Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of transforming growth factor beta production
go back to main search page
Accession:GO:0071634 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms:exact_synonym: regulation of TGF-B production;   regulation of TGF-beta production;   regulation of TGFb production;   regulation of TGFbeta production
 narrow_synonym: regulation of transforming growth factor-beta secretion
 alt_id: GO:2001201


show annotations for term's descendants           Sort by:
negative regulation of transforming growth factor beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBLN1 fibulin 1 involved_in ISO (PMID:25834989) UniProt PMID:25834989 NCBI chr10:20,498,097...20,564,776
Ensembl chr10:20,498,567...20,627,836 		JBrowse link
G FN1 fibronectin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:22,456,854...22,522,410
Ensembl chr37:22,420,428...22,523,123 		JBrowse link
G IL13 interleukin 13 ISO RGD PMID:20100461 RGD:4145466 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23994610) MGI PMID:23994610 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MIR125A microRNA mir-125a ISO RGD PMID:29700287 RGD:26884455 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
negative regulation of transforming growth factor beta1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21911934) Ensembl
MGI		 PMID:21911934 GO_REF:0000107 NCBI chr12:15,538,215...15,683,619
Ensembl chr12:15,538,356...15,681,011 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423 		JBrowse link
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26126825) UniProt PMID:26126825 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182 		JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan involved_in ISO (MGI:6478057|PMID:25159578) UniProt PMID:25159578 MGI:6478057 NCBI chr21:21,910,333...21,927,758
Ensembl chr21:21,915,956...21,928,119 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
negative regulation of transforming growth factor beta2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
negative regulation of transforming growth factor beta3 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD24 CD24 molecule involved_in ISO (PMID:16930538) UniProt PMID:16930538 NCBI chr12:64,239,957...64,245,114 JBrowse link
positive regulation of transforming growth factor beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD200 CD200 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:16,872,849...16,892,161
Ensembl chr33:16,873,048...16,890,954 		JBrowse link
G FERMT1 FERM domain containing kindlin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,748,632...15,785,025
Ensembl chr24:15,748,629...15,782,880 		JBrowse link
G IFNB1 interferon beta 1 ISO RGD PMID:10494101 RGD:401854240 NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LOC490356 lymphotactin involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chr 7:29,986,433...29,991,096 JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO RGD PMID:15534927 RGD:11532676 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036 		JBrowse link
G THBS1 thrombospondin 1 ISO RGD PMID:17640965 RGD:2317942 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
positive regulation of transforming growth factor beta1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18097059) Ensembl
MGI		 PMID:18097059 GO_REF:0000107 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G LUM lumican involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:31,792,872...31,800,444
Ensembl chr15:31,793,233...31,800,912 		JBrowse link
G SERPINB7 serpin family B member 7 ISO RGD PMID:21945418 RGD:7207383 NCBI chr 1:13,336,067...13,392,674
Ensembl chr 1:13,336,837...13,358,125 		JBrowse link
positive regulation of transforming growth factor beta2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17767158) Ensembl
MGI		 PMID:17767158 GO_REF:0000107 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2175930|PMID:11854453) BHF-UCL
Ensembl		 PMID:11854453 GO_REF:0000107 MGI:2175930 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G WNT11 Wnt family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17767158) Ensembl
MGI		 PMID:17767158 GO_REF:0000107 NCBI chr21:22,442,496...22,463,040
Ensembl chr21:22,446,051...22,463,173 		JBrowse link
positive regulation of transforming growth factor beta3 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 PMID:21308733 RGD:10059386 RGD:1625706 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:16891311 RGD:1625706 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
regulation of transforming growth factor beta2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    multicellular organismal process 8083
      regulation of multicellular organismal process 3298
        regulation of cytokine production 891
          regulation of transforming growth factor beta production 35
            negative regulation of transforming growth factor beta production + 12
            positive regulation of transforming growth factor beta production + 20
            regulation of transforming growth factor beta1 production + 11
            regulation of transforming growth factor beta2 production + 8
            regulation of transforming growth factor beta3 production + 3
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of cellular process 11571
          regulation of cellular metabolic process 5784
            regulation of cellular biosynthetic process 5175
              regulation of macromolecule biosynthetic process 5079
                regulation of gene expression 4962
                  regulation of cytokine production 891
                    regulation of transforming growth factor beta production 35
                      negative regulation of transforming growth factor beta production + 12
                      positive regulation of transforming growth factor beta production + 20
                      regulation of transforming growth factor beta1 production + 11
                      regulation of transforming growth factor beta2 production + 8
                      regulation of transforming growth factor beta3 production + 3
paths to the root