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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to xenobiotic stimulus
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Accession:GO:0071466 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:related_synonym: cellular response to drug
 alt_id: GO:0035690


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cellular response to xenobiotic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO pitavastatin, clofibrate, GW 6471 RGD PMID:21554872 RGD:21408554 NCBI chrNW_004936559:7,177,887...7,312,660 JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004936469:10,521,576...10,599,005 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20628055) BHF-UCL PMID:20628055 NCBI chrNW_004936652:1,289,445...1,329,236 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO (MGI:3822392|PMID:19109165) UniProt PMID:19109165 MGI:3822392 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adss1 adenylosuccinate synthase 1 ISO cyclosporin A RGD PMID:10636885 RGD:5135512 NCBI chrNW_004936621:655,004...667,608 JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO losartan, metformin RGD PMID:22467055 RGD:7245559 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
G Aim2 absent in melanoma 2 acts_upstream_of_or_within ISO (PMID:19158679) MGI PMID:19158679 NCBI chrNW_004936740:1,447,869...1,460,836 JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (MGI:5294542|PMID:17239933) UniProt PMID:17239933 MGI:5294542 NCBI chrNW_004936601:3,502,844...3,510,919 JBrowse link
G Asic2 acid sensing ion channel subunit 2 ISO amiloride RGD PMID:12736332 RGD:1298620 NCBI chrNW_004936538:938,266...2,011,154 JBrowse link
G Bcl2l1 BCL2 like 1 ISO carboplatin RGD PMID:18483861 RGD:2293312 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:5467188|PMID:22628551) MGI PMID:22628551 MGI:5467188 NCBI chrNW_004936592:4,728,371...4,833,830 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO N-phosphonoacetyl-L-aspartate RGD PMID:8548770 RGD:5132280 NCBI chrNW_004936493:5,308,268...5,332,934 JBrowse link
G Cebpa CCAAT enhancer binding protein alpha ISO rosiglitazone RGD PMID:1377818 RGD:69946 NCBI chrNW_004936570:2,513,561...2,516,213 JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:19800881) UniProt PMID:19800881 NCBI chrNW_004936596:2,442,978...2,467,184 JBrowse link
G Chek2 checkpoint kinase 2 ISO alpha-difluoromethylornithine RGD PMID:21745814 RGD:10401653 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:6150543|PMID:29581031) MGI PMID:29581031 MGI:6150543 NCBI chrNW_004936619:2,447,686...2,479,589 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:20613717 RGD:11352688 NCBI chrNW_004936469:39,794,613...39,798,448 JBrowse link
G Ddc dopa decarboxylase ISO L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chrNW_004936686:1,322,153...1,405,434 JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO (PMID:20435919) UniProt PMID:20435919 NCBI chrNW_004936641:379,112...384,711 JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004936561:6,894,827...6,901,058 JBrowse link
G Edn1 endothelin 1 ISO cyclosporine RGD PMID:8129032 RGD:8662286 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO cilostazol RGD PMID:21390260 RGD:10401124 NCBI chrNW_004936859:740,620...744,534 JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 ISO flutamide RGD PMID:24793618 RGD:10045571 NCBI chrNW_004936541:1,216,584...1,259,355 JBrowse link
G Egfr epidermal growth factor receptor ISO NADPH oxidase inhibitors VAS2870, apocynin
vorinostat
RGD PMID:21276422 PMID:21389970 RGD:5131459 RGD:5131479 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Egr1 early growth response 1 ISO imipramine RGD PMID:21354245 RGD:5131879 NCBI chrNW_004936531:7,625,956...7,629,041 JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chrNW_004936727:1,648,451...1,663,294 JBrowse link
G Ep300 E1A binding protein p300 ISO valproic acid RGD PMID:20888352 RGD:7364728 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Esr2 estrogen receptor 2 ISO tamoxifen RGD PMID:19279558 RGD:7364795 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Fancb FA complementation group B acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004936470:4,305,220...4,323,456 JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO (PMID:16442285), (PMID:18650089) UniProt PMID:16442285 PMID:18650089 NCBI chrNW_004936626:3,555,835...3,581,651 JBrowse link
G Fgf21 fibroblast growth factor 21 ISO RGD PMID:23118742 RGD:10401886 NCBI chrNW_004936664:2,826,823...2,828,330 JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO (PMID:16359517)
PMID:18374201
UniProt PMID:16359517 PMID:18374201 RGD:8554638 NCBI chrNW_004936472:27,116...57,158 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:17761367) UniProt PMID:17761367 NCBI chrNW_004936671:780,173...827,628 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO isoproterenol RGD PMID:20193759 RGD:9068889 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO amlodipine besylate, amlodipine camsylate RGD PMID:21988238 RGD:10402816 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:18757512 RGD:11354916 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (PMID:1315531) UniProt PMID:1315531 NCBI chrNW_004936890:154,252...157,044 JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO (PMID:19158679) MGI PMID:19158679 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:12242040 RGD:4999478 NCBI chrNW_004936541:2,822,789...2,871,069 JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 ISO fluoxetine RGD PMID:11543764 RGD:9685702 NCBI chrNW_004936528:1,351,687...1,393,926 JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:17293496 RGD:7247436 NCBI chrNW_004936605:4,370,222...4,828,972 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO PMID:10219239
(PMID:10219239)
BHF-UCL PMID:10219239 RGD:633041 NCBI chrNW_004936500:8,067,009...8,072,383 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:7604285) BHF-UCL PMID:7604285 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:9108097) BHF-UCL PMID:9108097 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G LOC101956765 corticotropin releasing hormone binding protein involved_in ISO (MGI:5315350|PMID:15976007) UniProt PMID:15976007 MGI:5315350 NCBI chrNW_004936549:64,866...78,272 JBrowse link
G LOC101959784 prion protein acts_upstream_of_or_within ISO (MGI:3607441|PMID:16254249) MGI PMID:16254249 MGI:3607441 NCBI chrNW_004936485:14,104,829...14,118,614 JBrowse link
G LOC101973720 rap guanine nucleotide exchange factor 3 ISO roflumilast RGD PMID:18276108 RGD:9835371 NCBI chrNW_004936512:5,636,197...5,659,606 JBrowse link
G Mcm7 minichromosome maintenance complex component 7 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004936543:238,573...246,746 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5284785|PMID:16775627) UniProt PMID:16775627 MGI:5284785 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO ibuprophen RGD PMID:19847888 RGD:7207385 NCBI chrNW_004936551:5,167,909...5,175,149 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO emodin
(PMID:17873522), (PMID:19179467)
(MGI:5306576|PMID:19179467)
RGD
UniProt
PMID:17873522 PMID:17886230 PMID:19179467 MGI:5306576 RGD:10059617 NCBI chrNW_004936470:20,480,844...20,485,955 JBrowse link
G Mylk myosin light chain kinase acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004936725:1,418,930...1,594,697 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within ISO (MGI:5619708|PMID:24486487) MGI PMID:24486487 MGI:5619708 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:18757402) UniProt PMID:18757402 NCBI chrNW_004936555:7,087,677...7,091,334 JBrowse link
G Nos2 nitric oxide synthase 2 acts_upstream_of_or_within ISO (MGI:5619708|PMID:24486487) MGI PMID:24486487 MGI:5619708 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:27090119 PMID:29235094 RGD:15042872 RGD:15090804 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
G Pax6 paired box 6 ISO pramipexole RGD PMID:19619535 RGD:8552332 NCBI chrNW_004936533:5,952,529...5,980,889 JBrowse link
G Pcna proliferating cell nuclear antigen acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004936485:13,766,221...13,771,215 JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO (PMID:14687666) UniProt PMID:14687666 NCBI chrNW_004936498:1,856,256...1,944,405 JBrowse link
G Pde4a phosphodiesterase 4A acts_upstream_of_or_within ISO (MGI:1927461|PMID:11267656) MGI PMID:11267656 MGI:1927461 NCBI chrNW_004936659:742,969...770,473 JBrowse link
G Pde4b phosphodiesterase 4B acts_upstream_of_or_within ISO (MGI:1927461|PMID:11267656) MGI PMID:11267656 MGI:1927461 NCBI chrNW_004936591:5,152,491...5,666,728 JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO malotilate RGD PMID:3012070 RGD:5135033 NCBI chrNW_004936482:18,606,124...18,648,989 JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent 1E involved_in ISO (PMID:20801214) UniProt PMID:20801214 NCBI chrNW_004936490:4,285,770...4,428,213 JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:20801214) UniProt PMID:20801214 NCBI chrNW_004936619:1,786,223...1,816,083 JBrowse link
G Ppp1r12a protein phosphatase 1 regulatory subunit 12A acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004936698:811,399...948,631 JBrowse link
G Ppp1r14a protein phosphatase 1 regulatory inhibitor subunit 14A acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004936801:1,028,246...1,038,093 JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO methapyrilene RGD PMID:23274394 RGD:9999168 NCBI chrNW_004936664:2,910,609...2,914,205 JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B ISO haloperidol RGD PMID:16844384 RGD:10043796 NCBI chrNW_004936490:11,497,389...11,514,191 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004936518:1,817,051...1,843,376 JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 acts_upstream_of_or_within ISO (MGI:5607205|PMID:23918774) MGI PMID:23918774 MGI:5607205 NCBI chrNW_004936522:4,872,360...4,939,873 JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO theophylline RGD PMID:2484967 RGD:5128599 NCBI chrNW_004936477:10,687,328...10,708,015 JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO rolipram RGD PMID:10908723 RGD:10003157 NCBI chrNW_004936690:275,840...363,752 JBrowse link
G Rap1b RAP1B, member of RAS oncogene family ISO rolipram RGD PMID:10908723 RGD:10003157 NCBI chrNW_004936545:6,567,873...6,578,404 JBrowse link
G Rap2a RAP2A, member of RAS oncogene family involved_in ISO (PMID:22797597) UniProt PMID:22797597 NCBI chrNW_004936472:12,634,563...12,671,656 JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Rbm22 RNA binding motif protein 22 involved_in ISO (PMID:21122810) UniProt PMID:21122810 NCBI chrNW_004936504:4,294,010...4,304,669 JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004936594:829,296...862,615 JBrowse link
G Ren renin ISO secretagogue C4880 RGD PMID:21963836 RGD:6892652 NCBI chrNW_004936567:598,044...607,628 JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:20564196) UniProt PMID:20564196 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
G Rnf149 ring finger protein 149 acts_upstream_of_or_within ISO (MGI:5467188|PMID:22628551) MGI PMID:22628551 MGI:5467188 NCBI chrNW_004936713:74,126...102,051 JBrowse link
G Serpine1 serpin family E member 1 ISO valproic acid RGD PMID:23378038 RGD:8547945 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO (MGI:5442671|PMID:22593622) MGI PMID:22593622 MGI:5442671 NCBI chrNW_004936740:776,557...786,182 JBrowse link
G Slc10a1 solute carrier family 10 member 1 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004936495:12,958,983...12,975,755 JBrowse link
G Slc18a2 solute carrier family 18 member A2 ISO 1-methyl-4-phenylpyridinium, acriflavine RGD PMID:20007701 RGD:5130957 NCBI chrNW_004936486:7,075,373...7,108,984 JBrowse link
G Slco1a2 solute carrier organic anion transporter family member 1A2 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004936548:5,507,085...5,562,624 JBrowse link
G Sox10 SRY-box transcription factor 10 ISO arecaidine RGD PMID:24403178 RGD:12879828 NCBI chrNW_004936492:3,173,770...3,183,423 JBrowse link
G Tfrc transferrin receptor acts_upstream_of_or_within ISO (PMID:16254249) MGI PMID:16254249 NCBI chrNW_004936784:696,738...728,385 JBrowse link
G Th tyrosine hydroxylase ISO L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chrNW_004936794:478,651...486,887 JBrowse link
G Tlr3 toll like receptor 3 ISO methimazole derivative C10 RGD PMID:15661832 RGD:5128798 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:20810912) UniProt PMID:20810912 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Txn thioredoxin ISO dipyridamole RGD PMID:20453393 RGD:5133719 NCBI chrNW_004936559:2,811,786...2,822,528 JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (MGI:5444768|PMID:23064229) MGI PMID:23064229 MGI:5444768 NCBI chrNW_004936482:8,551,749...8,563,586 JBrowse link
G Umps uridine monophosphate synthetase ISO pyrazofurin RGD PMID:6134725 RGD:5132277 NCBI chrNW_004936725:553,278...564,846 JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:22326847 RGD:7421605 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
arsonoacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase involved_in ISO PMID:11790780
(PMID:25997655)
UniProt PMID:11790780 PMID:25997655 RGD:625365 NCBI chrNW_004936600:3,050,946...3,069,786 JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:25997655) UniProt PMID:25997655 NCBI chrNW_004936500:13,086,873...13,099,814 JBrowse link
carbon tetrachloride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 ISO RGD PMID:15270078 RGD:4891447 NCBI chrNW_004936475:334,275...351,051 JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101969148 cytochrome P450 1A1 ISO 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:12914780 PMID:15812643 RGD:2306662 RGD:2306673 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
insecticide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b3 hydroxysteroid 17-beta dehydrogenase 3 ISO methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chrNW_004936487:228,301...282,495 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO Deltamethrin (pyrethroid) RGD PMID:16169030 RGD:2306660 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G Star steroidogenic acute regulatory protein ISO methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chrNW_004936710:1,523,289...1,530,181 JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon3 paraoxonase 3 ISO RGD PMID:12946270 RGD:1303961 NCBI chrNW_004936585:4,902,430...4,928,377 JBrowse link
propylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO (MGI:5320264|PMID:21795692) BHF-UCL PMID:21795692 MGI:5320264 NCBI chrNW_004936669:814,330...838,881 JBrowse link
regulation of cellular response to drug term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:16061642) UniProt PMID:16061642 NCBI chrNW_004936545:3,944,419...3,958,289 JBrowse link
G Ncoa1 nuclear receptor coactivator 1 involved_in ISO (MGI:5297786|PMID:16723356) UniProt PMID:16723356 MGI:5297786 NCBI chrNW_004936493:7,368,393...7,605,754 JBrowse link
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 ISO RGD PMID:18088505 RGD:14700808 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:10725307 RGD:2312871 NCBI chrNW_004936554:4,425,518...4,484,853 JBrowse link
G Cryz crystallin zeta involved_in ISO (PMID:17497241) UniProt PMID:17497241 NCBI chrNW_004936571:2,002,388...2,033,423 JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (MGI:5487534|PMID:19262426) MGI PMID:19262426 MGI:5487534 NCBI chrNW_004936481:15,737,491...15,767,344 JBrowse link
G Gstm3 glutathione S-transferase mu 3 involved_in ISO (PMID:8373352) BHF-UCL PMID:8373352 NCBI chrNW_004936704:1,233,909...1,236,864 JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:12928150) UniProt PMID:12928150 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G LOC101958900 glutathione S-transferase Mu 1 involved_in
acts_upstream_of_or_within
ISO (PMID:8373352)
(MGI:2387281|PMID:12069689)
BHF-UCL
MGI
PMID:8373352 PMID:12069689 MGI:2387281 NCBI chrNW_004936704:1,142,990...1,150,491 JBrowse link
G LOC101961588 cytochrome P450 2D17 involved_in ISO (PMID:15039299) BHF-UCL PMID:15039299 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101969421 cytochrome P450 1A2 involved_in ISO (PMID:18356043)
(PMID:18619574)
BHF-UCL PMID:18356043 PMID:18619574 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO (MGI:1931387|PMID:11158245) MGI PMID:11158245 MGI:1931387 NCBI chrNW_004936558:5,162,471...5,302,488 JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 involved_in ISO (PMID:12578355) UniProt PMID:12578355 NCBI chrNW_004936536:6,691,590...6,726,421 JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) UniProt PMID:26878724 NCBI chrNW_004936565:1,380,981...1,389,908 JBrowse link
xenobiotic metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 involved_in ISO PMID:18245269
(PMID:18245269)
UniProt PMID:18245269 RGD:30309924 NCBI chrNW_004936469:10,521,576...10,599,005 JBrowse link
G Aox1 aldehyde oxidase 1 involved_in ISO (MGI:5553225|PMID:23462233)
(PMID:20444863), (PMID:22031625), (PMID:22522748), (PMID:23857892)
UniProt PMID:20444863 PMID:22031625 PMID:22522748 PMID:23462233 PMID:23857892 MGI:5553225 NCBI chrNW_004936825:263,725...332,424 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:18515330 RGD:2303526 NCBI chrNW_004936493:5,308,268...5,332,934 JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO (PMID:18449627) UniProt PMID:18449627 NCBI chrNW_004936500:6,569,708...6,591,266 JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:11744609) BHF-UCL PMID:11744609 NCBI chrNW_004936481:15,885,375...15,910,216 JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISO (PMID:15970797) UniProt PMID:15970797 NCBI chrNW_004936600:1,907,396...1,925,256 JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:1540159) UniProt PMID:1540159 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Guk1 guanylate kinase 1 involved_in ISO (PMID:6306664) UniProt PMID:6306664 NCBI chrNW_004936864:76,707...86,479 JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha involved_in ISO (PMID:17827783) BHF-UCL PMID:17827783 NCBI chrNW_004936530:2,401,053...2,425,989 JBrowse link
G LOC101958062 glutathione S-transferase A4 involved_in ISO (PMID:10329152) UniProt PMID:10329152 NCBI chrNW_004936476:7,873,218...7,888,301 JBrowse link
G LOC101961079 cholesterol 24-hydroxylase involved_in ISO (PMID:20667828) UniProt PMID:20667828 NCBI chrNW_004936604:3,451,853...3,490,688 JBrowse link
G LOC101961588 cytochrome P450 2D17 involved_in ISO (PMID:18356043)
(PMID:19219744)
RGD
BHF-UCL
PMID:8910433 PMID:18356043 PMID:19219744 RGD:728177 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101969148 cytochrome P450 1A1 involved_in ISO (PMID:19219744) BHF-UCL PMID:19219744 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G LOC101969421 cytochrome P450 1A2 acts_upstream_of_or_within
involved_in
ISO (MGI:79217|PMID:8643688)
(PMID:15327587), (PMID:19219744)
MGI
BHF-UCL
PMID:8643688 PMID:15327587 PMID:19219744 MGI:79217 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G LOC101969608 aryl hydrocarbon receptor interacting protein acts_upstream_of_or_within ISO (MGI:86857|PMID:9083006) MGI PMID:9083006 MGI:86857 NCBI chrNW_004936599:2,274,451...2,280,486 JBrowse link
G LOC101970101 cytochrome P450 1B1 involved_in ISO (PMID:22888116) UniProt PMID:22888116 NCBI chrNW_004936663:345,021...355,188 JBrowse link
G LOC101970215 cytochrome P450 2W1 involved_in ISO (PMID:16551781) UniProt PMID:16551781 NCBI chrNW_004936754:1,203,004...1,208,131 JBrowse link
G LOC101970597 sulfotransferase 1C1 involved_in ISO (PMID:28992322) UniProt PMID:28992322 NCBI chrNW_004936729:1,783,124...1,796,723 JBrowse link
G LOC101973029 cytochrome P450 2E1 involved_in ISO (PMID:18356043)
(PMID:19219744)
RGD
BHF-UCL
PMID:18356043 PMID:19219744 PMID:21187827 RGD:4892233 NCBI chrNW_004936486:19,691,822...19,702,684 JBrowse link
G LOC101975674 cytochrome P450 26B1 involved_in ISO (PMID:26937021) UniProt PMID:26937021 NCBI chrNW_004936491:16,010,394...16,028,852 JBrowse link
G LOC101977861 cytochrome P450 26A1 involved_in ISO (PMID:26937021) UniProt PMID:26937021 NCBI chrNW_004936601:1,810,572...1,815,927 JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 acts_upstream_of_or_within ISO (MGI:3577659|PMID:15840715) MGI PMID:15840715 MGI:3577659 NCBI chrNW_004936593:66,098...128,056 JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 involved_in ISO (PMID:12578355) UniProt PMID:12578355 NCBI chrNW_004936536:6,691,590...6,726,421 JBrowse link
G Rora RAR related orphan receptor A involved_in ISO (MGI:5554367|PMID:17666523) UniProt PMID:17666523 MGI:5554367 NCBI chrNW_004936471:21,402,056...21,567,908 JBrowse link
G Rorc RAR related orphan receptor C involved_in ISO (MGI:5554367|PMID:17666523) UniProt PMID:17666523 MGI:5554367 NCBI chrNW_004936580:1,997,640...2,020,649 JBrowse link
G Tpmt thiopurine S-methyltransferase involved_in ISO (PMID:18484748), (PMID:657528) UniProt PMID:657528 PMID:18484748 NCBI chrNW_004936552:3,899,445...3,917,774 JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 involved_in ISO (PMID:21127708) UniProt PMID:21127708 NCBI chrNW_004936501:13,459,400...13,461,864 JBrowse link

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  biological_process 12174
    response to stimulus 6553
      response to chemical 3817
        response to xenobiotic stimulus 597
          cellular response to xenobiotic stimulus 138
            negative regulation of cellular response to drug 0
            positive regulation of cellular response to drug 0
            regulation of cellular response to drug + 2
            xenobiotic metabolic process + 43
paths to the root