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ONTOLOGY REPORT - ANNOTATIONS


Term:tumor necrosis factor superfamily cytokine production
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Accession:GO:0071706 term browser browse the term
Definition:The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:exact_synonym: TNFSF cytokine production
 related_synonym: TNF superfamily production



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negative regulation of tumor necrosis factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO MGI:2180086 (MGI:1930064|PMID:11168643) RGD PMID:11168643 MGI:1930064 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:10961870)
GO_REF:0000024
RGD
UniProt
PMID:10961870 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:11096136 RGD:8548521 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Akap8 A-kinase anchoring protein 8 involved_in ISO (MGI:5763364|PMID:19531803) RGD PMID:19531803 MGI:5763364 NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399
JBrowse link
G Arg2 arginase 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5908771|PMID:27074721)
(PMID:28614294)
Ensembl
RGD
PMID:27074721 PMID:28614294 GO_REF:0000107 MGI:5908771 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO (MGI:3662828|PMID:16378096) RGD PMID:16378096 MGI:3662828 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:107670 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO (MGI:3522403|PMID:15465827) RGD PMID:15465827 MGI:3522403 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bpi bactericidal/permeability-increasing protein involved_in ISO
IBA
(PMID:8409400)
PMID:21873635
RGD PMID:8409400 PMID:21873635 RGD:13792537 NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
JBrowse link
G C5ar2 complement C5a receptor 2 involved_in ISO
ISS
(PMID:16204243)
GO_REF:0000024
RGD
UniProt
PMID:16204243 GO_REF:0000024 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517
JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829
JBrowse link
G Cd24 CD24 molecule involved_in ISO (MGI:5913663|PMID:19264983) RGD PMID:19264983 MGI:5913663 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd33 CD33 molecule involved_in ISO (PMID:15597323) RGD PMID:15597323 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149
JBrowse link
G Cd34 CD34 molecule involved_in ISO
ISS
(PMID:17505307)
GO_REF:0000024
RGD
UniProt
PMID:17505307 GO_REF:0000024 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12508119)
MGI:1888407 (MGI:3040787|PMID:12508119), (MGI:3721478|PMID:16785311)
Ensembl
RGD
PMID:12508119 PMID:16785311 GO_REF:0000107 MGI:3040787 MGI:3721478 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (PMID:15919794) RGD PMID:15919794 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Clec4a C-type lectin domain family 4, member A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 involved_in ISO (PMID:18258799) RGD PMID:18258799 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA
(PMID:10652441)
GO_REF:0000107
RGD
Ensembl
PMID:10652441 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IMP RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:3628823 (MGI:4452060|PMID:20457904) RGD PMID:20457904 MGI:4452060 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS
(PMID:19657094), (PMID:20103767)
GO_REF:0000024
RGD
UniProt
PMID:19657094 PMID:20103767 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in IDA
ISS
ISO
GO_REF:0000024
(PMID:15232612)
UniProt
RGD
PMID:15232612 PMID:19620309 GO_REF:0000024, RGD:12905041 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in IMP
ISS
ISO
GO_REF:0000024
(PMID:15232612)
UniProt
RGD
PMID:15232612 PMID:17911350 GO_REF:0000024, RGD:12907501 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (MGI:3836695|PMID:17475886) RGD PMID:17475886 MGI:3836695 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO MGI:5708707 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009376|PMID:18962899), (MGI:5009411|PMID:16023107)
(PMID:18962899)
BHF-UCL
RGD
PMID:16023107 PMID:18962899 GO_REF:0000024 MGI:5009376 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO UniProtKB:O00182 (PMID:25578313) RGD PMID:25578313 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hdac3 histone deacetylase 3 IMP RGD PMID:22772764 RGD:9590127 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hsf1 heat shock transcription factor 1 acts_upstream_of_or_within ISO MGI:2155444 (MGI:1347429|PMID:10545106) RGD PMID:10545106 MGI:1347429 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107
RGD
Ensembl
PMID:27277332 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il10 interleukin 10 acts_upstream_of_or_within IDA
ISO
MGI:1857199 (MGI:3774790|PMID:12452830) RGD PMID:12452830 PMID:17017555 MGI:3774790, RGD:1598631 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in ISO UniProtKB:P35951 (MGI:5581894|PMID:22927332) RGD PMID:22927332 MGI:5581894 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) RGD PMID:29061364 MGI:6304699 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in ISO (PMID:29802199) RGD PMID:29802199 NCBI chr20:5,809,931...5,876,231
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO
IBA
(PMID:15728517)
(MGI:2183694|PMID:12150927)
PMID:21873635
RGD PMID:12150927 PMID:15728517 PMID:21873635 MGI:2183694, RGD:13792537 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:11739189) RGD PMID:11739189 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q8TDQ0 (PMID:25578313) RGD PMID:25578313 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19833736) RGD PMID:19833736 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Mc1r melanocortin 1 receptor involved_in ISO (PMID:10233018) RGD PMID:10233018 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Mir101-2 microRNA 101-2 acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
JBrowse link
G Mir101a microRNA 101a acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
JBrowse link
G Mir105 microRNA 105 acts_upstream_of ISO (PMID:19509287) RGD PMID:19509287 NCBI chr  X:150,438,529...150,438,601
Ensembl chr  X:150,438,529...150,438,601
JBrowse link
G Mir125b1 microRNA 125b-1 involved_in ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir125b2 microRNA 125b-2 involved_in ISO (PMID:26435691) RGD PMID:26435691 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir130a microRNA 130a involved_in ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir140 microRNA 140 acts_upstream_of ISO (PMID:30321456) RGD PMID:30321456 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir154 microRNA 154 IMP RGD PMID:31746418 RGD:152995474 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23516523) RGD PMID:23516523 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961
JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO (PMID:24803541) RGD PMID:24803541 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir204 microRNA 204 acts_upstream_of ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mir488 microRNA 488 involved_in ISO (PMID:28915828) RGD PMID:28915828 NCBI chr13:70,683,064...70,683,142
Ensembl chr13:70,683,064...70,683,142
JBrowse link
G Mir708 microRNA 708 acts_upstream_of ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963
JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:31886314) RGD PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20829348)
UniProt
RGD
PMID:20829348 GO_REF:0000024 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:22863753)
(MGI:5437524|PMID:22863753)
RGD PMID:22863753 MGI:5437524 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (MGI:3839525|PMID:19139201) RGD PMID:19139201 MGI:3839525 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA
(PMID:21242261)
GO_REF:0000107
(MGI:5707586|PMID:18972444)
RGD
Ensembl
PMID:18972444 PMID:21242261 GO_REF:0000107 MGI:5707586 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Orm1 orosomucoid 1 involved_in ISO (PMID:23973664) RGD PMID:23973664 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Pomc proopiomelanocortin involved_in ISO
IEA
(PMID:10233018)
GO_REF:0000107
RGD
Ensembl
PMID:10233018 GO_REF:0000107 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:15560120 RGD:10043380 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO
IBA
(PMID:23991106)
(MGI:5640942|PMID:23991106)
PMID:21873635
RGD PMID:23991106 PMID:21873635 MGI:5640942, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P97797 (MGI:3760575|PMID:17954568)
Ensembl
RGD
PMID:17954568 GO_REF:0000107 MGI:3760575 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO (PMID:18416830) RGD PMID:18416830 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Selenos selenoprotein S involved_in IEA
ISO
GO_REF:0000107
(MGI:3773781|PMID:16227999)
Ensembl
RGD
PMID:16227999 GO_REF:0000107 MGI:3773781 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:19299582 RGD:9585771 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:16317102) RGD PMID:16317102 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Syt11 synaptotagmin 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:5468041|PMID:23303671), (MGI:5780534|PMID:25063865), (MGI:5913303|PMID:28686317)
UniProt
RGD
PMID:23303671 PMID:25063865 PMID:28686317 GO_REF:0000024 MGI:5468041 MGI:5780534 MGI:5913303 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4421230|PMID:20051628)
Ensembl
RGD
PMID:20051628 GO_REF:0000107 MGI:4421230 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO ComplexPortal:CPX-1134 (MGI:5307186|PMID:22198949) RGD PMID:22198949 MGI:5307186 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4946158|PMID:21088135) RGD PMID:21088135 MGI:4946158 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294162|PMID:28592261) RGD PMID:28592261 MGI:6294162 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trim27 tripartite motif-containing 27 involved_in ISO (PMID:22128329) RGD PMID:22128329 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
JBrowse link
G Tspo translocator protein IDA RGD PMID:14678758 RGD:2317158 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104685 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:3044412|MGI:98872 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:5142149|PMID:21616078)
(PMID:18178554)
UniProt
RGD
PMID:18178554 PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
negative regulation of tumor necrosis factor superfamily cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:24187568) RGD PMID:24187568 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
positive regulation of lymphotoxin A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17f interleukin 17F involved_in ISO
IEA
(PMID:11591732)
GO_REF:0000107
RGD
Ensembl
PMID:11591732 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482
JBrowse link
positive regulation of TRAIL production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 involved_in ISO (PMID:16108830) RGD PMID:16108830 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009349|PMID:20683884) RGD PMID:20683884 MGI:5009349 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Ccn1 cellular communication network factor 1 IMP RGD PMID:27653023 RGD:150429754 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16220542) RGD PMID:16220542 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
positive regulation of tumor necrosis factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:18854840 RGD:2325137 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO UniProtKB:P05067 (MGI:5424311|PMID:22406537) RGD PMID:22406537 MGI:5424311 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:19937403 PMID:17873284 RGD:14348968, RGD:14348969 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P49768|UniProtKB:Q62151|UniProtKB:Q9QUN7 (PMID:22198949), (PMID:22406537), (PMID:29061364)
UniProtKB:Q62151 (PMID:12808450)
UniProtKB:Q62151 (MGI:6271381|PMID:12808450)
RGD PMID:12808450 PMID:22198949 PMID:22406537 PMID:29061364 MGI:6271381 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17276987)
UniProt
RGD
PMID:17276987 GO_REF:0000024 NCBI chr 3:155,547,504...155,633,652
Ensembl chr 3:155,547,538...155,630,856
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21887730)
UniProt
Ensembl
RGD
PMID:21887730 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5887181|PMID:27671645) RGD PMID:27671645 MGI:5887181 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G C1qtnf4 C1q and TNF related 4 involved_in ISO (PMID:21658842) RGD PMID:21658842 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:24826069 RGD:8661667 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P22893 (MGI:5301204|PMID:21784977)
UniProt
RGD
PMID:21784977 GO_REF:0000024 MGI:5301204 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IMP RGD PMID:10679105 RGD:68880 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccn1 cellular communication network factor 1 IMP RGD PMID:27653023 RGD:150429754 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in IMP
ISO
ISS
(MGI:3814510|PMID:18832716)
GO_REF:0000024
RGD
BHF-UCL
PMID:18832716 PMID:24826069 GO_REF:0000024 MGI:3814510, RGD:8661667 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IMP RGD PMID:16790532 RGD:1598562 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd14 CD14 molecule involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:12594207)
(PMID:15294986), (PMID:8612135)
(MGI:80217|PMID:8612135)
UniProt
RGD
PMID:8612135 PMID:12594207 PMID:15294986 GO_REF:0000024 MGI:80217 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd2 Cd2 molecule involved_in ISO (PMID:19109405) RGD PMID:19109405 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
JBrowse link
G Cd36 CD36 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2447190|MGI:3573941 (MGI:3528769|PMID:15690042), (MGI:3587138|PMID:16061696)
GO_REF:0000107
RGD
Ensembl
PMID:15690042 PMID:16061696 GO_REF:0000107 MGI:3528769 MGI:3587138 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd36-ps1 CD36 molecule, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,487,837...17,514,900 JBrowse link
G Cd84 CD84 molecule involved_in ISO
IBA
(MGI:5700297|PMID:20628063)
PMID:21873635
RGD PMID:20628063 PMID:21873635 MGI:5700297, RGD:13792537 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Clec4m C-type lectin domain family 4 member M acts_upstream_of_or_within ISO (MGI:3027358|PMID:14707091) RGD PMID:14707091 MGI:3027358 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539
JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within
ISO (PMID:19358895)
(MGI:3027358|PMID:14707091), (MGI:3042099|PMID:12719478)
RGD PMID:12719478 PMID:14707091 PMID:19358895 MGI:3027358 MGI:3042099 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Clu clusterin involved_in ISO
ISS
IEA
(PMID:15857407)
GO_REF:0000024
GO_REF:0000107
RGD
Alzheimers_University_of_Toronto
Ensembl
PMID:15857407 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:18434589 RGD:151665814 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in ISO (PMID:22423966) RGD PMID:22423966 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain IMP RGD PMID:19318376 RGD:11040691 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IMP RGD PMID:25840911 PMID:29656108 RGD:12904676, RGD:150520032 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Ddt D-dopachrome tautomerase involved_in ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
JBrowse link
G Ddx58 DEXD/H-box helicase 58 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:20696886), (PMID:21957149) RGD PMID:20696886 PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (PMID:24803541) RGD PMID:24803541 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165|MGI:2384004 (MGI:2383976|PMID:10229794), (MGI:3029067|PMID:14764707) RGD PMID:10229794 PMID:14764707 MGI:2383976 MGI:3029067 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (MGI:2383976|PMID:10229794) RGD PMID:10229794 MGI:2383976 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:10728755) RGD PMID:10728755 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Frmd8 FERM domain containing 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:29897333), (PMID:29897336)
UniProt
RGD
PMID:29897333 PMID:29897336 GO_REF:0000024 NCBI chr 1:203,143,216...203,163,868
Ensembl chr 1:203,143,218...203,163,870
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in IEA
ISO
GO_REF:0000107
ComplexPortal:CPX-1134|UniProtKB:P22725 (MGI:5291547|PMID:21857966)
Ensembl
RGD
PMID:21857966 GO_REF:0000107 MGI:5291547 NCBI chr 9:66,117,370...66,119,127
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:18006747)
(MGI:3763563|PMID:18006747)
RGD PMID:18006747 MGI:3763563 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:22772764 RGD:9590127 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:22772764 RGD:9590127 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hmgb1 high mobility group box 1 involved_in IMP
ISO
IDA
(PMID:12765338)
PMID:10952726
(MGI:4367121|PMID:19890330), (MGI:5913663|PMID:19264983)
RGD PMID:12765338 PMID:19264983 PMID:19890330 PMID:22514737 PMID:10952726 MGI:4367121 MGI:5913663, RGD:10402175, RGD:10054071 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5050077|PMID:12385642)
Ensembl
RGD
PMID:12385642 GO_REF:0000107 MGI:5050077 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IMP RGD PMID:23447644 RGD:10402845 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifng interferon gamma involved_in ISO ComplexPortal:CPX-1062|UniProtKB:P05067|UniProtKB:P15261|UniProtKB:P49768 (MGI:3697769|PMID:17255335), (MGI:4942276|PMID:2502420), (MGI:4943415|PMID:1845803), (MGI:5776417|PMID:26227742), (MGI:6304699|PMID:29061364), (MGI:6305053|PMID:7715705) RGD PMID:1845803 PMID:2502420 PMID:7715705 PMID:17255335 PMID:26227742 More... MGI:3697769 MGI:4942276 MGI:4943415 MGI:5776417 MGI:6304699 MGI:6305053 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P01579 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16751425) RGD PMID:16751425 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il17a interleukin 17A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:29734196)
Ensembl
RGD
PMID:29734196 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 IMP RGD PMID:17623049 RGD:4889480 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of IMP PMID:31172560 ARUK-UCL PMID:31172560 RGD:15023467 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:16751425) RGD PMID:16751425 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:6414704|PMID:26936882)
Ensembl
RGD
PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within
involved_in
ISO RNAcentral:URS00004E0808_9606 (PMID:31886314) RGD PMID:31886314 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO (MGI:5437583|PMID:22727192) RGD PMID:22727192 MGI:5437583 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO UniProtKB:P01580 (MGI:5009182|PMID:12426001), (MGI:5776417|PMID:26227742) RGD PMID:12426001 PMID:26227742 MGI:5009182 MGI:5776417 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:12594207)
(PMID:24120359), (PMID:8409400)
(MGI:1097829|PMID:9338787), (MGI:3807766|PMID:12932360), (MGI:5645195|PMID:24380872)
MGI:1857975 (MGI:3719540|PMID:12055258)
UniProt
RGD
PMID:8409400 PMID:9338787 PMID:12055258 PMID:12594207 PMID:12932360 More... GO_REF:0000024 MGI:1097829 MGI:3719540 MGI:3807766 MGI:5645195 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lep leptin involved_in ISS
ISO
GO_REF:0000024
(MGI:3690675|PMID:9438411)
UniProt
RGD
PMID:9438411 GO_REF:0000024 MGI:3690675 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097)
(MGI:5645190|PMID:25158758)
RGD PMID:20209097 PMID:25158758 MGI:5645190 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 involved_in ISO (PMID:12393390), (PMID:19009525) RGD PMID:12393390 PMID:19009525 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718
JBrowse link
G Lpl lipoprotein lipase involved_in ISO RNAcentral:URS00005C83FD_10090 (MGI:6282927|PMID:22963823) RGD PMID:22963823 MGI:6282927 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (MGI:3836337|PMID:19265123) RGD PMID:19265123 MGI:3836337 NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO (MGI:5645195|PMID:24380872) RGD PMID:24380872 MGI:5645195 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (MGI:5532755|PMID:24020373) RGD PMID:24020373 MGI:5532755 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:21957149)
UniProt
RGD
PMID:16127453 PMID:21957149 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir144 microRNA 144 involved_in ISO (PMID:24733347) RGD PMID:24733347 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
JBrowse link
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) RGD PMID:27277332 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir27b microRNA 27b acts_upstream_of ISO (PMID:20164187) RGD PMID:20164187 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISO
IMP
GO_REF:0000107
(MGI:6201889|PMID:25049354)
Ensembl
RGD
PMID:25049354 PMID:25049354 GO_REF:0000107 MGI:6201889, RGD:13792525 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (MGI:2670551|PMID:12872135), (MGI:3042099|PMID:12719478), (MGI:3619313|PMID:11067888), (MGI:3640248|PMID:10607756) RGD PMID:10607756 PMID:11067888 PMID:12719478 PMID:12872135 MGI:2670551 MGI:3042099 MGI:3619313 MGI:3640248 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Ncl nucleolin IMP RGD PMID:21309751 RGD:9686449 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (MGI:3709926|PMID:17242187) RGD PMID:17242187 MGI:3709926 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within IMP
ISO
MGI:2429397|MGI:2674231 (MGI:3775161|PMID:18261938) RGD PMID:18261938 PMID:22450316 MGI:3775161, RGD:9831170 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in
ISO MGI:1341839|MGI:2680581|MGI:3529594 (MGI:3050756|PMID:15220916), (MGI:3775161|PMID:18261938)
(PMID:17187069)
(PMID:21040358)
RGD PMID:15220916 PMID:17187069 PMID:18261938 PMID:21040358 MGI:3050756 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30822544) RGD PMID:30822544 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in ISO
IEA
(PMID:30822544)
GO_REF:0000107
RGD
Ensembl
PMID:30822544 GO_REF:0000107 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA
(PMID:30822544)
GO_REF:0000107
RGD
Ensembl
PMID:30822544 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
JBrowse link
G Orm1 orosomucoid 1 involved_in ISO (PMID:8774350) RGD PMID:8774350 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3709926|PMID:17242187)
Ensembl
RGD
PMID:17242187 GO_REF:0000107 MGI:3709926 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900)
Ensembl
RGD
PMID:19136564 PMID:22041900 GO_REF:0000107 MGI:3844414 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:P05067 (PMID:29061364) RGD PMID:29061364 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:2545780 RGD:10043183 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISO UniProtKB:P97797 (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:Q64455 (MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:3774343 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO UniProtKB:P06800 (MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:3774343 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16982856), (PMID:21487011) RGD PMID:16982856 PMID:21487011 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)
(MGI:5543891|PMID:21887730)
RGD PMID:11894098 PMID:18261938 PMID:21887730 MGI:2176422 MGI:3775161 MGI:5543891 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (MGI:3607020|PMID:16227612) RGD PMID:16227612 MGI:3607020 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519
JBrowse link
G Selenok selenoprotein K involved_in ISO (MGI:4939970|PMID:21220695) RGD PMID:21220695 MGI:4939970 NCBI chr16:5,152,066...5,160,648
Ensembl chr16:5,152,066...5,159,188
JBrowse link
G Setd4 SET domain containing 4 involved_in ISO (MGI:6694359|PMID:31376731) RGD PMID:31376731 MGI:6694359 NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (MGI:1861065|PMID:10899905)
(PMID:10899905)
RGD PMID:10899905 MGI:1861065 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (MGI:2686801|PMID:14691481) RGD PMID:14691481 MGI:2686801 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of
involved_in
ISO RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314) RGD PMID:31886314 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA
(PMID:19358895)
GO_REF:0000107
RGD
Ensembl
PMID:19358895 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18726995) RGD PMID:18726995 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135) RGD PMID:12855817 PMID:12872135 MGI:2669022 MGI:2670551 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:16301656), (PMID:19509286)
PMID:21873635
MGI:3573942 (MGI:3528769|PMID:15690042)
(MGI:3531416|PMID:12447442), (MGI:3713420|PMID:16301656)
RGD PMID:12447442 PMID:15690042 PMID:16301656 PMID:19509286 PMID:21873635 MGI:3528769 MGI:3531416 MGI:3713420, RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr1 toll-like receptor 1 involved_in ISO (MGI:3609367|PMID:12077222) RGD PMID:12077222 MGI:3609367 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within
involved_in
ISO MGI:2178675|MGI:2674036 (MGI:2178646|PMID:10549626), (MGI:3042099|PMID:12719478), (MGI:3528769|PMID:15690042), (MGI:3611539|PMID:16239543), (MGI:3619313|PMID:11067888)
ComplexPortal:CPX-1134|UniProtKB:P05067|UniProtKB:P49768 (MGI:4456948|PMID:15356140), (MGI:5307186|PMID:22198949)
RGD PMID:10549626 PMID:11067888 PMID:12719478 PMID:15356140 PMID:15690042 More... MGI:2178646 MGI:3042099 MGI:3528769 MGI:3611539 MGI:3619313 MGI:4456948 MGI:5307186 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 involved_in
acts_upstream_of_or_within
ISO (MGI:4456948|PMID:15356140)
MGI:2653138 (MGI:3697006|PMID:17008311)
RGD PMID:15356140 PMID:17008311 MGI:3697006 MGI:4456948 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4456948|PMID:15356140)
MGI:1857718|MGI:1860755|MGI:1860885 (MGI:1351361|PMID:10623794), (MGI:2178646|PMID:10549626), (MGI:2686801|PMID:14691481), (MGI:3640248|PMID:10607756), (MGI:3775161|PMID:18261938)
(PMID:17951129), (PMID:30321456)
Ensembl
RGD
PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15356140 More... GO_REF:0000107 MGI:1351361 MGI:2178646 MGI:2686801 MGI:3640248 MGI:3775161 MGI:4456948 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (MGI:3828189|PMID:18931679), (MGI:4456948|PMID:15356140) RGD PMID:15356140 PMID:18931679 MGI:3828189 MGI:4456948 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tmem106a transmembrane protein 106A involved_in ISS
ISO
GO_REF:0000024
(MGI:6216178|PMID:26215746)
UniProt
RGD
PMID:26215746 GO_REF:0000024 MGI:6216178 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IMP RGD PMID:20967881 RGD:5130945 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 involved_in ISO (PMID:16108830) RGD PMID:16108830 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20007935) RGD PMID:20007935 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:5638298|PMID:25690660) RGD PMID:25690660 MGI:5638298 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO ComplexPortal:CPX-1134|UniProtKB:Q9EQD0 (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 involved_in ISO (MGI:5619432|PMID:23776228) RGD PMID:23776228 MGI:5619432 NCBI chr11:57,052,129...57,823,679
Ensembl chr11:57,072,880...57,510,210
JBrowse link
regulation of TRAIL production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase NOT|involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
regulation of tumor necrosis factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4437182|PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3663486 (MGI:3654747|PMID:16862125) RGD PMID:16862125 MGI:3654747 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Cd300ld Cd300 molecule-like family member D acts_upstream_of_or_within ISO (MGI:3721207|PMID:17543387) RGD PMID:17543387 MGI:3721207 NCBI chr10:100,082,950...100,115,853
Ensembl chr10:100,083,490...100,115,821
JBrowse link
G Cd47 Cd47 molecule involved_in ISO (PMID:11509594) RGD PMID:11509594 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO UniProtKB:P05067 (MGI:6162390|PMID:23499256) RGD PMID:23499256 MGI:6162390 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:22184119 RGD:11041001 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (PMID:15014438)
(MGI:1352048|PMID:10559880)
RGD PMID:10559880 PMID:15014438 MGI:1352048 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mir361 microRNA 361 involved_in ISO (PMID:28444107) RGD PMID:28444107 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:4421295 (MGI:5637650|PMID:25084278) RGD PMID:25084278 MGI:5637650 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Sirpa signal-regulatory protein alpha involved_in IMP
ISO
PMID:16055727
UniProtKB:Q08722 (PMID:11509594)
RGD PMID:11509594 PMID:16055727 RGD:13792550 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
G Tbc1d23 TBC1 domain family, member 23 acts_upstream_of_or_within ISO MGI:3857844 (MGI:5314289|PMID:22312129) RGD PMID:22312129 MGI:5314289 NCBI chr11:43,303,355...43,361,507
Ensembl chr11:43,303,355...43,361,503
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:24199847 RGD:12910488 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnfsf18 TNF superfamily member 18 NOT|involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5554502|PMID:24218451) RGD PMID:24218451 MGI:5554502 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 acts_upstream_of_or_within ISO MGI:109298 (MGI:5532755|PMID:24020373) RGD PMID:24020373 MGI:5532755 NCBI chr 5:47,422,513...47,441,476
Ensembl chr 5:47,422,587...47,441,461
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO
GO_REF:0000024
(PMID:15014438)
UniProt
RGD
PMID:15014438 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    multicellular organismal process 8936
      cytokine production 864
        tumor necrosis factor superfamily cytokine production 209
          TRAIL production + 4
          lymphotoxin A production + 1
          negative regulation of tumor necrosis factor superfamily cytokine production + 82
          positive regulation of tumor necrosis factor superfamily cytokine production + 121
          regulation of tumor necrosis factor superfamily cytokine production + 209
          tumor necrosis factor (ligand) superfamily member 11 production + 3
          tumor necrosis factor production + 205
Path 2
Term Annotations click to browse term
  biological_process 20099
    metabolic process 12353
      organic substance metabolic process 11873
        macromolecule metabolic process 10218
          gene expression 6704
            cytokine production 864
              tumor necrosis factor superfamily cytokine production 209
                TRAIL production + 4
                lymphotoxin A production + 1
                negative regulation of tumor necrosis factor superfamily cytokine production + 82
                positive regulation of tumor necrosis factor superfamily cytokine production + 121
                regulation of tumor necrosis factor superfamily cytokine production + 209
                tumor necrosis factor (ligand) superfamily member 11 production + 3
                tumor necrosis factor production + 205
paths to the root