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ONTOLOGY REPORT - ANNOTATIONS

Term:cytoplasm protein quality control by the ubiquitin-proteasome system
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Accession:GO:0071629 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.
Comment:See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
Synonyms:exact_synonym: cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown;   cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism;   cytoplasm-associated proteasomal ubiquitin-dependent protein degradation;   ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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cytoplasm protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF126 ring finger protein 126 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,673,302...77,683,312
Ensembl chr 2:77,673,353...77,683,311 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    response to stimulus 10058
      cellular response to stimulus 8623
        cellular response to stress 1945
          cellular response to topologically incorrect protein 99
            cellular response to misfolded protein 16
              cytoplasm protein quality control by the ubiquitin-proteasome system 1
Path 2
Term Annotations click to browse term
  biological_process 17813
    metabolic process 10347
      organic substance metabolic process 9911
        organic substance catabolic process 2145
          organonitrogen compound catabolic process 1394
            protein catabolic process 1002
              proteolysis involved in protein catabolic process 758
                modification-dependent protein catabolic process 609
                  ubiquitin-dependent protein catabolic process 596
                    proteasome-mediated ubiquitin-dependent protein catabolic process 396
                      cytoplasm protein quality control by the ubiquitin-proteasome system 1
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