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ONTOLOGY REPORT - ANNOTATIONS


Term:phosphorylation of RNA polymerase II C-terminal domain serine 5 residues
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Accession:GO:0071620 term browser browse the term
Definition:The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).


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  biological_process 19599
    metabolic process 11860
      cellular metabolic process 10814
        phosphorus metabolic process 2862
          phosphate-containing compound metabolic process 2840
            phosphorylation 1968
              protein phosphorylation 1626
                phosphorylation of RNA polymerase II C-terminal domain 13
                  phosphorylation of RNA polymerase II C-terminal domain serine 5 residues 0
                    phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter 0
                    phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex 0
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Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      cellular metabolic process 10814
        cellular aromatic compound metabolic process 5630
          nucleobase-containing compound metabolic process 5413
            nucleic acid metabolic process 4923
              RNA metabolic process 4406
                RNA biosynthetic process 3420
                  nucleic acid-templated transcription 3405
                    transcription, DNA-templated 3403
                      regulation of transcription, DNA-templated 3272
                        regulation of transcription by RNA polymerase II 2387
                          phosphorylation of RNA polymerase II C-terminal domain 13
                            phosphorylation of RNA polymerase II C-terminal domain serine 5 residues 0
                              phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter 0
                              phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex 0
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