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ONTOLOGY REPORT - ANNOTATIONS


Term:podosome assembly
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Accession:GO:0071800 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.



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podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISO (MGI:5510317|PMID:23632887) RGD PMID:23632887 MGI:5510317 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Bin2 bridging integrator 2 involved_in ISO
IBA
ISS
(PMID:23285027)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23285027 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:131,742,001...131,768,208
Ensembl chr 7:131,742,002...131,786,285
JBrowse link
G Dbnl drebrin-like involved_in ISS
ISO
GO_REF:0000024
(MGI:5487508|PMID:22303001)
UniProt
RGD
PMID:22303001 GO_REF:0000024 MGI:5487508 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155
JBrowse link
G Dock5 dedicator of cytokinesis 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5923408|PMID:27505886)
GO_REF:0000107
RGD
Ensembl
PMID:27505886 GO_REF:0000107 MGI:5923408 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 involved_in ISO (MGI:4844210|PMID:20702777) RGD PMID:20702777 MGI:4844210 NCBI chr 9:94,053,650...94,162,212
Ensembl chr 9:94,053,726...94,162,212
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B involved_in ISO (MGI:4943661|PMID:19144821) RGD PMID:19144821 MGI:4943661 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
JBrowse link
G Tns3 tensin 3 acts_upstream_of_or_within ISO (MGI:5923408|PMID:27505886) RGD PMID:27505886 MGI:5923408 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
JBrowse link
negative regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO (MGI:5002438|PMID:21352810) RGD PMID:21352810 MGI:5002438 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
positive regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef5 Rho guanine nucleotide exchange factor 5 acts_upstream_of_or_within ISO MGI:1096342|MGI:98397 (MGI:5317222|PMID:21525037) RGD PMID:21525037 MGI:5317222 NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:17224451 RGD:2306207 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3768569|PMID:17893324)
RGD PMID:17893324 PMID:21873635 MGI:3768569, RGD:13792537 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754
JBrowse link
G Capg capping actin protein, gelsolin like NOT|involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:15220135) RGD PMID:15220135 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20137952)
UniProt
RGD
PMID:20137952 GO_REF:0000024 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Il5 interleukin 5 involved_in ISO (PMID:15220135) RGD PMID:15220135 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO (MGI:5576866|PMID:24127566) RGD PMID:24127566 MGI:5576866 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of_or_within ISO (MGI:5576866|PMID:24127566) RGD PMID:24127566 MGI:5576866 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Msn moesin acts_upstream_of_or_within ISO (MGI:5576866|PMID:24127566) RGD PMID:24127566 MGI:5576866 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Palld palladin, cytoskeletal associated protein IMP RGD PMID:16868024 RGD:2325783 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO MGI:1858952|MGI:98397 (MGI:5317222|PMID:21525037) RGD PMID:21525037 MGI:5317222 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1096342|MGI:1858952 (MGI:5317222|PMID:21525037), (MGI:5576866|PMID:24127566) RGD PMID:21525037 PMID:24127566 MGI:5317222 MGI:5576866 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:15220135) RGD PMID:15220135 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
regulation of podosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase involved_in ISO
ISS
(PMID:15998323)
GO_REF:0000024
RGD
UniProt
PMID:15998323 GO_REF:0000024 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Kif9 kinesin family member 9 involved_in ISO (PMID:21119006) RGD PMID:21119006 NCBI chr 8:110,459,467...110,504,492
Ensembl chr 8:110,459,383...110,505,252
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    cellular process 18675
      cellular component organization or biogenesis 6788
        cellular component organization 6542
          cellular component assembly 3073
            protein-containing complex assembly 1623
              podosome assembly 26
                negative regulation of podosome assembly 1
                positive regulation of podosome assembly 15
                regulation of podosome assembly + 19
Path 2
Term Annotations click to browse term
  biological_process 20091
    cellular process 18675
      cellular component organization or biogenesis 6788
        cellular component organization 6542
          cellular component assembly 3073
            organelle assembly 1006
              non-membrane-bounded organelle assembly 430
                podosome assembly 26
                  negative regulation of podosome assembly 1
                  positive regulation of podosome assembly 15
                  regulation of podosome assembly + 19
paths to the root