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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to xenobiotic stimulus
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Accession:GO:0071466 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:related_synonym: cellular response to drug
 alt_id: GO:0035690


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cellular response to xenobiotic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO pitavastatin, clofibrate, GW 6471 RGD PMID:21554872 RGD:21408554 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004955449:5,412,958...5,511,629
Ensembl chrNW_004955449:5,412,876...5,512,701
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812
JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20628055) BHF-UCL PMID:20628055 NCBI chrNW_004955434:21,786,857...21,810,648
Ensembl chrNW_004955434:21,786,856...21,810,648
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO (MGI:3822392|PMID:19109165) UniProt PMID:19109165 MGI:3822392 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adss1 adenylosuccinate synthase 1 ISO cyclosporin A RGD PMID:10636885 RGD:5135512 NCBI chrNW_004955538:3,179,299...3,196,251
Ensembl chrNW_004955538:3,179,299...3,196,251
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO losartan, metformin RGD PMID:22467055 RGD:7245559 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (MGI:5294542|PMID:17239933) UniProt PMID:17239933 MGI:5294542 NCBI chrNW_004955425:2,258,554...2,267,699
Ensembl chrNW_004955425:2,258,392...2,267,878
JBrowse link
G Asic2 acid sensing ion channel subunit 2 ISO amiloride RGD PMID:12736332 RGD:1298620 NCBI chrNW_004955481:7,850,730...8,093,255
Ensembl chrNW_004955481:7,850,710...8,871,794
JBrowse link
G Bcl2l1 BCL2 like 1 ISO carboplatin RGD PMID:18483861 RGD:2293312 NCBI chrNW_004955422:29,254,440...29,307,104
Ensembl chrNW_004955422:29,254,216...29,308,174
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:5467188|PMID:22628551) MGI PMID:22628551 MGI:5467188 NCBI chrNW_004955494:2,567,238...2,712,708 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO N-phosphonoacetyl-L-aspartate RGD PMID:8548770 RGD:5132280 NCBI chrNW_004955469:9,203,433...9,227,526
Ensembl chrNW_004955469:9,203,434...9,227,865
JBrowse link
G Cd69 CD69 molecule acts_upstream_of_or_within ISO (PMID:19109165) UniProt PMID:19109165 NCBI chrNW_004955413:5,579,037...5,586,238
Ensembl chrNW_004955413:5,579,072...5,587,491
JBrowse link
G Cebpa CCAAT enhancer binding protein alpha ISO rosiglitazone RGD PMID:1377818 RGD:69946 NCBI chrNW_004955468:3,046,544...3,049,217
Ensembl chrNW_004955468:3,047,931...3,049,080
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:19800881) UniProt PMID:19800881 NCBI chrNW_004955524:2,788,672...2,798,068
Ensembl chrNW_004955524:2,788,653...2,796,370
JBrowse link
G Chek2 checkpoint kinase 2 ISO alpha-difluoromethylornithine RGD PMID:21745814 RGD:10401653 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173
JBrowse link
G Crhbp corticotropin releasing hormone binding protein involved_in ISO (MGI:5315350|PMID:15976007) UniProt PMID:15976007 MGI:5315350 NCBI chrNW_004955425:23,953,957...23,966,207
Ensembl chrNW_004955425:23,953,912...23,966,352
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:6150543|PMID:29581031) MGI PMID:29581031 MGI:6150543 NCBI chrNW_004955442:19,358,202...19,388,552
Ensembl chrNW_004955442:19,358,081...19,388,815
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:20613717 RGD:11352688 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
JBrowse link
G Ddc dopa decarboxylase ISO L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chrNW_004955456:3,513,779...3,582,851
Ensembl chrNW_004955456:3,513,042...3,582,911
JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO (PMID:20435919) UniProt PMID:20435919 NCBI chrNW_004955541:3,204,421...3,215,514
Ensembl chrNW_004955541:3,204,055...3,215,565
JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004955422:27,638,625...27,643,261
Ensembl chrNW_004955422:27,633,827...27,642,241
JBrowse link
G Edn1 endothelin 1 ISO cyclosporine RGD PMID:8129032 RGD:8662286 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO cilostazol RGD PMID:21390260 RGD:10401124 NCBI chrNW_004955493:8,661,317...8,663,190 JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 ISO flutamide RGD PMID:24793618 RGD:10045571 NCBI chrNW_004955451:17,655,659...17,690,117
Ensembl chrNW_004955451:17,653,125...17,690,117
JBrowse link
G Egfr epidermal growth factor receptor ISO vorinostat
NADPH oxidase inhibitors VAS2870, apocynin
RGD PMID:21276422 PMID:21389970 RGD:5131459 RGD:5131479 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Egr1 early growth response 1 ISO imipramine RGD PMID:21354245 RGD:5131879 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chrNW_004955437:396,736...411,144
Ensembl chrNW_004955437:396,742...411,144
JBrowse link
G Ep300 E1A binding protein p300 ISO valproic acid RGD PMID:20888352 RGD:7364728 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
JBrowse link
G Esr2 estrogen receptor 2 ISO tamoxifen RGD PMID:19279558 RGD:7364795 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Fancb FA complementation group B acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004955519:3,337,138...3,364,963
Ensembl chrNW_004955519:3,343,446...3,363,814
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO (PMID:16442285), (PMID:18650089) UniProt PMID:16442285 PMID:18650089 NCBI chrNW_004955422:21,537,337...21,569,174
Ensembl chrNW_004955422:21,536,667...21,569,433
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO RGD PMID:23118742 RGD:10401886 NCBI chrNW_004955559:1,818,400...1,821,423
Ensembl chrNW_004955559:1,817,110...1,820,417
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO (PMID:16359517)
PMID:18374201
UniProt PMID:16359517 PMID:18374201 RGD:8554638 NCBI chrNW_004955404:276,397...303,864
Ensembl chrNW_004955404:275,946...304,809
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:17761367) UniProt PMID:17761367 NCBI chrNW_004955483:2,501,751...2,552,855
Ensembl chrNW_004955483:2,502,345...2,552,689
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO isoproterenol RGD PMID:20193759 RGD:9068889 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO amlodipine besylate, amlodipine camsylate RGD PMID:21988238 RGD:10402816 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:18757512 RGD:11354916 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (PMID:1315531) UniProt PMID:1315531 NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816
JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO (PMID:19158679) MGI PMID:19158679 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:12242040 RGD:4999478 NCBI chrNW_004955478:9,788,192...9,830,254 JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 ISO fluoxetine RGD PMID:11543764 RGD:9685702 NCBI chrNW_004955414:32,538,968...32,580,370
Ensembl chrNW_004955414:32,538,938...32,580,370
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 ISO RGD PMID:17293496 RGD:7247436 NCBI chrNW_004955479:2,062,607...2,545,576
Ensembl chrNW_004955479:2,062,608...2,543,125
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 RGD:633041 NCBI chrNW_004955407:33,734,969...33,736,609
Ensembl chrNW_004955407:33,735,148...33,735,513
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:7604285) BHF-UCL PMID:7604285 NCBI chrNW_004955491:5,391,444...5,422,241
Ensembl chrNW_004955491:5,391,384...5,422,241
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:9108097) BHF-UCL PMID:9108097 NCBI chrNW_004955422:14,212,563...14,544,556
Ensembl chrNW_004955422:14,212,553...14,544,556
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004955573:763,358...770,782
Ensembl chrNW_004955573:763,358...775,489
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5284785|PMID:16775627) UniProt PMID:16775627 MGI:5284785 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO emodin
(PMID:17873522), (PMID:19179467)
(MGI:5306576|PMID:19179467)
RGD
UniProt
PMID:17873522 PMID:17886230 PMID:19179467 MGI:5306576 RGD:10059617 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982
JBrowse link
G Mylk myosin light chain kinase acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004955427:22,760,432...23,008,432
Ensembl chrNW_004955427:22,762,221...22,970,508
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within ISO (MGI:5619708|PMID:24486487) MGI PMID:24486487 MGI:5619708 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:18757402) UniProt PMID:18757402 NCBI chrNW_004955403:46,807,846...46,809,924
Ensembl chrNW_004955403:46,806,178...46,836,310
JBrowse link
G Nos2 nitric oxide synthase 2 acts_upstream_of_or_within ISO (MGI:5619708|PMID:24486487) MGI PMID:24486487 MGI:5619708 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:27090119 PMID:29235094 RGD:15042872 RGD:15090804 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751
JBrowse link
G Pax6 paired box 6 ISO pramipexole RGD PMID:19619535 RGD:8552332 NCBI chrNW_004955476:10,058,979...10,074,668
Ensembl chrNW_004955476:10,058,961...10,074,162
JBrowse link
G Pcna proliferating cell nuclear antigen acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004955415:15,744,601...15,748,910
Ensembl chrNW_004955415:15,744,601...15,749,673
JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO (PMID:14687666) UniProt PMID:14687666 NCBI chrNW_004955414:18,765,591...18,826,717
Ensembl chrNW_004955414:18,735,822...18,827,236
JBrowse link
G Pde4a phosphodiesterase 4A acts_upstream_of_or_within ISO (MGI:1927461|PMID:11267656) MGI PMID:11267656 MGI:1927461 NCBI chrNW_004955495:1,659,499...1,693,609
Ensembl chrNW_004955495:1,663,011...1,691,810
JBrowse link
G Pde4b phosphodiesterase 4B acts_upstream_of_or_within ISO (MGI:1927461|PMID:11267656) MGI PMID:11267656 MGI:1927461 NCBI chrNW_004955423:24,464,503...24,906,409
Ensembl chrNW_004955423:24,463,953...24,906,394
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO malotilate RGD PMID:3012070 RGD:5135033 NCBI chrNW_004955447:14,552,846...14,607,416
Ensembl chrNW_004955447:14,574,407...14,607,416
JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent 1E involved_in ISO (PMID:20801214) UniProt PMID:20801214 NCBI chrNW_004955451:3,989,575...4,137,400
Ensembl chrNW_004955451:3,986,715...4,137,134
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:20801214) UniProt PMID:20801214 NCBI chrNW_004955442:17,233,258...17,256,009
Ensembl chrNW_004955442:17,227,723...17,252,383
JBrowse link
G Ppp1r12a protein phosphatase 1 regulatory subunit 12A acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004955405:18,594,191...18,727,345
Ensembl chrNW_004955405:18,596,541...18,727,345
JBrowse link
G Ppp1r14a protein phosphatase 1 regulatory inhibitor subunit 14A acts_upstream_of_or_within ISO (MGI:3805620|PMID:18524939) MGI PMID:18524939 MGI:3805620 NCBI chrNW_004955468:1,174,946...1,179,289
Ensembl chrNW_004955468:1,174,961...1,179,207
JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO methapyrilene RGD PMID:23274394 RGD:9999168 NCBI chrNW_004955559:1,750,227...1,753,607
Ensembl chrNW_004955559:1,750,168...1,753,629
JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B ISO haloperidol RGD PMID:16844384 RGD:10043796 NCBI chrNW_004955451:11,516,548...11,530,263
Ensembl chrNW_004955451:11,516,548...11,530,830
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004955426:25,079,718...25,102,090
Ensembl chrNW_004955426:25,079,718...25,102,090
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 acts_upstream_of_or_within ISO (MGI:5607205|PMID:23918774) MGI PMID:23918774 MGI:5607205 NCBI chrNW_004955464:2,996,608...3,062,197
Ensembl chrNW_004955464:3,003,837...3,062,197
JBrowse link
G Prnp prion protein acts_upstream_of_or_within ISO (MGI:3607441|PMID:16254249) MGI PMID:16254249 MGI:3607441 NCBI chrNW_004955415:15,442,313...15,454,644
Ensembl chrNW_004955415:15,442,313...15,454,644
JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO theophylline RGD PMID:2484967 RGD:5128599 NCBI chrNW_004955480:6,646,088...6,666,866
Ensembl chrNW_004955480:6,646,088...6,669,526
JBrowse link
G Ranbp1 RAN binding protein 1 ISO phenylephrine RGD PMID:25341891 RGD:9835001 NCBI chrNW_004955442:17,985,456...17,992,945
Ensembl chrNW_004955442:17,985,544...17,992,759
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO rolipram RGD PMID:10908723 RGD:10003157 NCBI chrNW_004955435:15,090,521...15,171,397
Ensembl chrNW_004955435:15,150,827...15,171,397
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family ISO rolipram RGD PMID:10908723 RGD:10003157 NCBI chrNW_004955458:15,110,709...15,121,868
Ensembl chrNW_004955458:15,080,778...15,123,203
JBrowse link
G Rap2a RAP2A, member of RAS oncogene family involved_in ISO (PMID:22797597) UniProt PMID:22797597 NCBI chrNW_004955404:12,897,518...12,936,964
Ensembl chrNW_004955404:12,897,240...12,936,964
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO roflumilast RGD PMID:18276108 RGD:9835371 NCBI chrNW_004955500:6,655,056...6,674,311
Ensembl chrNW_004955500:6,655,056...6,674,311
JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO (MGI:5572964|PMID:24726645) MGI PMID:24726645 MGI:5572964 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576
JBrowse link
G Rbm22 RNA binding motif protein 22 involved_in ISO (PMID:21122810) UniProt PMID:21122810 NCBI chrNW_004955415:3,895,272...3,905,801 JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chrNW_004955506:6,574,802...6,612,763
Ensembl chrNW_004955506:6,575,408...6,612,186
JBrowse link
G Ren renin ISO secretagogue C4880 RGD PMID:21963836 RGD:6892652 NCBI chrNW_004955406:40,016,624...40,026,286
Ensembl chrNW_004955406:40,016,630...40,026,286
JBrowse link
G Rnf149 ring finger protein 149 acts_upstream_of_or_within ISO (MGI:5467188|PMID:22628551) MGI PMID:22628551 MGI:5467188 NCBI chrNW_004955470:7,051,552...7,074,187 JBrowse link
G Serpine1 serpin family E member 1 ISO valproic acid RGD PMID:23378038 RGD:8547945 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO (MGI:5442671|PMID:22593622) MGI PMID:22593622 MGI:5442671 NCBI chrNW_004955468:11,623,092...11,632,566
Ensembl chrNW_004955468:11,623,197...11,632,573
JBrowse link
G Slc10a1 solute carrier family 10 member 1 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004955466:597,081...609,254
Ensembl chrNW_004955466:597,204...608,756
JBrowse link
G Slc18a2 solute carrier family 18 member A2 ISO 1-methyl-4-phenylpyridinium, acriflavine RGD PMID:20007701 RGD:5130957 NCBI chrNW_004955431:21,949,553...21,979,679
Ensembl chrNW_004955431:21,949,576...21,979,679
JBrowse link
G Slco1a2 solute carrier organic anion transporter family member 1A2 ISO RGD PMID:27090119 RGD:15090804 NCBI chrNW_004955413:16,821,808...16,910,511
Ensembl chrNW_004955413:16,821,791...16,912,903
JBrowse link
G Sox10 SRY-box transcription factor 10 ISO arecaidine RGD PMID:24403178 RGD:12879828 NCBI chrNW_004955413:24,313,311...24,323,112
Ensembl chrNW_004955413:24,311,783...24,323,315
JBrowse link
G Tfrc transferrin receptor acts_upstream_of_or_within ISO (PMID:16254249) MGI PMID:16254249 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691
JBrowse link
G Th tyrosine hydroxylase ISO L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137
JBrowse link
G Tlr3 toll like receptor 3 ISO methimazole derivative C10 RGD PMID:15661832 RGD:5128798 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:20810912) UniProt PMID:20810912 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (MGI:5444768|PMID:23064229) MGI PMID:23064229 MGI:5444768 NCBI chrNW_004955443:6,367,519...6,379,638
Ensembl chrNW_004955443:6,367,460...6,380,462
JBrowse link
G Umps uridine monophosphate synthetase ISO pyrazofurin RGD PMID:6134725 RGD:5132277 NCBI chrNW_004955427:23,825,529...23,841,427
Ensembl chrNW_004955427:23,825,523...23,841,152
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:22326847 RGD:7421605 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
arsonoacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase involved_in ISO PMID:11790780
(PMID:25997655)
UniProt PMID:11790780 PMID:25997655 RGD:625365 NCBI chrNW_004955485:7,576,627...7,599,005
Ensembl chrNW_004955485:7,575,580...7,599,559
JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:25997655) UniProt PMID:25997655 NCBI chrNW_004955407:28,256,654...28,277,514
Ensembl chrNW_004955407:28,256,649...28,276,460
JBrowse link
carbon tetrachloride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 ISO RGD PMID:15270078 RGD:4891447 NCBI chrNW_004955474:8,180,995...8,202,169
Ensembl chrNW_004955474:8,180,995...8,202,267
JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102010850 cytochrome P450 1A1 ISO 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:12914780 PMID:15812643 RGD:2306662 RGD:2306673 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
insecticide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b3 hydroxysteroid 17-beta dehydrogenase 3 ISO methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chrNW_004955422:23,104,752...23,251,250
Ensembl chrNW_004955422:23,101,795...23,148,999
JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO Deltamethrin (pyrethroid) RGD PMID:16169030 RGD:2306660 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
G Star steroidogenic acute regulatory protein ISO methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chrNW_004955463:13,760,089...13,765,245
Ensembl chrNW_004955463:13,760,089...13,765,244
JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon3 paraoxonase 3 ISO RGD PMID:12946270 RGD:1303961 NCBI chrNW_004955432:11,945,383...11,983,417
Ensembl chrNW_004955432:11,942,922...11,983,504
JBrowse link
propylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO (MGI:5320264|PMID:21795692) BHF-UCL PMID:21795692 MGI:5320264 NCBI chrNW_004955513:5,154,864...5,178,636
Ensembl chrNW_004955513:5,154,864...5,178,636
JBrowse link
regulation of cellular response to drug term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:16061642) UniProt PMID:16061642 NCBI chrNW_004955458:12,493,790...12,624,805 JBrowse link
G Ncoa1 nuclear receptor coactivator 1 involved_in ISO (MGI:5297786|PMID:16723356) UniProt PMID:16723356 MGI:5297786 NCBI chrNW_004955469:6,676,780...6,892,587
Ensembl chrNW_004955469:6,794,821...6,892,566
JBrowse link
trichloroethylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102004212 cytochrome P450 2F3 ISO RGD PMID:15987776 RGD:2301693 NCBI chrNW_004955578:530,094...541,951
Ensembl chrNW_004955578:531,353...541,684
JBrowse link
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 ISO RGD PMID:18088505 RGD:14700808 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812
JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:10725307 RGD:2312871 NCBI chrNW_004955403:24,190,674...24,235,354
Ensembl chrNW_004955403:24,190,674...24,236,780
JBrowse link
G Cryz crystallin zeta involved_in ISO (PMID:17497241) UniProt PMID:17497241 NCBI chrNW_004955423:17,952,783...17,975,982
Ensembl chrNW_004955423:17,955,222...17,975,982
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (MGI:5487534|PMID:19262426) MGI PMID:19262426 MGI:5487534 NCBI chrNW_004955406:11,967,045...11,987,105
Ensembl chrNW_004955406:11,967,003...11,988,887
JBrowse link
G Gstm3 glutathione S-transferase mu 3 involved_in ISO (PMID:8373352) BHF-UCL PMID:8373352 NCBI chrNW_004955435:13,253,947...13,256,965
Ensembl chrNW_004955435:13,253,947...13,256,965
JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within
ISO (PMID:8373352)
(MGI:2387281|PMID:12069689)
BHF-UCL
MGI
PMID:8373352 PMID:12069689 MGI:2387281 NCBI chrNW_004955435:13,064,691...13,069,734
Ensembl chrNW_004955435:13,063,966...13,210,264
JBrowse link
G LOC102010322 cytochrome P450 1A2 involved_in ISO (PMID:18356043)
(PMID:18619574)
BHF-UCL PMID:18356043 PMID:18619574 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942
JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO (MGI:1931387|PMID:11158245) MGI PMID:11158245 MGI:1931387 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 involved_in ISO (PMID:12578355) UniProt PMID:12578355 NCBI chrNW_004955427:19,459,936...19,487,276
Ensembl chrNW_004955427:19,459,936...19,487,276
JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) UniProt PMID:26878724 NCBI chrNW_004955431:1,767,971...1,775,555
Ensembl chrNW_004955431:1,767,525...1,775,555
JBrowse link
xenobiotic metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 involved_in ISO (PMID:18245269) UniProt PMID:18245269 RGD:30309924 NCBI chrNW_004955449:5,412,958...5,511,629
Ensembl chrNW_004955449:5,412,876...5,512,701
JBrowse link
G Aip aryl hydrocarbon receptor interacting protein acts_upstream_of_or_within ISO (MGI:86857|PMID:9083006) MGI PMID:9083006 MGI:86857 NCBI chrNW_004955422:17,997,683...18,003,888
Ensembl chrNW_004955422:17,997,683...18,004,201
JBrowse link
G Aox1 aldehyde oxidase 1 involved_in ISO (MGI:5553225|PMID:23462233)
(PMID:20444863), (PMID:22031625), (PMID:22522748), (PMID:23857892)
UniProt PMID:20444863 PMID:22031625 PMID:22522748 PMID:23462233 PMID:23857892 MGI:5553225 NCBI chrNW_004955403:827,538...875,856
Ensembl chrNW_004955403:828,066...872,218
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:18515330 RGD:2303526 NCBI chrNW_004955469:9,203,433...9,227,526
Ensembl chrNW_004955469:9,203,434...9,227,865
JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO (PMID:18449627) UniProt PMID:18449627 NCBI chrNW_004955407:35,351,601...35,354,510 JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO (MGI:5487534|PMID:19262426) MGI PMID:19262426 MGI:5487534 NCBI chrNW_004955406:11,882,656...11,915,875
Ensembl chrNW_004955406:11,881,882...11,916,323
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:11744609) BHF-UCL PMID:11744609 NCBI chrNW_004955406:11,851,694...11,875,314
Ensembl chrNW_004955406:11,851,637...11,876,843
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISO (PMID:20947616), (PMID:28783300) UniProt PMID:20947616 PMID:28783300 NCBI chrNW_004955568:1,225,136...1,247,352
Ensembl chrNW_004955568:1,224,843...1,250,729
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:1540159) UniProt PMID:1540159 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428
JBrowse link
G Guk1 guanylate kinase 1 involved_in ISO (PMID:6306664) UniProt PMID:6306664 NCBI chrNW_004955581:299,010...305,032
Ensembl chrNW_004955581:299,280...305,032
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha involved_in ISO (PMID:17827783) BHF-UCL PMID:17827783 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G LOC102009223 cytochrome P450 1B1 involved_in ISO (PMID:22888116) UniProt PMID:22888116 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131
JBrowse link
G LOC102010322 cytochrome P450 1A2 acts_upstream_of_or_within
involved_in
ISO (MGI:79217|PMID:8643688)
(PMID:15327587), (PMID:19219744)
MGI
BHF-UCL
PMID:8643688 PMID:15327587 PMID:19219744 MGI:79217 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942
JBrowse link
G LOC102010850 cytochrome P450 1A1 involved_in ISO (PMID:19219744) BHF-UCL PMID:19219744 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
G LOC102016571 cytochrome P450 2W1 involved_in ISO (PMID:16551781) UniProt PMID:16551781 NCBI chrNW_004955460:8,705,068...8,711,266
Ensembl chrNW_004955460:8,705,068...8,712,121
JBrowse link
G LOC102023166 cytochrome P450 26B1 involved_in ISO (PMID:26937021) UniProt PMID:26937021 NCBI chrNW_004955424:13,336,189...13,355,368
Ensembl chrNW_004955424:13,336,189...13,355,423
JBrowse link
G LOC102026028 cytochrome P450 2E1 involved_in ISO (PMID:19219744)
(PMID:18356043)
RGD
BHF-UCL
PMID:18356043 PMID:19219744 PMID:21187827 RGD:4892233 NCBI chrNW_004955507:6,293,162...6,303,255
Ensembl chrNW_004955507:6,289,576...6,304,193
JBrowse link
G LOC102030124 cholesterol 24-hydroxylase involved_in ISO (PMID:20667828) UniProt PMID:20667828 NCBI chrNW_004955438:20,961,621...20,986,260
Ensembl chrNW_004955438:20,961,365...20,985,749
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 acts_upstream_of_or_within ISO (MGI:3577659|PMID:15840715) MGI PMID:15840715 MGI:3577659 NCBI chrNW_004955420:2,666,905...2,725,814
Ensembl chrNW_004955420:2,663,661...2,725,814
JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 involved_in ISO (PMID:12578355) UniProt PMID:12578355 NCBI chrNW_004955427:19,459,936...19,487,276
Ensembl chrNW_004955427:19,459,936...19,487,276
JBrowse link
G Rora RAR related orphan receptor A involved_in ISO (MGI:5554367|PMID:17666523) UniProt PMID:17666523 MGI:5554367 NCBI chrNW_004955450:14,262,199...14,434,611
Ensembl chrNW_004955450:14,262,190...14,425,233
JBrowse link
G Rorc RAR related orphan receptor C involved_in ISO (MGI:5554367|PMID:17666523) UniProt PMID:17666523 MGI:5554367 NCBI chrNW_004955589:590,653...616,784
Ensembl chrNW_004955589:590,743...616,694
JBrowse link
G Tpmt thiopurine S-methyltransferase involved_in ISO (PMID:18484748), (PMID:657528) UniProt PMID:657528 PMID:18484748 NCBI chrNW_004955483:8,052,867...8,072,235
Ensembl chrNW_004955483:8,052,849...8,072,764
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 involved_in ISO (PMID:21127708) UniProt PMID:21127708 NCBI chrNW_004955493:7,928,516...7,931,265 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11981
    response to stimulus 6456
      response to chemical 3773
        response to xenobiotic stimulus 588
          cellular response to xenobiotic stimulus 133
            negative regulation of cellular response to drug 0
            positive regulation of cellular response to drug 0
            regulation of cellular response to drug + 2
            xenobiotic metabolic process + 40
paths to the root