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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transforming growth factor beta production
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Accession:GO:0071635 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms:exact_synonym: negative regulation of TGF-B production;   negative regulation of TGF-beta production;   negative regulation of TGFb production;   negative regulation of TGFbeta production
 narrow_synonym: negative regulation of transforming growth factor-beta secretion
 alt_id: GO:2001202

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negative regulation of transforming growth factor beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbln1 fibulin 1 involved_in ISO (PMID:25834989) RGD PMID:25834989 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468 		JBrowse link
G Fn1 fibronectin 1 involved_in ISO
IEA		 (PMID:25834989)
GO_REF:0000107		 RGD
Ensembl		 PMID:25834989 GO_REF:0000107 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20100461 RGD:4145466 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:3041135 (MGI:5529574|PMID:23994610) RGD PMID:23994610 MGI:5529574 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:29700287 RGD:26884455 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911 		JBrowse link
negative regulation of transforming growth factor beta activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B involved_in ISO RGD DOI:10.1016/j.procbio.2011.10.027 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
ISS		 (PMID:20599762)
GO_REF:0000024		 RGD
UniProt		 PMID:20599762 GO_REF:0000024 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243 		JBrowse link
negative regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724 		JBrowse link
negative regulation of transforming growth factor beta1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd2ap CD2-associated protein acts_upstream_of_or_within ISO MGI:98725 (MGI:5297732|PMID:21911934) RGD PMID:21911934 MGI:5297732 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:15899807)
GO_REF:0000107		 RGD
Ensembl		 PMID:15899807 GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182 		JBrowse link
G Gata6 GATA binding protein 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21127043)		 Ensembl
RGD		 PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
ISS		 (PMID:26126825)
GO_REF:0000024		 RGD
UniProt		 PMID:26126825 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6478057|PMID:25159578)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25159578 GO_REF:0000024 GO_REF:0000107 MGI:6478057 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA		 (MGI:5638298|PMID:25690660)
PMID:21873635		 RGD PMID:25690660, PMID:21873635, PMID:21873635 MGI:5638298, RGD:13792537, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303 		JBrowse link
negative regulation of transforming growth factor beta2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677 		JBrowse link
G Gata6 GATA binding protein 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21127043)		 Ensembl
RGD		 PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
negative regulation of transforming growth factor beta3 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule involved_in ISO
ISS		 (PMID:16930538)
GO_REF:0000024		 RGD
UniProt		 PMID:16930538, PMID:16930538, PMID:16930538 GO_REF:0000024, RGD:8553566, RGD:8553566 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    multicellular organismal process 9081
      cytokine production 770
        transforming growth factor beta production 46
          negative regulation of transforming growth factor beta production 16
            negative regulation of transforming growth factor beta activation + 3
            negative regulation of transforming growth factor beta1 production + 7
            negative regulation of transforming growth factor beta2 production + 2
            negative regulation of transforming growth factor beta3 production + 1
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        negative regulation of biological process 5713
          negative regulation of metabolic process 3271
            negative regulation of macromolecule metabolic process 3004
              negative regulation of gene expression 1130
                negative regulation of cytokine production 288
                  negative regulation of transforming growth factor beta production 16
                    negative regulation of transforming growth factor beta activation + 3
                    negative regulation of transforming growth factor beta1 production + 7
                    negative regulation of transforming growth factor beta2 production + 2
                    negative regulation of transforming growth factor beta3 production + 1
paths to the root