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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to transforming growth factor beta stimulus
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Accession:GO:0071560 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
Synonyms:exact_synonym: cellular response to TGF-beta stimulus;   cellular response to TGFbeta stimulus



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cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:15629889 RGD:8693572 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711
JBrowse link
G ACTR3 actin related protein 3 ISO RGD PMID:22319661 RGD:11530045 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186
JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:17,267,483...17,284,155
Ensembl chr 5:17,263,907...17,286,276
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 ISO RGD PMID:2401226 RGD:10053613 NCBI chr10:65,650,223...65,679,878
Ensembl chr10:65,576,464...65,678,248
JBrowse link
G ANKRD1 ankyrin repeat domain 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:102,603,777...102,612,857
Ensembl chr14:102,603,777...102,612,839
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:11003619 RGD:2325753 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
JBrowse link
G ARG1 arginase 1 ISO RGD PMID:12069499 RGD:634666 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,038...32,028,986
JBrowse link
G CAV1 caveolin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5289760|PMID:21829547) Ensembl
Ensembl
MGI
PMID:21829547 GO_REF:0000107 MGI:5289760 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO RGD PMID:20429874 RGD:4889909 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:11369440 RGD:11252200 NCBI chr 1:200,666,250...200,770,880
Ensembl chr 1:200,761,004...200,766,056
JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:163,236,864...163,271,222
Ensembl chr 1:163,237,100...163,271,164
JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:18031476 RGD:11344898 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,767...127,730,657
JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:28,219,241...28,229,113
Ensembl chr13:28,176,793...28,229,096
JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in ISO PMID:19362560 RGD
UniProt
PMID:19362560 PMID:23560091 RGD:8552683 RGD:8554531 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,003
JBrowse link
G COL4A2 collagen type IV alpha 2 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17525254) Ensembl
Ensembl
UniProt
PMID:17525254 GO_REF:0000107 NCBI chr11:76,996,885...77,161,617
Ensembl chr11:76,997,516...77,161,615
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:21308733 RGD:10059386 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,697,408...110,771,755
JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO RGD PMID:12837295 RGD:11568682 NCBI chr12:47,656,805...47,685,641 JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:50,528,950...50,558,664
Ensembl chr14:50,528,954...50,558,663
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:12446007 RGD:4892023 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:21762377 RGD:7243156 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,514,722...24,776,903
JBrowse link
G DBN1 drebrin 1 ISO RGD PMID:22319661 RGD:11530045 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,496,873
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:16087782 RGD:150429767 NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,375
JBrowse link
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:78,186,667...78,191,788
Ensembl chr15:78,185,790...78,191,297
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:24211420 RGD:9588224 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,564...69,029,919
JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:8439651 RGD:8662306 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
G ELN elastin ISO RGD PMID:9224206 RGD:9585659 NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,073...11,244,897
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:24157151 RGD:13204713 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821807|PMID:18794329) Ensembl
Ensembl
MGI
PMID:18794329 GO_REF:0000107 MGI:3821807 NCBI chr15:31,159,214...31,295,891
Ensembl chr15:31,159,217...31,295,896
JBrowse link
G FBN1 fibrillin 1 ISO RGD PMID:11012893 RGD:7387263 NCBI chr 1:123,102,011...123,359,649
Ensembl chr 1:123,102,009...123,359,649
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD PMID:12648559 RGD:12801436 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,710...131,579,703
JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:16669970 RGD:1626090 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5289760|PMID:21829547) Ensembl
Ensembl
MGI
PMID:21829547 GO_REF:0000107 MGI:5289760 NCBI chr 1:77,584,675...77,810,605
Ensembl chr 1:77,585,439...77,810,581
JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:19553350 RGD:9590229 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr13:32,805,220...32,813,684
Ensembl chr13:32,805,223...32,815,335
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:16628634 RGD:9686088 NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,315,964...35,317,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:12837295 RGD:11568682 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,925...137,690,666
JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:16686695 RGD:6483452 NCBI chr  X:124,595,649...124,618,292
Ensembl chr  X:124,595,651...124,618,307
JBrowse link
G LIMS1 LIM zinc finger domain containing 1 involved_in ISO (PMID:21390327) UniProt PMID:21390327 NCBI chr 3:47,607,737...47,704,921 JBrowse link
G MAPK7 mitogen-activated protein kinase 7 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,128,686...60,149,270
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:96,122,407...96,296,927
Ensembl chr 2:96,122,407...96,296,842
JBrowse link
G MIR125A microRNA mir-125a ISO RGD PMID:29700287 RGD:26884455 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
JBrowse link
G MIR155 microRNA mir-155 acts_upstream_of_or_within ISO (MGI:5556350|PMID:24391219) MGI PMID:24391219 MGI:5556350 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MIR192 microRNA mir-192 acts_upstream_of_or_within ISO (MGI:4941448|PMID:20393144) MGI PMID:20393144 MGI:4941448 NCBI chr 2:7,285,667...7,285,746
Ensembl chr 2:7,285,667...7,285,746
JBrowse link
G MIR21 microRNA mir-21 acts_upstream_of_or_within ISO (MGI:5556350|PMID:24391219) MGI PMID:24391219 MGI:5556350 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MUC4 mucin 4, cell surface associated ISO RGD PMID:9857062 RGD:2324952 NCBI chr13:134,192,412...134,248,435 JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:21792926 RGD:8662393 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:18845355 RGD:2324663 NCBI chr 9:22,622,105...22,776,691
Ensembl chr 9:22,624,195...22,776,554
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,937...144,956,095
JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:26,417,793...26,451,707
Ensembl chr17:26,417,795...26,451,928
JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 ISO RGD PMID:15629889 RGD:8693572 NCBI chr13:133,276,122...133,383,506
Ensembl chr13:133,283,300...133,496,071
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:22073128 RGD:8554355 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,159...14,241,197
JBrowse link
G PDCD5 programmed cell death 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:42,483,653...42,491,589
Ensembl chr 6:42,482,931...42,491,591
JBrowse link
G PDE2A phosphodiesterase 2A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:7,136,637...7,227,966
Ensembl chr 9:7,136,644...7,227,964
JBrowse link
G PDE3A phosphodiesterase 3A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:52,413,503...52,737,771
Ensembl chr 5:52,413,105...52,738,829
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:16039137 RGD:1581755 NCBI chr 3:296,399...322,967
Ensembl chr 3:303,311...323,036
JBrowse link
G PDGFD platelet derived growth factor D ISO RGD PMID:23585135 RGD:9854632 NCBI chr 9:34,388,636...34,621,227
Ensembl chr 9:34,388,636...34,621,244
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO RGD PMID:15862831 RGD:9999173 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:18466611 RGD:2311658 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,582,481...14,723,336
JBrowse link
G PENK proenkephalin ISO RGD PMID:8584038 RGD:10003035 NCBI chr 4:75,525,497...75,530,403
Ensembl chr 4:75,525,555...75,561,444
JBrowse link
G POSTN periostin ISO RGD PMID:22886209 RGD:10040993 NCBI chr11:13,225,183...13,258,973
Ensembl chr11:13,182,272...13,259,019
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO with follicle-stimulating hormone RGD PMID:18511507 RGD:4781450 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,961,909
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5289760|PMID:21829547) Ensembl
Ensembl
MGI
PMID:21829547 GO_REF:0000107 MGI:5289760 NCBI chr 1:189,248,974...189,296,147
Ensembl chr 1:189,170,585...189,291,350
JBrowse link
G PTK2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO (MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:5289760 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,613...2,896,060
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:23845590 RGD:9835377 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,289...78,134,103
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in IGI (PMID:26634652) BHF-UCL
BHF-UCL
PMID:26634652 NCBI chr 6:106,163,899...106,314,998
Ensembl chr 6:106,163,903...106,314,944
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in IGI (PMID:26634652) BHF-UCL
BHF-UCL
PMID:26634652 NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,353,119...125,491,963
JBrowse link
G RUNX1 RUNX family transcription factor 1 acts_upstream_of_or_within ISO (MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:5532214 NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,835...198,638,189
JBrowse link
G SCX scleraxis bHLH transcription factor acts_upstream_of_or_within ISO (PMID:18498113), (PMID:9328840) UniProt PMID:9328840 PMID:18498113 NCBI chr 4:500,884...503,276
Ensembl chr 4:501,172...502,994
JBrowse link
G SERPINE1 serpin family E member 1 acts_upstream_of_or_within ISO (MGI:5289760|PMID:21829547) RGD
MGI
PMID:19247458 PMID:21829547 MGI:5289760 RGD:8547745 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748
JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,083...165,124,454
JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,510,229...98,542,382
JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 ISO RGD PMID:10022522 RGD:10448942 NCBI chr 6:54,288,354...54,304,272
Ensembl chr 6:54,288,354...54,304,270
JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,160,723...50,161,570
JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) UniProt PMID:21401405 NCBI chr 2:42,447,391...43,068,824
Ensembl chr 2:42,448,216...43,068,325
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISS
ISO
(PMID:17525254) Ensembl
Ensembl
UniProt
UniProt
UniProt
PMID:17525254 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5289760|PMID:21829547) MGI
Ensembl
PMID:21829547 GO_REF:0000107 MGI:5289760 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
JBrowse link
G STAR steroidogenic acute regulatory protein ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,347,864...48,385,464
JBrowse link
G STK16 serine/threonine kinase 16 ISO RGD PMID:10947953 RGD:727297 NCBI chr15:121,285,065...121,288,475
Ensembl chr15:121,275,048...121,288,472
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:5532214|PMID:23861879) AgBase
AgBase
Ensembl
MGI
PMID:23861879 GO_REF:0000024 GO_REF:0000107 MGI:5532214 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,859,270...240,918,528
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked acts_upstream_of_or_within ISO (MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:5532214 NCBI chr  X:36,736,049...36,888,702
Ensembl chr  X:36,760,819...36,885,275
JBrowse link
G WNT10A Wnt family member 10A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:120,925,204...120,939,032
Ensembl chr15:120,925,201...120,938,430
JBrowse link
G WNT2 Wnt family member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,277...29,028,107
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:15040835) UniProt PMID:15040835 NCBI chr 6:80,110,238...80,138,165 JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207
JBrowse link
G WNT7A Wnt family member 7A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:70,538,802...70,602,464
Ensembl chr13:70,538,894...70,602,455
JBrowse link
G WWOX WW domain containing oxidoreductase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,911,139...9,871,102
JBrowse link
G XCL1 chemokine (C motif) ligand 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,198...82,436,180
JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:5289760 NCBI chr 6:105,505,944...105,600,694
Ensembl chr 6:105,505,479...105,600,687
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 ISO RGD PMID:16824956 RGD:2325877 NCBI chr10:42,013,114...42,216,139
Ensembl chr10:42,013,045...42,214,205
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:92,490,069...92,495,864
Ensembl chr 7:92,490,011...92,495,574
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,406...97,204,700
JBrowse link
negative regulation of cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:18314484 RGD:11341711 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,615...104,844,921
JBrowse link
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:78,186,667...78,191,788
Ensembl chr15:78,185,790...78,191,297
JBrowse link
G IL4 interleukin 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28467929) ARUK-UCL PMID:28467929 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G ADAMTSL2 ADAMTS like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5638958|PMID:25762570) Ensembl
Ensembl
MGI
PMID:25762570 GO_REF:0000107 MGI:5638958 NCBI chr 1:273,119,826...273,155,412
Ensembl chr 1:273,119,000...273,155,412
JBrowse link
G ASPN asporin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:42,165,553...42,192,902
Ensembl chr 3:42,165,553...42,192,813
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA Ensembl
InterPro
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,354...40,060,323
JBrowse link
G BCL9L BCL9 like involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 9:46,146,519...46,175,052
Ensembl chr 9:46,146,514...46,174,589
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:28467929) Ensembl
Ensembl
ARUK-UCL
PMID:28467929 GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,215
JBrowse link
G CAV1 caveolin 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CAV2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5298182|PMID:21832243) Ensembl
Ensembl
MGI
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr18:29,699,012...29,707,277
Ensembl chr18:29,699,020...29,707,277
JBrowse link
G CD109 CD109 molecule involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:92,081,675...92,241,079
Ensembl chr 1:92,048,461...92,286,747
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3767479|PMID:16079159) Ensembl
Ensembl
MGI
PMID:16079159 GO_REF:0000107 MGI:3767479 NCBI chr 5:79,788,558...80,068,903
Ensembl chr 5:79,787,995...80,067,816
JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:3768618 NCBI chr 6:97,253,074...97,268,355 JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (MGI:3055566|PMID:14721776) MGI PMID:14721776 MGI:3055566 NCBI chr 2:66,068,722...66,073,537 JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:112,031,910...112,039,928
Ensembl chr 3:112,031,919...112,046,437
JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 2:6,680,832...6,682,506
Ensembl chr 2:6,680,835...6,684,494
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) FlyBase PMID:11583628 NCBI chr17:33,910,047...33,935,212 JBrowse link
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4829577|PMID:20530870) Ensembl
Ensembl
MGI
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr 6:13,011,829...13,165,487
Ensembl chr 6:13,011,860...13,165,452
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3771280|PMID:17991893) Ensembl
Ensembl
MGI
PMID:17991893 GO_REF:0000107 MGI:3771280 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3034116|PMID:14973287) Ensembl
Ensembl
MGI
PMID:14973287 GO_REF:0000107 MGI:3034116 NCBI chr14:132,043,044...132,103,590
Ensembl chr14:132,043,006...132,103,595
JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:2,794,780...2,819,686
Ensembl chr 8:2,793,797...2,820,185
JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:38,935,631...39,006,721
Ensembl chr13:38,939,279...39,006,690
JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
InterPro
GO_Central
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:96,401,650...96,578,162
Ensembl chr 6:96,401,650...96,577,643
JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:29,596,334...29,672,704
Ensembl chr 5:29,596,334...29,673,875
JBrowse link
G LOC100520248 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:48,182,580...48,185,328
Ensembl chr 6:48,184,566...48,185,203
JBrowse link
G LOC100520342 nephrocan-like involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:44,204,855...44,230,097 JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G MECOM MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) UniProt PMID:15897867 NCBI chr13:107,753,207...108,336,136
Ensembl chr13:107,754,480...108,335,503
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in ISO (PMID:19293183) UniProt PMID:19293183 NCBI chr 7:63,487,200...63,491,580
Ensembl chr 7:63,487,807...63,491,575
JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3588024|PMID:16103213) Ensembl
Ensembl
MGI
PMID:16103213 GO_REF:0000107 MGI:3588024 NCBI chr 1:118,913,400...118,958,140
Ensembl chr 1:118,913,785...118,954,614
JBrowse link
G ONECUT2 one cut homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3588024|PMID:16103213) Ensembl
Ensembl
MGI
PMID:16103213 GO_REF:0000107 MGI:3588024 NCBI chr 1:106,751,346...106,812,484
Ensembl chr 1:106,751,173...106,799,607
JBrowse link
G PBLD phenazine biosynthesis like protein domain containing involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:71,442,850...71,487,542
Ensembl chr14:71,440,778...71,487,480
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,429,931...39,532,583
JBrowse link
G PEG10 paternally expressed 10 involved_in ISO (PMID:15611116) HGNC-UCL PMID:15611116 NCBI chr 9:74,474,121...74,486,983
Ensembl chr 9:74,474,058...74,486,980
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:68,715,898...68,729,471
Ensembl chr 2:68,715,880...68,729,469
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
Ensembl
GO_Central
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr17:57,999,287...58,054,329
Ensembl chr17:57,999,287...58,054,118
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31611175) ARUK-UCL
Ensembl
Ensembl
PMID:31611175 GO_REF:0000107 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within
involved_in
ISO (PMID:28467929)
(PMID:31023188)
ARUK-UCL
BHF-UCL
PMID:28467929 PMID:31023188 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:189,248,974...189,296,147
Ensembl chr 1:189,170,585...189,291,350
JBrowse link
G PRDM16 PR/SET domain 16 involved_in
acts_upstream_of_or_within
NOT|involved_in
IEA
ISO
(MGI:4430027|PMID:20007998)
(PMID:14656887)
Ensembl
Ensembl
MGI
UniProt
PMID:14656887 PMID:20007998 GO_REF:0000107 MGI:4430027 NCBI chr 6:64,704,181...65,012,580
Ensembl chr 6:64,704,468...65,012,575
JBrowse link
G RASL11B RAS like family 11 member B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3505646|PMID:15239668) Ensembl
Ensembl
MGI
PMID:15239668 GO_REF:0000107 MGI:3505646 NCBI chr 8:39,703,399...39,708,174
Ensembl chr 8:39,702,613...39,708,167
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G SKI SKI proto-oncogene involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(PMID:15312649)
(MGI:5300220|PMID:21937600)
GO_Central
GO_Central
Ensembl
MGI
PMID:15312649 PMID:21873635 PMID:21937600 GO_REF:0000107 MGI:5300220 NCBI chr 6:64,188,265...64,242,596
Ensembl chr 6:64,188,029...64,241,556
JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3530729|PMID:15677329)
GO_Central
Ensembl
GO_Central
InterPro
MGI
PMID:15677329 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:3530729 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,176
JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
IEA
ISO
(MGI:5300220|PMID:21937600) InterPro
InterPro
MGI
PMID:21937600 GO_REF:0000002 MGI:5300220 NCBI chr 1:96,795,362...96,842,360
Ensembl chr 1:96,795,507...96,842,064
JBrowse link
G SLC2A10 solute carrier family 2 member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16550171), (PMID:26376865) Ensembl
Ensembl
ARUK-UCL
PMID:16550171 PMID:26376865 GO_REF:0000107 NCBI chr17:48,824,054...48,842,811
Ensembl chr17:48,824,414...48,843,201
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:164,652,602...164,735,084
Ensembl chr 1:164,657,086...164,735,083
JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,510,229...98,542,382
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:6,037,732...6,142,569
Ensembl chr 3:6,037,737...6,142,576
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:14,368,683...14,492,129
Ensembl chr12:14,368,256...14,489,017
JBrowse link
G SNX1 sorting nexin 1 acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:3505646 NCBI chr 1:107,903,954...107,949,920 JBrowse link
G SNX25 sorting nexin 25 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr15:46,306,967...46,388,404
Ensembl chr15:46,266,762...46,388,324
JBrowse link
G SNX6 sorting nexin 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:65,156,476...65,205,249
Ensembl chr 7:65,156,472...65,205,241
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:132,903,103...133,016,725
Ensembl chr 1:132,902,304...133,016,467
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 3:76,527,646...76,649,652
Ensembl chr 3:76,523,589...76,649,650
JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 6:47,302,211...47,312,034
Ensembl chr 6:47,302,055...47,309,180
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:100,449,476...100,863,780
Ensembl chr 8:100,450,247...100,863,446
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:52,153,695...52,158,766
Ensembl chr11:52,153,704...52,160,497
JBrowse link
G STRAP serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1321347|PMID:9856985) Ensembl
Ensembl
MGI
PMID:9856985 GO_REF:0000107 MGI:1321347 NCBI chr 5:56,717,196...56,736,889
Ensembl chr 5:56,717,200...56,736,862
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:41,092,514...41,095,181
Ensembl chr 3:41,092,447...41,095,136
JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO (MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:3771280 NCBI chr13:29,537,874...29,544,686
Ensembl chr13:29,540,314...29,543,893
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:17,093,275...17,099,204
Ensembl chr 3:17,090,071...17,099,020
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chr 7:99,133,873...99,162,239
Ensembl chr 7:99,133,511...99,162,232
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,101,190...125,316,796
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3528807|PMID:15657445) Ensembl
Ensembl
MGI
PMID:15657445 GO_REF:0000107 MGI:3528807 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G VASN vasorin involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 3:37,961,425...37,972,477
Ensembl chr 3:37,961,425...37,972,115
JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:96,986,322...97,366,206
Ensembl chr13:97,075,270...97,366,195
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 3:41,136,200...41,139,986
Ensembl chr 3:41,136,200...41,138,785
JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:27,093,241...27,100,423
Ensembl chr12:27,093,679...27,100,423
JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3628833|PMID:16601693) Ensembl
Ensembl
MGI
PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr 5:15,010,607...15,015,007
Ensembl chr 5:15,010,985...15,014,079
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:74,678,293...74,699,347
Ensembl chr 2:74,681,192...74,695,975
JBrowse link
G ZNF451 zinc finger protein 451 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:28,682,284...28,765,489
Ensembl chr 7:28,680,549...28,765,484
JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3829110|PMID:18625725) BHF-UCL PMID:18625725 MGI:3829110 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628833|PMID:16601693) MGI
Ensembl
Ensembl
PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997
JBrowse link
G C17H20orf27 chromosome 17 C20orf27 homolog involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:31,943,018...31,956,754
Ensembl chr17:31,931,675...31,956,750
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:2,019,391...2,022,092
Ensembl chr 2:2,019,490...2,021,853
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:200,666,250...200,770,880
Ensembl chr 1:200,761,004...200,766,056
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:25,155,652...25,158,517
Ensembl chr 1:25,155,664...25,160,279
JBrowse link
G COPS3 COP9 signalosome subunit 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr12:61,000,562...61,023,920
Ensembl chr12:60,994,310...61,045,396
JBrowse link
G CREBBP CREB binding protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,230
JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,514,722...24,776,903
JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G FERMT1 FERM domain containing kindlin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:15,080,585...15,137,947
Ensembl chr17:15,080,587...15,137,753
JBrowse link
G FLCN folliculin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5050037|PMID:21258407) MGI
Ensembl
Ensembl
PMID:21258407 GO_REF:0000107 MGI:5050037 NCBI chr12:61,029,186...61,045,400
Ensembl chr12:61,001,321...61,045,396
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chr 7:53,455,634...53,472,791
Ensembl chr 7:53,460,017...53,472,790
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:64,780,447...64,794,922
Ensembl chr 2:64,780,442...64,798,783
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:9,940,535...10,141,815
Ensembl chr18:9,747,737...10,135,083
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,254,002
JBrowse link
G ING2 inhibitor of growth family member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:44,917,595...44,925,900
Ensembl chr15:44,918,066...44,925,867
JBrowse link
G ITGA8 integrin subunit alpha 8 acts_upstream_of_or_within ISO (MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:3714574 NCBI chr10:46,132,887...46,303,659
Ensembl chr10:46,132,914...46,303,365
JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 acts_upstream_of_or_within ISO (MGI:5543310|PMID:23868260) MGI PMID:23868260 MGI:5543310 NCBI chr 2:74,300,598...74,303,117
Ensembl chr 2:74,300,619...74,315,125
JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:7,358,130...7,364,952
Ensembl chr 2:7,357,951...7,365,128
JBrowse link
G MYOCD myocardin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,538
JBrowse link
G NPNT nephronectin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3714574|PMID:17537792) Ensembl
Ensembl
MGI
PMID:17537792 GO_REF:0000107 MGI:3714574 NCBI chr 8:115,768,963...115,861,170
Ensembl chr 8:115,779,839...115,861,463
JBrowse link
G RNF111 ring finger protein 111 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:3628833|PMID:16601693)
Ensembl
GO_Central
Ensembl
MGI
GO_Central
PMID:16601693 PMID:21873635 GO_REF:0000107 MGI:3628833 NCBI chr 1:112,961,466...113,059,606
Ensembl chr 1:112,961,412...113,059,543
JBrowse link
G SDCBP syndecan binding protein involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 4:74,295,941...74,357,720
Ensembl chr 4:74,295,922...74,341,085
JBrowse link
G SLC2A10 solute carrier family 2 member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26376865) Ensembl
Ensembl
ARUK-UCL
PMID:26376865 GO_REF:0000107 NCBI chr17:48,824,054...48,842,811
Ensembl chr17:48,824,414...48,843,201
JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029
JBrowse link
G SNW1 SNW domain containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:100,718,298...100,749,414
Ensembl chr 7:100,718,036...100,749,356
JBrowse link
G STK11 serine/threonine kinase 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:17,093,275...17,099,204
Ensembl chr 3:17,090,071...17,099,020
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:5617089|PMID:25382630) RGD
MGI
PMID:8106553 PMID:25382630 MGI:5617089 RGD:1579949 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,101,190...125,316,796
JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,781...131,746,115
JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:7,498,879...7,631,347
Ensembl chr15:7,499,026...7,632,655
JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator NOT|involved_in ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr 4:99,970,388...100,058,291
Ensembl chr 4:99,970,395...100,058,188
JBrowse link
G CAV3 caveolin 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4946902|PMID:21182936) Ensembl
Ensembl
MGI
PMID:21182936 GO_REF:0000107 MGI:4946902 NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,776...65,134,066
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (MGI:1335654|PMID:10208746) MGI PMID:10208746 MGI:1335654 NCBI chr 2:66,068,722...66,073,537 JBrowse link
G ENG endoglin involved_in IBA
IEA
ISO
(PMID:21873635) GO_Central
GO_Central
Ensembl
RGD
Ensembl
PMID:17376778 PMID:21873635 GO_REF:0000107 RGD:2313627 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,306,120...268,343,827
JBrowse link
G FOLR1 folate receptor alpha involved_in ISO (MGI:5644149|PMID:21649587) BHF-UCL PMID:21649587 MGI:5644149 NCBI chr 9:6,753,513...6,760,433
Ensembl chr 9:6,746,007...6,760,433
JBrowse link
G GDF2 growth differentiation factor 2 NOT|involved_in ISO (MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:4830635 NCBI chr14:88,506,083...88,513,416
Ensembl chr14:88,507,397...88,513,376
JBrowse link
G IL17F interleukin 17F involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:46,058,371...46,066,039
Ensembl chr 7:46,058,326...46,066,120
JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:26,234,769...26,269,327
Ensembl chr12:26,234,753...26,271,561
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:16,274,955...16,320,980
Ensembl chr 1:16,274,970...16,320,619
JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (MGI:4939579|PMID:21145499) UniProt PMID:21145499 MGI:4939579 NCBI chr11:1,225,523...1,265,970
Ensembl chr11:1,225,527...1,265,946
JBrowse link
G LOC100520248 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:48,182,580...48,185,328
Ensembl chr 6:48,184,566...48,185,203
JBrowse link
G LOX lysyl oxidase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5634219|PMID:25715398) Ensembl
Ensembl
MGI
PMID:25715398 GO_REF:0000107 MGI:5634219 NCBI chr 2:125,595,115...125,607,026
Ensembl chr 2:125,593,116...125,607,594
JBrowse link
G NREP neuronal regeneration related protein involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3034115|PMID:14985127)
GO_Central
GO_Central
MGI
PMID:14985127 PMID:21873635 MGI:3034115 NCBI chr 2:117,505,851...117,867,805
Ensembl chr 2:117,838,657...117,908,590
JBrowse link
G PALS1 protein associated with LIN7 1, MAGUK p55 family member involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:90,955,524...91,055,923
Ensembl chr 7:90,955,680...91,055,620
JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,358
JBrowse link
G SMAD3 SMAD family member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2153314|PMID:11711431) Ensembl
Ensembl
MGI
PMID:11711431 GO_REF:0000107 MGI:2153314 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,083...165,124,454
JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029
JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:11959632 RGD:625758 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,510,229...98,542,382
JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:129,797,438...129,800,568
Ensembl chr 3:129,798,704...129,800,329
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,101,190...125,316,796
JBrowse link
G TGFBR3L transforming growth factor beta receptor 3 like involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 2:71,294,960...71,298,172
Ensembl chr 2:71,294,968...71,297,927
JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:106,058,197...106,195,145
Ensembl chr 4:106,058,191...106,191,802
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3641341|PMID:16824956) Ensembl
Ensembl
MGI
PMID:16824956 GO_REF:0000107 MGI:3641341 NCBI chr10:42,013,114...42,216,139
Ensembl chr10:42,013,045...42,214,205
JBrowse link
G ZNF703 zinc finger protein 703 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:48,692,316...48,696,639
Ensembl chr15:48,692,318...48,696,644
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:123,102,011...123,359,649
Ensembl chr 1:123,102,009...123,359,649
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:131,150,665...131,370,241
Ensembl chr 2:131,152,127...131,370,466
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:106,300,748...106,724,538
Ensembl chr 3:106,300,750...106,724,934
JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:133,470,641...133,496,218
Ensembl chr13:133,470,643...133,496,264
JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C ISO TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr15:64,452,632...64,529,329
Ensembl chr15:64,455,989...64,529,107
JBrowse link
G LOC100520248 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:48,182,580...48,185,328
Ensembl chr 6:48,184,566...48,185,203
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:8106553 RGD:1579949 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,101,190...125,316,796
JBrowse link
transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1935017|PMID:11376112)
GO_Central
GO_Central
Ensembl
MGI
PMID:11376112 PMID:21873635 GO_REF:0000107 MGI:1935017 NCBI chr15:64,749,478...64,891,653
Ensembl chr15:64,748,761...64,892,153
JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2679137|PMID:14580334) Ensembl
Ensembl
MGI
PMID:14580334 GO_REF:0000107 MGI:2679137 NCBI chr 5:17,267,483...17,284,155
Ensembl chr 5:17,263,907...17,286,276
JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr15:47,523,768...47,601,722
Ensembl chr15:47,523,211...47,601,710
JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 acts_upstream_of_or_within ISO PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chr 5:18,642,212...18,648,859
Ensembl chr 5:18,642,823...18,648,848
JBrowse link
G APOA1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) UniProt PMID:23726972 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:39,089,157...39,124,969
Ensembl chr13:39,089,045...39,129,781
JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:79,356,046...79,412,235
Ensembl chr 5:79,356,047...79,412,233
JBrowse link
G ARRB2 arrestin beta 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,776...52,170,344
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IBA
ISO
(PMID:21873635) GO_Central
GO_Central
RGD
PMID:12933693 PMID:21873635 RGD:632261 NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,354...40,060,323
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO RGD PMID:14505427 RGD:1582324 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CDH5 cadherin 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:27,108,560...27,142,145
Ensembl chr 6:27,108,609...27,142,180
JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:58,179,084...58,184,778
Ensembl chr  X:58,179,087...58,184,499
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3690196|PMID:16619037) Ensembl
Ensembl
MGI
PMID:16619037 GO_REF:0000107 MGI:3690196 NCBI chr 1:25,155,652...25,158,517
Ensembl chr 1:25,155,664...25,160,279
JBrowse link
G CLDN5 claudin 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:51,161,490...51,162,382
Ensembl chr14:51,161,032...51,163,482
JBrowse link
G COL1A2 collagen type I alpha 2 chain involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:74,174,484...74,210,407
Ensembl chr 9:74,173,931...74,210,398
JBrowse link
G COL3A1 collagen type III alpha 1 chain involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:93,556,914...93,595,678
Ensembl chr15:93,556,912...93,615,815
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,697,408...110,771,755
JBrowse link
G DUSP22 dual specificity phosphatase 22 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2387732|PMID:12138158)
GO_Central
GO_Central
MGI
PMID:12138158 PMID:21873635 MGI:2387732 NCBI chr 7:43,437...96,270
Ensembl chr 7:43,486...96,270
JBrowse link
G ENG endoglin involved_in
NOT|involved_in
IDA
IBA
IEA
ISO
(PMID:8294451)
(PMID:21873635)
(PMID:18223685)
BHF-UCL
GO_Central
Ensembl
BHF-UCL
BHF-UCL
GO_Central
Ensembl
PMID:8294451 PMID:18223685 PMID:21873635 GO_REF:0000107 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,306,120...268,343,827
JBrowse link
G FERMT2 FERM domain containing kindlin 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:182,519,681...182,606,890
Ensembl chr 1:182,519,681...182,606,869
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
JBrowse link
G FOXH1 forkhead box H1 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 4:320,610...324,570
Ensembl chr 4:320,537...324,481
JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G FUT8 fucosyltransferase 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3608245|PMID:16236725) Ensembl
Ensembl
MGI
PMID:16236725 GO_REF:0000107 MGI:3608245 NCBI chr 7:89,395,637...89,680,502
Ensembl chr 7:89,211,549...89,692,888
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3696537|PMID:17159989) Ensembl
Ensembl
MGI
PMID:17159989 GO_REF:0000107 MGI:3696537 NCBI chr18:9,940,535...10,141,815
Ensembl chr18:9,747,737...10,135,083
JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr14:15,718,261...15,773,534
Ensembl chr14:15,718,266...15,763,710
JBrowse link
G ITGB1 integrin subunit beta 1 NOT|involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)
UniProt PMID:24036928 MGI:5582864 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,398...56,173,795
JBrowse link
G ITGB5 integrin subunit beta 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:135,468,111...135,587,483
Ensembl chr13:135,467,798...135,587,483
JBrowse link
G ITGB6 integrin subunit beta 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3040752|PMID:12634787)
(MGI:6376388|PMID:30952606)
Ensembl
Ensembl
MGI
PMID:12634787 PMID:30952606 GO_REF:0000107 MGI:3040752 MGI:6376388 NCBI chr15:67,041,516...67,175,409
Ensembl chr15:67,041,519...67,175,234
JBrowse link
G ITGB8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6376388|PMID:30952606) Ensembl
Ensembl
MGI
PMID:30952606 GO_REF:0000107 MGI:6376388 NCBI chr 9:89,342,245...89,450,701
Ensembl chr 9:89,341,141...89,450,679
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) BHF-UCL PMID:9732876 NCBI chr 6:153,686,425...153,687,635 JBrowse link
G LOC100152566 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 7:7,382,731...7,422,199
Ensembl chr 7:7,328,214...7,422,197
JBrowse link
G LOC100525721 dual specificity protein phosphatase 15 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:35,540,615...35,550,493
Ensembl chr17:35,538,491...35,550,432
JBrowse link
G LPXN leupaxin involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 2:12,534,780...12,582,756
Ensembl chr 2:12,534,840...12,582,745
JBrowse link
G LRRC32 leucine rich repeat containing 32 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:10,802,228...10,815,892
Ensembl chr 9:10,801,946...10,817,930
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:72661|PMID:7730318)
(MGI:2389565|PMID:12379497)
Ensembl
Ensembl
MGI
PMID:7730318 PMID:12379497 GO_REF:0000107 MGI:2389565 MGI:72661 NCBI chr 2:6,701,455...6,720,191
Ensembl chr 2:6,701,340...6,720,172
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2386340|PMID:12208849) Ensembl
Ensembl
MGI
PMID:12208849 GO_REF:0000107 MGI:2386340 NCBI chr 6:48,831,018...48,861,503
Ensembl chr 6:48,831,014...48,861,507
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (MGI:2674169|PMID:12941696) MGI PMID:12941696 MGI:2674169 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,871,799...35,946,987
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607216|PMID:16145668) MGI PMID:16145668 MGI:3607216 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
JBrowse link
G MIR143 microRNA mir-143 acts_upstream_of_or_within ISO (MGI:6208917|PMID:29925839) MGI PMID:29925839 MGI:6208917 NCBI chr 2:150,578,738...150,578,817
Ensembl chr 2:150,578,738...150,578,817
JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of_or_within ISO (MGI:6208917|PMID:29925839) MGI PMID:29925839 MGI:6208917 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211
JBrowse link
G MSTN myostatin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2676508|PMID:12595574) Ensembl
Ensembl
MGI
PMID:12595574 GO_REF:0000107 MGI:2676508 NCBI chr15:94,623,526...94,628,440
Ensembl chr15:94,620,269...94,628,546
JBrowse link
G MTMR4 myotubularin related protein 4 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr12:34,745,232...34,771,315
Ensembl chr12:34,745,236...34,771,233
JBrowse link
G NLK nemo like kinase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:44,402,990...44,553,527
Ensembl chr12:44,403,021...44,553,518
JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:133,470,641...133,496,218
Ensembl chr13:133,470,643...133,496,264
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,159...14,241,197
JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850 NCBI chr 1:96,401,635...96,545,798
Ensembl chr 1:96,441,413...96,545,777
JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3054278|PMID:15356634) Ensembl
Ensembl
MGI
PMID:15356634 GO_REF:0000107 MGI:3054278 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,048...59,450,150
JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,613...2,896,060
JBrowse link
G PTPRK protein tyrosine phosphatase receptor type K involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:34,693,363...35,258,699
Ensembl chr 1:34,693,367...35,258,701
JBrowse link
G PXN paxillin involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr14:40,227,894...40,278,785
Ensembl chr14:40,227,894...40,278,766
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3797158|PMID:18212064) Ensembl
Ensembl
MGI
PMID:18212064 GO_REF:0000107 MGI:3797158 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,176
JBrowse link
G SMAD1 SMAD family member 1 involved_in IEA InterPro
InterPro
Ensembl
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 8:82,907,557...82,987,909
Ensembl chr 8:82,908,527...82,968,994
JBrowse link
G SMAD2 SMAD family member 2 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:2153598|PMID:11557747), (MGI:3032478|PMID:14749725)
(MGI:3797158|PMID:18212064)
Ensembl
InterPro
Ensembl
GO_Central
MGI
InterPro
GO_Central
PMID:11557747 PMID:14749725 PMID:18212064 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:2153598 MGI:3032478 MGI:3797158 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,358
JBrowse link
G SMAD3 SMAD family member 3 involved_in
acts_upstream_of_or_within
IEA
IBA
ISS
ISO
(PMID:21873635)
(MGI:3505646|PMID:15239668), (MGI:3690196|PMID:16619037), (MGI:5300220|PMID:21937600)
TGFbeta-1 dependent, in pancreatic stellate cells
Ensembl
InterPro
GO_Central
Ensembl
UniProt
MGI
RGD
UniProt
GO_Central
PMID:15239668 PMID:16371439 PMID:16619037 PMID:16891311 PMID:21873635 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:3505646 MGI:3690196 MGI:5300220 RGD:1625706 RGD:2300404 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,083...165,124,454
JBrowse link
G SMAD4 SMAD family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:3797158|PMID:18212064)
(PMID:21873635)
InterPro
MGI
InterPro
Ensembl
GO_Central
GO_Central
PMID:18212064 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:3797158 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029
JBrowse link
G SMAD5 SMAD family member 5 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:1935017|PMID:11376112)
InterPro
GO_Central
InterPro
Ensembl
MGI
GO_Central
PMID:11376112 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:1935017 NCBI chr 2:138,287,635...138,344,092
Ensembl chr 2:138,287,443...138,344,769
JBrowse link
G SMAD6 SMAD family member 6 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 1:164,652,602...164,735,084
Ensembl chr 1:164,657,086...164,735,083
JBrowse link
G SMAD7 SMAD family member 7 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2153598|PMID:11557747)
GO_Central
GO_Central
Ensembl
InterPro
MGI
InterPro
PMID:11557747 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:2153598 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,510,229...98,542,382
JBrowse link
G SMAD9 SMAD family member 9 involved_in IEA
IBA
(PMID:21873635) InterPro
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr11:12,705,652...12,727,981
Ensembl chr11:12,705,359...12,763,008
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:15,227,850...15,245,679
Ensembl chr 2:15,227,829...15,245,667
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2447107|PMID:12464436) Ensembl
Ensembl
MGI
PMID:12464436 GO_REF:0000107 MGI:2447107 NCBI chr 5:8,827,363...8,852,814
Ensembl chr 5:8,826,840...8,852,776
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within
ISS
IBA
IEA
ISO
(PMID:21873635)
(MGI:2386340|PMID:12208849), (MGI:5543310|PMID:23868260)
UniProt
UniProt
GO_Central
Ensembl
GO_Central
RGD
MGI
PMID:12208849 PMID:21873635 PMID:23868260 PMID:33360052 GO_REF:0000024 GO_REF:0000107 MGI:2386340 MGI:5543310 RGD:127229954 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IBA
IEA
(PMID:21873635) UniProt
UniProt
GO_Central
Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,424...8,405,771
JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in ISS
IEA
IBA
(PMID:21873635) AgBase
Ensembl
AgBase
GO_Central
GO_Central
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:99,133,873...99,162,239
Ensembl chr 7:99,133,511...99,162,232
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISS
ISO
(PMID:21873635)
(MGI:2679137|PMID:14580334), (MGI:3575204|PMID:15820682)
(MGI:1933434|PMID:11285230)
(MGI:5298182|PMID:21832243)
(MGI:3703113|PMID:17078885)
GO_Central
GO_Central
Ensembl
AgBase
MGI
RGD
AgBase
PMID:8272871 PMID:11285230 PMID:14580334 PMID:15820682 PMID:17078885 More... GO_REF:0000024 GO_REF:0000107 MGI:1933434 MGI:2679137 MGI:3575204 MGI:3703113 MGI:5298182 RGD:2302021 RGD:2302517 RGD:737663 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,859,270...240,918,528
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:4949016|PMID:21420963)
Ensembl
Ensembl
GO_Central
MGI
RGD
GO_Central
PMID:18684975 PMID:21420963 PMID:21873635 GO_REF:0000107 MGI:4949016 RGD:2302517 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,491...16,878,165
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IBA
IEA
ISS
(PMID:21873635)
(PMID:1333192)
GO_Central
GO_Central
Ensembl
BHF-UCL
BHF-UCL
Ensembl
PMID:1333192 PMID:21873635 GO_REF:0000107 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,101,190...125,316,796
JBrowse link
G TGFBR3L transforming growth factor beta receptor 3 like involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 2:71,294,960...71,298,172
Ensembl chr 2:71,294,968...71,297,927
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3797158|PMID:18212064) Ensembl
Ensembl
MGI
PMID:18212064 GO_REF:0000107 MGI:3797158 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:98,629,116...98,678,322
Ensembl chr 6:98,623,439...98,678,258
JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:26,964,380...27,082,549
Ensembl chr 5:26,964,510...27,097,458
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:36,736,049...36,888,702
Ensembl chr  X:36,760,819...36,885,275
JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2676508|PMID:12595574) Ensembl
Ensembl
MGI
PMID:12595574 GO_REF:0000107 MGI:2676508 NCBI chr12:27,093,241...27,100,423
Ensembl chr12:27,093,679...27,100,423
JBrowse link
G ZFYVE9 zinc finger FYVE-type containing 9 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:159,872,735...160,074,476
Ensembl chr 6:159,874,026...160,074,413
JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:81,409,067...81,647,808
Ensembl chr14:81,455,127...81,647,949
JBrowse link
G ZMIZ2 zinc finger MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850 NCBI chr18:50,579,650...50,598,921
Ensembl chr18:50,579,653...50,598,653
JBrowse link
G ZYX zyxin involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr18:6,861,072...6,870,256
Ensembl chr18:6,861,072...6,870,273
JBrowse link
transforming growth factor beta receptor signaling pathway involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2677178|PMID:14511481) Ensembl
Ensembl
MGI
PMID:14511481 GO_REF:0000107 MGI:2677178 NCBI chr14:73,350,358...73,357,064
Ensembl chr14:73,349,965...73,360,618
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    response to stimulus 9374
      response to endogenous stimulus 1968
        response to transforming growth factor beta 280
          cellular response to transforming growth factor beta stimulus 271
            negative regulation of cellular response to transforming growth factor beta stimulus 4
            positive regulation of cellular response to transforming growth factor beta stimulus + 33
            regulation of cellular response to transforming growth factor beta stimulus + 128
            transforming growth factor beta receptor signaling pathway + 190
Path 2
Term Annotations click to browse term
  biological_process 16975
    response to stimulus 9374
      response to chemical 5721
        response to organic substance 3621
          response to growth factor 810
            cellular response to growth factor stimulus 770
              cellular response to transforming growth factor beta stimulus 271
                negative regulation of cellular response to transforming growth factor beta stimulus 4
                positive regulation of cellular response to transforming growth factor beta stimulus + 33
                regulation of cellular response to transforming growth factor beta stimulus + 128
                transforming growth factor beta receptor signaling pathway + 190
paths to the root