of podosome assembly + 18
Path 2
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          cellular component assembly 3007
            organelle assembly 1026
              non-membrane-bounded organelle assembly 429
                podosome assembly 27
                  negative regulation of podosome assembly 1
                  positive regulation of podosome assembly 14
                  regulation of podosome assembly + 18
paths to the root